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2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

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catalystActivity	[CatalystActivity:11227280] 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. [plastid stroma]
compartment	[Compartment:1141] plastid stroma
created	[InstanceEdit:11225385] Elser, Justin, 2025-03-26
dbId	11227282
displayName	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
eventOf	[Pathway:R-RCH-1119464] Methylerythritol phosphate pathway - Rosa chinensis
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Reaction:R-RCH-4723700] 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate+H2O+a protein disulfide->2-C-methyl-D-erythritol-2,4-cyclodiphosphate+a protein dithiol - Rosa chinensis
inferredFrom	[Reaction:R-OSA-1120374] 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase - Oryza sativa
input	[SimpleEntity:R-ALL-1131978] 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol [plastid stroma]
isInDisease	false
isInferred	true
name	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase MECDP-synthase biochemicalReaction9758
output	[SimpleEntity:R-ALL-4723650] 2-C-methyl-D-erythritol-2,4-cyclodiphosphate [plastid stroma] [SimpleEntity:R-ALL-4723662] cytidine 5'-monophosphate [plastid stroma]
precedingEvent	[Reaction:R-RCH-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Rosa chinensis
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9764215] Rosa chinensis
stId	R-RCH-1120374
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

Referrals

(hasEvent)	[Pathway:R-RCH-1119464] Methylerythritol phosphate pathway - Rosa chinensis
(precedingEvent)	[Reaction:R-RCH-4723700] 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate+H2O+a protein disulfide->2-C-methyl-D-erythritol-2,4-cyclodiphosphate+a protein dithiol - Rosa chinensis
(inferredTo)	[Reaction:R-OSA-1120374] 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase - Oryza sativa