Plant Reactome Pathway Database - Plant Reactome Pathway Database

catalystActivity	[CatalystActivity:1118815] ligase activity of 4-coumarate--CoA ligase [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:28118] EC:6.2.1.12 [DatabaseIdentifier:1153927] RiceCyc:4-COUMARATE--COA-LIGASE-RXN
dbId	1121022
displayName	4-coumarate--CoA ligase
eventOf	[Pathway:R-OSA-1119316] Phenylpropanoid biosynthesis - Oryza sativa [Pathway:R-OSA-1119531] Flavonoid biosynthesis - Oryza sativa
followingEvent	[Reaction:R-OSA-1120772] 4-coumaroyl-CoA+quinate+coumaroyl-CoA->4-coumaroylquinate+coenzyme A - Oryza sativa [Reaction:R-OSA-1121060] 4-coumaroyl-CoA+shikimate+coumaroyl-CoA->4-coumaroylshikimate+coenzyme A - Oryza sativa [Reaction:R-OSA-1119714] 4-coumaroyl-CoA+coumaroyl-CoA+malonyl-CoA+NADPH->isoliquiritigenin+coenzyme A+CO2+NADP++H2O - Oryza sativa [Reaction:R-OSA-1120784] Naringenin-chalcone synthase - Oryza sativa [Reaction:R-OSA-1120189] 4-coumaroyl-CoA+coumaroyl-CoA+NADPH->coumaraldehyde+NADP++coenzyme A - Oryza sativa
input	[SimpleEntity:R-ALL-1130542] 4-coumarate [cytosol] [SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-76194] CoA-SH [cytosol]
isInDisease	false
isInferred	false
modified	[InstanceEdit:9939619] Elser, Justin, 2025-03-06
name	4-coumarate--CoA ligase 4-coumaryl-CoA synthetase biochemicalReaction7413
output	[SimpleEntity:R-ALL-1130740] 4-coumaroyl-CoA [cytosol] [SimpleEntity:R-ALL-76577] AMP [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol]
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1121022
summation	[Summation:2878084] 4-coumarate is converted into 4-coumaroyl-CoA by enzymatic a...

4-coumarate--CoA ligase

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