Plant Reactome Pathway Database - Plant Reactome Pathway Database

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP

Stable Identifier

R-OSA-1121539

Type

Reaction

Species

Oryza sativa

Compartment

cytosol

Synonyms

RXN0-2921, biochemicalReaction6666

Locations in the PathwayBrowser

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Summation

A 5,10-methylene-tetrahydrofolate is converted into a 5,10-methylene-tetrahydrofolate by enzymatic activity of glycine hydroxymethyltransferase.

Participants

Input

Output

Participant Of

hasEvent

Folate polyglutamylation I

Catalyst Activity

Title

tetrahydrofolylpolyglutamate synthase activity of tetrahydrofolate synthase [cytosol]

Physical Entity

tetrahydrofolate synthase [cytosol]

Activity

tetrahydrofolylpolyglutamate synthase activity (0004326)

Orthologous Events

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Actinidia chinensis)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Aegilops tauschii)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Aegilops umbellulata)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Amborella trichopoda)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Ananas comosus)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Arabidopsis halleri)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Arabidopsis lyrata)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Arabidopsis thaliana)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Arachis duranensis)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Arachis hypogaea)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Arachis ipaensis)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Asparagus officinalis)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Avena sativa)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Beta vulgaris)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Brachypodium distachyon)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Brassica juncea)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Brassica napus)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Brassica oleracea)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Brassica rapa)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Cajanus cajan)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Camelina sativa)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Cannabis sativa)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Cannabis sativa subsp. indica)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Capsella rubella)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Capsicum annuum)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Chara braunii)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Chenopodium quinoa)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Chlamydomonas reinhardtii)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Cicer arietinum)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Citrullus lanatus)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Citrus clementina)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Citrus sinensis)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Coffea canephora)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Corchorus capsularis)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Corchorus olitorius)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Corymbia citriodora)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Cucumis melo)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Cucumis sativus)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Cynara cardunculus var. scolymus)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Daucus carota)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Digitaria exilis)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Dioscorea rotundata)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Echinochloa crus-galli)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Eragrostis curvula)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Eragrostis tef)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Erythranthe guttata)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Eucalyptus grandis)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Ficus carica)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Fragaria vesca)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Fraxinus excelsior (European ash))

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Glycine max)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Glycine soja)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Gossypium raimondii)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Helianthus annuus)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Hordeum vulgare)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Humulus lupulus)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Humulus lupulus var. lupulus)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Ipomoea triloba)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Jatropha curcas)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Juglans regia)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Lactuca sativa)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Lathyrus sativus)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Leersia perrieri)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Lolium perenne)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Lupinus angustifolius)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Malus domestica)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Manihot esculenta)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Marchantia polymorpha)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Medicago truncatula)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Musa acuminata)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Nelumbo nucifera)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Nicotiana attenuata)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Nymphaea colorata)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Olea europaea)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Olea europaea var. sylvestris)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Oryza australiensis)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Oryza barthii)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Oryza brachyantha)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Oryza glaberrima)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Oryza glumaepatula)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Oryza longistaminata)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Oryza meridionalis)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Oryza meyeriana var. granulata)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Oryza minuta)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Oryza nivara)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Oryza officinalis)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Oryza punctata)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Oryza rufipogon)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Oryza sativa Indica Group)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Ostreococcus lucimarinus)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Panicum hallii ("FIL2"))

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Panicum hallii var. hallii ("HAL2"))

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Papaver somniferum)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Phaseolus vulgaris)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Phoenix dactylifera)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Phyllostachys edulis)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Physcomitrella patens)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Picea abies)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Pinus taeda)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Pistacia vera)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Pisum sativum)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Populus trichocarpa)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Prunus avium)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Prunus persica)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Quercus lobata)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Quercus suber)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Rosa chinensis)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Saccharum spontaneum)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Salvia hispanica)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Secale cereale)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Selaginella moellendorffii)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Sesamum indicum)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Setaria italica)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Setaria viridis)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Solanum lycopersicum)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Solanum tuberosum)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Sorghum bicolor)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Synechocystis sp. PCC 6803)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Theobroma cacao)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Trifolium pratense)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Triticum aestivum)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Triticum dicoccoides)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Triticum spelta subsp. spelta)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Triticum timopheevii subsp. timopheevii)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Triticum turgidum)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Triticum urartu)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Vicia faba var. faba)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Vigna angularis)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Vigna radiata)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Vigna unguiculata)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Vitis vinifera)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Zea mays)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Zea mays ver5)

a 5,10-methylene-tetrahydrofolate+L-glutamate+ATP->a 5,10-methylene-tetrahydrofolate+phosphate+ADP (Zoysia japonica)

Cross References

RiceCyc

RXN0-2921

6.3.2.17