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Aromatic-L-amino-acid decarboxylase

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catalystActivity	[CatalystActivity:1119199] aromatic-L-amino-acid decarboxylase activity of Tryptophan decarboxylase [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:27869] EC:4.1.1.28 [DatabaseIdentifier:1137532] RiceCyc:AROMATIC-L-AMINO-ACID-DECARBOXYLASE-RXN
dbId	1121156
displayName	Aromatic-L-amino-acid decarboxylase
eventOf	[Pathway:R-OSA-1119344] Hydroxycinnamic acid serotonin amides biosynthesis - Oryza sativa [Pathway:R-OSA-1119486] IAA biosynthesis I - Oryza sativa [Pathway:R-OSA-1119438] Secologanin and strictosidine biosynthesis - Oryza sativa
followingEvent	[Reaction:R-OSA-1121110] tryptamine+O2+NADPH->N-hydroxyl-tryptamine+H2O+NADP+ - Oryza sativa [Reaction:R-OSA-1120655] tryptamine+H2O+O2->ammonia+indole acetaldehyde+H2O2 - Oryza sativa [Reaction:R-OSA-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Oryza sativa [Reaction:R-OSA-1120512] Strictosidine synthase - Oryza sativa
input	[SimpleEntity:R-ALL-29500] L-Trp [cytosol]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	Aromatic-L-amino-acid decarboxylase Hydroxytryptophan decarboxylase Tryptophan decarboxylase DOPA decarboxylase biochemicalReaction14794
orthologousEvent	[Reaction:R-OES-1121156] Aromatic-L-amino-acid decarboxylase - Olea europaea var. sylvestris [Reaction:R-HLH-1121156] Aromatic-L-amino-acid decarboxylase - Humulus lupulus [Reaction:R-CRU-1121156] Aromatic-L-amino-acid decarboxylase - Capsella rubella [Reaction:R-PED-1121156] Aromatic-L-amino-acid decarboxylase - Phyllostachys edulis [Reaction:R-CCP-1121156] Aromatic-L-amino-acid decarboxylase - Corchorus capsularis [Reaction:R-SMO-1121156] Aromatic-L-amino-acid decarboxylase - Selaginella moellendorffii [Reaction:R-LPE-1121156] Aromatic-L-amino-acid decarboxylase - Leersia perrieri [Reaction:R-ECU-1121156] Aromatic-L-amino-acid decarboxylase - Eragrostis curvula [Reaction:R-FVE-1121156] Aromatic-L-amino-acid decarboxylase - Fragaria vesca [Reaction:R-GRA-1121156] Aromatic-L-amino-acid decarboxylase - Gossypium raimondii [Reaction:R-CSA-1121156] Aromatic-L-amino-acid decarboxylase - Cucumis sativus [Reaction:R-CAR-1121156] Aromatic-L-amino-acid decarboxylase - Cicer arietinum [Reaction:R-CSI-1121156] Aromatic-L-amino-acid decarboxylase - Citrus sinensis [Reaction:R-TPR-1121156] Aromatic-L-amino-acid decarboxylase - Trifolium pratense [Reaction:R-JRE-1121156] Aromatic-L-amino-acid decarboxylase - Juglans regia [Reaction:R-AIP-1121156] Aromatic-L-amino-acid decarboxylase - Arachis ipaensis [Reaction:R-EGR-1121156] Aromatic-L-amino-acid decarboxylase - Eucalyptus grandis [Reaction:R-PVE-1121156] Aromatic-L-amino-acid decarboxylase - Pistacia vera [Reaction:R-MGU-1121156] Aromatic-L-amino-acid decarboxylase - Erythranthe guttata [Reaction:R-CCN-1121156] Aromatic-L-amino-acid decarboxylase - Coffea canephora [Reaction:R-LAN-1121156] Aromatic-L-amino-acid decarboxylase - Lupinus angustifolius [Reaction:R-SBI-1121156] Aromatic-L-amino-acid decarboxylase - Sorghum bicolor [Reaction:R-NNU-1121156] Aromatic-L-amino-acid decarboxylase - Nelumbo nucifera [Reaction:R-PPA-1121156] Aromatic-L-amino-acid decarboxylase - Physcomitrella patens [Reaction:R-AUM-1121156] Aromatic-L-amino-acid decarboxylase - Aegilops umbellulata [Reaction:R-MDO-1121156] Aromatic-L-amino-acid decarboxylase - Malus domestica [Reaction:R-TSP-1121156] Aromatic-L-amino-acid decarboxylase - Triticum spelta subsp. spelta [Reaction:R-CCA-1121156] Aromatic-L-amino-acid decarboxylase - Cajanus cajan [Reaction:R-CST-1121156] Aromatic-L-amino-acid decarboxylase - Camelina sativa [Reaction:R-ORU-1121156] Aromatic-L-amino-acid decarboxylase - Oryza rufipogon [Reaction:R-OLO-1121156] Aromatic-L-amino-acid decarboxylase - Oryza longistaminata [Reaction:R-SSP-1121156] Aromatic-L-amino-acid decarboxylase - Saccharum spontaneum [Reaction:R-VFA-1121156] Aromatic-L-amino-acid decarboxylase - Vicia faba var. faba [Reaction:R-COL-1121156] Aromatic-L-amino-acid decarboxylase - Corchorus olitorius [Reaction:R-OGR-1121156] Aromatic-L-amino-acid decarboxylase - Oryza meyeriana var. granulata [Reaction:R-LSA-1121156] Aromatic-L-amino-acid decarboxylase - Lactuca sativa [Reaction:R-CCI-1121156] Aromatic-L-amino-acid decarboxylase - Corymbia citriodora [Reaction:R-CLA-1121156] Aromatic-L-amino-acid decarboxylase - Citrullus lanatus [Reaction:R-DCA-1121156] Aromatic-L-amino-acid decarboxylase - Daucus carota [Reaction:R-PHA-1121156] Aromatic-L-amino-acid decarboxylase - Panicum hallii ("FIL2") [Reaction:R-SVI-1121156] Aromatic-L-amino-acid decarboxylase - Setaria viridis [Reaction:R-CQI-1121156] Aromatic-L-amino-acid decarboxylase - Chenopodium quinoa [Reaction:R-ZMA-1121156] Aromatic-L-amino-acid decarboxylase - Zea mays [Reaction:R-NCO-1121156] Aromatic-L-amino-acid decarboxylase - Nymphaea colorata [Reaction:R-CBA-1121156] Aromatic-L-amino-acid decarboxylase - Chara braunii [Reaction:R-VRA-1121156] Aromatic-L-amino-acid decarboxylase - Vigna radiata [Reaction:R-ALY-1121156] Aromatic-L-amino-acid decarboxylase - Arabidopsis lyrata [Reaction:R-OPU-1121156] Aromatic-L-amino-acid decarboxylase - Oryza punctata [Reaction:R-BOL-1121156] Aromatic-L-amino-acid decarboxylase - Brassica oleracea [Reaction:R-VAN-1121156] Aromatic-L-amino-acid decarboxylase - Vigna angularis [Reaction:R-SIN-1121156] Aromatic-L-amino-acid decarboxylase - Sesamum indicum [Reaction:R-HAN-1121156] Aromatic-L-amino-acid decarboxylase - Helianthus annuus [Reaction:R-CAN-1121156] Aromatic-L-amino-acid decarboxylase - Capsicum annuum [Reaction:R-FEX-1121156] Aromatic-L-amino-acid decarboxylase - Fraxinus excelsior (European ash) [Reaction:R-QLO-1121156] Aromatic-L-amino-acid decarboxylase - Quercus lobata [Reaction:R-STU-1121156] Aromatic-L-amino-acid decarboxylase - Solanum tuberosum [Reaction:R-LPR-1121156] Aromatic-L-amino-acid decarboxylase - Lolium perenne [Reaction:R-DRO-1121156] Aromatic-L-amino-acid decarboxylase - Dioscorea rotundata [Reaction:R-ITR-1121156] Aromatic-L-amino-acid decarboxylase - Ipomoea triloba [Reaction:R-TTI-1121156] Aromatic-L-amino-acid decarboxylase - Triticum timopheevii subsp. timopheevii [Reaction:R-OBR-1121156] Aromatic-L-amino-acid decarboxylase - Oryza brachyantha [Reaction:R-OMI-1121156] Aromatic-L-amino-acid decarboxylase - Oryza minuta [Reaction:R-AOF-1121156] Aromatic-L-amino-acid decarboxylase - Asparagus officinalis [Reaction:R-OKA-1121156] Aromatic-L-amino-acid decarboxylase - Oryza sativa aus subgroup [Reaction:R-BDI-1121156] Aromatic-L-amino-acid decarboxylase - Brachypodium distachyon [Reaction:R-PVU-1121156] Aromatic-L-amino-acid decarboxylase - Phaseolus vulgaris [Reaction:R-ATR-1121156] Aromatic-L-amino-acid decarboxylase - Amborella trichopoda [Reaction:R-ADU-1121156] Aromatic-L-amino-acid decarboxylase - Arachis duranensis [Reaction:R-CRE-1121156] Aromatic-L-amino-acid decarboxylase - Chlamydomonas reinhardtii [Reaction:R-PPE-1121156] Aromatic-L-amino-acid decarboxylase - Prunus persica [Reaction:R-PSA-1121156] Aromatic-L-amino-acid decarboxylase - Pisum sativum [Reaction:R-LST-1121156] Aromatic-L-amino-acid decarboxylase - Lathyrus sativus [Reaction:R-SCR-1121156] Aromatic-L-amino-acid decarboxylase - Secale cereale [Reaction:R-PTA-1121156] Aromatic-L-amino-acid decarboxylase - Pinus taeda [Reaction:R-TTU-1121156] Aromatic-L-amino-acid decarboxylase - Triticum turgidum [Reaction:R-OGU-1121156] Aromatic-L-amino-acid decarboxylase - Oryza glumaepatula [Reaction:R-TDI-1121156] Aromatic-L-amino-acid decarboxylase - Triticum dicoccoides [Reaction:R-PHH-1121156] Aromatic-L-amino-acid decarboxylase - Panicum hallii var. hallii ("HAL2") [Reaction:R-ACO-1121156] Aromatic-L-amino-acid decarboxylase - Ananas comosus [Reaction:R-MPO-1121156] Aromatic-L-amino-acid decarboxylase - Marchantia polymorpha [Reaction:R-DEX-1121156] Aromatic-L-amino-acid decarboxylase - Digitaria exilis [Reaction:R-GSO-1121156] Aromatic-L-amino-acid decarboxylase - Glycine soja [Reaction:R-HVU-1121156] Aromatic-L-amino-acid decarboxylase - Hordeum vulgare [Reaction:R-FCR-1121156] Aromatic-L-amino-acid decarboxylase - Ficus carica [Reaction:R-OME-1121156] Aromatic-L-amino-acid decarboxylase - Oryza meridionalis [Reaction:R-BNA-1121156] Aromatic-L-amino-acid decarboxylase - Brassica napus [Reaction:R-OOF-1121156] Aromatic-L-amino-acid decarboxylase - Oryza officinalis [Reaction:R-AHA-1121156] Aromatic-L-amino-acid decarboxylase - Arabidopsis halleri [Reaction:R-CCL-1121156] Aromatic-L-amino-acid decarboxylase - Citrus clementina [Reaction:R-SHI-1121156] Aromatic-L-amino-acid decarboxylase - Salvia hispanica [Reaction:R-TCA-1121156] Aromatic-L-amino-acid decarboxylase - Theobroma cacao [Reaction:R-OSI-1121156] Aromatic-L-amino-acid decarboxylase - Oryza sativa Indica Group [Reaction:R-SLY-1121156] Aromatic-L-amino-acid decarboxylase - Solanum lycopersicum [Reaction:R-ATA-1121156] Aromatic-L-amino-acid decarboxylase - Aegilops tauschii [Reaction:R-ETE-1121156] Aromatic-L-amino-acid decarboxylase - Eragrostis tef [Reaction:R-PTI-1121156] Aromatic-L-amino-acid decarboxylase - Populus trichocarpa [Reaction:R-ZJA-1121156] Aromatic-L-amino-acid decarboxylase - Zoysia japonica [Reaction:R-BJU-1121156] Aromatic-L-amino-acid decarboxylase - Brassica juncea [Reaction:R-VUN-1121156] Aromatic-L-amino-acid decarboxylase - Vigna unguiculata [Reaction:R-OEU-1121156] Aromatic-L-amino-acid decarboxylase - Olea europaea [Reaction:R-ONI-1121156] Aromatic-L-amino-acid decarboxylase - Oryza nivara [Reaction:R-CSK-1121156] Aromatic-L-amino-acid decarboxylase - Cannabis sativa subsp. indica [Reaction:R-TUR-1121156] Aromatic-L-amino-acid decarboxylase - Triticum urartu [Reaction:R-BVU-1121156] Aromatic-L-amino-acid decarboxylase - Beta vulgaris [Reaction:R-RCH-1121156] Aromatic-L-amino-acid decarboxylase - Rosa chinensis [Reaction:R-ECG-1121156] Aromatic-L-amino-acid decarboxylase - Echinochloa crus-galli [Reaction:R-BRA-1121156] Aromatic-L-amino-acid decarboxylase - Brassica rapa [Reaction:R-ZMY-1121156] Aromatic-L-amino-acid decarboxylase - Zea mays ver5 [Reaction:R-JCU-1121156] Aromatic-L-amino-acid decarboxylase - Jatropha curcas [Reaction:R-MAC-1121156] Aromatic-L-amino-acid decarboxylase - Musa acuminata [Reaction:R-PDA-1121156] Aromatic-L-amino-acid decarboxylase - Phoenix dactylifera [Reaction:R-PSO-1121156] Aromatic-L-amino-acid decarboxylase - Papaver somniferum [Reaction:R-GMA-1121156] Aromatic-L-amino-acid decarboxylase - Glycine max [Reaction:R-ACH-1121156] Aromatic-L-amino-acid decarboxylase - Actinidia chinensis [Reaction:R-PAV-1121156] Aromatic-L-amino-acid decarboxylase - Prunus avium [Reaction:R-NAT-1121156] Aromatic-L-amino-acid decarboxylase - Nicotiana attenuata [Reaction:R-MES-1121156] Aromatic-L-amino-acid decarboxylase - Manihot esculenta [Reaction:R-AHY-1121156] Aromatic-L-amino-acid decarboxylase - Arachis hypogaea [Reaction:R-OBA-1121156] Aromatic-L-amino-acid decarboxylase - Oryza barthii [Reaction:R-OGL-1121156] Aromatic-L-amino-acid decarboxylase - Oryza glaberrima [Reaction:R-CSC-1121156] Aromatic-L-amino-acid decarboxylase - Cannabis sativa [Reaction:R-CML-1121156] Aromatic-L-amino-acid decarboxylase - Cucumis melo [Reaction:R-QSU-1121156] Aromatic-L-amino-acid decarboxylase - Quercus suber [Reaction:R-MTR-1121156] Aromatic-L-amino-acid decarboxylase - Medicago truncatula [Reaction:R-OAU-1121156] Aromatic-L-amino-acid decarboxylase - Oryza australiensis [Reaction:R-TAE-1121156] Aromatic-L-amino-acid decarboxylase - Triticum aestivum [Reaction:R-HLP-1121156] Aromatic-L-amino-acid decarboxylase - Humulus lupulus var. lupulus [Reaction:R-ATH-1121156] Aromatic-L-amino-acid decarboxylase - Arabidopsis thaliana [Reaction:R-CCD-1121156] Aromatic-L-amino-acid decarboxylase - Cynara cardunculus var. scolymus [Reaction:R-VVN-1121156] Aromatic-L-amino-acid decarboxylase - Vitis vinifera [Reaction:R-ASA-1121156] Aromatic-L-amino-acid decarboxylase - Avena sativa [Reaction:R-SIT-1121156] Aromatic-L-amino-acid decarboxylase - Setaria italica
output	[SimpleEntity:R-ALL-113528] CO2 [cytosol] [SimpleEntity:R-ALL-1132116] tryptamine [cytosol]
reviewed	[InstanceEdit:2879026] Dharmawardhana, DP, 2012-12-19 [InstanceEdit:2744296] Amarasinghe, V, 2012-11-29
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1121156
summation	[Summation:2879032] L-tryptophan is converted into tryptamine by enzymatic activ...

Referrals

(hasEvent)	[Pathway:R-OSA-1119486] IAA biosynthesis I - Oryza sativa [Pathway:R-OSA-1119344] Hydroxycinnamic acid serotonin amides biosynthesis - Oryza sativa [Pathway:R-OSA-1119438] Secologanin and strictosidine biosynthesis - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-1120655] tryptamine+H2O+O2->ammonia+indole acetaldehyde+H2O2 - Oryza sativa [Reaction:R-OSA-1121110] tryptamine+O2+NADPH->N-hydroxyl-tryptamine+H2O+NADP+ - Oryza sativa [Reaction:R-OSA-1121159] tryptamine+NAD(P)H+H++O2->serotonin+NAD(P)++H2 - Oryza sativa [Reaction:R-OSA-1120512] Strictosidine synthase - Oryza sativa