Plant Reactome Pathway Database - Plant Reactome Pathway Database

Schema > Reaction > Entries

Formation of L-Gln from L-Glu in cytosol

Go to Details

catalystActivity	[CatalystActivity:1118806] glutamine synthetase activity of glutamate-ammonia ligase [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:28131] EC:6.3.1.2 [DatabaseIdentifier:1134483] RiceCyc:GLUTAMINESYN-RXN
dbId	1121516
displayName	Formation of L-Gln from L-Glu in cytosol
eventOf	[Pathway:R-OSA-1119293] Glutamine biosynthesis I - Oryza sativa [Pathway:R-OSA-1119443] Ammonia assimilation cycle - Oryza sativa [Pathway:R-OSA-1119291] Nitrate assimilation - Oryza sativa
followingEvent	[Reaction:R-OSA-5603486] L-glutamine+2-oxaloglutarate+ 2 reduced ferredoxins->2 L-glutamate+2 oxidized ferredoxins - Oryza sativa [Reaction:R-OSA-5606381] glutamate synthesis (NADH dependent) plastidic - Oryza sativa
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-29404] L-Glu [cytosol] [SimpleEntity:R-ALL-29382] NH3 [cytosol]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	Formation of L-Gln from L-Glu in cytosol ammonia+L-glutamate+ATP->L-glutamine+ADP+phosphate cytosolic Glutamate--ammonia ligase Glutamine synthetase biochemicalReaction6978
orthologousEvent	[Reaction:R-CST-1121516] Formation of L-Gln from L-Glu in cytosol - Camelina sativa [Reaction:R-PVU-1121516] Formation of L-Gln from L-Glu in cytosol - Phaseolus vulgaris [Reaction:R-SMO-1121516] Formation of L-Gln from L-Glu in cytosol - Selaginella moellendorffii [Reaction:R-MAC-1121516] Formation of L-Gln from L-Glu in cytosol - Musa acuminata [Reaction:R-OME-1121516] Formation of L-Gln from L-Glu in cytosol - Oryza meridionalis [Reaction:R-COL-1121516] Formation of L-Gln from L-Glu in cytosol - Corchorus olitorius [Reaction:R-OBR-1121516] Formation of L-Gln from L-Glu in cytosol - Oryza brachyantha [Reaction:R-NNU-1121516] Formation of L-Gln from L-Glu in cytosol - Nelumbo nucifera [Reaction:R-PED-1121516] Formation of L-Gln from L-Glu in cytosol - Phyllostachys edulis [Reaction:R-PTI-1121516] Formation of L-Gln from L-Glu in cytosol - Populus trichocarpa [Reaction:R-PPA-1121516] Formation of L-Gln from L-Glu in cytosol - Physcomitrella patens [Reaction:R-ALY-1121516] Formation of L-Gln from L-Glu in cytosol - Arabidopsis lyrata [Reaction:R-OMI-1121516] Formation of L-Gln from L-Glu in cytosol - Oryza minuta [Reaction:R-PSO-1121516] Formation of L-Gln from L-Glu in cytosol - Papaver somniferum [Reaction:R-ECG-1121516] Formation of L-Gln from L-Glu in cytosol - Echinochloa crus-galli [Reaction:R-VAN-1121516] Formation of L-Gln from L-Glu in cytosol - Vigna angularis [Reaction:R-FEX-1121516] Formation of L-Gln from L-Glu in cytosol - Fraxinus excelsior (European ash) [Reaction:R-PSA-1121516] Formation of L-Gln from L-Glu in cytosol - Pisum sativum [Reaction:R-SVI-1121516] Formation of L-Gln from L-Glu in cytosol - Setaria viridis [Reaction:R-OKA-1121516] Formation of L-Gln from L-Glu in cytosol - Oryza sativa aus subgroup [Reaction:R-ZJA-1121516] Formation of L-Gln from L-Glu in cytosol - Zoysia japonica [Reaction:R-LPR-1121516] Formation of L-Gln from L-Glu in cytosol - Lolium perenne [Reaction:R-MTR-1121516] Formation of L-Gln from L-Glu in cytosol - Medicago truncatula [Reaction:R-NCO-1121516] Formation of L-Gln from L-Glu in cytosol - Nymphaea colorata [Reaction:R-CME-1121516] Formation of L-Gln from L-Glu in cytosol - Cyanidioschyzon merolae [Reaction:R-DEX-1121516] Formation of L-Gln from L-Glu in cytosol - Digitaria exilis [Reaction:R-MGU-1121516] Formation of L-Gln from L-Glu in cytosol - Erythranthe guttata [Reaction:R-CCD-1121516] Formation of L-Gln from L-Glu in cytosol - Cynara cardunculus var. scolymus [Reaction:R-ACO-1121516] Formation of L-Gln from L-Glu in cytosol - Ananas comosus [Reaction:R-CQI-1121516] Formation of L-Gln from L-Glu in cytosol - Chenopodium quinoa [Reaction:R-ATH-1121516] Formation of L-Gln from L-Glu in cytosol - Arabidopsis thaliana [Reaction:R-BJU-1121516] Formation of L-Gln from L-Glu in cytosol - Brassica juncea [Reaction:R-BDI-1121516] Formation of L-Gln from L-Glu in cytosol - Brachypodium distachyon [Reaction:R-CCL-1121516] Formation of L-Gln from L-Glu in cytosol - Citrus clementina [Reaction:R-CCN-1121516] Formation of L-Gln from L-Glu in cytosol - Coffea canephora [Reaction:R-VFA-1121516] Formation of L-Gln from L-Glu in cytosol - Vicia faba var. faba [Reaction:R-CSI-1121516] Formation of L-Gln from L-Glu in cytosol - Citrus sinensis [Reaction:R-TAE-1121516] Formation of L-Gln from L-Glu in cytosol - Triticum aestivum [Reaction:R-AUM-1121516] Formation of L-Gln from L-Glu in cytosol - Aegilops umbellulata [Reaction:R-HAN-1121516] Formation of L-Gln from L-Glu in cytosol - Helianthus annuus [Reaction:R-OGR-1121516] Formation of L-Gln from L-Glu in cytosol - Oryza meyeriana var. granulata [Reaction:R-CRE-1121516] Formation of L-Gln from L-Glu in cytosol - Chlamydomonas reinhardtii [Reaction:R-CSC-1121516] Formation of L-Gln from L-Glu in cytosol - Cannabis sativa [Reaction:R-OAU-1121516] Formation of L-Gln from L-Glu in cytosol - Oryza australiensis [Reaction:R-OGL-1121516] Formation of L-Gln from L-Glu in cytosol - Oryza glaberrima [Reaction:R-ADU-1121516] Formation of L-Gln from L-Glu in cytosol - Arachis duranensis [Reaction:R-OES-1121516] Formation of L-Gln from L-Glu in cytosol - Olea europaea var. sylvestris [Reaction:R-SBI-1121516] Formation of L-Gln from L-Glu in cytosol - Sorghum bicolor [Reaction:R-CCI-1121516] Formation of L-Gln from L-Glu in cytosol - Corymbia citriodora [Reaction:R-LPE-1121516] Formation of L-Gln from L-Glu in cytosol - Leersia perrieri [Reaction:R-BRA-1121516] Formation of L-Gln from L-Glu in cytosol - Brassica rapa [Reaction:R-ONI-1121516] Formation of L-Gln from L-Glu in cytosol - Oryza nivara [Reaction:R-PDA-1121516] Formation of L-Gln from L-Glu in cytosol - Phoenix dactylifera [Reaction:R-OBA-1121516] Formation of L-Gln from L-Glu in cytosol - Oryza barthii [Reaction:R-OGU-1121516] Formation of L-Gln from L-Glu in cytosol - Oryza glumaepatula [Reaction:R-ORU-1121516] Formation of L-Gln from L-Glu in cytosol - Oryza rufipogon [Reaction:R-TDI-1121516] Formation of L-Gln from L-Glu in cytosol - Triticum dicoccoides [Reaction:R-TPR-1121516] Formation of L-Gln from L-Glu in cytosol - Trifolium pratense [Reaction:R-MDO-1121516] Formation of L-Gln from L-Glu in cytosol - Malus domestica [Reaction:R-BNA-1121516] Formation of L-Gln from L-Glu in cytosol - Brassica napus [Reaction:R-MPO-1121516] Formation of L-Gln from L-Glu in cytosol - Marchantia polymorpha [Reaction:R-PPE-1121516] Formation of L-Gln from L-Glu in cytosol - Prunus persica [Reaction:R-ACH-1121516] Formation of L-Gln from L-Glu in cytosol - Actinidia chinensis [Reaction:R-GMA-1121516] Formation of L-Gln from L-Glu in cytosol - Glycine max [Reaction:R-GRA-1121516] Formation of L-Gln from L-Glu in cytosol - Gossypium raimondii [Reaction:R-PHA-1121516] Formation of L-Gln from L-Glu in cytosol - Panicum hallii ("FIL2") [Reaction:R-STU-1121516] Formation of L-Gln from L-Glu in cytosol - Solanum tuberosum [Reaction:R-NAT-1121516] Formation of L-Gln from L-Glu in cytosol - Nicotiana attenuata [Reaction:R-LSA-1121516] Formation of L-Gln from L-Glu in cytosol - Lactuca sativa [Reaction:R-SLY-1121516] Formation of L-Gln from L-Glu in cytosol - Solanum lycopersicum [Reaction:R-LST-1121516] Formation of L-Gln from L-Glu in cytosol - Lathyrus sativus [Reaction:R-HLH-1121516] Formation of L-Gln from L-Glu in cytosol - Humulus lupulus [Reaction:R-OEU-1121516] Formation of L-Gln from L-Glu in cytosol - Olea europaea [Reaction:R-TUR-1121516] Formation of L-Gln from L-Glu in cytosol - Triticum urartu [Reaction:R-PAV-1121516] Formation of L-Gln from L-Glu in cytosol - Prunus avium [Reaction:R-QSU-1121516] Formation of L-Gln from L-Glu in cytosol - Quercus suber [Reaction:R-OPU-1121516] Formation of L-Gln from L-Glu in cytosol - Oryza punctata [Reaction:R-SHI-1121516] Formation of L-Gln from L-Glu in cytosol - Salvia hispanica [Reaction:R-SIT-1121516] Formation of L-Gln from L-Glu in cytosol - Setaria italica [Reaction:R-ITR-1121516] Formation of L-Gln from L-Glu in cytosol - Ipomoea triloba [Reaction:R-CCR-1121516] Formation of L-Gln from L-Glu in cytosol - Chondrus crispus [Reaction:R-CRU-1121516] Formation of L-Gln from L-Glu in cytosol - Capsella rubella [Reaction:R-PAB-1121516] Formation of L-Gln from L-Glu in cytosol - Picea abies [Reaction:R-CBA-1121516] Formation of L-Gln from L-Glu in cytosol - Chara braunii [Reaction:R-OLO-1121516] Formation of L-Gln from L-Glu in cytosol - Oryza longistaminata [Reaction:R-CCP-1121516] Formation of L-Gln from L-Glu in cytosol - Corchorus capsularis [Reaction:R-ASA-1121516] Formation of L-Gln from L-Glu in cytosol - Avena sativa [Reaction:R-VUN-1121516] Formation of L-Gln from L-Glu in cytosol - Vigna unguiculata [Reaction:R-AHY-1121516] Formation of L-Gln from L-Glu in cytosol - Arachis hypogaea [Reaction:R-HVU-1121516] Formation of L-Gln from L-Glu in cytosol - Hordeum vulgare [Reaction:R-SCR-1121516] Formation of L-Gln from L-Glu in cytosol - Secale cereale [Reaction:R-RCH-1121516] Formation of L-Gln from L-Glu in cytosol - Rosa chinensis [Reaction:R-CSA-1121516] Formation of L-Gln from L-Glu in cytosol - Cucumis sativus [Reaction:R-LAN-1121516] Formation of L-Gln from L-Glu in cytosol - Lupinus angustifolius [Reaction:R-ECU-1121516] Formation of L-Gln from L-Glu in cytosol - Eragrostis curvula [Reaction:R-JCU-1121516] Formation of L-Gln from L-Glu in cytosol - Jatropha curcas [Reaction:R-PTA-1121516] Formation of L-Gln from L-Glu in cytosol - Pinus taeda [Reaction:R-SSP-1121516] Formation of L-Gln from L-Glu in cytosol - Saccharum spontaneum [Reaction:R-TTU-1121516] Formation of L-Gln from L-Glu in cytosol - Triticum turgidum [Reaction:R-JRE-1121516] Formation of L-Gln from L-Glu in cytosol - Juglans regia [Reaction:R-PHH-1121516] Formation of L-Gln from L-Glu in cytosol - Panicum hallii var. hallii ("HAL2") [Reaction:R-HLP-1121516] Formation of L-Gln from L-Glu in cytosol - Humulus lupulus var. lupulus [Reaction:R-ETE-1121516] Formation of L-Gln from L-Glu in cytosol - Eragrostis tef [Reaction:R-GSU-1121516] Formation of L-Gln from L-Glu in cytosol - Galdieria sulphuraria [Reaction:R-AHA-1121516] Formation of L-Gln from L-Glu in cytosol - Arabidopsis halleri [Reaction:R-CAR-1121516] Formation of L-Gln from L-Glu in cytosol - Cicer arietinum [Reaction:R-BVU-1121516] Formation of L-Gln from L-Glu in cytosol - Beta vulgaris [Reaction:R-VVN-1121516] Formation of L-Gln from L-Glu in cytosol - Vitis vinifera [Reaction:R-CSK-1121516] Formation of L-Gln from L-Glu in cytosol - Cannabis sativa subsp. indica [Reaction:R-ZMA-1121516] Formation of L-Gln from L-Glu in cytosol - Zea mays [Reaction:R-TSP-1121516] Formation of L-Gln from L-Glu in cytosol - Triticum spelta subsp. spelta [Reaction:R-ATA-1121516] Formation of L-Gln from L-Glu in cytosol - Aegilops tauschii [Reaction:R-PVE-1121516] Formation of L-Gln from L-Glu in cytosol - Pistacia vera [Reaction:R-CAN-1121516] Formation of L-Gln from L-Glu in cytosol - Capsicum annuum [Reaction:R-TTI-1121516] Formation of L-Gln from L-Glu in cytosol - Triticum timopheevii subsp. timopheevii [Reaction:R-CML-1121516] Formation of L-Gln from L-Glu in cytosol - Cucumis melo [Reaction:R-DRO-1121516] Formation of L-Gln from L-Glu in cytosol - Dioscorea rotundata [Reaction:R-FVE-1121516] Formation of L-Gln from L-Glu in cytosol - Fragaria vesca [Reaction:R-AOF-1121516] Formation of L-Gln from L-Glu in cytosol - Asparagus officinalis [Reaction:R-FCR-1121516] Formation of L-Gln from L-Glu in cytosol - Ficus carica [Reaction:R-OSI-1121516] Formation of L-Gln from L-Glu in cytosol - Oryza sativa Indica Group [Reaction:R-DCA-1121516] Formation of L-Gln from L-Glu in cytosol - Daucus carota [Reaction:R-CCA-1121516] Formation of L-Gln from L-Glu in cytosol - Cajanus cajan [Reaction:R-EGR-1121516] Formation of L-Gln from L-Glu in cytosol - Eucalyptus grandis [Reaction:R-AIP-1121516] Formation of L-Gln from L-Glu in cytosol - Arachis ipaensis [Reaction:R-VRA-1121516] Formation of L-Gln from L-Glu in cytosol - Vigna radiata [Reaction:R-SIN-1121516] Formation of L-Gln from L-Glu in cytosol - Sesamum indicum [Reaction:R-CLA-1121516] Formation of L-Gln from L-Glu in cytosol - Citrullus lanatus [Reaction:R-ATR-1121516] Formation of L-Gln from L-Glu in cytosol - Amborella trichopoda [Reaction:R-OOF-1121516] Formation of L-Gln from L-Glu in cytosol - Oryza officinalis [Reaction:R-QLO-1121516] Formation of L-Gln from L-Glu in cytosol - Quercus lobata [Reaction:R-ZMY-1121516] Formation of L-Gln from L-Glu in cytosol - Zea mays ver5 [Reaction:R-GSO-1121516] Formation of L-Gln from L-Glu in cytosol - Glycine soja [Reaction:R-TCA-1121516] Formation of L-Gln from L-Glu in cytosol - Theobroma cacao [Reaction:R-MES-1121516] Formation of L-Gln from L-Glu in cytosol - Manihot esculenta [Reaction:R-BOL-1121516] Formation of L-Gln from L-Glu in cytosol - Brassica oleracea
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-29472] L-Gln [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol]
precedingEvent	[Reaction:R-OSA-1120926] nitrite+a reduced ferredoxin->ammonia+H2O+an oxidized ferredoxin - Oryza sativa
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1121516
summation	[Summation:2851132] L-glutamate is converted to L-glutamine by enzymatic activit...

Referrals

(hasEvent)	[Pathway:R-OSA-1119293] Glutamine biosynthesis I - Oryza sativa [Pathway:R-OSA-1119291] Nitrate assimilation - Oryza sativa [Pathway:R-OSA-1119443] Ammonia assimilation cycle - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-5603486] L-glutamine+2-oxaloglutarate+ 2 reduced ferredoxins->2 L-glutamate+2 oxidized ferredoxins - Oryza sativa [Reaction:R-OSA-5606381] glutamate synthesis (NADH dependent) plastidic - Oryza sativa