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porphobilinogen synthase

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catalystActivity	[CatalystActivity:4827053] porphobilinogen synthase activity of porphobilinogen synthase (LOC_OS06G49110.1) [plastid stroma]
compartment	[Compartment:1141] plastid stroma
created	[InstanceEdit:4827073] D'Eustachio, P, 2013-10-29
crossReference	[DatabaseIdentifier:27942] EC:4.2.1.24
dbId	4827076
displayName	porphobilinogen synthase
eventOf	[Pathway:R-OSA-4827054] Tetrapyrrole biosynthesis I - Oryza sativa
followingEvent	[Reaction:R-OSA-4827045] hydroxymethylbilane synthase - Oryza sativa
input	2 × [SimpleEntity:R-ALL-4827083] 5-amino-levulinate [plastid stroma]
isChimeric	false
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	porphobilinogen synthase
orthologousEvent	[Reaction:R-GSU-4827076] porphobilinogen synthase - Galdieria sulphuraria [Reaction:R-CLA-4827076] porphobilinogen synthase - Citrullus lanatus [Reaction:R-ONI-4827076] porphobilinogen synthase - Oryza nivara [Reaction:R-TTU-4827076] porphobilinogen synthase - Triticum turgidum [Reaction:R-PTI-4827076] porphobilinogen synthase - Populus trichocarpa [Reaction:R-HVU-4827076] porphobilinogen synthase - Hordeum vulgare [Reaction:R-NCO-4827076] porphobilinogen synthase - Nymphaea colorata [Reaction:R-VVN-4827076] porphobilinogen synthase - Vitis vinifera [Reaction:R-SSP-4827076] porphobilinogen synthase - Saccharum spontaneum [Reaction:R-OES-4827076] porphobilinogen synthase - Olea europaea var. sylvestris [Reaction:R-SIN-4827076] porphobilinogen synthase - Sesamum indicum [Reaction:R-OBR-4827076] porphobilinogen synthase - Oryza brachyantha [Reaction:R-DRO-4827076] porphobilinogen synthase - Dioscorea rotundata [Reaction:R-EGR-4827076] porphobilinogen synthase - Eucalyptus grandis [Reaction:R-ATA-4827076] porphobilinogen synthase - Aegilops tauschii [Reaction:R-SCR-4827076] porphobilinogen synthase - Secale cereale [Reaction:R-PAB-4827076] porphobilinogen synthase - Picea abies [Reaction:R-BJU-4827076] porphobilinogen synthase - Brassica juncea [Reaction:R-TAE-4827076] porphobilinogen synthase - Triticum aestivum [Reaction:R-MDO-4827076] porphobilinogen synthase - Malus domestica [Reaction:R-PPE-4827076] porphobilinogen synthase - Prunus persica [Reaction:R-OEU-4827076] porphobilinogen synthase - Olea europaea [Reaction:R-CAN-4827076] porphobilinogen synthase - Capsicum annuum [Reaction:R-DEX-4827076] porphobilinogen synthase - Digitaria exilis [Reaction:R-STU-4827076] porphobilinogen synthase - Solanum tuberosum [Reaction:R-PAV-4827076] porphobilinogen synthase - Prunus avium [Reaction:R-ITR-4827076] porphobilinogen synthase - Ipomoea triloba [Reaction:R-CCL-4827076] porphobilinogen synthase - Citrus clementina [Reaction:R-MTR-4827076] porphobilinogen synthase - Medicago truncatula [Reaction:R-NNU-4827076] porphobilinogen synthase - Nelumbo nucifera [Reaction:R-TUR-4827076] porphobilinogen synthase - Triticum urartu [Reaction:R-COL-4827076] porphobilinogen synthase - Corchorus olitorius [Reaction:R-ORU-4827076] porphobilinogen synthase - Oryza rufipogon [Reaction:R-VFA-4827076] porphobilinogen synthase - Vicia faba var. faba [Reaction:R-ZMA-4827076] porphobilinogen synthase - Zea mays [Reaction:R-LPR-4827076] porphobilinogen synthase - Lolium perenne [Reaction:R-CRU-4827076] porphobilinogen synthase - Capsella rubella [Reaction:R-PVE-4827076] porphobilinogen synthase - Pistacia vera [Reaction:R-DCA-4827076] porphobilinogen synthase - Daucus carota [Reaction:R-LST-4827076] porphobilinogen synthase - Lathyrus sativus [Reaction:R-VAN-4827076] porphobilinogen synthase - Vigna angularis [Reaction:R-OLO-4827076] porphobilinogen synthase - Oryza longistaminata [Reaction:R-PHA-4827076] porphobilinogen synthase - Panicum hallii ("FIL2") [Reaction:R-GMA-4827076] porphobilinogen synthase - Glycine max [Reaction:R-SMO-4827076] porphobilinogen synthase - Selaginella moellendorffii [Reaction:R-ECG-4827076] porphobilinogen synthase - Echinochloa crus-galli [Reaction:R-HLP-4827076] porphobilinogen synthase - Humulus lupulus var. lupulus [Reaction:R-MAC-4827076] porphobilinogen synthase - Musa acuminata [Reaction:R-ASA-4827076] porphobilinogen synthase - Avena sativa [Reaction:R-VUN-4827076] porphobilinogen synthase - Vigna unguiculata [Reaction:R-HAN-4827076] porphobilinogen synthase - Helianthus annuus [Reaction:R-RCH-4827076] porphobilinogen synthase - Rosa chinensis [Reaction:R-PPA-4827076] porphobilinogen synthase - Physcomitrella patens [Reaction:R-AOF-4827076] porphobilinogen synthase - Asparagus officinalis [Reaction:R-CST-4827076] porphobilinogen synthase - Camelina sativa [Reaction:R-CSC-4827076] porphobilinogen synthase - Cannabis sativa [Reaction:R-ADU-4827076] porphobilinogen synthase - Arachis duranensis [Reaction:R-CSK-4827076] porphobilinogen synthase - Cannabis sativa subsp. indica [Reaction:R-GSO-4827076] porphobilinogen synthase - Glycine soja [Reaction:R-CQI-4827076] porphobilinogen synthase - Chenopodium quinoa [Reaction:R-CSA-4827076] porphobilinogen synthase - Cucumis sativus [Reaction:R-PHH-4827076] porphobilinogen synthase - Panicum hallii var. hallii ("HAL2") [Reaction:R-SBI-4827076] porphobilinogen synthase - Sorghum bicolor [Reaction:R-AHA-4827076] porphobilinogen synthase - Arabidopsis halleri [Reaction:R-FVE-4827076] porphobilinogen synthase - Fragaria vesca [Reaction:R-JRE-4827076] porphobilinogen synthase - Juglans regia [Reaction:R-ACO-4827076] porphobilinogen synthase - Ananas comosus [Reaction:R-CAR-4827076] porphobilinogen synthase - Cicer arietinum [Reaction:R-OGL-4827076] porphobilinogen synthase - Oryza glaberrima [Reaction:R-CSI-4827076] porphobilinogen synthase - Citrus sinensis [Reaction:R-AHY-4827076] porphobilinogen synthase - Arachis hypogaea [Reaction:R-SHI-4827076] porphobilinogen synthase - Salvia hispanica [Reaction:R-ETE-4827076] porphobilinogen synthase - Eragrostis tef [Reaction:R-MGU-4827076] porphobilinogen synthase - Erythranthe guttata [Reaction:R-CCI-4827076] porphobilinogen synthase - Corymbia citriodora [Reaction:R-HLH-4827076] porphobilinogen synthase - Humulus lupulus [Reaction:R-AUM-4827076] porphobilinogen synthase - Aegilops umbellulata [Reaction:R-MPO-4827076] porphobilinogen synthase - Marchantia polymorpha [Reaction:R-ZJA-4827076] porphobilinogen synthase - Zoysia japonica [Reaction:R-OSI-4827076] porphobilinogen synthase - Oryza sativa Indica Group [Reaction:R-SIT-4827076] porphobilinogen synthase - Setaria italica [Reaction:R-PTA-4827076] porphobilinogen synthase - Pinus taeda [Reaction:R-CCD-4827076] porphobilinogen synthase - Cynara cardunculus var. scolymus [Reaction:R-PED-4827076] porphobilinogen synthase - Phyllostachys edulis [Reaction:R-CCN-4827076] porphobilinogen synthase - Coffea canephora [Reaction:R-GRA-4827076] porphobilinogen synthase - Gossypium raimondii [Reaction:R-CCR-4827076] porphobilinogen synthase - Chondrus crispus [Reaction:R-ZMY-4827076] porphobilinogen synthase - Zea mays ver5 [Reaction:R-TDI-4827076] porphobilinogen synthase - Triticum dicoccoides [Reaction:R-QLO-4827076] porphobilinogen synthase - Quercus lobata [Reaction:R-CCP-4827076] porphobilinogen synthase - Corchorus capsularis [Reaction:R-SVI-4827076] porphobilinogen synthase - Setaria viridis [Reaction:R-PVU-4827076] porphobilinogen synthase - Phaseolus vulgaris [Reaction:R-CME-4827076] porphobilinogen synthase - Cyanidioschyzon merolae [Reaction:R-ALY-4827076] porphobilinogen synthase - Arabidopsis lyrata [Reaction:R-PSO-4827076] porphobilinogen synthase - Papaver somniferum [Reaction:R-TCA-4827076] porphobilinogen synthase - Theobroma cacao [Reaction:R-OMI-4827076] porphobilinogen synthase - Oryza minuta [Reaction:R-ACH-4827076] porphobilinogen synthase - Actinidia chinensis [Reaction:R-BDI-4827076] porphobilinogen synthase - Brachypodium distachyon [Reaction:R-CRE-4827076] porphobilinogen synthase - Chlamydomonas reinhardtii [Reaction:R-VRA-4827076] porphobilinogen synthase - Vigna radiata [Reaction:R-TSP-4827076] porphobilinogen synthase - Triticum spelta subsp. spelta [Reaction:R-LSA-4827076] porphobilinogen synthase - Lactuca sativa [Reaction:R-OPU-4827076] porphobilinogen synthase - Oryza punctata [Reaction:R-LAN-4827076] porphobilinogen synthase - Lupinus angustifolius [Reaction:R-OLU-4827076] porphobilinogen synthase - Ostreococcus lucimarinus [Reaction:R-BVU-4827076] porphobilinogen synthase - Beta vulgaris [Reaction:R-MES-4827076] porphobilinogen synthase - Manihot esculenta [Reaction:R-PDA-4827076] porphobilinogen synthase - Phoenix dactylifera [Reaction:R-BNA-4827076] porphobilinogen synthase - Brassica napus [Reaction:R-ATR-4827076] porphobilinogen synthase - Amborella trichopoda [Reaction:R-CML-4827076] porphobilinogen synthase - Cucumis melo [Reaction:R-BRA-4827076] porphobilinogen synthase - Brassica rapa [Reaction:R-QSU-4827076] porphobilinogen synthase - Quercus suber [Reaction:R-AIP-4827076] porphobilinogen synthase - Arachis ipaensis [Reaction:R-TTI-4827076] porphobilinogen synthase - Triticum timopheevii subsp. timopheevii [Reaction:R-BOL-4827076] porphobilinogen synthase - Brassica oleracea [Reaction:R-FEX-4827076] porphobilinogen synthase - Fraxinus excelsior (European ash) [Reaction:R-NAT-4827076] porphobilinogen synthase - Nicotiana attenuata [Reaction:R-ATH-4827076] porphobilinogen synthase - Arabidopsis thaliana [Reaction:R-OGR-4827076] porphobilinogen synthase - Oryza meyeriana var. granulata [Reaction:R-LPE-4827076] porphobilinogen synthase - Leersia perrieri [Reaction:R-OAU-4827076] porphobilinogen synthase - Oryza australiensis [Reaction:R-SPC-4827076] porphobilinogen synthase - Synechocystis sp. PCC 6803 [Reaction:R-PSA-4827076] porphobilinogen synthase - Pisum sativum [Reaction:R-ECU-4827076] porphobilinogen synthase - Eragrostis curvula [Reaction:R-SLY-4827076] porphobilinogen synthase - Solanum lycopersicum [Reaction:R-OOF-4827076] porphobilinogen synthase - Oryza officinalis [Reaction:R-FCR-4827076] porphobilinogen synthase - Ficus carica [Reaction:R-CCA-4827076] porphobilinogen synthase - Cajanus cajan [Reaction:R-OBA-4827076] porphobilinogen synthase - Oryza barthii
output	2 × [SimpleEntity:R-ALL-1168755] H2O [plastid stroma] [SimpleEntity:R-ALL-4827082] PBG [plastid stroma]
precedingEvent	[Reaction:R-OSA-4827063] glutamate-1-semialdehyde 2,1-aminomutase - Oryza sativa
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-4827076
summation	[Summation:4827055] 5-amino-levulinate is converted to porphobilinogen by enzyma...

Referrals

(hasEvent)	[Pathway:R-OSA-4827054] Tetrapyrrole biosynthesis I - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-4827045] hydroxymethylbilane synthase - Oryza sativa