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hydroxymethylbilane synthase

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catalystActivity	[CatalystActivity:10996677] hydroxymethylbilane synthase activity of hydroxymethylbilane synthase (LOC_OS02G07230.1) [plastid stroma]
compartment	[Compartment:1141] plastid stroma
created	[InstanceEdit:10992009] Elser, Justin, 2025-03-25
dbId	10996679
displayName	hydroxymethylbilane synthase
eventOf	[Pathway:R-TPR-4827054] Tetrapyrrole biosynthesis I - Trifolium pratense
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Reaction:R-TPR-4827058] uroporphyrinogen-III synthase - Trifolium pratense
inferredFrom	[Reaction:R-OSA-4827045] hydroxymethylbilane synthase - Oryza sativa
input	[SimpleEntity:R-ALL-1168755] H2O [plastid stroma] 4 × [SimpleEntity:R-ALL-4827082] PBG [plastid stroma]
isInDisease	false
isInferred	true
name	hydroxymethylbilane synthase
output	[SimpleEntity:R-ALL-4827048] HMBL [plastid stroma] 4 × [SimpleEntity:R-ALL-4789078] NH3 [plastid stroma]
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9030292] Trifolium pratense
stId	R-TPR-4827045
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

Referrals

(hasEvent)	[Pathway:R-TPR-4827054] Tetrapyrrole biosynthesis I - Trifolium pratense
(precedingEvent)	[Reaction:R-TPR-4827058] uroporphyrinogen-III synthase - Trifolium pratense
(inferredTo)	[Reaction:R-OSA-4827045] hydroxymethylbilane synthase - Oryza sativa

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