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UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase

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catalystActivity	[CatalystActivity:10049146] UDP-N-acetylmuramoylalanine-D-glutamate ligase activity of Mur ligase family protein (LOC_OS10G40130.1) [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10044388] Elser, Justin, 2025-03-24
dbId	10049150
displayName	UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase
eventOf	[Pathway:R-SSP-1119436] Peptidoglycan biosynthesis I - Saccharum spontaneum
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Reaction:R-SSP-1120868] UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl- D-alanine ligase - Saccharum spontaneum
inferredFrom	[Reaction:R-OSA-1120870] UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase - Oryza sativa
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-1131733] meso-diaminopimelate [cytosol] [SimpleEntity:R-ALL-1131663] UDP-N-acetylmuramoyl-L-alanyl-D-glutamate [cytosol]
isInDisease	false
isInferred	true
name	UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase UDP-N-acetylmuramyl-tripeptide synthetase synthetase UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate biochemicalReaction6550
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol] [SimpleEntity:R-ALL-1131879] UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate [cytosol]
precedingEvent	[Reaction:R-SSP-1120897] UDP-N-acetylmuramoylalanine--D-glutamate ligase - Saccharum spontaneum
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9689251] Saccharum spontaneum
stId	R-SSP-1120870
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

Referrals

(hasEvent)	[Pathway:R-SSP-1119436] Peptidoglycan biosynthesis I - Saccharum spontaneum
(precedingEvent)	[Reaction:R-SSP-1120868] UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl- D-alanine ligase - Saccharum spontaneum
(inferredTo)	[Reaction:R-OSA-1120870] UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase - Oryza sativa