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Sterol biosynthesis

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created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:1133815] RiceCyc:PWY-2541
dbId	1119370
displayName	Sterol biosynthesis
edited	[InstanceEdit:3320173] Beorchia, Dylan, 2012-12-12
eventOf	[Pathway:R-OSA-2744344] Secondary metabolism - Oryza sativa
goBiologicalProcess	[GO_BiologicalProcess:20522] sterol biosynthetic process
hasDiagram	true
hasEvent	[Reaction:R-OSA-1119792] Farnesyl-diphosphate farnesyltransferase - Oryza sativa [Reaction:R-OSA-1120616] presqualene diphosphate+NAD(P)H->squalene+NAD(P)++diphosphate - Oryza sativa [Reaction:R-OSA-1121248] Squalene monooxygenase - Oryza sativa [Reaction:R-OSA-1120561] Cycloartenol synthase - Oryza sativa [Reaction:R-OSA-1121264] S-adenosyl-L-methionine+cycloartenol->S-adenosyl-L-homocysteine+24-methylenecycloartenol - Oryza sativa [Reaction:R-OSA-1120752] a demethylated methyl acceptor+24-methylenecycloartenol+a demethylated methyl acceptor->cycloeucalenol+a methylated methyl acceptor - Oryza sativa [Reaction:R-OSA-1120875] Cycloeucalenol cycloisomerase - Oryza sativa [Reaction:R-OSA-1119691] Sterol 14-demethylase - Oryza sativa [Reaction:R-OSA-1120757] (4alpha)-methyl-(5alpha)-ergosta-8,14,24(28)-trien-3beta-ol+NADPH->4alpha-methylfecosterol+NADP+ - Oryza sativa [Reaction:R-OSA-1120024] 4alpha-methylfecosterol->24-methylenelophenol - Oryza sativa [Reaction:R-OSA-1120096] a demethylated methyl acceptor+24-methylenelophenol+a demethylated methyl acceptor->episterol+a methylated methyl acceptor - Oryza sativa [Reaction:R-OSA-1120440] episterol->5-dehydro episterol - Oryza sativa [Reaction:R-OSA-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Oryza sativa [Reaction:R-OSA-1120782] 24-methylenecholesterol->24-methyldesmosterol - Oryza sativa [Reaction:R-OSA-1121146] 24-methyldesmosterol->campesterol - Oryza sativa [Reaction:R-OSA-1121349] 24-methylenesterol C-methyltransferase - Oryza sativa [Reaction:R-OSA-1121504] a demethylated methyl acceptor+24-ethylidenelophenol+a demethylated methyl acceptor->avenasterol+a methylated methyl acceptor - Oryza sativa [Reaction:R-OSA-1119775] avenasterol->5-dehydroavenasterol - Oryza sativa [Reaction:R-OSA-1121470] 5-dehydroavenasterol+NADPH->isofucosterol+NADP+ - Oryza sativa [Reaction:R-OSA-1120335] isofucosterol->delta24-25-sitosterol - Oryza sativa [Reaction:R-OSA-1120210] delta24-25-sitosterol->sitosterol - Oryza sativa [Reaction:R-OSA-1120944] campesterol+NADP+->crinosterol+NADPH - Oryza sativa [Reaction:R-OSA-1121485] sitosterol+NADP+->stigmasterol+NADPH - Oryza sativa [Reaction:R-OSA-1120122] 24-methyldesmosterol->24-epi-campesterol - Oryza sativa [Reaction:R-OSA-1120314] 24-epi-campesterol+NADP+->brassicasterol+NADPH - Oryza sativa
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	Sterol biosynthesis pathway100451
orthologousEvent	[Pathway:R-OMI-1119370] Sterol biosynthesis - Oryza minuta [Pathway:R-SVI-1119370] Sterol biosynthesis - Setaria viridis [Pathway:R-DCA-1119370] Sterol biosynthesis - Daucus carota [Pathway:R-COL-1119370] Sterol biosynthesis - Corchorus olitorius [Pathway:R-JCU-1119370] Sterol biosynthesis - Jatropha curcas [Pathway:R-TTU-1119370] Sterol biosynthesis - Triticum turgidum [Pathway:R-DRO-1119370] Sterol biosynthesis - Dioscorea rotundata [Pathway:R-CBA-1119370] Sterol biosynthesis - Chara braunii [Pathway:R-CLA-1119370] Sterol biosynthesis - Citrullus lanatus [Pathway:R-OGR-1119370] Sterol biosynthesis - Oryza meyeriana var. granulata [Pathway:R-BNA-1119370] Sterol biosynthesis - Brassica napus [Pathway:R-ATR-1119370] Sterol biosynthesis - Amborella trichopoda [Pathway:R-TCA-1119370] Sterol biosynthesis - Theobroma cacao [Pathway:R-VAN-1119370] Sterol biosynthesis - Vigna angularis [Pathway:R-CQI-1119370] Sterol biosynthesis - Chenopodium quinoa [Pathway:R-BOL-1119370] Sterol biosynthesis - Brassica oleracea [Pathway:R-MGU-1119370] Sterol biosynthesis - Erythranthe guttata [Pathway:R-AOF-1119370] Sterol biosynthesis - Asparagus officinalis [Pathway:R-AHY-1119370] Sterol biosynthesis - Arachis hypogaea [Pathway:R-HVU-1119370] Sterol biosynthesis - Hordeum vulgare [Pathway:R-FCR-1119370] Sterol biosynthesis - Ficus carica [Pathway:R-LAN-1119370] Sterol biosynthesis - Lupinus angustifolius [Pathway:R-ETE-1119370] Sterol biosynthesis - Eragrostis tef [Pathway:R-LPR-1119370] Sterol biosynthesis - Lolium perenne [Pathway:R-ONI-1119370] Sterol biosynthesis - Oryza nivara [Pathway:R-QSU-1119370] Sterol biosynthesis - Quercus suber [Pathway:R-PHH-1119370] Sterol biosynthesis - Panicum hallii var. hallii ("HAL2") [Pathway:R-PSA-1119370] Sterol biosynthesis - Pisum sativum [Pathway:R-SBI-1119370] Sterol biosynthesis - Sorghum bicolor [Pathway:R-CRU-1119370] Sterol biosynthesis - Capsella rubella [Pathway:R-OBA-1119370] Sterol biosynthesis - Oryza barthii [Pathway:R-CCD-1119370] Sterol biosynthesis - Cynara cardunculus var. scolymus [Pathway:R-OME-1119370] Sterol biosynthesis - Oryza meridionalis [Pathway:R-LPE-1119370] Sterol biosynthesis - Leersia perrieri [Pathway:R-CML-1119370] Sterol biosynthesis - Cucumis melo [Pathway:R-OGL-1119370] Sterol biosynthesis - Oryza glaberrima [Pathway:R-TPR-1119370] Sterol biosynthesis - Trifolium pratense [Pathway:R-SMO-1119370] Sterol biosynthesis - Selaginella moellendorffii [Pathway:R-VUN-1119370] Sterol biosynthesis - Vigna unguiculata [Pathway:R-HLH-1119370] Sterol biosynthesis - Humulus lupulus [Pathway:R-STU-1119370] Sterol biosynthesis - Solanum tuberosum [Pathway:R-HAN-1119370] Sterol biosynthesis - Helianthus annuus [Pathway:R-CRE-1119370] Sterol biosynthesis - Chlamydomonas reinhardtii [Pathway:R-RCH-1119370] Sterol biosynthesis - Rosa chinensis [Pathway:R-ALY-1119370] Sterol biosynthesis - Arabidopsis lyrata [Pathway:R-NNU-1119370] Sterol biosynthesis - Nelumbo nucifera [Pathway:R-SCR-1119370] Sterol biosynthesis - Secale cereale [Pathway:R-SIT-1119370] Sterol biosynthesis - Setaria italica [Pathway:R-MAC-1119370] Sterol biosynthesis - Musa acuminata [Pathway:R-CCL-1119370] Sterol biosynthesis - Citrus clementina [Pathway:R-CAR-1119370] Sterol biosynthesis - Cicer arietinum [Pathway:R-CCP-1119370] Sterol biosynthesis - Corchorus capsularis [Pathway:R-TSP-1119370] Sterol biosynthesis - Triticum spelta subsp. spelta [Pathway:R-PVU-1119370] Sterol biosynthesis - Phaseolus vulgaris [Pathway:R-BRA-1119370] Sterol biosynthesis - Brassica rapa [Pathway:R-PTI-1119370] Sterol biosynthesis - Populus trichocarpa [Pathway:R-FEX-1119370] Sterol biosynthesis - Fraxinus excelsior (European ash) [Pathway:R-CSI-1119370] Sterol biosynthesis - Citrus sinensis [Pathway:R-OLU-1119370] Sterol biosynthesis - Ostreococcus lucimarinus [Pathway:R-NAT-1119370] Sterol biosynthesis - Nicotiana attenuata [Pathway:R-BDI-1119370] Sterol biosynthesis - Brachypodium distachyon [Pathway:R-CCA-1119370] Sterol biosynthesis - Cajanus cajan [Pathway:R-ADU-1119370] Sterol biosynthesis - Arachis duranensis [Pathway:R-SPC-1119370] Sterol biosynthesis - Synechocystis sp. PCC 6803 [Pathway:R-OAU-1119370] Sterol biosynthesis - Oryza australiensis [Pathway:R-GRA-1119370] Sterol biosynthesis - Gossypium raimondii [Pathway:R-AUM-1119370] Sterol biosynthesis - Aegilops umbellulata [Pathway:R-GSU-1119370] Sterol biosynthesis - Galdieria sulphuraria [Pathway:R-VRA-1119370] Sterol biosynthesis - Vigna radiata [Pathway:R-GSO-1119370] Sterol biosynthesis - Glycine soja [Pathway:R-QLO-1119370] Sterol biosynthesis - Quercus lobata [Pathway:R-PTA-1119370] Sterol biosynthesis - Pinus taeda [Pathway:R-CSK-1119370] Sterol biosynthesis - Cannabis sativa subsp. indica [Pathway:R-ACO-1119370] Sterol biosynthesis - Ananas comosus [Pathway:R-CST-1119370] Sterol biosynthesis - Camelina sativa [Pathway:R-OOF-1119370] Sterol biosynthesis - Oryza officinalis [Pathway:R-PHA-1119370] Sterol biosynthesis - Panicum hallii ("FIL2") [Pathway:R-CCR-1119370] Sterol biosynthesis - Chondrus crispus [Pathway:R-CSA-1119370] Sterol biosynthesis - Cucumis sativus [Pathway:R-ASA-1119370] Sterol biosynthesis - Avena sativa [Pathway:R-ZMA-1119370] Sterol biosynthesis - Zea mays [Pathway:R-LST-1119370] Sterol biosynthesis - Lathyrus sativus [Pathway:R-OBR-1119370] Sterol biosynthesis - Oryza brachyantha [Pathway:R-PAV-1119370] Sterol biosynthesis - Prunus avium [Pathway:R-MDO-1119370] Sterol biosynthesis - Malus domestica [Pathway:R-CCI-1119370] Sterol biosynthesis - Corymbia citriodora [Pathway:R-OSI-1119370] Sterol biosynthesis - Oryza sativa Indica Group [Pathway:R-BVU-1119370] Sterol biosynthesis - Beta vulgaris [Pathway:R-TAE-1119370] Sterol biosynthesis - Triticum aestivum [Pathway:R-OES-1119370] Sterol biosynthesis - Olea europaea var. sylvestris [Pathway:R-OEU-1119370] Sterol biosynthesis - Olea europaea [Pathway:R-VVN-1119370] Sterol biosynthesis - Vitis vinifera [Pathway:R-PSO-1119370] Sterol biosynthesis - Papaver somniferum [Pathway:R-OGU-1119370] Sterol biosynthesis - Oryza glumaepatula [Pathway:R-GMA-1119370] Sterol biosynthesis - Glycine max [Pathway:R-PVE-1119370] Sterol biosynthesis - Pistacia vera [Pathway:R-MTR-1119370] Sterol biosynthesis - Medicago truncatula [Pathway:R-MPO-1119370] Sterol biosynthesis - Marchantia polymorpha [Pathway:R-ZMY-1119370] Sterol biosynthesis - Zea mays ver5 [Pathway:R-DEX-1119370] Sterol biosynthesis - Digitaria exilis [Pathway:R-AHA-1119370] Sterol biosynthesis - Arabidopsis halleri [Pathway:R-SSP-1119370] Sterol biosynthesis - Saccharum spontaneum [Pathway:R-TDI-1119370] Sterol biosynthesis - Triticum dicoccoides [Pathway:R-ORU-1119370] Sterol biosynthesis - Oryza rufipogon [Pathway:R-MES-1119370] Sterol biosynthesis - Manihot esculenta [Pathway:R-CCN-1119370] Sterol biosynthesis - Coffea canephora [Pathway:R-PDA-1119370] Sterol biosynthesis - Phoenix dactylifera [Pathway:R-OLO-1119370] Sterol biosynthesis - Oryza longistaminata [Pathway:R-ITR-1119370] Sterol biosynthesis - Ipomoea triloba [Pathway:R-ZJA-1119370] Sterol biosynthesis - Zoysia japonica [Pathway:R-ECG-1119370] Sterol biosynthesis - Echinochloa crus-galli [Pathway:R-AIP-1119370] Sterol biosynthesis - Arachis ipaensis [Pathway:R-CME-1119370] Sterol biosynthesis - Cyanidioschyzon merolae [Pathway:R-HLP-1119370] Sterol biosynthesis - Humulus lupulus var. lupulus [Pathway:R-FVE-1119370] Sterol biosynthesis - Fragaria vesca [Pathway:R-NCO-1119370] Sterol biosynthesis - Nymphaea colorata [Pathway:R-JRE-1119370] Sterol biosynthesis - Juglans regia [Pathway:R-OPU-1119370] Sterol biosynthesis - Oryza punctata [Pathway:R-EGR-1119370] Sterol biosynthesis - Eucalyptus grandis [Pathway:R-TUR-1119370] Sterol biosynthesis - Triticum urartu [Pathway:R-BJU-1119370] Sterol biosynthesis - Brassica juncea [Pathway:R-CSC-1119370] Sterol biosynthesis - Cannabis sativa [Pathway:R-VFA-1119370] Sterol biosynthesis - Vicia faba var. faba [Pathway:R-ACH-1119370] Sterol biosynthesis - Actinidia chinensis [Pathway:R-TTI-1119370] Sterol biosynthesis - Triticum timopheevii subsp. timopheevii [Pathway:R-CAN-1119370] Sterol biosynthesis - Capsicum annuum [Pathway:R-PAB-1119370] Sterol biosynthesis - Picea abies [Pathway:R-SHI-1119370] Sterol biosynthesis - Salvia hispanica [Pathway:R-SIN-1119370] Sterol biosynthesis - Sesamum indicum [Pathway:R-PPA-1119370] Sterol biosynthesis - Physcomitrella patens [Pathway:R-PPE-1119370] Sterol biosynthesis - Prunus persica [Pathway:R-SLY-1119370] Sterol biosynthesis - Solanum lycopersicum [Pathway:R-ATA-1119370] Sterol biosynthesis - Aegilops tauschii [Pathway:R-LSA-1119370] Sterol biosynthesis - Lactuca sativa [Pathway:R-PED-1119370] Sterol biosynthesis - Phyllostachys edulis [Pathway:R-ATH-1119370] Sterol biosynthesis - Arabidopsis thaliana [Pathway:R-OKA-1119370] Sterol biosynthesis - Oryza sativa aus subgroup [Pathway:R-ECU-1119370] Sterol biosynthesis - Eragrostis curvula
schemaClass	Pathway
species	[Species:186860] Oryza sativa
stId	R-OSA-1119370
summation	[Summation:3320174] sterol biosynthesis [Summation:2850146] Developed by Gramene.org

Referrals

(hasEvent)

[Pathway:R-OSA-2744344] Secondary metabolism - Oryza sativa

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