Plant Reactome Pathway Database - Plant Reactome Pathway Database

Schema > Reaction > Entries

glutamate-5-semialdehyde dehydrogenase

Go to Details

catalystActivity	[CatalystActivity:1119161] glutamate-5-semialdehyde dehydrogenase activity of Glutamate 5-kinase/Glutamate-5-semialdehyde dehydrogenase (LOC_OS05G38150) [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:26755] EC:1.2.1.41 [DatabaseIdentifier:1143804] RiceCyc:GLUTSEMIALDEHYDROG-RXN
dbId	1121416
displayName	glutamate-5-semialdehyde dehydrogenase
eventOf	[Pathway:R-OSA-1119631] Proline biosynthesis I - Oryza sativa [Pathway:R-OSA-1119495] Citrulline biosynthesis - Oryza sativa
followingEvent	[Reaction:R-OSA-5633265] ornithine aminotransferase (L-glutamate-5-semialdehyde to L-ornithine) - Oryza sativa [Reaction:R-OSA-1120302] ornithine aminotransferase - Oryza sativa [Reaction:R-OSA-1120680] L-glutamate gamma-semialdehyde->H2O+pyrroline 5-carboxylate - Oryza sativa [Reaction:R-OSA-5633266] pyrroline 5-carboxylate + H2O + H+> L-glutamate gamma-semialdehyde - Oryza sativa
input	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-1132071] L-glutamate-5-phosphate [cytosol] [SimpleEntity:R-ALL-29364] NADPH [cytosol]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	glutamate-5-semialdehyde dehydrogenase Glutamyl-γ-semialdehyde dehydrogenase β-glutamylphosphate reductase γ-glutamylphosphate reductase biochemicalReaction83067
orthologousEvent	[Reaction:R-OAU-1121416] glutamate-5-semialdehyde dehydrogenase - Oryza australiensis [Reaction:R-VUN-1121416] glutamate-5-semialdehyde dehydrogenase - Vigna unguiculata [Reaction:R-HVU-1121416] glutamate-5-semialdehyde dehydrogenase - Hordeum vulgare [Reaction:R-CCN-1121416] glutamate-5-semialdehyde dehydrogenase - Coffea canephora [Reaction:R-SMO-1121416] glutamate-5-semialdehyde dehydrogenase - Selaginella moellendorffii [Reaction:R-LST-1121416] glutamate-5-semialdehyde dehydrogenase - Lathyrus sativus [Reaction:R-SCR-1121416] glutamate-5-semialdehyde dehydrogenase - Secale cereale [Reaction:R-BVU-1121416] glutamate-5-semialdehyde dehydrogenase - Beta vulgaris [Reaction:R-COL-1121416] glutamate-5-semialdehyde dehydrogenase - Corchorus olitorius [Reaction:R-NCO-1121416] glutamate-5-semialdehyde dehydrogenase - Nymphaea colorata [Reaction:R-AIP-1121416] glutamate-5-semialdehyde dehydrogenase - Arachis ipaensis [Reaction:R-OOF-1121416] glutamate-5-semialdehyde dehydrogenase - Oryza officinalis [Reaction:R-PDA-1121416] glutamate-5-semialdehyde dehydrogenase - Phoenix dactylifera [Reaction:R-PSA-1121416] glutamate-5-semialdehyde dehydrogenase - Pisum sativum [Reaction:R-CRE-1121416] glutamate-5-semialdehyde dehydrogenase - Chlamydomonas reinhardtii [Reaction:R-AOF-1121416] glutamate-5-semialdehyde dehydrogenase - Asparagus officinalis [Reaction:R-AUM-1121416] glutamate-5-semialdehyde dehydrogenase - Aegilops umbellulata [Reaction:R-MPO-1121416] glutamate-5-semialdehyde dehydrogenase - Marchantia polymorpha [Reaction:R-ONI-1121416] glutamate-5-semialdehyde dehydrogenase - Oryza nivara [Reaction:R-SVI-1121416] glutamate-5-semialdehyde dehydrogenase - Setaria viridis [Reaction:R-ATH-1121416] glutamate-5-semialdehyde dehydrogenase - Arabidopsis thaliana [Reaction:R-CCA-1121416] glutamate-5-semialdehyde dehydrogenase - Cajanus cajan [Reaction:R-ECG-1121416] glutamate-5-semialdehyde dehydrogenase - Echinochloa crus-galli [Reaction:R-JRE-1121416] glutamate-5-semialdehyde dehydrogenase - Juglans regia [Reaction:R-CQI-1121416] glutamate-5-semialdehyde dehydrogenase - Chenopodium quinoa [Reaction:R-PSO-1121416] glutamate-5-semialdehyde dehydrogenase - Papaver somniferum [Reaction:R-ALY-1121416] glutamate-5-semialdehyde dehydrogenase - Arabidopsis lyrata [Reaction:R-ATA-1121416] glutamate-5-semialdehyde dehydrogenase - Aegilops tauschii [Reaction:R-GRA-1121416] glutamate-5-semialdehyde dehydrogenase - Gossypium raimondii [Reaction:R-SHI-1121416] glutamate-5-semialdehyde dehydrogenase - Salvia hispanica [Reaction:R-LAN-1121416] glutamate-5-semialdehyde dehydrogenase - Lupinus angustifolius [Reaction:R-PTA-1121416] glutamate-5-semialdehyde dehydrogenase - Pinus taeda [Reaction:R-AHA-1121416] glutamate-5-semialdehyde dehydrogenase - Arabidopsis halleri [Reaction:R-CLA-1121416] glutamate-5-semialdehyde dehydrogenase - Citrullus lanatus [Reaction:R-TSP-1121416] glutamate-5-semialdehyde dehydrogenase - Triticum spelta subsp. spelta [Reaction:R-ACH-1121416] glutamate-5-semialdehyde dehydrogenase - Actinidia chinensis [Reaction:R-FVE-1121416] glutamate-5-semialdehyde dehydrogenase - Fragaria vesca [Reaction:R-PVE-1121416] glutamate-5-semialdehyde dehydrogenase - Pistacia vera [Reaction:R-ETE-1121416] glutamate-5-semialdehyde dehydrogenase - Eragrostis tef [Reaction:R-PHA-1121416] glutamate-5-semialdehyde dehydrogenase - Panicum hallii ("FIL2") [Reaction:R-GSU-1121416] glutamate-5-semialdehyde dehydrogenase - Galdieria sulphuraria [Reaction:R-HLH-1121416] glutamate-5-semialdehyde dehydrogenase - Humulus lupulus [Reaction:R-ZMY-1121416] glutamate-5-semialdehyde dehydrogenase - Zea mays ver5 [Reaction:R-TDI-1121416] glutamate-5-semialdehyde dehydrogenase - Triticum dicoccoides [Reaction:R-PVU-1121416] glutamate-5-semialdehyde dehydrogenase - Phaseolus vulgaris [Reaction:R-SSP-1121416] glutamate-5-semialdehyde dehydrogenase - Saccharum spontaneum [Reaction:R-CCP-1121416] glutamate-5-semialdehyde dehydrogenase - Corchorus capsularis [Reaction:R-DEX-1121416] glutamate-5-semialdehyde dehydrogenase - Digitaria exilis [Reaction:R-ZJA-1121416] glutamate-5-semialdehyde dehydrogenase - Zoysia japonica [Reaction:R-RCH-1121416] glutamate-5-semialdehyde dehydrogenase - Rosa chinensis [Reaction:R-OLO-1121416] glutamate-5-semialdehyde dehydrogenase - Oryza longistaminata [Reaction:R-OBA-1121416] glutamate-5-semialdehyde dehydrogenase - Oryza barthii [Reaction:R-BOL-1121416] glutamate-5-semialdehyde dehydrogenase - Brassica oleracea [Reaction:R-HAN-1121416] glutamate-5-semialdehyde dehydrogenase - Helianthus annuus [Reaction:R-CSC-1121416] glutamate-5-semialdehyde dehydrogenase - Cannabis sativa [Reaction:R-OGR-1121416] glutamate-5-semialdehyde dehydrogenase - Oryza meyeriana var. granulata [Reaction:R-DRO-1121416] glutamate-5-semialdehyde dehydrogenase - Dioscorea rotundata [Reaction:R-SBI-1121416] glutamate-5-semialdehyde dehydrogenase - Sorghum bicolor [Reaction:R-LPE-1121416] glutamate-5-semialdehyde dehydrogenase - Leersia perrieri [Reaction:R-OME-1121416] glutamate-5-semialdehyde dehydrogenase - Oryza meridionalis [Reaction:R-TPR-1121416] glutamate-5-semialdehyde dehydrogenase - Trifolium pratense [Reaction:R-TUR-1121416] glutamate-5-semialdehyde dehydrogenase - Triticum urartu [Reaction:R-PHH-1121416] glutamate-5-semialdehyde dehydrogenase - Panicum hallii var. hallii ("HAL2") [Reaction:R-CSK-1121416] glutamate-5-semialdehyde dehydrogenase - Cannabis sativa subsp. indica [Reaction:R-GSO-1121416] glutamate-5-semialdehyde dehydrogenase - Glycine soja [Reaction:R-CST-1121416] glutamate-5-semialdehyde dehydrogenase - Camelina sativa [Reaction:R-OGL-1121416] glutamate-5-semialdehyde dehydrogenase - Oryza glaberrima [Reaction:R-ADU-1121416] glutamate-5-semialdehyde dehydrogenase - Arachis duranensis [Reaction:R-MDO-1121416] glutamate-5-semialdehyde dehydrogenase - Malus domestica [Reaction:R-ZMA-1121416] glutamate-5-semialdehyde dehydrogenase - Zea mays [Reaction:R-MTR-1121416] glutamate-5-semialdehyde dehydrogenase - Medicago truncatula [Reaction:R-DCA-1121416] glutamate-5-semialdehyde dehydrogenase - Daucus carota [Reaction:R-CSI-1121416] glutamate-5-semialdehyde dehydrogenase - Citrus sinensis [Reaction:R-CAR-1121416] glutamate-5-semialdehyde dehydrogenase - Cicer arietinum [Reaction:R-PPA-1121416] glutamate-5-semialdehyde dehydrogenase - Physcomitrella patens [Reaction:R-SIN-1121416] glutamate-5-semialdehyde dehydrogenase - Sesamum indicum [Reaction:R-SPC-1121416] glutamate-5-semialdehyde dehydrogenase - Synechocystis sp. PCC 6803 [Reaction:R-CCR-1121416] glutamate-5-semialdehyde dehydrogenase - Chondrus crispus [Reaction:R-ORU-1121416] glutamate-5-semialdehyde dehydrogenase - Oryza rufipogon [Reaction:R-OLU-1121416] glutamate-5-semialdehyde dehydrogenase - Ostreococcus lucimarinus [Reaction:R-CCL-1121416] glutamate-5-semialdehyde dehydrogenase - Citrus clementina [Reaction:R-LSA-1121416] glutamate-5-semialdehyde dehydrogenase - Lactuca sativa [Reaction:R-ASA-1121416] glutamate-5-semialdehyde dehydrogenase - Avena sativa [Reaction:R-TTU-1121416] glutamate-5-semialdehyde dehydrogenase - Triticum turgidum [Reaction:R-QLO-1121416] glutamate-5-semialdehyde dehydrogenase - Quercus lobata [Reaction:R-OMI-1121416] glutamate-5-semialdehyde dehydrogenase - Oryza minuta [Reaction:R-OBR-1121416] glutamate-5-semialdehyde dehydrogenase - Oryza brachyantha [Reaction:R-OPU-1121416] glutamate-5-semialdehyde dehydrogenase - Oryza punctata [Reaction:R-SIT-1121416] glutamate-5-semialdehyde dehydrogenase - Setaria italica [Reaction:R-CBA-1121416] glutamate-5-semialdehyde dehydrogenase - Chara braunii [Reaction:R-BNA-1121416] glutamate-5-semialdehyde dehydrogenase - Brassica napus [Reaction:R-PAB-1121416] glutamate-5-semialdehyde dehydrogenase - Picea abies [Reaction:R-PAV-1121416] glutamate-5-semialdehyde dehydrogenase - Prunus avium [Reaction:R-PPE-1121416] glutamate-5-semialdehyde dehydrogenase - Prunus persica [Reaction:R-LPR-1121416] glutamate-5-semialdehyde dehydrogenase - Lolium perenne [Reaction:R-VAN-1121416] glutamate-5-semialdehyde dehydrogenase - Vigna angularis [Reaction:R-MGU-1121416] glutamate-5-semialdehyde dehydrogenase - Erythranthe guttata [Reaction:R-CCD-1121416] glutamate-5-semialdehyde dehydrogenase - Cynara cardunculus var. scolymus [Reaction:R-BJU-1121416] glutamate-5-semialdehyde dehydrogenase - Brassica juncea [Reaction:R-BDI-1121416] glutamate-5-semialdehyde dehydrogenase - Brachypodium distachyon [Reaction:R-HLP-1121416] glutamate-5-semialdehyde dehydrogenase - Humulus lupulus var. lupulus [Reaction:R-CML-1121416] glutamate-5-semialdehyde dehydrogenase - Cucumis melo [Reaction:R-CRU-1121416] glutamate-5-semialdehyde dehydrogenase - Capsella rubella [Reaction:R-TCA-1121416] glutamate-5-semialdehyde dehydrogenase - Theobroma cacao [Reaction:R-CSA-1121416] glutamate-5-semialdehyde dehydrogenase - Cucumis sativus [Reaction:R-PED-1121416] glutamate-5-semialdehyde dehydrogenase - Phyllostachys edulis [Reaction:R-CME-1121416] glutamate-5-semialdehyde dehydrogenase - Cyanidioschyzon merolae [Reaction:R-TAE-1121416] glutamate-5-semialdehyde dehydrogenase - Triticum aestivum [Reaction:R-GMA-1121416] glutamate-5-semialdehyde dehydrogenase - Glycine max [Reaction:R-TTI-1121416] glutamate-5-semialdehyde dehydrogenase - Triticum timopheevii subsp. timopheevii [Reaction:R-ATR-1121416] glutamate-5-semialdehyde dehydrogenase - Amborella trichopoda [Reaction:R-ECU-1121416] glutamate-5-semialdehyde dehydrogenase - Eragrostis curvula [Reaction:R-VRA-1121416] glutamate-5-semialdehyde dehydrogenase - Vigna radiata [Reaction:R-VFA-1121416] glutamate-5-semialdehyde dehydrogenase - Vicia faba var. faba [Reaction:R-OSI-1121416] glutamate-5-semialdehyde dehydrogenase - Oryza sativa Indica Group [Reaction:R-NNU-1121416] glutamate-5-semialdehyde dehydrogenase - Nelumbo nucifera [Reaction:R-OGU-1121416] glutamate-5-semialdehyde dehydrogenase - Oryza glumaepatula [Reaction:R-QSU-1121416] glutamate-5-semialdehyde dehydrogenase - Quercus suber [Reaction:R-BRA-1121416] glutamate-5-semialdehyde dehydrogenase - Brassica rapa [Reaction:R-AHY-1121416] glutamate-5-semialdehyde dehydrogenase - Arachis hypogaea [Reaction:R-MAC-1121416] glutamate-5-semialdehyde dehydrogenase - Musa acuminata
output	[SimpleEntity:R-ALL-1131815] L-Glu5S [cytosol] [SimpleEntity:R-ALL-29366] NADP+ [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol]
precedingEvent	[Reaction:R-OSA-1120144] glutamate 5-kinase - Oryza sativa
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1121416
summation	[Summation:2885056] L-glutamate-5-phosphate is converted to L-glutamate gamma-se...

Referrals

(hasEvent)	[Pathway:R-OSA-1119631] Proline biosynthesis I - Oryza sativa [Pathway:R-OSA-1119495] Citrulline biosynthesis - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-5633266] pyrroline 5-carboxylate + H2O + H+> L-glutamate gamma-semialdehyde - Oryza sativa [Reaction:R-OSA-5633265] ornithine aminotransferase (L-glutamate-5-semialdehyde to L-ornithine) - Oryza sativa [Reaction:R-OSA-1120302] ornithine aminotransferase - Oryza sativa [Reaction:R-OSA-1120680] L-glutamate gamma-semialdehyde->H2O+pyrroline 5-carboxylate - Oryza sativa