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4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase

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catalystActivity	[CatalystActivity:1119205] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity of GHMP kinases ATP-binding protein (LOC_OS01G58790.1) [plastid stroma]
compartment	[Compartment:1141] plastid stroma
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:1154443] EC-NUMBER:2.7.1.148 [DatabaseIdentifier:1140435] RiceCyc:2.7.1.148-RXN
dbId	1121196
displayName	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase
eventOf	[Pathway:R-OSA-1119464] Methylerythritol phosphate pathway - Oryza sativa
followingEvent	[Reaction:R-OSA-1120374] 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase - Oryza sativa
input	[SimpleEntity:R-ALL-4723657] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol [plastid stroma] [SimpleEntity:R-ALL-1168674] ATP [plastid stroma]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase CDP-ME kinase CMK biochemicalReaction60158
orthologousEvent	[Reaction:R-MTR-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Medicago truncatula [Reaction:R-LST-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Lathyrus sativus [Reaction:R-ETE-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Eragrostis tef [Reaction:R-FEX-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Fraxinus excelsior (European ash) [Reaction:R-STU-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Solanum tuberosum [Reaction:R-PPE-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Prunus persica [Reaction:R-PED-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Phyllostachys edulis [Reaction:R-BNA-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Brassica napus [Reaction:R-PHH-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Panicum hallii var. hallii ("HAL2") [Reaction:R-ZMY-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Zea mays ver5 [Reaction:R-ORU-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Oryza rufipogon [Reaction:R-GSO-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Glycine soja [Reaction:R-DEX-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Digitaria exilis [Reaction:R-CCN-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Coffea canephora [Reaction:R-ECG-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Echinochloa crus-galli [Reaction:R-MDO-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Malus domestica [Reaction:R-LAN-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Lupinus angustifolius [Reaction:R-OBR-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Oryza brachyantha [Reaction:R-CCR-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Chondrus crispus [Reaction:R-TDI-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Triticum dicoccoides [Reaction:R-OLO-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Oryza longistaminata [Reaction:R-CAR-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Cicer arietinum [Reaction:R-JCU-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Jatropha curcas [Reaction:R-CML-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Cucumis melo [Reaction:R-HLH-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Humulus lupulus [Reaction:R-SHI-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Salvia hispanica [Reaction:R-ASA-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Avena sativa [Reaction:R-FCR-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Ficus carica [Reaction:R-ZMA-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Zea mays [Reaction:R-TPR-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Trifolium pratense [Reaction:R-TCA-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Theobroma cacao [Reaction:R-OPU-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Oryza punctata [Reaction:R-SMO-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Selaginella moellendorffii [Reaction:R-ACO-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Ananas comosus [Reaction:R-AHY-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Arachis hypogaea [Reaction:R-HLP-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Humulus lupulus var. lupulus [Reaction:R-ZJA-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Zoysia japonica [Reaction:R-ACH-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Actinidia chinensis [Reaction:R-ITR-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Ipomoea triloba [Reaction:R-CQI-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Chenopodium quinoa [Reaction:R-ECU-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Eragrostis curvula [Reaction:R-LSA-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Lactuca sativa [Reaction:R-SPC-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Synechocystis sp. PCC 6803 [Reaction:R-OGL-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Oryza glaberrima [Reaction:R-PTA-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Pinus taeda [Reaction:R-QSU-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Quercus suber [Reaction:R-OES-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Olea europaea var. sylvestris [Reaction:R-CSK-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Cannabis sativa subsp. indica [Reaction:R-PSA-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Pisum sativum [Reaction:R-GRA-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Gossypium raimondii [Reaction:R-JRE-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Juglans regia [Reaction:R-PAV-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Prunus avium [Reaction:R-OGU-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Oryza glumaepatula [Reaction:R-GSU-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Galdieria sulphuraria [Reaction:R-RCH-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Rosa chinensis [Reaction:R-OBA-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Oryza barthii [Reaction:R-DRO-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Dioscorea rotundata [Reaction:R-TTI-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Triticum timopheevii subsp. timopheevii [Reaction:R-QLO-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Quercus lobata [Reaction:R-OME-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Oryza meridionalis [Reaction:R-HVU-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Hordeum vulgare [Reaction:R-CRU-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Capsella rubella [Reaction:R-BRA-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Brassica rapa [Reaction:R-OMI-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Oryza minuta [Reaction:R-SVI-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Setaria viridis [Reaction:R-ATA-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Aegilops tauschii [Reaction:R-BVU-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Beta vulgaris [Reaction:R-AOF-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Asparagus officinalis [Reaction:R-BDI-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Brachypodium distachyon [Reaction:R-VVN-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Vitis vinifera [Reaction:R-SCR-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Secale cereale [Reaction:R-CSA-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Cucumis sativus [Reaction:R-CCI-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Corymbia citriodora [Reaction:R-VUN-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Vigna unguiculata [Reaction:R-ATH-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Arabidopsis thaliana [Reaction:R-PPA-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Physcomitrella patens [Reaction:R-HAN-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Helianthus annuus [Reaction:R-CLA-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Citrullus lanatus [Reaction:R-CCP-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Corchorus capsularis [Reaction:R-MAC-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Musa acuminata [Reaction:R-PVE-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Pistacia vera [Reaction:R-AUM-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Aegilops umbellulata [Reaction:R-OEU-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Olea europaea [Reaction:R-SLY-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Solanum lycopersicum [Reaction:R-ADU-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Arachis duranensis [Reaction:R-CBA-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Chara braunii [Reaction:R-LPR-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Lolium perenne [Reaction:R-SBI-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Sorghum bicolor [Reaction:R-MPO-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Marchantia polymorpha [Reaction:R-NAT-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Nicotiana attenuata [Reaction:R-CCL-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Citrus clementina [Reaction:R-NCO-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Nymphaea colorata [Reaction:R-TAE-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Triticum aestivum [Reaction:R-OSI-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Oryza sativa Indica Group [Reaction:R-CCA-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Cajanus cajan [Reaction:R-CSC-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Cannabis sativa [Reaction:R-FVE-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Fragaria vesca [Reaction:R-NNU-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Nelumbo nucifera [Reaction:R-PAB-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Picea abies [Reaction:R-OOF-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Oryza officinalis [Reaction:R-VFA-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Vicia faba var. faba [Reaction:R-BJU-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Brassica juncea [Reaction:R-PHA-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Panicum hallii ("FIL2") [Reaction:R-CCD-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Cynara cardunculus var. scolymus [Reaction:R-MES-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Manihot esculenta [Reaction:R-PVU-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Phaseolus vulgaris [Reaction:R-AHA-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Arabidopsis halleri [Reaction:R-MGU-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Erythranthe guttata [Reaction:R-OAU-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Oryza australiensis [Reaction:R-PDA-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Phoenix dactylifera [Reaction:R-EGR-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Eucalyptus grandis [Reaction:R-OLU-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Ostreococcus lucimarinus [Reaction:R-BOL-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Brassica oleracea [Reaction:R-TTU-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Triticum turgidum [Reaction:R-AIP-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Arachis ipaensis [Reaction:R-DCA-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Daucus carota [Reaction:R-ALY-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Arabidopsis lyrata [Reaction:R-ONI-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Oryza nivara [Reaction:R-GMA-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Glycine max [Reaction:R-PTI-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Populus trichocarpa [Reaction:R-CME-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Cyanidioschyzon merolae [Reaction:R-CRE-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Chlamydomonas reinhardtii [Reaction:R-OKA-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Oryza sativa aus subgroup [Reaction:R-TSP-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Triticum spelta subsp. spelta [Reaction:R-ATR-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Amborella trichopoda [Reaction:R-OGR-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Oryza meyeriana var. granulata [Reaction:R-CST-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Camelina sativa [Reaction:R-TUR-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Triticum urartu [Reaction:R-CSI-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Citrus sinensis [Reaction:R-SIT-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Setaria italica [Reaction:R-CAN-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Capsicum annuum [Reaction:R-VAN-1121196] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - Vigna angularis
output	[SimpleEntity:R-ALL-1131978] 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol [plastid stroma] [SimpleEntity:R-ALL-1168667] ADP [plastid stroma]
precedingEvent	[Reaction:R-OSA-1121571] 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase - Oryza sativa
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1121196
summation	[Summation:4723694] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol is convert...

Referrals

(hasEvent)	[Pathway:R-OSA-1119464] Methylerythritol phosphate pathway - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-1120374] 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase - Oryza sativa