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dihydrodipicolinate reductase

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catalystActivity	[CatalystActivity:1118859] 4-hydroxy-tetrahydrodipicolinate reductase activity of dihydrodipicolinate reductase [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:26791] EC:1.3.1.26 [DatabaseIdentifier:1152938] RiceCyc:DIHYDROPICRED-RXN
dbId	1120601
displayName	dihydrodipicolinate reductase
eventOf	[Pathway:R-OSA-1119273] Lysine biosynthesis I - Oryza sativa [Pathway:R-OSA-1119283] Lysine biosynthesis II - Oryza sativa
followingEvent	[Reaction:R-OSA-1120089] tetrahydrodipicolinate N-acetyltransferase - Oryza sativa [Reaction:R-OSA-1120409] 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase - Oryza sativa [Reaction:R-OSA-5606520] diaminopimelate aminotransferase plastidic - Oryza sativa
input	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-1131090] L-2,3-dihydrodipicolinate [cytosol] [DefinedSet:R-ALL-428206] NAD(P)H [cytosol]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	dihydrodipicolinate reductase biochemicalReaction81210
orthologousEvent	[Reaction:R-LAN-1120601] dihydrodipicolinate reductase - Lupinus angustifolius [Reaction:R-HVU-1120601] dihydrodipicolinate reductase - Hordeum vulgare [Reaction:R-CSI-1120601] dihydrodipicolinate reductase - Citrus sinensis [Reaction:R-PDA-1120601] dihydrodipicolinate reductase - Phoenix dactylifera [Reaction:R-EGR-1120601] dihydrodipicolinate reductase - Eucalyptus grandis [Reaction:R-SIT-1120601] dihydrodipicolinate reductase - Setaria italica [Reaction:R-MPO-1120601] dihydrodipicolinate reductase - Marchantia polymorpha [Reaction:R-OGR-1120601] dihydrodipicolinate reductase - Oryza meyeriana var. granulata [Reaction:R-CME-1120601] dihydrodipicolinate reductase - Cyanidioschyzon merolae [Reaction:R-TCA-1120601] dihydrodipicolinate reductase - Theobroma cacao [Reaction:R-FEX-1120601] dihydrodipicolinate reductase - Fraxinus excelsior (European ash) [Reaction:R-TDI-1120601] dihydrodipicolinate reductase - Triticum dicoccoides [Reaction:R-ZJA-1120601] dihydrodipicolinate reductase - Zoysia japonica [Reaction:R-SMO-1120601] dihydrodipicolinate reductase - Selaginella moellendorffii [Reaction:R-ECU-1120601] dihydrodipicolinate reductase - Eragrostis curvula [Reaction:R-ACH-1120601] dihydrodipicolinate reductase - Actinidia chinensis [Reaction:R-CST-1120601] dihydrodipicolinate reductase - Camelina sativa [Reaction:R-CLA-1120601] dihydrodipicolinate reductase - Citrullus lanatus [Reaction:R-OKA-1120601] dihydrodipicolinate reductase - Oryza sativa aus subgroup [Reaction:R-OAU-1120601] dihydrodipicolinate reductase - Oryza australiensis [Reaction:R-CCL-1120601] dihydrodipicolinate reductase - Citrus clementina [Reaction:R-AIP-1120601] dihydrodipicolinate reductase - Arachis ipaensis [Reaction:R-ZMA-1120601] dihydrodipicolinate reductase - Zea mays [Reaction:R-PTI-1120601] dihydrodipicolinate reductase - Populus trichocarpa [Reaction:R-SCR-1120601] dihydrodipicolinate reductase - Secale cereale [Reaction:R-STU-1120601] dihydrodipicolinate reductase - Solanum tuberosum [Reaction:R-LST-1120601] dihydrodipicolinate reductase - Lathyrus sativus [Reaction:R-FCR-1120601] dihydrodipicolinate reductase - Ficus carica [Reaction:R-SHI-1120601] dihydrodipicolinate reductase - Salvia hispanica [Reaction:R-PPE-1120601] dihydrodipicolinate reductase - Prunus persica [Reaction:R-OBA-1120601] dihydrodipicolinate reductase - Oryza barthii [Reaction:R-CAR-1120601] dihydrodipicolinate reductase - Cicer arietinum [Reaction:R-OGU-1120601] dihydrodipicolinate reductase - Oryza glumaepatula [Reaction:R-OOF-1120601] dihydrodipicolinate reductase - Oryza officinalis [Reaction:R-PVU-1120601] dihydrodipicolinate reductase - Phaseolus vulgaris [Reaction:R-OLU-1120601] dihydrodipicolinate reductase - Ostreococcus lucimarinus [Reaction:R-FVE-1120601] dihydrodipicolinate reductase - Fragaria vesca [Reaction:R-MDO-1120601] dihydrodipicolinate reductase - Malus domestica [Reaction:R-PSO-1120601] dihydrodipicolinate reductase - Papaver somniferum [Reaction:R-LSA-1120601] dihydrodipicolinate reductase - Lactuca sativa [Reaction:R-QSU-1120601] dihydrodipicolinate reductase - Quercus suber [Reaction:R-OLO-1120601] dihydrodipicolinate reductase - Oryza longistaminata [Reaction:R-SVI-1120601] dihydrodipicolinate reductase - Setaria viridis [Reaction:R-ACO-1120601] dihydrodipicolinate reductase - Ananas comosus [Reaction:R-CRU-1120601] dihydrodipicolinate reductase - Capsella rubella [Reaction:R-TAE-1120601] dihydrodipicolinate reductase - Triticum aestivum [Reaction:R-PPA-1120601] dihydrodipicolinate reductase - Physcomitrella patens [Reaction:R-CRE-1120601] dihydrodipicolinate reductase - Chlamydomonas reinhardtii [Reaction:R-CCA-1120601] dihydrodipicolinate reductase - Cajanus cajan [Reaction:R-MTR-1120601] dihydrodipicolinate reductase - Medicago truncatula [Reaction:R-VFA-1120601] dihydrodipicolinate reductase - Vicia faba var. faba [Reaction:R-SIN-1120601] dihydrodipicolinate reductase - Sesamum indicum [Reaction:R-NAT-1120601] dihydrodipicolinate reductase - Nicotiana attenuata [Reaction:R-ITR-1120601] dihydrodipicolinate reductase - Ipomoea triloba [Reaction:R-CSC-1120601] dihydrodipicolinate reductase - Cannabis sativa [Reaction:R-OPU-1120601] dihydrodipicolinate reductase - Oryza punctata [Reaction:R-CBA-1120601] dihydrodipicolinate reductase - Chara braunii [Reaction:R-PHH-1120601] dihydrodipicolinate reductase - Panicum hallii var. hallii ("HAL2") [Reaction:R-LPR-1120601] dihydrodipicolinate reductase - Lolium perenne [Reaction:R-HLP-1120601] dihydrodipicolinate reductase - Humulus lupulus var. lupulus [Reaction:R-PED-1120601] dihydrodipicolinate reductase - Phyllostachys edulis [Reaction:R-AHY-1120601] dihydrodipicolinate reductase - Arachis hypogaea [Reaction:R-ETE-1120601] dihydrodipicolinate reductase - Eragrostis tef [Reaction:R-ONI-1120601] dihydrodipicolinate reductase - Oryza nivara [Reaction:R-MAC-1120601] dihydrodipicolinate reductase - Musa acuminata [Reaction:R-COL-1120601] dihydrodipicolinate reductase - Corchorus olitorius [Reaction:R-GSO-1120601] dihydrodipicolinate reductase - Glycine soja [Reaction:R-CCP-1120601] dihydrodipicolinate reductase - Corchorus capsularis [Reaction:R-PTA-1120601] dihydrodipicolinate reductase - Pinus taeda [Reaction:R-DRO-1120601] dihydrodipicolinate reductase - Dioscorea rotundata [Reaction:R-AOF-1120601] dihydrodipicolinate reductase - Asparagus officinalis [Reaction:R-OEU-1120601] dihydrodipicolinate reductase - Olea europaea [Reaction:R-ADU-1120601] dihydrodipicolinate reductase - Arachis duranensis [Reaction:R-PSA-1120601] dihydrodipicolinate reductase - Pisum sativum [Reaction:R-ALY-1120601] dihydrodipicolinate reductase - Arabidopsis lyrata [Reaction:R-OMI-1120601] dihydrodipicolinate reductase - Oryza minuta [Reaction:R-CQI-1120601] dihydrodipicolinate reductase - Chenopodium quinoa [Reaction:R-SPC-1120601] dihydrodipicolinate reductase - Synechocystis sp. PCC 6803 [Reaction:R-QLO-1120601] dihydrodipicolinate reductase - Quercus lobata [Reaction:R-ATR-1120601] dihydrodipicolinate reductase - Amborella trichopoda [Reaction:R-TTU-1120601] dihydrodipicolinate reductase - Triticum turgidum [Reaction:R-CSA-1120601] dihydrodipicolinate reductase - Cucumis sativus [Reaction:R-CAN-1120601] dihydrodipicolinate reductase - Capsicum annuum [Reaction:R-BJU-1120601] dihydrodipicolinate reductase - Brassica juncea [Reaction:R-VUN-1120601] dihydrodipicolinate reductase - Vigna unguiculata [Reaction:R-ORU-1120601] dihydrodipicolinate reductase - Oryza rufipogon [Reaction:R-NNU-1120601] dihydrodipicolinate reductase - Nelumbo nucifera [Reaction:R-PHA-1120601] dihydrodipicolinate reductase - Panicum hallii ("FIL2") [Reaction:R-DCA-1120601] dihydrodipicolinate reductase - Daucus carota [Reaction:R-VRA-1120601] dihydrodipicolinate reductase - Vigna radiata [Reaction:R-GSU-1120601] dihydrodipicolinate reductase - Galdieria sulphuraria [Reaction:R-BVU-1120601] dihydrodipicolinate reductase - Beta vulgaris [Reaction:R-OSI-1120601] dihydrodipicolinate reductase - Oryza sativa Indica Group [Reaction:R-GMA-1120601] dihydrodipicolinate reductase - Glycine max [Reaction:R-CCI-1120601] dihydrodipicolinate reductase - Corymbia citriodora [Reaction:R-SSP-1120601] dihydrodipicolinate reductase - Saccharum spontaneum [Reaction:R-ECG-1120601] dihydrodipicolinate reductase - Echinochloa crus-galli [Reaction:R-CCD-1120601] dihydrodipicolinate reductase - Cynara cardunculus var. scolymus [Reaction:R-AUM-1120601] dihydrodipicolinate reductase - Aegilops umbellulata [Reaction:R-OGL-1120601] dihydrodipicolinate reductase - Oryza glaberrima [Reaction:R-SLY-1120601] dihydrodipicolinate reductase - Solanum lycopersicum [Reaction:R-AHA-1120601] dihydrodipicolinate reductase - Arabidopsis halleri [Reaction:R-JCU-1120601] dihydrodipicolinate reductase - Jatropha curcas [Reaction:R-NCO-1120601] dihydrodipicolinate reductase - Nymphaea colorata [Reaction:R-TPR-1120601] dihydrodipicolinate reductase - Trifolium pratense [Reaction:R-BNA-1120601] dihydrodipicolinate reductase - Brassica napus [Reaction:R-GRA-1120601] dihydrodipicolinate reductase - Gossypium raimondii [Reaction:R-OES-1120601] dihydrodipicolinate reductase - Olea europaea var. sylvestris [Reaction:R-VVN-1120601] dihydrodipicolinate reductase - Vitis vinifera [Reaction:R-PVE-1120601] dihydrodipicolinate reductase - Pistacia vera [Reaction:R-HAN-1120601] dihydrodipicolinate reductase - Helianthus annuus [Reaction:R-BOL-1120601] dihydrodipicolinate reductase - Brassica oleracea [Reaction:R-OME-1120601] dihydrodipicolinate reductase - Oryza meridionalis [Reaction:R-PAV-1120601] dihydrodipicolinate reductase - Prunus avium [Reaction:R-ATH-1120601] dihydrodipicolinate reductase - Arabidopsis thaliana [Reaction:R-BDI-1120601] dihydrodipicolinate reductase - Brachypodium distachyon [Reaction:R-TSP-1120601] dihydrodipicolinate reductase - Triticum spelta subsp. spelta [Reaction:R-VAN-1120601] dihydrodipicolinate reductase - Vigna angularis [Reaction:R-SBI-1120601] dihydrodipicolinate reductase - Sorghum bicolor [Reaction:R-MGU-1120601] dihydrodipicolinate reductase - Erythranthe guttata [Reaction:R-HLH-1120601] dihydrodipicolinate reductase - Humulus lupulus [Reaction:R-JRE-1120601] dihydrodipicolinate reductase - Juglans regia [Reaction:R-RCH-1120601] dihydrodipicolinate reductase - Rosa chinensis [Reaction:R-MES-1120601] dihydrodipicolinate reductase - Manihot esculenta [Reaction:R-CCR-1120601] dihydrodipicolinate reductase - Chondrus crispus [Reaction:R-TUR-1120601] dihydrodipicolinate reductase - Triticum urartu [Reaction:R-ATA-1120601] dihydrodipicolinate reductase - Aegilops tauschii [Reaction:R-CCN-1120601] dihydrodipicolinate reductase - Coffea canephora [Reaction:R-ZMY-1120601] dihydrodipicolinate reductase - Zea mays ver5 [Reaction:R-ASA-1120601] dihydrodipicolinate reductase - Avena sativa [Reaction:R-TTI-1120601] dihydrodipicolinate reductase - Triticum timopheevii subsp. timopheevii [Reaction:R-LPE-1120601] dihydrodipicolinate reductase - Leersia perrieri [Reaction:R-DEX-1120601] dihydrodipicolinate reductase - Digitaria exilis [Reaction:R-OBR-1120601] dihydrodipicolinate reductase - Oryza brachyantha [Reaction:R-CSK-1120601] dihydrodipicolinate reductase - Cannabis sativa subsp. indica [Reaction:R-CML-1120601] dihydrodipicolinate reductase - Cucumis melo [Reaction:R-BRA-1120601] dihydrodipicolinate reductase - Brassica rapa [Reaction:R-PAB-1120601] dihydrodipicolinate reductase - Picea abies
output	[DefinedSet:R-ALL-428218] NAD(P)+ [cytosol] [SimpleEntity:R-ALL-1131714] tetrahydrodipicolinate [cytosol]
precedingEvent	[Reaction:R-OSA-1121629] dihydrodipicolinate synthase - Oryza sativa
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1120601
summation	[Summation:2879982] L-2,3-dihydrodipicolinate is converted to tetrahydrodipicoli...

Referrals

(hasEvent)	[Pathway:R-OSA-1119273] Lysine biosynthesis I - Oryza sativa [Pathway:R-OSA-1119283] Lysine biosynthesis II - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-5606520] diaminopimelate aminotransferase plastidic - Oryza sativa [Reaction:R-OSA-1120089] tetrahydrodipicolinate N-acetyltransferase - Oryza sativa [Reaction:R-OSA-1120409] 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase - Oryza sativa