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a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP

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catalystActivity	[CatalystActivity:1119028] tetrahydrofolylpolyglutamate synthase activity of tetrahydrofolate synthase [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:28138] EC:6.3.2.17 [DatabaseIdentifier:1146298] RiceCyc:RXN0-2921
dbId	1121539
displayName	a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP
eventOf	[Pathway:R-OSA-1119617] Folate polyglutamylation I - Oryza sativa
input	[SimpleEntity:R-ALL-1132205] 5,10-methylenetetrahydrofolate(2-) [cytosol] [SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-29404] L-Glu [cytosol]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP RXN0-2921 biochemicalReaction6666
orthologousEvent	[Reaction:R-CCI-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Corymbia citriodora [Reaction:R-LPR-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Lolium perenne [Reaction:R-ACO-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Ananas comosus [Reaction:R-LPE-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Leersia perrieri [Reaction:R-CCL-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Citrus clementina [Reaction:R-ECG-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Echinochloa crus-galli [Reaction:R-CML-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Cucumis melo [Reaction:R-AOF-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Asparagus officinalis [Reaction:R-JRE-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Juglans regia [Reaction:R-BNA-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Brassica napus [Reaction:R-ASA-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Avena sativa [Reaction:R-EGR-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Eucalyptus grandis [Reaction:R-ACH-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Actinidia chinensis [Reaction:R-DCA-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Daucus carota [Reaction:R-CQI-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Chenopodium quinoa [Reaction:R-BRA-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Brassica rapa [Reaction:R-VVN-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Vitis vinifera [Reaction:R-BJU-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Brassica juncea [Reaction:R-ECU-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Eragrostis curvula [Reaction:R-PTA-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Pinus taeda [Reaction:R-ADU-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Arachis duranensis [Reaction:R-PTI-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Populus trichocarpa [Reaction:R-OGU-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Oryza glumaepatula [Reaction:R-AHY-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Arachis hypogaea [Reaction:R-LAN-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Lupinus angustifolius [Reaction:R-AHA-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Arabidopsis halleri [Reaction:R-PED-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Phyllostachys edulis [Reaction:R-NCO-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Nymphaea colorata [Reaction:R-CCN-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Coffea canephora [Reaction:R-BDI-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Brachypodium distachyon [Reaction:R-CCD-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Cynara cardunculus var. scolymus [Reaction:R-BVU-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Beta vulgaris [Reaction:R-OBR-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Oryza brachyantha [Reaction:R-TDI-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Triticum dicoccoides [Reaction:R-PSA-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Pisum sativum [Reaction:R-ORU-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Oryza rufipogon [Reaction:R-AUM-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Aegilops umbellulata [Reaction:R-SLY-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Solanum lycopersicum [Reaction:R-NAT-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Nicotiana attenuata [Reaction:R-OME-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Oryza meridionalis [Reaction:R-CCA-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Cajanus cajan [Reaction:R-SIT-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Setaria italica [Reaction:R-TTU-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Triticum turgidum [Reaction:R-SHI-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Salvia hispanica [Reaction:R-OOF-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Oryza officinalis [Reaction:R-CST-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Camelina sativa [Reaction:R-ZMA-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Zea mays [Reaction:R-QLO-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Quercus lobata [Reaction:R-CAN-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Capsicum annuum [Reaction:R-OLU-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Ostreococcus lucimarinus [Reaction:R-CRU-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Capsella rubella [Reaction:R-SIN-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Sesamum indicum [Reaction:R-PPE-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Prunus persica [Reaction:R-OLO-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Oryza longistaminata [Reaction:R-OGL-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Oryza glaberrima [Reaction:R-PAB-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Picea abies [Reaction:R-FCR-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Ficus carica [Reaction:R-OBA-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Oryza barthii [Reaction:R-CSC-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Cannabis sativa [Reaction:R-CAR-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Cicer arietinum [Reaction:R-OMI-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Oryza minuta [Reaction:R-OEU-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Olea europaea [Reaction:R-STU-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Solanum tuberosum [Reaction:R-LSA-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Lactuca sativa [Reaction:R-TUR-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Triticum urartu [Reaction:R-MPO-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Marchantia polymorpha [Reaction:R-VRA-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Vigna radiata [Reaction:R-ZJA-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Zoysia japonica [Reaction:R-JCU-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Jatropha curcas [Reaction:R-HLH-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Humulus lupulus [Reaction:R-ATH-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Arabidopsis thaliana [Reaction:R-GRA-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Gossypium raimondii [Reaction:R-ONI-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Oryza nivara [Reaction:R-CLA-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Citrullus lanatus [Reaction:R-PHH-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Panicum hallii var. hallii ("HAL2") [Reaction:R-SVI-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Setaria viridis [Reaction:R-OES-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Olea europaea var. sylvestris [Reaction:R-SSP-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Saccharum spontaneum [Reaction:R-VAN-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Vigna angularis [Reaction:R-GSO-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Glycine soja [Reaction:R-CBA-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Chara braunii [Reaction:R-SBI-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Sorghum bicolor [Reaction:R-AIP-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Arachis ipaensis [Reaction:R-COL-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Corchorus olitorius [Reaction:R-ETE-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Eragrostis tef [Reaction:R-PVE-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Pistacia vera [Reaction:R-SPC-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Synechocystis sp. PCC 6803 [Reaction:R-MAC-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Musa acuminata [Reaction:R-SMO-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Selaginella moellendorffii [Reaction:R-ZMY-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Zea mays ver5 [Reaction:R-CCP-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Corchorus capsularis [Reaction:R-HAN-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Helianthus annuus [Reaction:R-DRO-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Dioscorea rotundata [Reaction:R-CSA-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Cucumis sativus [Reaction:R-ALY-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Arabidopsis lyrata [Reaction:R-MTR-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Medicago truncatula [Reaction:R-VFA-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Vicia faba var. faba [Reaction:R-VUN-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Vigna unguiculata [Reaction:R-HVU-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Hordeum vulgare [Reaction:R-RCH-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Rosa chinensis [Reaction:R-OAU-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Oryza australiensis [Reaction:R-PAV-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Prunus avium [Reaction:R-MGU-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Erythranthe guttata [Reaction:R-MDO-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Malus domestica [Reaction:R-ATR-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Amborella trichopoda [Reaction:R-PDA-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Phoenix dactylifera [Reaction:R-CSI-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Citrus sinensis [Reaction:R-PSO-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Papaver somniferum [Reaction:R-PPA-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Physcomitrella patens [Reaction:R-FVE-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Fragaria vesca [Reaction:R-CRE-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Chlamydomonas reinhardtii [Reaction:R-FEX-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Fraxinus excelsior (European ash) [Reaction:R-TCA-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Theobroma cacao [Reaction:R-PVU-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Phaseolus vulgaris [Reaction:R-TTI-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Triticum timopheevii subsp. timopheevii [Reaction:R-CSK-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Cannabis sativa subsp. indica [Reaction:R-GMA-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Glycine max [Reaction:R-OSI-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Oryza sativa Indica Group [Reaction:R-TAE-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Triticum aestivum [Reaction:R-LST-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Lathyrus sativus [Reaction:R-TPR-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Trifolium pratense [Reaction:R-ATA-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Aegilops tauschii [Reaction:R-OPU-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Oryza punctata [Reaction:R-SCR-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Secale cereale [Reaction:R-OGR-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Oryza meyeriana var. granulata [Reaction:R-PHA-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Panicum hallii ("FIL2") [Reaction:R-QSU-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Quercus suber [Reaction:R-MES-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Manihot esculenta [Reaction:R-ITR-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Ipomoea triloba [Reaction:R-NNU-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Nelumbo nucifera [Reaction:R-TSP-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Triticum spelta subsp. spelta [Reaction:R-BOL-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Brassica oleracea [Reaction:R-DEX-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Digitaria exilis [Reaction:R-HLP-1121539] a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP - Humulus lupulus var. lupulus
output	[SimpleEntity:R-ALL-1132205] 5,10-methylenetetrahydrofolate(2-) [cytosol] [SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol]
precedingEvent	[Reaction:R-OSA-1121174] Glycine hydroxymethyltransferase - Oryza sativa
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1121539
summation	[Summation:2871169] A 5,10-methylene-tetrahydrofolate is converted into a 5,10-m...

Referrals

(hasEvent)

[Pathway:R-OSA-1119617] Folate polyglutamylation I - Oryza sativa

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