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Naringenin-chalcone synthase

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catalystActivity	[CatalystActivity:1118421] naringenin-chalcone synthase activity of chalcone synthase [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:27039] EC:2.3.1.74 [DatabaseIdentifier:1132735] RiceCyc:NARINGENIN-CHALCONE-SYNTHASE-RXN
dbId	1120784
displayName	Naringenin-chalcone synthase
eventOf	[Pathway:R-OSA-1119531] Flavonoid biosynthesis - Oryza sativa
followingEvent	[Reaction:R-OSA-1120799] Chalcone isomerase - Oryza sativa
input	[SimpleEntity:R-ALL-1130740] 4-coumaroyl-CoA [cytosol] [SimpleEntity:R-ALL-1131945] coumaroyl-CoA [cytosol] 3 × [SimpleEntity:R-ALL-29508] Mal-CoA [cytosol]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	Naringenin-chalcone synthase 6'-deoxychalcone synthase Flavonone synthase Chalcone synthase biochemicalReaction75344
orthologousEvent	[Reaction:R-TPR-1120784] Naringenin-chalcone synthase - Trifolium pratense [Reaction:R-ACH-1120784] Naringenin-chalcone synthase - Actinidia chinensis [Reaction:R-CCI-1120784] Naringenin-chalcone synthase - Corymbia citriodora [Reaction:R-VFA-1120784] Naringenin-chalcone synthase - Vicia faba var. faba [Reaction:R-TDI-1120784] Naringenin-chalcone synthase - Triticum dicoccoides [Reaction:R-OKA-1120784] Naringenin-chalcone synthase - Oryza sativa aus subgroup [Reaction:R-VAN-1120784] Naringenin-chalcone synthase - Vigna angularis [Reaction:R-ITR-1120784] Naringenin-chalcone synthase - Ipomoea triloba [Reaction:R-LPR-1120784] Naringenin-chalcone synthase - Lolium perenne [Reaction:R-JRE-1120784] Naringenin-chalcone synthase - Juglans regia [Reaction:R-GSO-1120784] Naringenin-chalcone synthase - Glycine soja [Reaction:R-TCA-1120784] Naringenin-chalcone synthase - Theobroma cacao [Reaction:R-SVI-1120784] Naringenin-chalcone synthase - Setaria viridis [Reaction:R-AOF-1120784] Naringenin-chalcone synthase - Asparagus officinalis [Reaction:R-BDI-1120784] Naringenin-chalcone synthase - Brachypodium distachyon [Reaction:R-AHY-1120784] Naringenin-chalcone synthase - Arachis hypogaea [Reaction:R-QLO-1120784] Naringenin-chalcone synthase - Quercus lobata [Reaction:R-MPO-1120784] Naringenin-chalcone synthase - Marchantia polymorpha [Reaction:R-CCA-1120784] Naringenin-chalcone synthase - Cajanus cajan [Reaction:R-MES-1120784] Naringenin-chalcone synthase - Manihot esculenta [Reaction:R-PVE-1120784] Naringenin-chalcone synthase - Pistacia vera [Reaction:R-OAU-1120784] Naringenin-chalcone synthase - Oryza australiensis [Reaction:R-GMA-1120784] Naringenin-chalcone synthase - Glycine max [Reaction:R-CCP-1120784] Naringenin-chalcone synthase - Corchorus capsularis [Reaction:R-PAB-1120784] Naringenin-chalcone synthase - Picea abies [Reaction:R-PVU-1120784] Naringenin-chalcone synthase - Phaseolus vulgaris [Reaction:R-FCR-1120784] Naringenin-chalcone synthase - Ficus carica [Reaction:R-CCL-1120784] Naringenin-chalcone synthase - Citrus clementina [Reaction:R-AUM-1120784] Naringenin-chalcone synthase - Aegilops umbellulata [Reaction:R-HVU-1120784] Naringenin-chalcone synthase - Hordeum vulgare [Reaction:R-TTU-1120784] Naringenin-chalcone synthase - Triticum turgidum [Reaction:R-OSI-1120784] Naringenin-chalcone synthase - Oryza sativa Indica Group [Reaction:R-PDA-1120784] Naringenin-chalcone synthase - Phoenix dactylifera [Reaction:R-VRA-1120784] Naringenin-chalcone synthase - Vigna radiata [Reaction:R-SMO-1120784] Naringenin-chalcone synthase - Selaginella moellendorffii [Reaction:R-ORU-1120784] Naringenin-chalcone synthase - Oryza rufipogon [Reaction:R-OPU-1120784] Naringenin-chalcone synthase - Oryza punctata [Reaction:R-QSU-1120784] Naringenin-chalcone synthase - Quercus suber [Reaction:R-CAR-1120784] Naringenin-chalcone synthase - Cicer arietinum [Reaction:R-PHH-1120784] Naringenin-chalcone synthase - Panicum hallii var. hallii ("HAL2") [Reaction:R-CCD-1120784] Naringenin-chalcone synthase - Cynara cardunculus var. scolymus [Reaction:R-PTI-1120784] Naringenin-chalcone synthase - Populus trichocarpa [Reaction:R-CLA-1120784] Naringenin-chalcone synthase - Citrullus lanatus [Reaction:R-ADU-1120784] Naringenin-chalcone synthase - Arachis duranensis [Reaction:R-NNU-1120784] Naringenin-chalcone synthase - Nelumbo nucifera [Reaction:R-PSO-1120784] Naringenin-chalcone synthase - Papaver somniferum [Reaction:R-CSK-1120784] Naringenin-chalcone synthase - Cannabis sativa subsp. indica [Reaction:R-SIT-1120784] Naringenin-chalcone synthase - Setaria italica [Reaction:R-ZJA-1120784] Naringenin-chalcone synthase - Zoysia japonica [Reaction:R-COL-1120784] Naringenin-chalcone synthase - Corchorus olitorius [Reaction:R-ONI-1120784] Naringenin-chalcone synthase - Oryza nivara [Reaction:R-ATA-1120784] Naringenin-chalcone synthase - Aegilops tauschii [Reaction:R-LST-1120784] Naringenin-chalcone synthase - Lathyrus sativus [Reaction:R-PTA-1120784] Naringenin-chalcone synthase - Pinus taeda [Reaction:R-OLO-1120784] Naringenin-chalcone synthase - Oryza longistaminata [Reaction:R-ECG-1120784] Naringenin-chalcone synthase - Echinochloa crus-galli [Reaction:R-VVN-1120784] Naringenin-chalcone synthase - Vitis vinifera [Reaction:R-PED-1120784] Naringenin-chalcone synthase - Phyllostachys edulis [Reaction:R-DEX-1120784] Naringenin-chalcone synthase - Digitaria exilis [Reaction:R-AIP-1120784] Naringenin-chalcone synthase - Arachis ipaensis [Reaction:R-CSA-1120784] Naringenin-chalcone synthase - Cucumis sativus [Reaction:R-SCR-1120784] Naringenin-chalcone synthase - Secale cereale [Reaction:R-OOF-1120784] Naringenin-chalcone synthase - Oryza officinalis [Reaction:R-HLP-1120784] Naringenin-chalcone synthase - Humulus lupulus var. lupulus [Reaction:R-CML-1120784] Naringenin-chalcone synthase - Cucumis melo [Reaction:R-ACO-1120784] Naringenin-chalcone synthase - Ananas comosus [Reaction:R-LPE-1120784] Naringenin-chalcone synthase - Leersia perrieri [Reaction:R-TAE-1120784] Naringenin-chalcone synthase - Triticum aestivum [Reaction:R-MGU-1120784] Naringenin-chalcone synthase - Erythranthe guttata [Reaction:R-ETE-1120784] Naringenin-chalcone synthase - Eragrostis tef [Reaction:R-SHI-1120784] Naringenin-chalcone synthase - Salvia hispanica [Reaction:R-OBR-1120784] Naringenin-chalcone synthase - Oryza brachyantha [Reaction:R-SSP-1120784] Naringenin-chalcone synthase - Saccharum spontaneum [Reaction:R-CSI-1120784] Naringenin-chalcone synthase - Citrus sinensis [Reaction:R-LSA-1120784] Naringenin-chalcone synthase - Lactuca sativa [Reaction:R-DCA-1120784] Naringenin-chalcone synthase - Daucus carota [Reaction:R-OBA-1120784] Naringenin-chalcone synthase - Oryza barthii [Reaction:R-CQI-1120784] Naringenin-chalcone synthase - Chenopodium quinoa [Reaction:R-CRU-1120784] Naringenin-chalcone synthase - Capsella rubella [Reaction:R-MAC-1120784] Naringenin-chalcone synthase - Musa acuminata [Reaction:R-OGL-1120784] Naringenin-chalcone synthase - Oryza glaberrima [Reaction:R-MTR-1120784] Naringenin-chalcone synthase - Medicago truncatula [Reaction:R-HLH-1120784] Naringenin-chalcone synthase - Humulus lupulus [Reaction:R-VUN-1120784] Naringenin-chalcone synthase - Vigna unguiculata [Reaction:R-BVU-1120784] Naringenin-chalcone synthase - Beta vulgaris [Reaction:R-EGR-1120784] Naringenin-chalcone synthase - Eucalyptus grandis [Reaction:R-TUR-1120784] Naringenin-chalcone synthase - Triticum urartu [Reaction:R-LAN-1120784] Naringenin-chalcone synthase - Lupinus angustifolius [Reaction:R-JCU-1120784] Naringenin-chalcone synthase - Jatropha curcas [Reaction:R-PPA-1120784] Naringenin-chalcone synthase - Physcomitrella patens [Reaction:R-ASA-1120784] Naringenin-chalcone synthase - Avena sativa [Reaction:R-TTI-1120784] Naringenin-chalcone synthase - Triticum timopheevii subsp. timopheevii [Reaction:R-SBI-1120784] Naringenin-chalcone synthase - Sorghum bicolor [Reaction:R-OGR-1120784] Naringenin-chalcone synthase - Oryza meyeriana var. granulata [Reaction:R-OMI-1120784] Naringenin-chalcone synthase - Oryza minuta [Reaction:R-PHA-1120784] Naringenin-chalcone synthase - Panicum hallii ("FIL2") [Reaction:R-HAN-1120784] Naringenin-chalcone synthase - Helianthus annuus [Reaction:R-FVE-1120784] Naringenin-chalcone synthase - Fragaria vesca [Reaction:R-TSP-1120784] Naringenin-chalcone synthase - Triticum spelta subsp. spelta [Reaction:R-OGU-1120784] Naringenin-chalcone synthase - Oryza glumaepatula [Reaction:R-ECU-1120784] Naringenin-chalcone synthase - Eragrostis curvula [Reaction:R-GRA-1120784] Naringenin-chalcone synthase - Gossypium raimondii
output	[SimpleEntity:R-ALL-1132338] apigenin [cytosol] 3 × [SimpleEntity:R-ALL-113528] CO2 [cytosol] 4 × [SimpleEntity:R-ALL-76194] CoA-SH [cytosol]
precedingEvent	[Reaction:R-OSA-1121022] 4-coumarate--CoA ligase - Oryza sativa
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1120784
summation	[Summation:2878079] 4-coumaroyl-CoA is converted into naringenin chalcone by enz...

Referrals

(hasEvent)	[Pathway:R-OSA-1119531] Flavonoid biosynthesis - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-1120799] Chalcone isomerase - Oryza sativa