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5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+

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catalystActivity	[CatalystActivity:1118586] 7-dehydrocholesterol reductase activity of delta14-sterol reductase (LOC_OS02G26650.1) [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:1154373] EC-NUMBER:1.3.1.21 [DatabaseIdentifier:1135881] RiceCyc:RXN-707
dbId	1121246
displayName	5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+
eventOf	[Pathway:R-OSA-1119370] Sterol biosynthesis - Oryza sativa
followingEvent	[Reaction:R-OSA-1120782] 24-methylenecholesterol->24-methyldesmosterol - Oryza sativa
input	[SimpleEntity:R-ALL-1131139] 5-dehydro episterol [cytosol] [SimpleEntity:R-ALL-29364] NADPH [cytosol]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11529250] Elser, Justin, 2025-03-27
name	5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ RXN-707 biochemicalReaction80921
orthologousEvent	[Reaction:R-CCL-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Citrus clementina [Reaction:R-PPE-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Prunus persica [Reaction:R-NCO-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Nymphaea colorata [Reaction:R-TCA-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Theobroma cacao [Reaction:R-SIN-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Sesamum indicum [Reaction:R-GRA-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Gossypium raimondii [Reaction:R-MTR-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Medicago truncatula [Reaction:R-PSO-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Papaver somniferum [Reaction:R-NAT-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Nicotiana attenuata [Reaction:R-ORU-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Oryza rufipogon [Reaction:R-OLU-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Ostreococcus lucimarinus [Reaction:R-ITR-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Ipomoea triloba [Reaction:R-CCD-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Cynara cardunculus var. scolymus [Reaction:R-MES-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Manihot esculenta [Reaction:R-TPR-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Trifolium pratense [Reaction:R-VVN-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Vitis vinifera [Reaction:R-ATR-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Amborella trichopoda [Reaction:R-OBA-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Oryza barthii [Reaction:R-CAN-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Capsicum annuum [Reaction:R-ALY-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Arabidopsis lyrata [Reaction:R-TTU-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Triticum turgidum [Reaction:R-MDO-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Malus domestica [Reaction:R-LST-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Lathyrus sativus [Reaction:R-OME-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Oryza meridionalis [Reaction:R-SBI-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Sorghum bicolor [Reaction:R-ECU-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Eragrostis curvula [Reaction:R-OPU-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Oryza punctata [Reaction:R-SCR-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Secale cereale [Reaction:R-AHA-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Arabidopsis halleri [Reaction:R-TSP-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Triticum spelta subsp. spelta [Reaction:R-FEX-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Fraxinus excelsior (European ash) [Reaction:R-SIT-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Setaria italica [Reaction:R-AUM-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Aegilops umbellulata [Reaction:R-GSO-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Glycine soja [Reaction:R-TDI-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Triticum dicoccoides [Reaction:R-TTI-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Triticum timopheevii subsp. timopheevii [Reaction:R-OGU-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Oryza glumaepatula [Reaction:R-PSA-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Pisum sativum [Reaction:R-SSP-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Saccharum spontaneum [Reaction:R-CSC-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Cannabis sativa [Reaction:R-BJU-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Brassica juncea [Reaction:R-CSA-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Cucumis sativus [Reaction:R-CCA-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Cajanus cajan [Reaction:R-PHA-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Panicum hallii ("FIL2") [Reaction:R-LPR-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Lolium perenne [Reaction:R-MAC-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Musa acuminata [Reaction:R-AOF-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Asparagus officinalis [Reaction:R-PVE-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Pistacia vera [Reaction:R-CRE-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Chlamydomonas reinhardtii [Reaction:R-FCR-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Ficus carica [Reaction:R-AHY-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Arachis hypogaea [Reaction:R-ECG-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Echinochloa crus-galli [Reaction:R-OBR-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Oryza brachyantha [Reaction:R-LPE-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Leersia perrieri [Reaction:R-PHH-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Panicum hallii var. hallii ("HAL2") [Reaction:R-BOL-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Brassica oleracea [Reaction:R-BRA-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Brassica rapa [Reaction:R-OEU-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Olea europaea [Reaction:R-SMO-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Selaginella moellendorffii [Reaction:R-DCA-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Daucus carota [Reaction:R-SLY-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Solanum lycopersicum [Reaction:R-OSI-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Oryza sativa Indica Group [Reaction:R-BVU-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Beta vulgaris [Reaction:R-CML-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Cucumis melo [Reaction:R-TUR-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Triticum urartu [Reaction:R-OGL-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Oryza glaberrima [Reaction:R-CCI-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Corymbia citriodora [Reaction:R-DEX-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Digitaria exilis [Reaction:R-HVU-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Hordeum vulgare [Reaction:R-MPO-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Marchantia polymorpha [Reaction:R-VUN-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Vigna unguiculata [Reaction:R-ATH-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Arabidopsis thaliana [Reaction:R-OES-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Olea europaea var. sylvestris [Reaction:R-LAN-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Lupinus angustifolius [Reaction:R-QLO-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Quercus lobata [Reaction:R-ZMY-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Zea mays ver5 [Reaction:R-HAN-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Helianthus annuus [Reaction:R-OLO-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Oryza longistaminata [Reaction:R-ACH-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Actinidia chinensis [Reaction:R-CCN-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Coffea canephora [Reaction:R-GMA-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Glycine max [Reaction:R-BDI-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Brachypodium distachyon [Reaction:R-ACO-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Ananas comosus [Reaction:R-RCH-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Rosa chinensis [Reaction:R-VFA-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Vicia faba var. faba [Reaction:R-ASA-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Avena sativa [Reaction:R-PVU-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Phaseolus vulgaris [Reaction:R-CST-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Camelina sativa [Reaction:R-PTI-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Populus trichocarpa [Reaction:R-LSA-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Lactuca sativa [Reaction:R-ETE-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Eragrostis tef [Reaction:R-EGR-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Eucalyptus grandis [Reaction:R-JRE-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Juglans regia [Reaction:R-ZMA-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Zea mays [Reaction:R-CCP-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Corchorus capsularis [Reaction:R-ONI-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Oryza nivara [Reaction:R-VRA-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Vigna radiata [Reaction:R-PPA-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Physcomitrella patens [Reaction:R-CQI-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Chenopodium quinoa [Reaction:R-VAN-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Vigna angularis [Reaction:R-ATA-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Aegilops tauschii [Reaction:R-TAE-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Triticum aestivum [Reaction:R-SVI-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Setaria viridis [Reaction:R-STU-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Solanum tuberosum [Reaction:R-DRO-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Dioscorea rotundata [Reaction:R-QSU-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Quercus suber [Reaction:R-BNA-1121246] 5-dehydro episterol+NADPH->24-methylenecholesterol+NADP+ - Brassica napus
output	[SimpleEntity:R-ALL-1132128] 24-methylenecholesterol [cytosol] [SimpleEntity:R-ALL-29366] NADP+ [cytosol]
precedingEvent	[Reaction:R-OSA-1120440] episterol->5-dehydro episterol - Oryza sativa
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1121246
summation	[Summation:3320160] 5-dehydro episterol is converted into 24-methylenecholestero...

Referrals

(hasEvent)	[Pathway:R-OSA-1119370] Sterol biosynthesis - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-1120782] 24-methylenecholesterol->24-methyldesmosterol - Oryza sativa