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mevalonate kinase

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catalystActivity	[CatalystActivity:1118198] mevalonate kinase activity of phosphomevalonate kinase (LOC_OS10G18220.1) [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:27243] EC:2.7.1.36 [DatabaseIdentifier:1139625] RiceCyc:MEVALONATE-KINASE-RXN
dbId	1119762
displayName	mevalonate kinase
eventOf	[Pathway:R-OSA-1119615] Mevalonate pathway - Oryza sativa
followingEvent	[Reaction:R-OSA-1119737] phosphomevalonate kinase - Oryza sativa
input	[SimpleEntity:R-ALL-4789847] (R)-mevalonate [cytosol] [SimpleEntity:R-ALL-113592] ATP [cytosol]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	mevalonate kinase biochemicalReaction59069
orthologousEvent	[Reaction:R-PVE-1119762] mevalonate kinase - Pistacia vera [Reaction:R-BRA-1119762] mevalonate kinase - Brassica rapa [Reaction:R-OME-1119762] mevalonate kinase - Oryza meridionalis [Reaction:R-PED-1119762] mevalonate kinase - Phyllostachys edulis [Reaction:R-FEX-1119762] mevalonate kinase - Fraxinus excelsior (European ash) [Reaction:R-VRA-1119762] mevalonate kinase - Vigna radiata [Reaction:R-DRO-1119762] mevalonate kinase - Dioscorea rotundata [Reaction:R-DEX-1119762] mevalonate kinase - Digitaria exilis [Reaction:R-MDO-1119762] mevalonate kinase - Malus domestica [Reaction:R-CAN-1119762] mevalonate kinase - Capsicum annuum [Reaction:R-FCR-1119762] mevalonate kinase - Ficus carica [Reaction:R-PPA-1119762] mevalonate kinase - Physcomitrella patens [Reaction:R-SLY-1119762] mevalonate kinase - Solanum lycopersicum [Reaction:R-OGU-1119762] mevalonate kinase - Oryza glumaepatula [Reaction:R-ACH-1119762] mevalonate kinase - Actinidia chinensis [Reaction:R-OLO-1119762] mevalonate kinase - Oryza longistaminata [Reaction:R-CSK-1119762] mevalonate kinase - Cannabis sativa subsp. indica [Reaction:R-OMI-1119762] mevalonate kinase - Oryza minuta [Reaction:R-TTU-1119762] mevalonate kinase - Triticum turgidum [Reaction:R-PSO-1119762] mevalonate kinase - Papaver somniferum [Reaction:R-GMA-1119762] mevalonate kinase - Glycine max [Reaction:R-ORU-1119762] mevalonate kinase - Oryza rufipogon [Reaction:R-GSO-1119762] mevalonate kinase - Glycine soja [Reaction:R-CCL-1119762] mevalonate kinase - Citrus clementina [Reaction:R-TDI-1119762] mevalonate kinase - Triticum dicoccoides [Reaction:R-PTA-1119762] mevalonate kinase - Pinus taeda [Reaction:R-OBA-1119762] mevalonate kinase - Oryza barthii [Reaction:R-HAN-1119762] mevalonate kinase - Helianthus annuus [Reaction:R-CML-1119762] mevalonate kinase - Cucumis melo [Reaction:R-TTI-1119762] mevalonate kinase - Triticum timopheevii subsp. timopheevii [Reaction:R-TCA-1119762] mevalonate kinase - Theobroma cacao [Reaction:R-CST-1119762] mevalonate kinase - Camelina sativa [Reaction:R-VUN-1119762] mevalonate kinase - Vigna unguiculata [Reaction:R-CAR-1119762] mevalonate kinase - Cicer arietinum [Reaction:R-STU-1119762] mevalonate kinase - Solanum tuberosum [Reaction:R-DCA-1119762] mevalonate kinase - Daucus carota [Reaction:R-LSA-1119762] mevalonate kinase - Lactuca sativa [Reaction:R-ECG-1119762] mevalonate kinase - Echinochloa crus-galli [Reaction:R-AHA-1119762] mevalonate kinase - Arabidopsis halleri [Reaction:R-MPO-1119762] mevalonate kinase - Marchantia polymorpha [Reaction:R-SHI-1119762] mevalonate kinase - Salvia hispanica [Reaction:R-BJU-1119762] mevalonate kinase - Brassica juncea [Reaction:R-OPU-1119762] mevalonate kinase - Oryza punctata [Reaction:R-OES-1119762] mevalonate kinase - Olea europaea var. sylvestris [Reaction:R-PPE-1119762] mevalonate kinase - Prunus persica [Reaction:R-ACO-1119762] mevalonate kinase - Ananas comosus [Reaction:R-NAT-1119762] mevalonate kinase - Nicotiana attenuata [Reaction:R-CCA-1119762] mevalonate kinase - Cajanus cajan [Reaction:R-TAE-1119762] mevalonate kinase - Triticum aestivum [Reaction:R-QSU-1119762] mevalonate kinase - Quercus suber [Reaction:R-OSI-1119762] mevalonate kinase - Oryza sativa Indica Group [Reaction:R-CBA-1119762] mevalonate kinase - Chara braunii [Reaction:R-HVU-1119762] mevalonate kinase - Hordeum vulgare [Reaction:R-SSP-1119762] mevalonate kinase - Saccharum spontaneum [Reaction:R-AIP-1119762] mevalonate kinase - Arachis ipaensis [Reaction:R-AHY-1119762] mevalonate kinase - Arachis hypogaea [Reaction:R-VVN-1119762] mevalonate kinase - Vitis vinifera [Reaction:R-OBR-1119762] mevalonate kinase - Oryza brachyantha [Reaction:R-ZMY-1119762] mevalonate kinase - Zea mays ver5 [Reaction:R-LST-1119762] mevalonate kinase - Lathyrus sativus [Reaction:R-TUR-1119762] mevalonate kinase - Triticum urartu [Reaction:R-BVU-1119762] mevalonate kinase - Beta vulgaris [Reaction:R-PAB-1119762] mevalonate kinase - Picea abies [Reaction:R-JCU-1119762] mevalonate kinase - Jatropha curcas [Reaction:R-ETE-1119762] mevalonate kinase - Eragrostis tef [Reaction:R-BDI-1119762] mevalonate kinase - Brachypodium distachyon [Reaction:R-PTI-1119762] mevalonate kinase - Populus trichocarpa [Reaction:R-OKA-1119762] mevalonate kinase - Oryza sativa aus subgroup [Reaction:R-CSA-1119762] mevalonate kinase - Cucumis sativus [Reaction:R-PHA-1119762] mevalonate kinase - Panicum hallii ("FIL2") [Reaction:R-ADU-1119762] mevalonate kinase - Arachis duranensis [Reaction:R-TSP-1119762] mevalonate kinase - Triticum spelta subsp. spelta [Reaction:R-HLP-1119762] mevalonate kinase - Humulus lupulus var. lupulus [Reaction:R-BNA-1119762] mevalonate kinase - Brassica napus [Reaction:R-ZMA-1119762] mevalonate kinase - Zea mays [Reaction:R-CCD-1119762] mevalonate kinase - Cynara cardunculus var. scolymus [Reaction:R-OOF-1119762] mevalonate kinase - Oryza officinalis [Reaction:R-OAU-1119762] mevalonate kinase - Oryza australiensis [Reaction:R-PSA-1119762] mevalonate kinase - Pisum sativum [Reaction:R-OEU-1119762] mevalonate kinase - Olea europaea [Reaction:R-CSI-1119762] mevalonate kinase - Citrus sinensis [Reaction:R-NCO-1119762] mevalonate kinase - Nymphaea colorata [Reaction:R-EGR-1119762] mevalonate kinase - Eucalyptus grandis [Reaction:R-ZJA-1119762] mevalonate kinase - Zoysia japonica [Reaction:R-OGL-1119762] mevalonate kinase - Oryza glaberrima [Reaction:R-GSU-1119762] mevalonate kinase - Galdieria sulphuraria [Reaction:R-ECU-1119762] mevalonate kinase - Eragrostis curvula [Reaction:R-CCI-1119762] mevalonate kinase - Corymbia citriodora [Reaction:R-CSC-1119762] mevalonate kinase - Cannabis sativa [Reaction:R-LPE-1119762] mevalonate kinase - Leersia perrieri [Reaction:R-PAV-1119762] mevalonate kinase - Prunus avium [Reaction:R-QLO-1119762] mevalonate kinase - Quercus lobata [Reaction:R-SVI-1119762] mevalonate kinase - Setaria viridis [Reaction:R-SMO-1119762] mevalonate kinase - Selaginella moellendorffii [Reaction:R-CQI-1119762] mevalonate kinase - Chenopodium quinoa [Reaction:R-SIT-1119762] mevalonate kinase - Setaria italica [Reaction:R-GRA-1119762] mevalonate kinase - Gossypium raimondii [Reaction:R-VFA-1119762] mevalonate kinase - Vicia faba var. faba [Reaction:R-MAC-1119762] mevalonate kinase - Musa acuminata [Reaction:R-MES-1119762] mevalonate kinase - Manihot esculenta [Reaction:R-MGU-1119762] mevalonate kinase - Erythranthe guttata [Reaction:R-AUM-1119762] mevalonate kinase - Aegilops umbellulata [Reaction:R-TPR-1119762] mevalonate kinase - Trifolium pratense [Reaction:R-MTR-1119762] mevalonate kinase - Medicago truncatula [Reaction:R-PVU-1119762] mevalonate kinase - Phaseolus vulgaris [Reaction:R-RCH-1119762] mevalonate kinase - Rosa chinensis [Reaction:R-ATH-1119762] mevalonate kinase - Arabidopsis thaliana [Reaction:R-SBI-1119762] mevalonate kinase - Sorghum bicolor [Reaction:R-ITR-1119762] mevalonate kinase - Ipomoea triloba [Reaction:R-ASA-1119762] mevalonate kinase - Avena sativa [Reaction:R-CCN-1119762] mevalonate kinase - Coffea canephora [Reaction:R-PHH-1119762] mevalonate kinase - Panicum hallii var. hallii ("HAL2") [Reaction:R-JRE-1119762] mevalonate kinase - Juglans regia [Reaction:R-ONI-1119762] mevalonate kinase - Oryza nivara [Reaction:R-SIN-1119762] mevalonate kinase - Sesamum indicum [Reaction:R-NNU-1119762] mevalonate kinase - Nelumbo nucifera [Reaction:R-LAN-1119762] mevalonate kinase - Lupinus angustifolius [Reaction:R-ATA-1119762] mevalonate kinase - Aegilops tauschii [Reaction:R-ALY-1119762] mevalonate kinase - Arabidopsis lyrata [Reaction:R-SCR-1119762] mevalonate kinase - Secale cereale [Reaction:R-ATR-1119762] mevalonate kinase - Amborella trichopoda [Reaction:R-FVE-1119762] mevalonate kinase - Fragaria vesca [Reaction:R-VAN-1119762] mevalonate kinase - Vigna angularis [Reaction:R-CLA-1119762] mevalonate kinase - Citrullus lanatus [Reaction:R-BOL-1119762] mevalonate kinase - Brassica oleracea [Reaction:R-CRU-1119762] mevalonate kinase - Capsella rubella [Reaction:R-OGR-1119762] mevalonate kinase - Oryza meyeriana var. granulata
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-191296] MVA5P [cytosol]
precedingEvent	[Reaction:R-OSA-1120896] Hydroxymethylglutaryl-CoA reductase (NADPH) - Oryza sativa
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1119762
summation	[Summation:4790379] (R)-mevalonate is converted to mevalonate-5P by enzymatic ac...

Referrals

(hasEvent)	[Pathway:R-OSA-1119615] Mevalonate pathway - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-1119737] phosphomevalonate kinase - Oryza sativa