Plant Reactome Pathway Database - Plant Reactome Pathway Database

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citrate <=> isocitrate

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catalystActivity	[CatalystActivity:10060105] aconitate hydratase activity of ACO [mitochondrial matrix]
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10060092] Elser, Justin, 2025-03-24
dbId	10060107
displayName	citrate <=> isocitrate
eventOf	[Pathway:R-AOF-1119533] TCA cycle (plant) - Asparagus officinalis
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Reaction:R-AOF-1120194] isocitrate + NAD+ => 2-oxoglutarate + CO2 + NADH + H+ - Asparagus officinalis
inferredFrom	[Reaction:R-OSA-1119632] citrate <=> isocitrate - Oryza sativa
input	[SimpleEntity:R-ALL-29654] CIT [mitochondrial matrix]
isInDisease	false
isInferred	true
name	citrate <=> isocitrate Aconitate hydratase
output	[SimpleEntity:R-ALL-29938] ISCIT [mitochondrial matrix]
precedingEvent	[Reaction:R-AOF-1120092] oxaloacetate + acetyl-CoA + H2O => citrate + CoA-SH - Asparagus officinalis
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9659015] Asparagus officinalis
stId	R-AOF-1119632
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

Referrals

(hasEvent)	[Pathway:R-AOF-1119533] TCA cycle (plant) - Asparagus officinalis
(precedingEvent)	[Reaction:R-AOF-1120194] isocitrate + NAD+ => 2-oxoglutarate + CO2 + NADH + H+ - Asparagus officinalis
(inferredTo)	[Reaction:R-OSA-1119632] citrate <=> isocitrate - Oryza sativa