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Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde

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catalystActivity	[CatalystActivity:9611872] 3-hydroxyisobutyrate dehydrogenase activity of 3-hydroxyisobutyrate dehydrogenase [mitochondrial inner membrane]
compartment	[Compartment:70616] mitochondrial inner membrane [Compartment:5460] mitochondrial matrix
created	[InstanceEdit:9611891] Gupta, Parul, 2018-06-21
crossReference	[DatabaseIdentifier:26545] EC:1.1.1.31
dbId	9611895
displayName	Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde
eventOf	[Pathway:R-OSA-1119479] Valine degradation - Oryza sativa
followingEvent	[Reaction:R-OSA-9611884] Conversion of methylmalonate-semialdehyde to Propionyl-CoA - Oryza sativa
input	[SimpleEntity:R-ALL-9611886] 3-hydroxy-isobutyrate [mitochondrial matrix] [SimpleEntity:R-ALL-113526] NAD+ [mitochondrial matrix]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde
orthologousEvent	[Reaction:R-SHI-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Salvia hispanica [Reaction:R-ITR-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Ipomoea triloba [Reaction:R-JRE-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Juglans regia [Reaction:R-TDI-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Triticum dicoccoides [Reaction:R-PHH-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Panicum hallii var. hallii ("HAL2") [Reaction:R-PAB-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Picea abies [Reaction:R-ASA-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Avena sativa [Reaction:R-DEX-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Digitaria exilis [Reaction:R-ETE-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Eragrostis tef [Reaction:R-CSK-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Cannabis sativa subsp. indica [Reaction:R-JCU-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Jatropha curcas [Reaction:R-OBA-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Oryza barthii [Reaction:R-BRA-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Brassica rapa [Reaction:R-TCA-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Theobroma cacao [Reaction:R-FVE-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Fragaria vesca [Reaction:R-HLP-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Humulus lupulus var. lupulus [Reaction:R-SIT-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Setaria italica [Reaction:R-ADU-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Arachis duranensis [Reaction:R-RCH-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Rosa chinensis [Reaction:R-CCA-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Cajanus cajan [Reaction:R-LSA-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Lactuca sativa [Reaction:R-NNU-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Nelumbo nucifera [Reaction:R-VRA-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Vigna radiata [Reaction:R-BVU-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Beta vulgaris [Reaction:R-GSU-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Galdieria sulphuraria [Reaction:R-AHY-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Arachis hypogaea [Reaction:R-CSI-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Citrus sinensis [Reaction:R-MTR-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Medicago truncatula [Reaction:R-OBR-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Oryza brachyantha [Reaction:R-QLO-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Quercus lobata [Reaction:R-CST-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Camelina sativa [Reaction:R-SLY-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Solanum lycopersicum [Reaction:R-OSI-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Oryza sativa Indica Group [Reaction:R-ONI-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Oryza nivara [Reaction:R-VVN-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Vitis vinifera [Reaction:R-ZMY-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Zea mays ver5 [Reaction:R-TTU-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Triticum turgidum [Reaction:R-ACO-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Ananas comosus [Reaction:R-ATA-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Aegilops tauschii [Reaction:R-AIP-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Arachis ipaensis [Reaction:R-MDO-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Malus domestica [Reaction:R-ATR-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Amborella trichopoda [Reaction:R-ZMA-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Zea mays [Reaction:R-PHA-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Panicum hallii ("FIL2") [Reaction:R-OGR-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Oryza meyeriana var. granulata [Reaction:R-CAN-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Capsicum annuum [Reaction:R-TSP-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Triticum spelta subsp. spelta [Reaction:R-MES-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Manihot esculenta [Reaction:R-CCL-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Citrus clementina [Reaction:R-SCR-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Secale cereale [Reaction:R-LPR-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Lolium perenne [Reaction:R-GMA-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Glycine max [Reaction:R-CML-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Cucumis melo [Reaction:R-HVU-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Hordeum vulgare [Reaction:R-DRO-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Dioscorea rotundata [Reaction:R-MPO-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Marchantia polymorpha [Reaction:R-OGU-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Oryza glumaepatula [Reaction:R-BDI-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Brachypodium distachyon [Reaction:R-MGU-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Erythranthe guttata [Reaction:R-VUN-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Vigna unguiculata [Reaction:R-ZJA-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Zoysia japonica [Reaction:R-HLH-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Humulus lupulus [Reaction:R-FEX-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Fraxinus excelsior (European ash) [Reaction:R-NCO-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Nymphaea colorata [Reaction:R-OMI-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Oryza minuta [Reaction:R-CSA-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Cucumis sativus [Reaction:R-NAT-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Nicotiana attenuata [Reaction:R-AUM-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Aegilops umbellulata [Reaction:R-PTI-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Populus trichocarpa [Reaction:R-BOL-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Brassica oleracea [Reaction:R-CQI-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Chenopodium quinoa [Reaction:R-BJU-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Brassica juncea [Reaction:R-ECG-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Echinochloa crus-galli [Reaction:R-QSU-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Quercus suber [Reaction:R-SVI-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Setaria viridis [Reaction:R-CRU-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Capsella rubella [Reaction:R-MAC-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Musa acuminata [Reaction:R-PVU-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Phaseolus vulgaris [Reaction:R-FCR-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Ficus carica [Reaction:R-TPR-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Trifolium pratense [Reaction:R-GRA-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Gossypium raimondii [Reaction:R-HAN-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Helianthus annuus [Reaction:R-CCD-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Cynara cardunculus var. scolymus [Reaction:R-CCI-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Corymbia citriodora [Reaction:R-COL-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Corchorus olitorius [Reaction:R-AHA-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Arabidopsis halleri [Reaction:R-CCP-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Corchorus capsularis [Reaction:R-PSA-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Pisum sativum [Reaction:R-LAN-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Lupinus angustifolius [Reaction:R-VFA-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Vicia faba var. faba [Reaction:R-TTI-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Triticum timopheevii subsp. timopheevii [Reaction:R-EGR-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Eucalyptus grandis [Reaction:R-SSP-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Saccharum spontaneum [Reaction:R-CCN-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Coffea canephora [Reaction:R-ACH-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Actinidia chinensis [Reaction:R-OPU-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Oryza punctata [Reaction:R-LPE-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Leersia perrieri [Reaction:R-TUR-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Triticum urartu [Reaction:R-BNA-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Brassica napus [Reaction:R-PVE-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Pistacia vera [Reaction:R-OAU-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Oryza australiensis [Reaction:R-OEU-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Olea europaea [Reaction:R-CAR-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Cicer arietinum [Reaction:R-PPE-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Prunus persica [Reaction:R-CLA-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Citrullus lanatus [Reaction:R-LST-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Lathyrus sativus [Reaction:R-CRE-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Chlamydomonas reinhardtii [Reaction:R-OES-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Olea europaea var. sylvestris [Reaction:R-ALY-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Arabidopsis lyrata [Reaction:R-OOF-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Oryza officinalis [Reaction:R-TAE-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Triticum aestivum [Reaction:R-ATH-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Arabidopsis thaliana [Reaction:R-PPA-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Physcomitrella patens [Reaction:R-ORU-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Oryza rufipogon [Reaction:R-GSO-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Glycine soja [Reaction:R-DCA-9611895] Conversion of 3-hydroxy-isobutyrate to methylmalonate-semialdehyde - Daucus carota
output	[SimpleEntity:R-ALL-9611873] methylmalonate-semialdehyde [mitochondrial matrix] [SimpleEntity:R-ALL-29362] NADH [mitochondrial matrix]
precedingEvent	[Reaction:R-OSA-9611885] Conversion of 3-hydroxy-isobutyryl-CoA to 3-hydroxy-isobutyrate - Oryza sativa
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-9611895

Referrals

(hasEvent)	[Pathway:R-OSA-1119479] Valine degradation - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-9611884] Conversion of methylmalonate-semialdehyde to Propionyl-CoA - Oryza sativa

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