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1-deoxy-D-xylulose-5-phosphate synthase

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catalystActivity	[CatalystActivity:1119011] 1-deoxy-D-xylulose-5-phosphate synthase activity of 1-deoxy-D-xylulose-5-phosphate synthase [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:1154434] EC-NUMBER:2.2.1.7 [DatabaseIdentifier:1152113] RiceCyc:DXS-RXN
dbId	1121157
displayName	1-deoxy-D-xylulose-5-phosphate synthase
eventOf	[Pathway:R-OSA-1119594] Pyridoxal 5'-phosphate biosynthesis - Oryza sativa [Pathway:R-OSA-1119629] Thiamine biosynthesis - Oryza sativa
followingEvent	[Reaction:R-OSA-1120111] 2-C-methyl-D-erythritol-4-phosphate+NADP+->1-deoxy-D-xylulose 5-phosphate+NADPH - Oryza sativa [Reaction:R-OSA-1120781] L-tyrosine+1-deoxy-D-xylulose 5-phosphate+a ThiS persulfide->a ThiF protein+4-methyl-5-(beta-hydroxyethyl)thiazole phosphate+4-hydroxybenzyl alcohol+C1 of tyrosine+a ThiS sulfur-carrier protein - Oryza sativa [Reaction:R-OSA-1119778] 1-deoxy-D-xylulose 5-phosphate+1-amino-propan-2-one-3-phosphate->pyridoxine-5'-phosphate+phosphate+H2O - Oryza sativa
input	[SimpleEntity:R-ALL-1131772] D-glyceraldehyde-3-phosphate [cytosol] [SimpleEntity:R-ALL-29398] PYR [cytosol]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	1-deoxy-D-xylulose-5-phosphate synthase pyruvate+D-glyceraldehyde-3-phosphate->1-deoxy-D-xylulose 5-phosphate+CO2 DXS-RXN biochemicalReaction76082
orthologousEvent	[Reaction:R-SLY-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Solanum lycopersicum [Reaction:R-ACH-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Actinidia chinensis [Reaction:R-LPR-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Lolium perenne [Reaction:R-CCI-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Corymbia citriodora [Reaction:R-PTI-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Populus trichocarpa [Reaction:R-MGU-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Erythranthe guttata [Reaction:R-NNU-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Nelumbo nucifera [Reaction:R-DRO-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Dioscorea rotundata [Reaction:R-CRE-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Chlamydomonas reinhardtii [Reaction:R-PAB-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Picea abies [Reaction:R-SIN-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Sesamum indicum [Reaction:R-QSU-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Quercus suber [Reaction:R-AOF-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Asparagus officinalis [Reaction:R-DEX-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Digitaria exilis [Reaction:R-ACO-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Ananas comosus [Reaction:R-TTU-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Triticum turgidum [Reaction:R-SHI-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Salvia hispanica [Reaction:R-NCO-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Nymphaea colorata [Reaction:R-MES-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Manihot esculenta [Reaction:R-TCA-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Theobroma cacao [Reaction:R-SPC-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Synechocystis sp. PCC 6803 [Reaction:R-GSU-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Galdieria sulphuraria [Reaction:R-CSC-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Cannabis sativa [Reaction:R-CCD-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Cynara cardunculus var. scolymus [Reaction:R-FVE-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Fragaria vesca [Reaction:R-SIT-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Setaria italica [Reaction:R-CAR-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Cicer arietinum [Reaction:R-CRU-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Capsella rubella [Reaction:R-HLP-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Humulus lupulus var. lupulus [Reaction:R-BJU-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Brassica juncea [Reaction:R-TAE-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Triticum aestivum [Reaction:R-CCR-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Chondrus crispus [Reaction:R-CBA-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Chara braunii [Reaction:R-PPA-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Physcomitrella patens [Reaction:R-CCA-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Cajanus cajan [Reaction:R-PHH-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Panicum hallii var. hallii ("HAL2") [Reaction:R-OOF-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Oryza officinalis [Reaction:R-VVN-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Vitis vinifera [Reaction:R-OSI-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Oryza sativa Indica Group [Reaction:R-OGR-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Oryza meyeriana var. granulata [Reaction:R-SVI-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Setaria viridis [Reaction:R-GSO-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Glycine soja [Reaction:R-ATH-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Arabidopsis thaliana [Reaction:R-CML-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Cucumis melo [Reaction:R-TTI-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Triticum timopheevii subsp. timopheevii [Reaction:R-ECG-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Echinochloa crus-galli [Reaction:R-BNA-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Brassica napus [Reaction:R-LSA-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Lactuca sativa [Reaction:R-TUR-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Triticum urartu [Reaction:R-NAT-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Nicotiana attenuata [Reaction:R-PAV-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Prunus avium [Reaction:R-AHY-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Arachis hypogaea [Reaction:R-JRE-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Juglans regia [Reaction:R-BVU-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Beta vulgaris [Reaction:R-FEX-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Fraxinus excelsior (European ash) [Reaction:R-OLU-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Ostreococcus lucimarinus [Reaction:R-BRA-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Brassica rapa [Reaction:R-MAC-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Musa acuminata [Reaction:R-OBA-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Oryza barthii [Reaction:R-DCA-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Daucus carota [Reaction:R-ZJA-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Zoysia japonica [Reaction:R-OES-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Olea europaea var. sylvestris [Reaction:R-OEU-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Olea europaea [Reaction:R-ALY-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Arabidopsis lyrata [Reaction:R-OGL-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Oryza glaberrima [Reaction:R-FCR-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Ficus carica [Reaction:R-AHA-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Arabidopsis halleri [Reaction:R-TSP-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Triticum spelta subsp. spelta [Reaction:R-CCP-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Corchorus capsularis [Reaction:R-ETE-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Eragrostis tef [Reaction:R-CSA-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Cucumis sativus [Reaction:R-CCL-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Citrus clementina [Reaction:R-CCN-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Coffea canephora [Reaction:R-VFA-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Vicia faba var. faba [Reaction:R-SSP-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Saccharum spontaneum [Reaction:R-MDO-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Malus domestica [Reaction:R-PSO-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Papaver somniferum [Reaction:R-OPU-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Oryza punctata [Reaction:R-HAN-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Helianthus annuus [Reaction:R-CAN-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Capsicum annuum [Reaction:R-MTR-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Medicago truncatula [Reaction:R-RCH-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Rosa chinensis [Reaction:R-CLA-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Citrullus lanatus [Reaction:R-CSK-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Cannabis sativa subsp. indica [Reaction:R-OLO-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Oryza longistaminata [Reaction:R-PDA-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Phoenix dactylifera [Reaction:R-OMI-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Oryza minuta [Reaction:R-QLO-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Quercus lobata [Reaction:R-VRA-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Vigna radiata [Reaction:R-ATR-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Amborella trichopoda [Reaction:R-PSA-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Pisum sativum [Reaction:R-ONI-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Oryza nivara [Reaction:R-VUN-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Vigna unguiculata [Reaction:R-GMA-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Glycine max [Reaction:R-SCR-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Secale cereale [Reaction:R-PVU-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Phaseolus vulgaris [Reaction:R-BDI-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Brachypodium distachyon [Reaction:R-LST-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Lathyrus sativus [Reaction:R-OAU-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Oryza australiensis [Reaction:R-VAN-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Vigna angularis [Reaction:R-STU-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Solanum tuberosum [Reaction:R-SBI-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Sorghum bicolor [Reaction:R-EGR-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Eucalyptus grandis [Reaction:R-LAN-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Lupinus angustifolius [Reaction:R-TPR-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Trifolium pratense [Reaction:R-AIP-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Arachis ipaensis [Reaction:R-PVE-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Pistacia vera [Reaction:R-HVU-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Hordeum vulgare [Reaction:R-GRA-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Gossypium raimondii [Reaction:R-PPE-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Prunus persica [Reaction:R-ASA-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Avena sativa [Reaction:R-ZMA-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Zea mays [Reaction:R-CST-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Camelina sativa [Reaction:R-HLH-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Humulus lupulus [Reaction:R-PED-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Phyllostachys edulis [Reaction:R-OGU-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Oryza glumaepatula [Reaction:R-ITR-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Ipomoea triloba [Reaction:R-LPE-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Leersia perrieri [Reaction:R-JCU-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Jatropha curcas [Reaction:R-BOL-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Brassica oleracea [Reaction:R-ZMY-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Zea mays ver5 [Reaction:R-OBR-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Oryza brachyantha [Reaction:R-CQI-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Chenopodium quinoa [Reaction:R-PHA-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Panicum hallii ("FIL2") [Reaction:R-ORU-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Oryza rufipogon [Reaction:R-TDI-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Triticum dicoccoides [Reaction:R-ATA-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Aegilops tauschii [Reaction:R-OME-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Oryza meridionalis [Reaction:R-PTA-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Pinus taeda [Reaction:R-CME-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Cyanidioschyzon merolae [Reaction:R-COL-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Corchorus olitorius [Reaction:R-CSI-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Citrus sinensis [Reaction:R-ECU-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Eragrostis curvula [Reaction:R-AUM-1121157] 1-deoxy-D-xylulose-5-phosphate synthase - Aegilops umbellulata
output	[SimpleEntity:R-ALL-1130695] 1-deoxy-D-xylulose 5-phosphate [cytosol] [SimpleEntity:R-ALL-113528] CO2 [cytosol]
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1121157
summation	[Summation:2872513] D-glyceraldehyde-3-phosphate is converted to 1-deoxy-D-xylul...

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