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5-oxoprolinase (ATP-hydrolysing)

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catalystActivity	[CatalystActivity:3315088] 5-oxoprolinase (ATP-hydrolyzing) activity of Putative 5-oxoprolinase (LOC_Os01g73514) [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:27727] EC:3.5.2.9 [DatabaseIdentifier:1139882] RiceCyc:5-OXOPROLINASE-ATP-HYDROLYSING-RXN
dbId	1119734
displayName	5-oxoprolinase (ATP-hydrolysing)
eventOf	[Pathway:R-OSA-1119342] Gamma-glutamyl cycle - Oryza sativa
followingEvent	[Reaction:R-OSA-1120528] Glutamate--cysteine ligase - Oryza sativa
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-1247942] OPRO [cytosol]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	5-oxoprolinase (ATP-hydrolysing) 5-OPase 5-oxo-l-prolinase Pyroglutamase (ATP-hydrolysing) biochemicalReaction33077
orthologousEvent	[Reaction:R-LST-1119734] 5-oxoprolinase (ATP-hydrolysing) - Lathyrus sativus [Reaction:R-QLO-1119734] 5-oxoprolinase (ATP-hydrolysing) - Quercus lobata [Reaction:R-ONI-1119734] 5-oxoprolinase (ATP-hydrolysing) - Oryza nivara [Reaction:R-HAN-1119734] 5-oxoprolinase (ATP-hydrolysing) - Helianthus annuus [Reaction:R-TAE-1119734] 5-oxoprolinase (ATP-hydrolysing) - Triticum aestivum [Reaction:R-ORU-1119734] 5-oxoprolinase (ATP-hydrolysing) - Oryza rufipogon [Reaction:R-JCU-1119734] 5-oxoprolinase (ATP-hydrolysing) - Jatropha curcas [Reaction:R-HLP-1119734] 5-oxoprolinase (ATP-hydrolysing) - Humulus lupulus var. lupulus [Reaction:R-NCO-1119734] 5-oxoprolinase (ATP-hydrolysing) - Nymphaea colorata [Reaction:R-OGL-1119734] 5-oxoprolinase (ATP-hydrolysing) - Oryza glaberrima [Reaction:R-OGU-1119734] 5-oxoprolinase (ATP-hydrolysing) - Oryza glumaepatula [Reaction:R-MGU-1119734] 5-oxoprolinase (ATP-hydrolysing) - Erythranthe guttata [Reaction:R-PAV-1119734] 5-oxoprolinase (ATP-hydrolysing) - Prunus avium [Reaction:R-PTI-1119734] 5-oxoprolinase (ATP-hydrolysing) - Populus trichocarpa [Reaction:R-COL-1119734] 5-oxoprolinase (ATP-hydrolysing) - Corchorus olitorius [Reaction:R-CCN-1119734] 5-oxoprolinase (ATP-hydrolysing) - Coffea canephora [Reaction:R-SBI-1119734] 5-oxoprolinase (ATP-hydrolysing) - Sorghum bicolor [Reaction:R-BNA-1119734] 5-oxoprolinase (ATP-hydrolysing) - Brassica napus [Reaction:R-CSC-1119734] 5-oxoprolinase (ATP-hydrolysing) - Cannabis sativa [Reaction:R-VVN-1119734] 5-oxoprolinase (ATP-hydrolysing) - Vitis vinifera [Reaction:R-NNU-1119734] 5-oxoprolinase (ATP-hydrolysing) - Nelumbo nucifera [Reaction:R-OES-1119734] 5-oxoprolinase (ATP-hydrolysing) - Olea europaea var. sylvestris [Reaction:R-TUR-1119734] 5-oxoprolinase (ATP-hydrolysing) - Triticum urartu [Reaction:R-PPA-1119734] 5-oxoprolinase (ATP-hydrolysing) - Physcomitrella patens [Reaction:R-PVE-1119734] 5-oxoprolinase (ATP-hydrolysing) - Pistacia vera [Reaction:R-SIN-1119734] 5-oxoprolinase (ATP-hydrolysing) - Sesamum indicum [Reaction:R-FEX-1119734] 5-oxoprolinase (ATP-hydrolysing) - Fraxinus excelsior (European ash) [Reaction:R-PVU-1119734] 5-oxoprolinase (ATP-hydrolysing) - Phaseolus vulgaris [Reaction:R-ETE-1119734] 5-oxoprolinase (ATP-hydrolysing) - Eragrostis tef [Reaction:R-ACH-1119734] 5-oxoprolinase (ATP-hydrolysing) - Actinidia chinensis [Reaction:R-MAC-1119734] 5-oxoprolinase (ATP-hydrolysing) - Musa acuminata [Reaction:R-CRE-1119734] 5-oxoprolinase (ATP-hydrolysing) - Chlamydomonas reinhardtii [Reaction:R-PHH-1119734] 5-oxoprolinase (ATP-hydrolysing) - Panicum hallii var. hallii ("HAL2") [Reaction:R-JRE-1119734] 5-oxoprolinase (ATP-hydrolysing) - Juglans regia [Reaction:R-ACO-1119734] 5-oxoprolinase (ATP-hydrolysing) - Ananas comosus [Reaction:R-SSP-1119734] 5-oxoprolinase (ATP-hydrolysing) - Saccharum spontaneum [Reaction:R-ECU-1119734] 5-oxoprolinase (ATP-hydrolysing) - Eragrostis curvula [Reaction:R-LPR-1119734] 5-oxoprolinase (ATP-hydrolysing) - Lolium perenne [Reaction:R-NAT-1119734] 5-oxoprolinase (ATP-hydrolysing) - Nicotiana attenuata [Reaction:R-OKA-1119734] 5-oxoprolinase (ATP-hydrolysing) - Oryza sativa aus subgroup [Reaction:R-FVE-1119734] 5-oxoprolinase (ATP-hydrolysing) - Fragaria vesca [Reaction:R-TPR-1119734] 5-oxoprolinase (ATP-hydrolysing) - Trifolium pratense [Reaction:R-ITR-1119734] 5-oxoprolinase (ATP-hydrolysing) - Ipomoea triloba [Reaction:R-CCA-1119734] 5-oxoprolinase (ATP-hydrolysing) - Cajanus cajan [Reaction:R-ALY-1119734] 5-oxoprolinase (ATP-hydrolysing) - Arabidopsis lyrata [Reaction:R-SLY-1119734] 5-oxoprolinase (ATP-hydrolysing) - Solanum lycopersicum [Reaction:R-CME-1119734] 5-oxoprolinase (ATP-hydrolysing) - Cyanidioschyzon merolae [Reaction:R-VUN-1119734] 5-oxoprolinase (ATP-hydrolysing) - Vigna unguiculata [Reaction:R-MPO-1119734] 5-oxoprolinase (ATP-hydrolysing) - Marchantia polymorpha [Reaction:R-CCI-1119734] 5-oxoprolinase (ATP-hydrolysing) - Corymbia citriodora [Reaction:R-DRO-1119734] 5-oxoprolinase (ATP-hydrolysing) - Dioscorea rotundata [Reaction:R-BDI-1119734] 5-oxoprolinase (ATP-hydrolysing) - Brachypodium distachyon [Reaction:R-CLA-1119734] 5-oxoprolinase (ATP-hydrolysing) - Citrullus lanatus [Reaction:R-CAN-1119734] 5-oxoprolinase (ATP-hydrolysing) - Capsicum annuum [Reaction:R-STU-1119734] 5-oxoprolinase (ATP-hydrolysing) - Solanum tuberosum [Reaction:R-TTI-1119734] 5-oxoprolinase (ATP-hydrolysing) - Triticum timopheevii subsp. timopheevii [Reaction:R-GMA-1119734] 5-oxoprolinase (ATP-hydrolysing) - Glycine max [Reaction:R-CST-1119734] 5-oxoprolinase (ATP-hydrolysing) - Camelina sativa [Reaction:R-PPE-1119734] 5-oxoprolinase (ATP-hydrolysing) - Prunus persica [Reaction:R-CAR-1119734] 5-oxoprolinase (ATP-hydrolysing) - Cicer arietinum [Reaction:R-OMI-1119734] 5-oxoprolinase (ATP-hydrolysing) - Oryza minuta [Reaction:R-ASA-1119734] 5-oxoprolinase (ATP-hydrolysing) - Avena sativa [Reaction:R-LPE-1119734] 5-oxoprolinase (ATP-hydrolysing) - Leersia perrieri [Reaction:R-OBA-1119734] 5-oxoprolinase (ATP-hydrolysing) - Oryza barthii [Reaction:R-OLO-1119734] 5-oxoprolinase (ATP-hydrolysing) - Oryza longistaminata [Reaction:R-SVI-1119734] 5-oxoprolinase (ATP-hydrolysing) - Setaria viridis [Reaction:R-VFA-1119734] 5-oxoprolinase (ATP-hydrolysing) - Vicia faba var. faba [Reaction:R-CSA-1119734] 5-oxoprolinase (ATP-hydrolysing) - Cucumis sativus [Reaction:R-BOL-1119734] 5-oxoprolinase (ATP-hydrolysing) - Brassica oleracea [Reaction:R-ADU-1119734] 5-oxoprolinase (ATP-hydrolysing) - Arachis duranensis [Reaction:R-BRA-1119734] 5-oxoprolinase (ATP-hydrolysing) - Brassica rapa [Reaction:R-PED-1119734] 5-oxoprolinase (ATP-hydrolysing) - Phyllostachys edulis [Reaction:R-CCP-1119734] 5-oxoprolinase (ATP-hydrolysing) - Corchorus capsularis [Reaction:R-PHA-1119734] 5-oxoprolinase (ATP-hydrolysing) - Panicum hallii ("FIL2") [Reaction:R-OBR-1119734] 5-oxoprolinase (ATP-hydrolysing) - Oryza brachyantha [Reaction:R-ZJA-1119734] 5-oxoprolinase (ATP-hydrolysing) - Zoysia japonica [Reaction:R-OOF-1119734] 5-oxoprolinase (ATP-hydrolysing) - Oryza officinalis [Reaction:R-CCR-1119734] 5-oxoprolinase (ATP-hydrolysing) - Chondrus crispus [Reaction:R-ATA-1119734] 5-oxoprolinase (ATP-hydrolysing) - Aegilops tauschii [Reaction:R-CSI-1119734] 5-oxoprolinase (ATP-hydrolysing) - Citrus sinensis [Reaction:R-OGR-1119734] 5-oxoprolinase (ATP-hydrolysing) - Oryza meyeriana var. granulata [Reaction:R-OLU-1119734] 5-oxoprolinase (ATP-hydrolysing) - Ostreococcus lucimarinus [Reaction:R-PAB-1119734] 5-oxoprolinase (ATP-hydrolysing) - Picea abies [Reaction:R-OSI-1119734] 5-oxoprolinase (ATP-hydrolysing) - Oryza sativa Indica Group [Reaction:R-FCR-1119734] 5-oxoprolinase (ATP-hydrolysing) - Ficus carica [Reaction:R-SCR-1119734] 5-oxoprolinase (ATP-hydrolysing) - Secale cereale [Reaction:R-TSP-1119734] 5-oxoprolinase (ATP-hydrolysing) - Triticum spelta subsp. spelta [Reaction:R-PSO-1119734] 5-oxoprolinase (ATP-hydrolysing) - Papaver somniferum [Reaction:R-TCA-1119734] 5-oxoprolinase (ATP-hydrolysing) - Theobroma cacao [Reaction:R-EGR-1119734] 5-oxoprolinase (ATP-hydrolysing) - Eucalyptus grandis [Reaction:R-ATR-1119734] 5-oxoprolinase (ATP-hydrolysing) - Amborella trichopoda [Reaction:R-SMO-1119734] 5-oxoprolinase (ATP-hydrolysing) - Selaginella moellendorffii [Reaction:R-VAN-1119734] 5-oxoprolinase (ATP-hydrolysing) - Vigna angularis [Reaction:R-HVU-1119734] 5-oxoprolinase (ATP-hydrolysing) - Hordeum vulgare [Reaction:R-TTU-1119734] 5-oxoprolinase (ATP-hydrolysing) - Triticum turgidum [Reaction:R-MDO-1119734] 5-oxoprolinase (ATP-hydrolysing) - Malus domestica [Reaction:R-OPU-1119734] 5-oxoprolinase (ATP-hydrolysing) - Oryza punctata [Reaction:R-ATH-1119734] 5-oxoprolinase (ATP-hydrolysing) - Arabidopsis thaliana [Reaction:R-LAN-1119734] 5-oxoprolinase (ATP-hydrolysing) - Lupinus angustifolius [Reaction:R-AHY-1119734] 5-oxoprolinase (ATP-hydrolysing) - Arachis hypogaea [Reaction:R-VRA-1119734] 5-oxoprolinase (ATP-hydrolysing) - Vigna radiata [Reaction:R-CCL-1119734] 5-oxoprolinase (ATP-hydrolysing) - Citrus clementina [Reaction:R-AHA-1119734] 5-oxoprolinase (ATP-hydrolysing) - Arabidopsis halleri [Reaction:R-CQI-1119734] 5-oxoprolinase (ATP-hydrolysing) - Chenopodium quinoa [Reaction:R-MTR-1119734] 5-oxoprolinase (ATP-hydrolysing) - Medicago truncatula [Reaction:R-ZMA-1119734] 5-oxoprolinase (ATP-hydrolysing) - Zea mays [Reaction:R-SPC-1119734] 5-oxoprolinase (ATP-hydrolysing) - Synechocystis sp. PCC 6803 [Reaction:R-GRA-1119734] 5-oxoprolinase (ATP-hydrolysing) - Gossypium raimondii [Reaction:R-PDA-1119734] 5-oxoprolinase (ATP-hydrolysing) - Phoenix dactylifera [Reaction:R-MES-1119734] 5-oxoprolinase (ATP-hydrolysing) - Manihot esculenta [Reaction:R-RCH-1119734] 5-oxoprolinase (ATP-hydrolysing) - Rosa chinensis [Reaction:R-CRU-1119734] 5-oxoprolinase (ATP-hydrolysing) - Capsella rubella [Reaction:R-GSO-1119734] 5-oxoprolinase (ATP-hydrolysing) - Glycine soja [Reaction:R-CSK-1119734] 5-oxoprolinase (ATP-hydrolysing) - Cannabis sativa subsp. indica [Reaction:R-SHI-1119734] 5-oxoprolinase (ATP-hydrolysing) - Salvia hispanica [Reaction:R-BVU-1119734] 5-oxoprolinase (ATP-hydrolysing) - Beta vulgaris [Reaction:R-QSU-1119734] 5-oxoprolinase (ATP-hydrolysing) - Quercus suber [Reaction:R-AIP-1119734] 5-oxoprolinase (ATP-hydrolysing) - Arachis ipaensis [Reaction:R-ZMY-1119734] 5-oxoprolinase (ATP-hydrolysing) - Zea mays ver5 [Reaction:R-PTA-1119734] 5-oxoprolinase (ATP-hydrolysing) - Pinus taeda [Reaction:R-GSU-1119734] 5-oxoprolinase (ATP-hydrolysing) - Galdieria sulphuraria [Reaction:R-CCD-1119734] 5-oxoprolinase (ATP-hydrolysing) - Cynara cardunculus var. scolymus [Reaction:R-TDI-1119734] 5-oxoprolinase (ATP-hydrolysing) - Triticum dicoccoides [Reaction:R-AUM-1119734] 5-oxoprolinase (ATP-hydrolysing) - Aegilops umbellulata [Reaction:R-LSA-1119734] 5-oxoprolinase (ATP-hydrolysing) - Lactuca sativa [Reaction:R-SIT-1119734] 5-oxoprolinase (ATP-hydrolysing) - Setaria italica [Reaction:R-CML-1119734] 5-oxoprolinase (ATP-hydrolysing) - Cucumis melo [Reaction:R-PSA-1119734] 5-oxoprolinase (ATP-hydrolysing) - Pisum sativum [Reaction:R-OEU-1119734] 5-oxoprolinase (ATP-hydrolysing) - Olea europaea [Reaction:R-DCA-1119734] 5-oxoprolinase (ATP-hydrolysing) - Daucus carota [Reaction:R-OAU-1119734] 5-oxoprolinase (ATP-hydrolysing) - Oryza australiensis
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-29404] L-Glu [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol]
precedingEvent	[Reaction:R-OSA-1120222] gamma-glutamylcyclotransferase - Oryza sativa
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1119734
summation	[Summation:3315099] 5-oxoproline is converted into L-glutamate by catalytic acti...

Referrals

(hasEvent)	[Pathway:R-OSA-1119342] Gamma-glutamyl cycle - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-1120528] Glutamate--cysteine ligase - Oryza sativa