Plant Reactome Pathway Database - Plant Reactome Pathway Database

Schema > Pathway > Entries

Cholesterol biosynthesis I

Go to Details

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:1153667] RiceCyc:PWY66-341
dbId	1119559
displayName	Cholesterol biosynthesis I
edited	[InstanceEdit:3900246] Beorchia, Dylan, 2013-01-22 [InstanceEdit:3900243] Amarasinghe, V, 2013-06-21
eventOf	[Pathway:R-OSA-3906998] Fatty acid and lipid metabolism - Oryza sativa
goBiologicalProcess	[GO_BiologicalProcess:263684] cholesterol biosynthetic process via lathosterol
hasDiagram	true
hasEvent	[Reaction:R-OSA-1119792] Farnesyl-diphosphate farnesyltransferase - Oryza sativa [Reaction:R-OSA-1120616] presqualene diphosphate+NAD(P)H->squalene+NAD(P)++diphosphate - Oryza sativa [Reaction:R-OSA-1120707] squalene+NADPH+O2->(S)-2,3-Epoxysqualene+NADP++H2O - Oryza sativa [Reaction:R-OSA-1121018] Lanosterol synthase - Oryza sativa [Reaction:R-OSA-1120767] lanosterol+NADPH+O2->4,4-dimethyl-14alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol+NADP++H2O - Oryza sativa [Reaction:R-OSA-1121216] 4,4-dimethyl-14alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol+NADPH+O2->4,4-dimethyl-14alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol+NADP++H2O - Oryza sativa [Reaction:R-OSA-1121474] 4,4-dimethyl-14alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol+NADPH+O2->4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol+NADP++H2O+formate - Oryza sativa [Reaction:R-OSA-1120304] 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol+NADPH->4,4-dimethyl-5alpha-cholesta-8,24-dien-3-beta-ol+NADP+ - Oryza sativa [Reaction:R-OSA-1120472] 4,4-dimethyl-5alpha-cholesta-8,24-dien-3-beta-ol+NAD(P)H+O2->4alpha-hydroxymethyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O - Oryza sativa [Reaction:R-OSA-1121133] 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-formyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O - Oryza sativa [Reaction:R-OSA-1119749] 4alpha-formyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-carboxy-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O - Oryza sativa [Reaction:R-OSA-1120979] 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)+->4alpha-methyl-5alpha-cholesta-8,24-dien-3-one+NAD(P)H+CO2 - Oryza sativa [Reaction:R-OSA-1120411] 4alpha-methyl-5alpha-cholesta-8,24-dien-3-one+NADPH->4-alpha-methyl zymosterol+NADP+ - Oryza sativa [Reaction:R-OSA-1121120] 4-alpha-methyl zymosterol+NAD(P)H+O2->4alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O - Oryza sativa [Reaction:R-OSA-1121309] 4alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O - Oryza sativa [Reaction:R-OSA-1120443] 4alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-carboxy-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O - Oryza sativa [Reaction:R-OSA-1120059] 4alpha-carboxy-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)+->5alpha-cholesta-8,24-dien-3-one+NAD(P)H+CO2 - Oryza sativa [Reaction:R-OSA-1121540] 5alpha-cholesta-8,24-dien-3-one+NADPH->zymosterol+NADP+ - Oryza sativa [Reaction:R-OSA-1121173] zymosterol->5alpha-cholesta-7,24-dien-3beta-ol - Oryza sativa [Reaction:R-OSA-1119926] 5alpha-cholesta-7,24-dien-3beta-ol+NADPH->lathosterol+NADP+ - Oryza sativa [Reaction:R-OSA-1121497] lathosterol+NAD(P)H+O2->7-dehydro-cholesterol+NAD(P)++H2O - Oryza sativa [Reaction:R-OSA-1120741] 7-dehydro-cholesterol+NADPH->cholesterol+NADP+ - Oryza sativa
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	Cholesterol biosynthesis I pathway100403
orthologousEvent	[Pathway:R-COL-1119559] Cholesterol biosynthesis I - Corchorus olitorius [Pathway:R-PAV-1119559] Cholesterol biosynthesis I - Prunus avium [Pathway:R-TSP-1119559] Cholesterol biosynthesis I - Triticum spelta subsp. spelta [Pathway:R-OLO-1119559] Cholesterol biosynthesis I - Oryza longistaminata [Pathway:R-OES-1119559] Cholesterol biosynthesis I - Olea europaea var. sylvestris [Pathway:R-CST-1119559] Cholesterol biosynthesis I - Camelina sativa [Pathway:R-TUR-1119559] Cholesterol biosynthesis I - Triticum urartu [Pathway:R-MDO-1119559] Cholesterol biosynthesis I - Malus domestica [Pathway:R-ACO-1119559] Cholesterol biosynthesis I - Ananas comosus [Pathway:R-SVI-1119559] Cholesterol biosynthesis I - Setaria viridis [Pathway:R-ETE-1119559] Cholesterol biosynthesis I - Eragrostis tef [Pathway:R-OSI-1119559] Cholesterol biosynthesis I - Oryza sativa Indica Group [Pathway:R-ATR-1119559] Cholesterol biosynthesis I - Amborella trichopoda [Pathway:R-CAN-1119559] Cholesterol biosynthesis I - Capsicum annuum [Pathway:R-BJU-1119559] Cholesterol biosynthesis I - Brassica juncea [Pathway:R-ZJA-1119559] Cholesterol biosynthesis I - Zoysia japonica [Pathway:R-SBI-1119559] Cholesterol biosynthesis I - Sorghum bicolor [Pathway:R-TCA-1119559] Cholesterol biosynthesis I - Theobroma cacao [Pathway:R-GSO-1119559] Cholesterol biosynthesis I - Glycine soja [Pathway:R-BRA-1119559] Cholesterol biosynthesis I - Brassica rapa [Pathway:R-CQI-1119559] Cholesterol biosynthesis I - Chenopodium quinoa [Pathway:R-MAC-1119559] Cholesterol biosynthesis I - Musa acuminata [Pathway:R-OGU-1119559] Cholesterol biosynthesis I - Oryza glumaepatula [Pathway:R-CCA-1119559] Cholesterol biosynthesis I - Cajanus cajan [Pathway:R-ADU-1119559] Cholesterol biosynthesis I - Arachis duranensis [Pathway:R-TTU-1119559] Cholesterol biosynthesis I - Triticum turgidum [Pathway:R-PAB-1119559] Cholesterol biosynthesis I - Picea abies [Pathway:R-NAT-1119559] Cholesterol biosynthesis I - Nicotiana attenuata [Pathway:R-DEX-1119559] Cholesterol biosynthesis I - Digitaria exilis [Pathway:R-SHI-1119559] Cholesterol biosynthesis I - Salvia hispanica [Pathway:R-GRA-1119559] Cholesterol biosynthesis I - Gossypium raimondii [Pathway:R-PDA-1119559] Cholesterol biosynthesis I - Phoenix dactylifera [Pathway:R-CLA-1119559] Cholesterol biosynthesis I - Citrullus lanatus [Pathway:R-VRA-1119559] Cholesterol biosynthesis I - Vigna radiata [Pathway:R-SSP-1119559] Cholesterol biosynthesis I - Saccharum spontaneum [Pathway:R-SIN-1119559] Cholesterol biosynthesis I - Sesamum indicum [Pathway:R-LSA-1119559] Cholesterol biosynthesis I - Lactuca sativa [Pathway:R-TAE-1119559] Cholesterol biosynthesis I - Triticum aestivum [Pathway:R-ALY-1119559] Cholesterol biosynthesis I - Arabidopsis lyrata [Pathway:R-OAU-1119559] Cholesterol biosynthesis I - Oryza australiensis [Pathway:R-HLH-1119559] Cholesterol biosynthesis I - Humulus lupulus [Pathway:R-VAN-1119559] Cholesterol biosynthesis I - Vigna angularis [Pathway:R-LPE-1119559] Cholesterol biosynthesis I - Leersia perrieri [Pathway:R-HLP-1119559] Cholesterol biosynthesis I - Humulus lupulus var. lupulus [Pathway:R-ASA-1119559] Cholesterol biosynthesis I - Avena sativa [Pathway:R-NNU-1119559] Cholesterol biosynthesis I - Nelumbo nucifera [Pathway:R-CML-1119559] Cholesterol biosynthesis I - Cucumis melo [Pathway:R-PSA-1119559] Cholesterol biosynthesis I - Pisum sativum [Pathway:R-STU-1119559] Cholesterol biosynthesis I - Solanum tuberosum [Pathway:R-CCN-1119559] Cholesterol biosynthesis I - Coffea canephora [Pathway:R-ZMY-1119559] Cholesterol biosynthesis I - Zea mays ver5 [Pathway:R-CSI-1119559] Cholesterol biosynthesis I - Citrus sinensis [Pathway:R-VVN-1119559] Cholesterol biosynthesis I - Vitis vinifera [Pathway:R-ACH-1119559] Cholesterol biosynthesis I - Actinidia chinensis [Pathway:R-VUN-1119559] Cholesterol biosynthesis I - Vigna unguiculata [Pathway:R-OBR-1119559] Cholesterol biosynthesis I - Oryza brachyantha [Pathway:R-ITR-1119559] Cholesterol biosynthesis I - Ipomoea triloba [Pathway:R-CCD-1119559] Cholesterol biosynthesis I - Cynara cardunculus var. scolymus [Pathway:R-QSU-1119559] Cholesterol biosynthesis I - Quercus suber [Pathway:R-PHA-1119559] Cholesterol biosynthesis I - Panicum hallii ("FIL2") [Pathway:R-GMA-1119559] Cholesterol biosynthesis I - Glycine max [Pathway:R-ATA-1119559] Cholesterol biosynthesis I - Aegilops tauschii [Pathway:R-MTR-1119559] Cholesterol biosynthesis I - Medicago truncatula [Pathway:R-NCO-1119559] Cholesterol biosynthesis I - Nymphaea colorata [Pathway:R-PSO-1119559] Cholesterol biosynthesis I - Papaver somniferum [Pathway:R-PED-1119559] Cholesterol biosynthesis I - Phyllostachys edulis [Pathway:R-CCI-1119559] Cholesterol biosynthesis I - Corymbia citriodora [Pathway:R-OPU-1119559] Cholesterol biosynthesis I - Oryza punctata [Pathway:R-VFA-1119559] Cholesterol biosynthesis I - Vicia faba var. faba [Pathway:R-AUM-1119559] Cholesterol biosynthesis I - Aegilops umbellulata [Pathway:R-CRU-1119559] Cholesterol biosynthesis I - Capsella rubella [Pathway:R-CAR-1119559] Cholesterol biosynthesis I - Cicer arietinum [Pathway:R-OMI-1119559] Cholesterol biosynthesis I - Oryza minuta [Pathway:R-FCR-1119559] Cholesterol biosynthesis I - Ficus carica [Pathway:R-GSU-1119559] Cholesterol biosynthesis I - Galdieria sulphuraria [Pathway:R-BDI-1119559] Cholesterol biosynthesis I - Brachypodium distachyon [Pathway:R-ECU-1119559] Cholesterol biosynthesis I - Eragrostis curvula [Pathway:R-AHA-1119559] Cholesterol biosynthesis I - Arabidopsis halleri [Pathway:R-PPE-1119559] Cholesterol biosynthesis I - Prunus persica [Pathway:R-FVE-1119559] Cholesterol biosynthesis I - Fragaria vesca [Pathway:R-DRO-1119559] Cholesterol biosynthesis I - Dioscorea rotundata [Pathway:R-QLO-1119559] Cholesterol biosynthesis I - Quercus lobata [Pathway:R-AHY-1119559] Cholesterol biosynthesis I - Arachis hypogaea [Pathway:R-CSC-1119559] Cholesterol biosynthesis I - Cannabis sativa [Pathway:R-CME-1119559] Cholesterol biosynthesis I - Cyanidioschyzon merolae [Pathway:R-LST-1119559] Cholesterol biosynthesis I - Lathyrus sativus [Pathway:R-ORU-1119559] Cholesterol biosynthesis I - Oryza rufipogon [Pathway:R-SCR-1119559] Cholesterol biosynthesis I - Secale cereale [Pathway:R-ECG-1119559] Cholesterol biosynthesis I - Echinochloa crus-galli [Pathway:R-BOL-1119559] Cholesterol biosynthesis I - Brassica oleracea [Pathway:R-OLU-1119559] Cholesterol biosynthesis I - Ostreococcus lucimarinus [Pathway:R-ONI-1119559] Cholesterol biosynthesis I - Oryza nivara [Pathway:R-PVU-1119559] Cholesterol biosynthesis I - Phaseolus vulgaris [Pathway:R-CRE-1119559] Cholesterol biosynthesis I - Chlamydomonas reinhardtii [Pathway:R-CSA-1119559] Cholesterol biosynthesis I - Cucumis sativus [Pathway:R-JCU-1119559] Cholesterol biosynthesis I - Jatropha curcas [Pathway:R-CSK-1119559] Cholesterol biosynthesis I - Cannabis sativa subsp. indica [Pathway:R-BNA-1119559] Cholesterol biosynthesis I - Brassica napus [Pathway:R-OGL-1119559] Cholesterol biosynthesis I - Oryza glaberrima [Pathway:R-CBA-1119559] Cholesterol biosynthesis I - Chara braunii [Pathway:R-OME-1119559] Cholesterol biosynthesis I - Oryza meridionalis [Pathway:R-PHH-1119559] Cholesterol biosynthesis I - Panicum hallii var. hallii ("HAL2") [Pathway:R-AOF-1119559] Cholesterol biosynthesis I - Asparagus officinalis [Pathway:R-SPC-1119559] Cholesterol biosynthesis I - Synechocystis sp. PCC 6803 [Pathway:R-OBA-1119559] Cholesterol biosynthesis I - Oryza barthii [Pathway:R-SLY-1119559] Cholesterol biosynthesis I - Solanum lycopersicum [Pathway:R-DCA-1119559] Cholesterol biosynthesis I - Daucus carota [Pathway:R-ATH-1119559] Cholesterol biosynthesis I - Arabidopsis thaliana [Pathway:R-CCP-1119559] Cholesterol biosynthesis I - Corchorus capsularis [Pathway:R-CCL-1119559] Cholesterol biosynthesis I - Citrus clementina [Pathway:R-TDI-1119559] Cholesterol biosynthesis I - Triticum dicoccoides [Pathway:R-RCH-1119559] Cholesterol biosynthesis I - Rosa chinensis [Pathway:R-PTA-1119559] Cholesterol biosynthesis I - Pinus taeda [Pathway:R-LPR-1119559] Cholesterol biosynthesis I - Lolium perenne [Pathway:R-TTI-1119559] Cholesterol biosynthesis I - Triticum timopheevii subsp. timopheevii [Pathway:R-CCR-1119559] Cholesterol biosynthesis I - Chondrus crispus [Pathway:R-MPO-1119559] Cholesterol biosynthesis I - Marchantia polymorpha [Pathway:R-TPR-1119559] Cholesterol biosynthesis I - Trifolium pratense [Pathway:R-HAN-1119559] Cholesterol biosynthesis I - Helianthus annuus [Pathway:R-OGR-1119559] Cholesterol biosynthesis I - Oryza meyeriana var. granulata [Pathway:R-FEX-1119559] Cholesterol biosynthesis I - Fraxinus excelsior (European ash) [Pathway:R-PTI-1119559] Cholesterol biosynthesis I - Populus trichocarpa [Pathway:R-MES-1119559] Cholesterol biosynthesis I - Manihot esculenta [Pathway:R-AIP-1119559] Cholesterol biosynthesis I - Arachis ipaensis [Pathway:R-SIT-1119559] Cholesterol biosynthesis I - Setaria italica [Pathway:R-JRE-1119559] Cholesterol biosynthesis I - Juglans regia [Pathway:R-PVE-1119559] Cholesterol biosynthesis I - Pistacia vera [Pathway:R-MGU-1119559] Cholesterol biosynthesis I - Erythranthe guttata [Pathway:R-EGR-1119559] Cholesterol biosynthesis I - Eucalyptus grandis [Pathway:R-HVU-1119559] Cholesterol biosynthesis I - Hordeum vulgare [Pathway:R-ZMA-1119559] Cholesterol biosynthesis I - Zea mays [Pathway:R-BVU-1119559] Cholesterol biosynthesis I - Beta vulgaris [Pathway:R-SMO-1119559] Cholesterol biosynthesis I - Selaginella moellendorffii [Pathway:R-OOF-1119559] Cholesterol biosynthesis I - Oryza officinalis [Pathway:R-PPA-1119559] Cholesterol biosynthesis I - Physcomitrella patens [Pathway:R-OEU-1119559] Cholesterol biosynthesis I - Olea europaea [Pathway:R-LAN-1119559] Cholesterol biosynthesis I - Lupinus angustifolius
schemaClass	Pathway
species	[Species:186860] Oryza sativa
stId	R-OSA-1119559
summation	[Summation:3900257] cholesterol biosynthesis I [Summation:3900244] Developed by Gramene.org

Referrals

(hasEvent)

[Pathway:R-OSA-3906998] Fatty acid and lipid metabolism - Oryza sativa

© 2019 Gramene - Plant Reactome