Plant Reactome Pathway Database - Plant Reactome Pathway Database

Schema > Reaction > Entries

tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2

Go to Details

catalystActivity	[CatalystActivity:1118620] oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen of Tryptamine 5-hydroxylase [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:1154278] EC-NUMBER:1.14.13.- [DatabaseIdentifier:1148676] RiceCyc:RXN-8707
dbId	1121159
displayName	tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2
eventOf	[Pathway:R-OSA-1119344] Hydroxycinnamic acid serotonin amides biosynthesis - Oryza sativa
followingEvent	[Reaction:R-OSA-1120840] 4-coumaroyl-CoA+serotonin->H++p-coumaroylserotonin+coenzyme A - Oryza sativa [Reaction:R-OSA-1119798] serotonin+caffeoyl-CoA->H++caffeoylserotonin+coenzyme A - Oryza sativa [Reaction:R-OSA-1119839] feruloyl-CoA+serotonin->H++feruloylserotonin+coenzyme A - Oryza sativa [Reaction:R-OSA-1120063] serotonin+(E)-cinnamoyl-CoA->H++cinnamoylserotonin+coenzyme A - Oryza sativa
input	[SimpleEntity:R-ALL-70106] H+ [cytosol] [DefinedSet:R-ALL-428206] NAD(P)H [cytosol] [SimpleEntity:R-ALL-29368] O2 [cytosol] [SimpleEntity:R-ALL-1132116] tryptamine [cytosol]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11507626] Elser, Justin, 2025-03-27
name	tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 RXN-8707 biochemicalReaction85724
orthologousEvent	[Reaction:R-ZMY-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Zea mays ver5 [Reaction:R-OKA-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Oryza sativa aus subgroup [Reaction:R-FVE-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Fragaria vesca [Reaction:R-OAU-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Oryza australiensis [Reaction:R-CSI-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Citrus sinensis [Reaction:R-LPE-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Leersia perrieri [Reaction:R-SIT-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Setaria italica [Reaction:R-PDA-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Phoenix dactylifera [Reaction:R-ZJA-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Zoysia japonica [Reaction:R-ADU-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Arachis duranensis [Reaction:R-NNU-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Nelumbo nucifera [Reaction:R-OGL-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Oryza glaberrima [Reaction:R-HLH-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Humulus lupulus [Reaction:R-OMI-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Oryza minuta [Reaction:R-CRU-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Capsella rubella [Reaction:R-PAB-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Picea abies [Reaction:R-JCU-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Jatropha curcas [Reaction:R-COL-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Corchorus olitorius [Reaction:R-MGU-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Erythranthe guttata [Reaction:R-HLP-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Humulus lupulus var. lupulus [Reaction:R-SBI-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Sorghum bicolor [Reaction:R-CLA-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Citrullus lanatus [Reaction:R-CSK-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Cannabis sativa subsp. indica [Reaction:R-ASA-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Avena sativa [Reaction:R-AUM-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Aegilops umbellulata [Reaction:R-PED-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Phyllostachys edulis [Reaction:R-CAR-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Cicer arietinum [Reaction:R-OGR-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Oryza meyeriana var. granulata [Reaction:R-PTA-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Pinus taeda [Reaction:R-OME-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Oryza meridionalis [Reaction:R-TTU-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Triticum turgidum [Reaction:R-OOF-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Oryza officinalis [Reaction:R-TTI-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Triticum timopheevii subsp. timopheevii [Reaction:R-AIP-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Arachis ipaensis
output	[SimpleEntity:R-ALL-209914] 5HT [cytosol] [SimpleEntity:R-ALL-1131974] H2 [cytosol] [DefinedSet:R-ALL-428218] NAD(P)+ [cytosol]
precedingEvent	[Reaction:R-OSA-1121156] Aromatic-L-amino-acid decarboxylase - Oryza sativa
reviewed	[InstanceEdit:2879026] Dharmawardhana, DP, 2012-12-19
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1121159
summation	[Summation:2879048] Tryptamine is converted into serotonin by enzymatic activity...

Referrals

(hasEvent)	[Pathway:R-OSA-1119344] Hydroxycinnamic acid serotonin amides biosynthesis - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-1120063] serotonin+(E)-cinnamoyl-CoA->H++cinnamoylserotonin+coenzyme A - Oryza sativa [Reaction:R-OSA-1119839] feruloyl-CoA+serotonin->H++feruloylserotonin+coenzyme A - Oryza sativa [Reaction:R-OSA-1120840] 4-coumaroyl-CoA+serotonin->H++p-coumaroylserotonin+coenzyme A - Oryza sativa [Reaction:R-OSA-1119798] serotonin+caffeoyl-CoA->H++caffeoylserotonin+coenzyme A - Oryza sativa