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glutamate-5-semialdehyde dehydrogenase

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catalystActivity	[CatalystActivity:11301120] glutamate-5-semialdehyde dehydrogenase activity of Glutamate 5-kinase/Glutamate-5-semialdehyde dehydrogenase (LOC_OS05G38150) [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:11292069] Elser, Justin, 2025-03-26
dbId	11301122
displayName	glutamate-5-semialdehyde dehydrogenase
eventOf	[Pathway:R-ECG-1119631] Proline biosynthesis I - Echinochloa crus-galli [Pathway:R-ECG-1119495] Citrulline biosynthesis - Echinochloa crus-galli
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Reaction:R-ECG-1120302] ornithine aminotransferase - Echinochloa crus-galli [Reaction:R-ECG-5633265] ornithine aminotransferase (L-glutamate-5-semialdehyde to L-ornithine) - Echinochloa crus-galli
inferredFrom	[Reaction:R-OSA-1121416] glutamate-5-semialdehyde dehydrogenase - Oryza sativa
input	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-1132071] L-glutamate-5-phosphate [cytosol] [SimpleEntity:R-ALL-29364] NADPH [cytosol]
isInDisease	false
isInferred	true
name	glutamate-5-semialdehyde dehydrogenase Glutamyl-γ-semialdehyde dehydrogenase β-glutamylphosphate reductase γ-glutamylphosphate reductase biochemicalReaction83067
output	[SimpleEntity:R-ALL-1131815] L-Glu5S [cytosol] [SimpleEntity:R-ALL-29366] NADP+ [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol]
precedingEvent	[Reaction:R-ECG-1120144] glutamate 5-kinase - Echinochloa crus-galli
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9823402] Echinochloa crus-galli
stId	R-ECG-1121416
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

Referrals

(hasEvent)	[Pathway:R-ECG-1119631] Proline biosynthesis I - Echinochloa crus-galli [Pathway:R-ECG-1119495] Citrulline biosynthesis - Echinochloa crus-galli
(precedingEvent)	[Reaction:R-ECG-5633265] ornithine aminotransferase (L-glutamate-5-semialdehyde to L-ornithine) - Echinochloa crus-galli [Reaction:R-ECG-1120302] ornithine aminotransferase - Echinochloa crus-galli
(inferredTo)	[Reaction:R-OSA-1121416] glutamate-5-semialdehyde dehydrogenase - Oryza sativa