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2-dehydropantoate 2-reductase

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catalystActivity	[CatalystActivity:1118875] 2-dehydropantoate 2-reductase activity of 2-dehydropantoate 2-reductase [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:26510] EC:1.1.1.169 [DatabaseIdentifier:1142576] RiceCyc:2-DEHYDROPANTOATE-REDUCT-RXN
dbId	1121249
displayName	2-dehydropantoate 2-reductase
eventOf	[Pathway:R-OSA-1119544] Pantothenate biosynthesis II - Oryza sativa [Pathway:R-OSA-1119496] Pantothenate biosynthesis I - Oryza sativa
followingEvent	[Reaction:R-OSA-1120902] Pantoate--beta-alanine ligase - Oryza sativa
input	[SimpleEntity:R-ALL-1131524] 2-dehydropantoate [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-29364] NADPH [cytosol]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	2-dehydropantoate 2-reductase KPA reductase Ketopantoic acid reductase Ketopantoate reductase biochemicalReaction94388
orthologousEvent	[Reaction:R-CLA-1121249] 2-dehydropantoate 2-reductase - Citrullus lanatus [Reaction:R-CSC-1121249] 2-dehydropantoate 2-reductase - Cannabis sativa [Reaction:R-TSP-1121249] 2-dehydropantoate 2-reductase - Triticum spelta subsp. spelta [Reaction:R-PAB-1121249] 2-dehydropantoate 2-reductase - Picea abies [Reaction:R-CAR-1121249] 2-dehydropantoate 2-reductase - Cicer arietinum [Reaction:R-CQI-1121249] 2-dehydropantoate 2-reductase - Chenopodium quinoa [Reaction:R-ASA-1121249] 2-dehydropantoate 2-reductase - Avena sativa [Reaction:R-ADU-1121249] 2-dehydropantoate 2-reductase - Arachis duranensis [Reaction:R-ZJA-1121249] 2-dehydropantoate 2-reductase - Zoysia japonica [Reaction:R-OGU-1121249] 2-dehydropantoate 2-reductase - Oryza glumaepatula [Reaction:R-OMI-1121249] 2-dehydropantoate 2-reductase - Oryza minuta [Reaction:R-TUR-1121249] 2-dehydropantoate 2-reductase - Triticum urartu [Reaction:R-CSK-1121249] 2-dehydropantoate 2-reductase - Cannabis sativa subsp. indica [Reaction:R-COL-1121249] 2-dehydropantoate 2-reductase - Corchorus olitorius [Reaction:R-FVE-1121249] 2-dehydropantoate 2-reductase - Fragaria vesca [Reaction:R-HLP-1121249] 2-dehydropantoate 2-reductase - Humulus lupulus var. lupulus [Reaction:R-OLO-1121249] 2-dehydropantoate 2-reductase - Oryza longistaminata [Reaction:R-PTA-1121249] 2-dehydropantoate 2-reductase - Pinus taeda [Reaction:R-OAU-1121249] 2-dehydropantoate 2-reductase - Oryza australiensis [Reaction:R-SHI-1121249] 2-dehydropantoate 2-reductase - Salvia hispanica [Reaction:R-PDA-1121249] 2-dehydropantoate 2-reductase - Phoenix dactylifera [Reaction:R-MGU-1121249] 2-dehydropantoate 2-reductase - Erythranthe guttata [Reaction:R-OOF-1121249] 2-dehydropantoate 2-reductase - Oryza officinalis [Reaction:R-OME-1121249] 2-dehydropantoate 2-reductase - Oryza meridionalis [Reaction:R-ONI-1121249] 2-dehydropantoate 2-reductase - Oryza nivara [Reaction:R-PED-1121249] 2-dehydropantoate 2-reductase - Phyllostachys edulis [Reaction:R-OSI-1121249] 2-dehydropantoate 2-reductase - Oryza sativa Indica Group [Reaction:R-CRU-1121249] 2-dehydropantoate 2-reductase - Capsella rubella [Reaction:R-AUM-1121249] 2-dehydropantoate 2-reductase - Aegilops umbellulata [Reaction:R-HLH-1121249] 2-dehydropantoate 2-reductase - Humulus lupulus [Reaction:R-OGR-1121249] 2-dehydropantoate 2-reductase - Oryza meyeriana var. granulata [Reaction:R-SLY-1121249] 2-dehydropantoate 2-reductase - Solanum lycopersicum [Reaction:R-TTI-1121249] 2-dehydropantoate 2-reductase - Triticum timopheevii subsp. timopheevii [Reaction:R-CSI-1121249] 2-dehydropantoate 2-reductase - Citrus sinensis
output	[SimpleEntity:R-ALL-1131880] L-pantoate [cytosol] [SimpleEntity:R-ALL-29366] NADP+ [cytosol]
precedingEvent	[Reaction:R-OSA-1119703] 3-methyl-2-oxobutanoate hydroxymethyltransferase - Oryza sativa
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1121249
summation	[Summation:2871773] 2-dehydropantoate is converted to L-pantoate by enzymatic ac...

Referrals

(hasEvent)	[Pathway:R-OSA-1119544] Pantothenate biosynthesis II - Oryza sativa [Pathway:R-OSA-1119496] Pantothenate biosynthesis I - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-1120902] Pantoate--beta-alanine ligase - Oryza sativa