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GTP cyclohydrolase II

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catalystActivity	[CatalystActivity:11227431] GTP cyclohydrolase II activity of GTP cyclohydrolase II [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:11225385] Elser, Justin, 2025-03-26
dbId	11227433
displayName	GTP cyclohydrolase II
eventOf	[Pathway:R-RCH-1119379] Flavin biosynthesis - Rosa chinensis
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Reaction:R-RCH-1120864] diaminohydroxyphosphoribosylaminopyrimidine deaminase - Rosa chinensis
inferredFrom	[Reaction:R-OSA-1120402] GTP cyclohydrolase II - Oryza sativa
input	[SimpleEntity:R-ALL-29438] GTP [cytosol] 3 × [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
name	GTP cyclohydrolase II biochemicalReaction32654
output	[SimpleEntity:R-ALL-1131435] 2,5-diamino-6-(ribosylamino)-4-(3H)-pyrimidinone 5'-phosphate [cytosol] [SimpleEntity:R-ALL-29460] HCOOH [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol]
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9764215] Rosa chinensis
stId	R-RCH-1120402
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

Referrals

(hasEvent)	[Pathway:R-RCH-1119379] Flavin biosynthesis - Rosa chinensis
(precedingEvent)	[Reaction:R-RCH-1120864] diaminohydroxyphosphoribosylaminopyrimidine deaminase - Rosa chinensis
(inferredTo)	[Reaction:R-OSA-1120402] GTP cyclohydrolase II - Oryza sativa

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