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2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2

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authored	[InstanceEdit:8933720] Gupta, Parul, 2016-08-08
catalystActivity	[CatalystActivity:8986574] oxoglutarate dehydrogenase (succinyl-transferring) activity of 2-oxoglutarate dehydrogenase E1 component [mitochondrial matrix]
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:8986575] Gupta, Parul, 2017-04-28
dbId	8986551
displayName	2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2
eventOf	[Pathway:R-OSA-1119365] Lysine degradation II - Oryza sativa
followingEvent	[Reaction:R-OSA-8986553] S-glutaryldihydrolipoamide + succinyl-CoA ----> Glutaryl-CoA + S-succinyldihydrolipoamide - Oryza sativa
input	[SimpleEntity:R-ALL-70951] 2-OA [mitochondrial matrix] [SimpleEntity:R-ALL-29824] LIPAM [mitochondrial matrix]
isChimeric	false
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2
orthologousEvent	[Reaction:R-HAN-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Helianthus annuus [Reaction:R-OLU-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Ostreococcus lucimarinus [Reaction:R-CSC-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Cannabis sativa [Reaction:R-OKA-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Oryza sativa aus subgroup [Reaction:R-CCL-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Citrus clementina [Reaction:R-TCA-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Theobroma cacao [Reaction:R-OBR-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Oryza brachyantha [Reaction:R-OPU-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Oryza punctata [Reaction:R-MGU-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Erythranthe guttata [Reaction:R-MAC-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Musa acuminata [Reaction:R-CLA-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Citrullus lanatus [Reaction:R-OMI-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Oryza minuta [Reaction:R-PAV-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Prunus avium [Reaction:R-EGR-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Eucalyptus grandis [Reaction:R-ADU-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Arachis duranensis [Reaction:R-PTA-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Pinus taeda [Reaction:R-VRA-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Vigna radiata [Reaction:R-ONI-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Oryza nivara [Reaction:R-ALY-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Arabidopsis lyrata [Reaction:R-ZMY-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Zea mays ver5 [Reaction:R-VAN-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Vigna angularis [Reaction:R-DRO-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Dioscorea rotundata [Reaction:R-AIP-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Arachis ipaensis [Reaction:R-BOL-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Brassica oleracea [Reaction:R-GMA-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Glycine max [Reaction:R-ECU-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Eragrostis curvula [Reaction:R-SBI-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Sorghum bicolor [Reaction:R-DCA-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Daucus carota [Reaction:R-SCR-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Secale cereale [Reaction:R-CCI-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Corymbia citriodora [Reaction:R-OAU-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Oryza australiensis [Reaction:R-VFA-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Vicia faba var. faba [Reaction:R-NNU-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Nelumbo nucifera [Reaction:R-VUN-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Vigna unguiculata [Reaction:R-CSI-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Citrus sinensis [Reaction:R-TSP-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Triticum spelta subsp. spelta [Reaction:R-ACH-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Actinidia chinensis [Reaction:R-SSP-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Saccharum spontaneum [Reaction:R-MTR-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Medicago truncatula [Reaction:R-ATH-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Arabidopsis thaliana [Reaction:R-QLO-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Quercus lobata [Reaction:R-ZJA-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Zoysia japonica [Reaction:R-BVU-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Beta vulgaris [Reaction:R-CCD-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Cynara cardunculus var. scolymus [Reaction:R-PHH-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Panicum hallii var. hallii ("HAL2") [Reaction:R-ETE-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Eragrostis tef [Reaction:R-HLP-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Humulus lupulus var. lupulus [Reaction:R-JCU-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Jatropha curcas [Reaction:R-RCH-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Rosa chinensis [Reaction:R-PTI-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Populus trichocarpa [Reaction:R-ATR-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Amborella trichopoda [Reaction:R-BJU-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Brassica juncea [Reaction:R-AHA-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Arabidopsis halleri [Reaction:R-OEU-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Olea europaea [Reaction:R-ZMA-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Zea mays [Reaction:R-OLO-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Oryza longistaminata [Reaction:R-CQI-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Chenopodium quinoa [Reaction:R-STU-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Solanum tuberosum [Reaction:R-HVU-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Hordeum vulgare [Reaction:R-LPE-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Leersia perrieri [Reaction:R-LSA-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Lactuca sativa [Reaction:R-OES-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Olea europaea var. sylvestris [Reaction:R-PPA-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Physcomitrella patens [Reaction:R-PHA-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Panicum hallii ("FIL2") [Reaction:R-PVE-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Pistacia vera [Reaction:R-CSA-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Cucumis sativus [Reaction:R-BNA-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Brassica napus [Reaction:R-FEX-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Fraxinus excelsior (European ash) [Reaction:R-AUM-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Aegilops umbellulata [Reaction:R-QSU-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Quercus suber [Reaction:R-CCA-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Cajanus cajan [Reaction:R-OGU-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Oryza glumaepatula [Reaction:R-MDO-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Malus domestica [Reaction:R-PSA-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Pisum sativum [Reaction:R-ITR-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Ipomoea triloba [Reaction:R-ACO-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Ananas comosus [Reaction:R-VVN-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Vitis vinifera [Reaction:R-CCR-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Chondrus crispus [Reaction:R-PVU-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Phaseolus vulgaris [Reaction:R-OBA-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Oryza barthii [Reaction:R-LPR-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Lolium perenne [Reaction:R-TTI-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Triticum timopheevii subsp. timopheevii [Reaction:R-DEX-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Digitaria exilis [Reaction:R-CCN-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Coffea canephora [Reaction:R-CST-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Camelina sativa [Reaction:R-CML-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Cucumis melo [Reaction:R-CAR-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Cicer arietinum [Reaction:R-COL-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Corchorus olitorius [Reaction:R-LAN-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Lupinus angustifolius [Reaction:R-ATA-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Aegilops tauschii [Reaction:R-CME-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Cyanidioschyzon merolae [Reaction:R-SIN-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Sesamum indicum [Reaction:R-JRE-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Juglans regia [Reaction:R-PDA-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Phoenix dactylifera [Reaction:R-PPE-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Prunus persica [Reaction:R-TAE-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Triticum aestivum [Reaction:R-TPR-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Trifolium pratense [Reaction:R-TDI-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Triticum dicoccoides [Reaction:R-CCP-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Corchorus capsularis [Reaction:R-CRU-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Capsella rubella [Reaction:R-GSO-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Glycine soja [Reaction:R-OSI-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Oryza sativa Indica Group [Reaction:R-MPO-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Marchantia polymorpha [Reaction:R-PAB-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Picea abies [Reaction:R-HLH-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Humulus lupulus [Reaction:R-ORU-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Oryza rufipogon [Reaction:R-CRE-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Chlamydomonas reinhardtii [Reaction:R-NAT-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Nicotiana attenuata [Reaction:R-LST-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Lathyrus sativus [Reaction:R-OGL-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Oryza glaberrima [Reaction:R-CSK-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Cannabis sativa subsp. indica [Reaction:R-ECG-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Echinochloa crus-galli [Reaction:R-BDI-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Brachypodium distachyon [Reaction:R-MES-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Manihot esculenta [Reaction:R-PSO-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Papaver somniferum [Reaction:R-ASA-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Avena sativa [Reaction:R-PED-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Phyllostachys edulis [Reaction:R-SHI-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Salvia hispanica [Reaction:R-AHY-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Arachis hypogaea [Reaction:R-SLY-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Solanum lycopersicum [Reaction:R-FCR-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Ficus carica [Reaction:R-FVE-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Fragaria vesca [Reaction:R-BRA-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Brassica rapa [Reaction:R-GRA-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Gossypium raimondii [Reaction:R-CAN-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Capsicum annuum [Reaction:R-OOF-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Oryza officinalis [Reaction:R-SIT-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Setaria italica [Reaction:R-TTU-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Triticum turgidum [Reaction:R-OME-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Oryza meridionalis [Reaction:R-OGR-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Oryza meyeriana var. granulata [Reaction:R-AOF-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Asparagus officinalis [Reaction:R-TUR-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Triticum urartu [Reaction:R-SVI-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Setaria viridis [Reaction:R-NCO-8986551] 2-ketoadipate + lipoamide ---> S-glutaryldihydroliopamide + CO2 - Nymphaea colorata
output	[SimpleEntity:R-ALL-29376] CO2 [mitochondrial matrix] [SimpleEntity:R-ALL-70006] S-glutaryldihydrolipoamide [mitochondrial matrix]
precedingEvent	[Reaction:R-OSA-1121512] alpha-aminoadipate + alpha-ketoglutarate ---> alpha-ketoadipate + L-Glu - Oryza sativa
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-8986551

Referrals

(hasEvent)	[Pathway:R-OSA-1119365] Lysine degradation II - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-8986553] S-glutaryldihydrolipoamide + succinyl-CoA ----> Glutaryl-CoA + S-succinyldihydrolipoamide - Oryza sativa