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citrate <=> isocitrate

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catalystActivity	[CatalystActivity:1118558] aconitate hydratase activity of ACO [mitochondrial matrix]
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:1138250] RiceCyc:ACONITATEDEHYDR-RXN
dbId	1119632
displayName	citrate <=> isocitrate
eventOf	[Pathway:R-OSA-1119533] TCA cycle (plant) - Oryza sativa
followingEvent	[Reaction:R-OSA-1120194] isocitrate + NAD+ => 2-oxoglutarate + CO2 + NADH + H+ - Oryza sativa
input	[SimpleEntity:R-ALL-29654] CIT [mitochondrial matrix]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	citrate <=> isocitrate Aconitate hydratase
orthologousEvent	[Reaction:R-AIP-1119632] citrate <=> isocitrate - Arachis ipaensis [Reaction:R-GSO-1119632] citrate <=> isocitrate - Glycine soja [Reaction:R-BRA-1119632] citrate <=> isocitrate - Brassica rapa [Reaction:R-BDI-1119632] citrate <=> isocitrate - Brachypodium distachyon [Reaction:R-MGU-1119632] citrate <=> isocitrate - Erythranthe guttata [Reaction:R-MES-1119632] citrate <=> isocitrate - Manihot esculenta [Reaction:R-CCA-1119632] citrate <=> isocitrate - Cajanus cajan [Reaction:R-NCO-1119632] citrate <=> isocitrate - Nymphaea colorata [Reaction:R-TUR-1119632] citrate <=> isocitrate - Triticum urartu [Reaction:R-EGR-1119632] citrate <=> isocitrate - Eucalyptus grandis [Reaction:R-LPE-1119632] citrate <=> isocitrate - Leersia perrieri [Reaction:R-PAV-1119632] citrate <=> isocitrate - Prunus avium [Reaction:R-ECU-1119632] citrate <=> isocitrate - Eragrostis curvula [Reaction:R-CBA-1119632] citrate <=> isocitrate - Chara braunii [Reaction:R-PPE-1119632] citrate <=> isocitrate - Prunus persica [Reaction:R-ZJA-1119632] citrate <=> isocitrate - Zoysia japonica [Reaction:R-CSI-1119632] citrate <=> isocitrate - Citrus sinensis [Reaction:R-SIT-1119632] citrate <=> isocitrate - Setaria italica [Reaction:R-OGL-1119632] citrate <=> isocitrate - Oryza glaberrima [Reaction:R-TTU-1119632] citrate <=> isocitrate - Triticum turgidum [Reaction:R-AHY-1119632] citrate <=> isocitrate - Arachis hypogaea [Reaction:R-VRA-1119632] citrate <=> isocitrate - Vigna radiata [Reaction:R-QSU-1119632] citrate <=> isocitrate - Quercus suber [Reaction:R-GRA-1119632] citrate <=> isocitrate - Gossypium raimondii [Reaction:R-PED-1119632] citrate <=> isocitrate - Phyllostachys edulis [Reaction:R-OOF-1119632] citrate <=> isocitrate - Oryza officinalis [Reaction:R-CCL-1119632] citrate <=> isocitrate - Citrus clementina [Reaction:R-NNU-1119632] citrate <=> isocitrate - Nelumbo nucifera [Reaction:R-PSA-1119632] citrate <=> isocitrate - Pisum sativum [Reaction:R-OLO-1119632] citrate <=> isocitrate - Oryza longistaminata [Reaction:R-MPO-1119632] citrate <=> isocitrate - Marchantia polymorpha [Reaction:R-ZMY-1119632] citrate <=> isocitrate - Zea mays ver5 [Reaction:R-OBA-1119632] citrate <=> isocitrate - Oryza barthii [Reaction:R-HVU-1119632] citrate <=> isocitrate - Hordeum vulgare [Reaction:R-DEX-1119632] citrate <=> isocitrate - Digitaria exilis [Reaction:R-SMO-1119632] citrate <=> isocitrate - Selaginella moellendorffii [Reaction:R-AHA-1119632] citrate <=> isocitrate - Arabidopsis halleri [Reaction:R-CSC-1119632] citrate <=> isocitrate - Cannabis sativa [Reaction:R-TTI-1119632] citrate <=> isocitrate - Triticum timopheevii subsp. timopheevii [Reaction:R-MTR-1119632] citrate <=> isocitrate - Medicago truncatula [Reaction:R-ADU-1119632] citrate <=> isocitrate - Arachis duranensis [Reaction:R-PHA-1119632] citrate <=> isocitrate - Panicum hallii ("FIL2") [Reaction:R-FVE-1119632] citrate <=> isocitrate - Fragaria vesca [Reaction:R-ZMA-1119632] citrate <=> isocitrate - Zea mays [Reaction:R-CCP-1119632] citrate <=> isocitrate - Corchorus capsularis [Reaction:R-OGU-1119632] citrate <=> isocitrate - Oryza glumaepatula [Reaction:R-LST-1119632] citrate <=> isocitrate - Lathyrus sativus [Reaction:R-JCU-1119632] citrate <=> isocitrate - Jatropha curcas [Reaction:R-HLP-1119632] citrate <=> isocitrate - Humulus lupulus var. lupulus [Reaction:R-CCI-1119632] citrate <=> isocitrate - Corymbia citriodora [Reaction:R-CRU-1119632] citrate <=> isocitrate - Capsella rubella [Reaction:R-ATH-1119632] citrate <=> isocitrate - Arabidopsis thaliana [Reaction:R-SSP-1119632] citrate <=> isocitrate - Saccharum spontaneum [Reaction:R-ASA-1119632] citrate <=> isocitrate - Avena sativa [Reaction:R-VAN-1119632] citrate <=> isocitrate - Vigna angularis [Reaction:R-ECG-1119632] citrate <=> isocitrate - Echinochloa crus-galli [Reaction:R-TPR-1119632] citrate <=> isocitrate - Trifolium pratense [Reaction:R-BJU-1119632] citrate <=> isocitrate - Brassica juncea [Reaction:R-CSK-1119632] citrate <=> isocitrate - Cannabis sativa subsp. indica [Reaction:R-VVN-1119632] citrate <=> isocitrate - Vitis vinifera [Reaction:R-CLA-1119632] citrate <=> isocitrate - Citrullus lanatus [Reaction:R-PTI-1119632] citrate <=> isocitrate - Populus trichocarpa [Reaction:R-PHH-1119632] citrate <=> isocitrate - Panicum hallii var. hallii ("HAL2") [Reaction:R-OPU-1119632] citrate <=> isocitrate - Oryza punctata [Reaction:R-OGR-1119632] citrate <=> isocitrate - Oryza meyeriana var. granulata [Reaction:R-ALY-1119632] citrate <=> isocitrate - Arabidopsis lyrata [Reaction:R-PVU-1119632] citrate <=> isocitrate - Phaseolus vulgaris [Reaction:R-PTA-1119632] citrate <=> isocitrate - Pinus taeda [Reaction:R-VUN-1119632] citrate <=> isocitrate - Vigna unguiculata [Reaction:R-QLO-1119632] citrate <=> isocitrate - Quercus lobata [Reaction:R-OMI-1119632] citrate <=> isocitrate - Oryza minuta [Reaction:R-LPR-1119632] citrate <=> isocitrate - Lolium perenne [Reaction:R-OSI-1119632] citrate <=> isocitrate - Oryza sativa Indica Group [Reaction:R-TAE-1119632] citrate <=> isocitrate - Triticum aestivum [Reaction:R-VFA-1119632] citrate <=> isocitrate - Vicia faba var. faba [Reaction:R-PDA-1119632] citrate <=> isocitrate - Phoenix dactylifera [Reaction:R-MAC-1119632] citrate <=> isocitrate - Musa acuminata [Reaction:R-AUM-1119632] citrate <=> isocitrate - Aegilops umbellulata [Reaction:R-BOL-1119632] citrate <=> isocitrate - Brassica oleracea [Reaction:R-BVU-1119632] citrate <=> isocitrate - Beta vulgaris [Reaction:R-ATA-1119632] citrate <=> isocitrate - Aegilops tauschii [Reaction:R-PVE-1119632] citrate <=> isocitrate - Pistacia vera [Reaction:R-ETE-1119632] citrate <=> isocitrate - Eragrostis tef [Reaction:R-TDI-1119632] citrate <=> isocitrate - Triticum dicoccoides [Reaction:R-LAN-1119632] citrate <=> isocitrate - Lupinus angustifolius [Reaction:R-JRE-1119632] citrate <=> isocitrate - Juglans regia [Reaction:R-OAU-1119632] citrate <=> isocitrate - Oryza australiensis [Reaction:R-SVI-1119632] citrate <=> isocitrate - Setaria viridis [Reaction:R-AOF-1119632] citrate <=> isocitrate - Asparagus officinalis [Reaction:R-PAB-1119632] citrate <=> isocitrate - Picea abies [Reaction:R-ATR-1119632] citrate <=> isocitrate - Amborella trichopoda [Reaction:R-ORU-1119632] citrate <=> isocitrate - Oryza rufipogon [Reaction:R-HLH-1119632] citrate <=> isocitrate - Humulus lupulus [Reaction:R-CQI-1119632] citrate <=> isocitrate - Chenopodium quinoa [Reaction:R-PPA-1119632] citrate <=> isocitrate - Physcomitrella patens [Reaction:R-RCH-1119632] citrate <=> isocitrate - Rosa chinensis [Reaction:R-OBR-1119632] citrate <=> isocitrate - Oryza brachyantha [Reaction:R-CST-1119632] citrate <=> isocitrate - Camelina sativa [Reaction:R-ACO-1119632] citrate <=> isocitrate - Ananas comosus [Reaction:R-DRO-1119632] citrate <=> isocitrate - Dioscorea rotundata [Reaction:R-CCD-1119632] citrate <=> isocitrate - Cynara cardunculus var. scolymus [Reaction:R-CAR-1119632] citrate <=> isocitrate - Cicer arietinum [Reaction:R-ONI-1119632] citrate <=> isocitrate - Oryza nivara [Reaction:R-LSA-1119632] citrate <=> isocitrate - Lactuca sativa [Reaction:R-COL-1119632] citrate <=> isocitrate - Corchorus olitorius [Reaction:R-SCR-1119632] citrate <=> isocitrate - Secale cereale [Reaction:R-TCA-1119632] citrate <=> isocitrate - Theobroma cacao [Reaction:R-CSA-1119632] citrate <=> isocitrate - Cucumis sativus [Reaction:R-OME-1119632] citrate <=> isocitrate - Oryza meridionalis [Reaction:R-TSP-1119632] citrate <=> isocitrate - Triticum spelta subsp. spelta [Reaction:R-MDO-1119632] citrate <=> isocitrate - Malus domestica [Reaction:R-CML-1119632] citrate <=> isocitrate - Cucumis melo [Reaction:R-GMA-1119632] citrate <=> isocitrate - Glycine max [Reaction:R-SHI-1119632] citrate <=> isocitrate - Salvia hispanica [Reaction:R-SBI-1119632] citrate <=> isocitrate - Sorghum bicolor
output	[SimpleEntity:R-ALL-29938] ISCIT [mitochondrial matrix]
precedingEvent	[Reaction:R-OSA-1120092] oxaloacetate + acetyl-CoA + H2O => citrate + CoA-SH - Oryza sativa
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1119632
summation	[Summation:1173246] Mitochondrial aconitase reversibly converts citrate to isoci...

Referrals

(hasEvent)	[Pathway:R-OSA-1119533] TCA cycle (plant) - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-1120194] isocitrate + NAD+ => 2-oxoglutarate + CO2 + NADH + H+ - Oryza sativa