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Acetyl-CoA C-acetyltransferase

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catalystActivity	[CatalystActivity:1118414] acetyl-CoA C-acetyltransferase activity of acetyl-CoA C-acetyltransferase [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:27049] EC:2.3.1.9 [DatabaseIdentifier:1139235] RiceCyc:ACETYL-COA-ACETYLTRANSFER-RXN
dbId	1120481
displayName	Acetyl-CoA C-acetyltransferase
eventOf	[Pathway:R-OSA-1119615] Mevalonate pathway - Oryza sativa
followingEvent	[Reaction:R-OSA-1120444] Hydroxymethylglutaryl-CoA synthase - Oryza sativa
input	2 × [SimpleEntity:R-ALL-76183] Ac-CoA [cytosol]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	Acetyl-CoA C-acetyltransferase ACETYL-COENZYME A ACETYLTRANSFERASE 2 Acetoacetyl-CoA thiolase biochemicalReaction75682
orthologousEvent	[Reaction:R-AHY-1120481] Acetyl-CoA C-acetyltransferase - Arachis hypogaea [Reaction:R-GMA-1120481] Acetyl-CoA C-acetyltransferase - Glycine max [Reaction:R-CAR-1120481] Acetyl-CoA C-acetyltransferase - Cicer arietinum [Reaction:R-DEX-1120481] Acetyl-CoA C-acetyltransferase - Digitaria exilis [Reaction:R-PTA-1120481] Acetyl-CoA C-acetyltransferase - Pinus taeda [Reaction:R-PED-1120481] Acetyl-CoA C-acetyltransferase - Phyllostachys edulis [Reaction:R-ZJA-1120481] Acetyl-CoA C-acetyltransferase - Zoysia japonica [Reaction:R-CAN-1120481] Acetyl-CoA C-acetyltransferase - Capsicum annuum [Reaction:R-NNU-1120481] Acetyl-CoA C-acetyltransferase - Nelumbo nucifera [Reaction:R-CBA-1120481] Acetyl-CoA C-acetyltransferase - Chara braunii [Reaction:R-JCU-1120481] Acetyl-CoA C-acetyltransferase - Jatropha curcas [Reaction:R-ASA-1120481] Acetyl-CoA C-acetyltransferase - Avena sativa [Reaction:R-HAN-1120481] Acetyl-CoA C-acetyltransferase - Helianthus annuus [Reaction:R-CCA-1120481] Acetyl-CoA C-acetyltransferase - Cajanus cajan [Reaction:R-TDI-1120481] Acetyl-CoA C-acetyltransferase - Triticum dicoccoides [Reaction:R-ADU-1120481] Acetyl-CoA C-acetyltransferase - Arachis duranensis [Reaction:R-QLO-1120481] Acetyl-CoA C-acetyltransferase - Quercus lobata [Reaction:R-ALY-1120481] Acetyl-CoA C-acetyltransferase - Arabidopsis lyrata [Reaction:R-PTI-1120481] Acetyl-CoA C-acetyltransferase - Populus trichocarpa [Reaction:R-DCA-1120481] Acetyl-CoA C-acetyltransferase - Daucus carota [Reaction:R-ATH-1120481] Acetyl-CoA C-acetyltransferase - Arabidopsis thaliana [Reaction:R-PDA-1120481] Acetyl-CoA C-acetyltransferase - Phoenix dactylifera [Reaction:R-CRE-1120481] Acetyl-CoA C-acetyltransferase - Chlamydomonas reinhardtii [Reaction:R-PHH-1120481] Acetyl-CoA C-acetyltransferase - Panicum hallii var. hallii ("HAL2") [Reaction:R-QSU-1120481] Acetyl-CoA C-acetyltransferase - Quercus suber [Reaction:R-CCI-1120481] Acetyl-CoA C-acetyltransferase - Corymbia citriodora [Reaction:R-TUR-1120481] Acetyl-CoA C-acetyltransferase - Triticum urartu [Reaction:R-AIP-1120481] Acetyl-CoA C-acetyltransferase - Arachis ipaensis [Reaction:R-PVE-1120481] Acetyl-CoA C-acetyltransferase - Pistacia vera [Reaction:R-AUM-1120481] Acetyl-CoA C-acetyltransferase - Aegilops umbellulata [Reaction:R-VRA-1120481] Acetyl-CoA C-acetyltransferase - Vigna radiata [Reaction:R-OME-1120481] Acetyl-CoA C-acetyltransferase - Oryza meridionalis [Reaction:R-HLH-1120481] Acetyl-CoA C-acetyltransferase - Humulus lupulus [Reaction:R-SPC-1120481] Acetyl-CoA C-acetyltransferase - Synechocystis sp. PCC 6803 [Reaction:R-FEX-1120481] Acetyl-CoA C-acetyltransferase - Fraxinus excelsior (European ash) [Reaction:R-SIN-1120481] Acetyl-CoA C-acetyltransferase - Sesamum indicum [Reaction:R-ECU-1120481] Acetyl-CoA C-acetyltransferase - Eragrostis curvula [Reaction:R-CCL-1120481] Acetyl-CoA C-acetyltransferase - Citrus clementina [Reaction:R-CCN-1120481] Acetyl-CoA C-acetyltransferase - Coffea canephora [Reaction:R-CCD-1120481] Acetyl-CoA C-acetyltransferase - Cynara cardunculus var. scolymus [Reaction:R-TTI-1120481] Acetyl-CoA C-acetyltransferase - Triticum timopheevii subsp. timopheevii [Reaction:R-LPR-1120481] Acetyl-CoA C-acetyltransferase - Lolium perenne [Reaction:R-VUN-1120481] Acetyl-CoA C-acetyltransferase - Vigna unguiculata [Reaction:R-CSC-1120481] Acetyl-CoA C-acetyltransferase - Cannabis sativa [Reaction:R-OGU-1120481] Acetyl-CoA C-acetyltransferase - Oryza glumaepatula [Reaction:R-SHI-1120481] Acetyl-CoA C-acetyltransferase - Salvia hispanica [Reaction:R-LST-1120481] Acetyl-CoA C-acetyltransferase - Lathyrus sativus [Reaction:R-PAV-1120481] Acetyl-CoA C-acetyltransferase - Prunus avium [Reaction:R-CST-1120481] Acetyl-CoA C-acetyltransferase - Camelina sativa [Reaction:R-CSK-1120481] Acetyl-CoA C-acetyltransferase - Cannabis sativa subsp. indica [Reaction:R-VAN-1120481] Acetyl-CoA C-acetyltransferase - Vigna angularis [Reaction:R-OGR-1120481] Acetyl-CoA C-acetyltransferase - Oryza meyeriana var. granulata [Reaction:R-OSI-1120481] Acetyl-CoA C-acetyltransferase - Oryza sativa Indica Group [Reaction:R-MTR-1120481] Acetyl-CoA C-acetyltransferase - Medicago truncatula [Reaction:R-AOF-1120481] Acetyl-CoA C-acetyltransferase - Asparagus officinalis [Reaction:R-BJU-1120481] Acetyl-CoA C-acetyltransferase - Brassica juncea [Reaction:R-LSA-1120481] Acetyl-CoA C-acetyltransferase - Lactuca sativa [Reaction:R-SIT-1120481] Acetyl-CoA C-acetyltransferase - Setaria italica [Reaction:R-OKA-1120481] Acetyl-CoA C-acetyltransferase - Oryza sativa aus subgroup [Reaction:R-PPA-1120481] Acetyl-CoA C-acetyltransferase - Physcomitrella patens [Reaction:R-ACH-1120481] Acetyl-CoA C-acetyltransferase - Actinidia chinensis [Reaction:R-ETE-1120481] Acetyl-CoA C-acetyltransferase - Eragrostis tef [Reaction:R-JRE-1120481] Acetyl-CoA C-acetyltransferase - Juglans regia [Reaction:R-ATR-1120481] Acetyl-CoA C-acetyltransferase - Amborella trichopoda [Reaction:R-OES-1120481] Acetyl-CoA C-acetyltransferase - Olea europaea var. sylvestris [Reaction:R-TAE-1120481] Acetyl-CoA C-acetyltransferase - Triticum aestivum [Reaction:R-SCR-1120481] Acetyl-CoA C-acetyltransferase - Secale cereale [Reaction:R-SSP-1120481] Acetyl-CoA C-acetyltransferase - Saccharum spontaneum [Reaction:R-PSO-1120481] Acetyl-CoA C-acetyltransferase - Papaver somniferum [Reaction:R-FVE-1120481] Acetyl-CoA C-acetyltransferase - Fragaria vesca [Reaction:R-TPR-1120481] Acetyl-CoA C-acetyltransferase - Trifolium pratense [Reaction:R-VVN-1120481] Acetyl-CoA C-acetyltransferase - Vitis vinifera [Reaction:R-MES-1120481] Acetyl-CoA C-acetyltransferase - Manihot esculenta [Reaction:R-SVI-1120481] Acetyl-CoA C-acetyltransferase - Setaria viridis [Reaction:R-CML-1120481] Acetyl-CoA C-acetyltransferase - Cucumis melo [Reaction:R-MDO-1120481] Acetyl-CoA C-acetyltransferase - Malus domestica [Reaction:R-RCH-1120481] Acetyl-CoA C-acetyltransferase - Rosa chinensis [Reaction:R-BOL-1120481] Acetyl-CoA C-acetyltransferase - Brassica oleracea [Reaction:R-TTU-1120481] Acetyl-CoA C-acetyltransferase - Triticum turgidum [Reaction:R-ITR-1120481] Acetyl-CoA C-acetyltransferase - Ipomoea triloba [Reaction:R-PSA-1120481] Acetyl-CoA C-acetyltransferase - Pisum sativum [Reaction:R-GSO-1120481] Acetyl-CoA C-acetyltransferase - Glycine soja [Reaction:R-BVU-1120481] Acetyl-CoA C-acetyltransferase - Beta vulgaris [Reaction:R-CSI-1120481] Acetyl-CoA C-acetyltransferase - Citrus sinensis [Reaction:R-ACO-1120481] Acetyl-CoA C-acetyltransferase - Ananas comosus [Reaction:R-TSP-1120481] Acetyl-CoA C-acetyltransferase - Triticum spelta subsp. spelta [Reaction:R-AHA-1120481] Acetyl-CoA C-acetyltransferase - Arabidopsis halleri [Reaction:R-ONI-1120481] Acetyl-CoA C-acetyltransferase - Oryza nivara [Reaction:R-DRO-1120481] Acetyl-CoA C-acetyltransferase - Dioscorea rotundata [Reaction:R-OEU-1120481] Acetyl-CoA C-acetyltransferase - Olea europaea [Reaction:R-ZMA-1120481] Acetyl-CoA C-acetyltransferase - Zea mays [Reaction:R-OMI-1120481] Acetyl-CoA C-acetyltransferase - Oryza minuta [Reaction:R-PVU-1120481] Acetyl-CoA C-acetyltransferase - Phaseolus vulgaris [Reaction:R-BRA-1120481] Acetyl-CoA C-acetyltransferase - Brassica rapa [Reaction:R-BDI-1120481] Acetyl-CoA C-acetyltransferase - Brachypodium distachyon [Reaction:R-CRU-1120481] Acetyl-CoA C-acetyltransferase - Capsella rubella [Reaction:R-MAC-1120481] Acetyl-CoA C-acetyltransferase - Musa acuminata [Reaction:R-MPO-1120481] Acetyl-CoA C-acetyltransferase - Marchantia polymorpha [Reaction:R-EGR-1120481] Acetyl-CoA C-acetyltransferase - Eucalyptus grandis [Reaction:R-OPU-1120481] Acetyl-CoA C-acetyltransferase - Oryza punctata [Reaction:R-ECG-1120481] Acetyl-CoA C-acetyltransferase - Echinochloa crus-galli [Reaction:R-PHA-1120481] Acetyl-CoA C-acetyltransferase - Panicum hallii ("FIL2") [Reaction:R-FCR-1120481] Acetyl-CoA C-acetyltransferase - Ficus carica [Reaction:R-MGU-1120481] Acetyl-CoA C-acetyltransferase - Erythranthe guttata [Reaction:R-STU-1120481] Acetyl-CoA C-acetyltransferase - Solanum tuberosum [Reaction:R-OBR-1120481] Acetyl-CoA C-acetyltransferase - Oryza brachyantha [Reaction:R-CME-1120481] Acetyl-CoA C-acetyltransferase - Cyanidioschyzon merolae [Reaction:R-PPE-1120481] Acetyl-CoA C-acetyltransferase - Prunus persica [Reaction:R-SMO-1120481] Acetyl-CoA C-acetyltransferase - Selaginella moellendorffii [Reaction:R-GRA-1120481] Acetyl-CoA C-acetyltransferase - Gossypium raimondii [Reaction:R-CSA-1120481] Acetyl-CoA C-acetyltransferase - Cucumis sativus [Reaction:R-VFA-1120481] Acetyl-CoA C-acetyltransferase - Vicia faba var. faba [Reaction:R-PAB-1120481] Acetyl-CoA C-acetyltransferase - Picea abies [Reaction:R-OLO-1120481] Acetyl-CoA C-acetyltransferase - Oryza longistaminata [Reaction:R-LAN-1120481] Acetyl-CoA C-acetyltransferase - Lupinus angustifolius [Reaction:R-NCO-1120481] Acetyl-CoA C-acetyltransferase - Nymphaea colorata [Reaction:R-OAU-1120481] Acetyl-CoA C-acetyltransferase - Oryza australiensis [Reaction:R-HLP-1120481] Acetyl-CoA C-acetyltransferase - Humulus lupulus var. lupulus [Reaction:R-TCA-1120481] Acetyl-CoA C-acetyltransferase - Theobroma cacao [Reaction:R-CLA-1120481] Acetyl-CoA C-acetyltransferase - Citrullus lanatus [Reaction:R-ZMY-1120481] Acetyl-CoA C-acetyltransferase - Zea mays ver5 [Reaction:R-OOF-1120481] Acetyl-CoA C-acetyltransferase - Oryza officinalis [Reaction:R-SLY-1120481] Acetyl-CoA C-acetyltransferase - Solanum lycopersicum [Reaction:R-LPE-1120481] Acetyl-CoA C-acetyltransferase - Leersia perrieri [Reaction:R-NAT-1120481] Acetyl-CoA C-acetyltransferase - Nicotiana attenuata [Reaction:R-GSU-1120481] Acetyl-CoA C-acetyltransferase - Galdieria sulphuraria [Reaction:R-COL-1120481] Acetyl-CoA C-acetyltransferase - Corchorus olitorius [Reaction:R-CCP-1120481] Acetyl-CoA C-acetyltransferase - Corchorus capsularis [Reaction:R-OBA-1120481] Acetyl-CoA C-acetyltransferase - Oryza barthii [Reaction:R-BNA-1120481] Acetyl-CoA C-acetyltransferase - Brassica napus [Reaction:R-ATA-1120481] Acetyl-CoA C-acetyltransferase - Aegilops tauschii [Reaction:R-SBI-1120481] Acetyl-CoA C-acetyltransferase - Sorghum bicolor [Reaction:R-CQI-1120481] Acetyl-CoA C-acetyltransferase - Chenopodium quinoa [Reaction:R-ORU-1120481] Acetyl-CoA C-acetyltransferase - Oryza rufipogon [Reaction:R-HVU-1120481] Acetyl-CoA C-acetyltransferase - Hordeum vulgare [Reaction:R-OGL-1120481] Acetyl-CoA C-acetyltransferase - Oryza glaberrima
output	[SimpleEntity:R-ALL-191293] ACA-CoA [cytosol] [SimpleEntity:R-ALL-76194] CoA-SH [cytosol]
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1120481
summation	[Summation:4790371] Acetyl-CoA is converted to acetoacetyl-CoA by enzymatic acti...

Referrals

(hasEvent)	[Pathway:R-OSA-1119615] Mevalonate pathway - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-1120444] Hydroxymethylglutaryl-CoA synthase - Oryza sativa

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