Plant Reactome Pathway Database - Plant Reactome Pathway Database

Schema > Pathway > Entries

Sphingolipid metabolism

Go to Details

authored	[InstanceEdit:8854459] Gupta, Parul, 2016-01-27
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:1146033] RiceCyc:SPHINGOLIPID-SYN-PWY
dbId	1119325
displayName	Sphingolipid metabolism
edited	[InstanceEdit:8854459] Gupta, Parul, 2016-01-27
eventOf	[Pathway:R-OSA-3906998] Fatty acid and lipid metabolism - Oryza sativa
goBiologicalProcess	[GO_BiologicalProcess:5272] sphingolipid metabolic process
hasDiagram	true
hasEvent	[Reaction:R-OSA-9025528] Formation of ceramide 1-phosphate - Oryza sativa [Reaction:R-OSA-9025495] Formation of phytoceramide - Oryza sativa [Reaction:R-OSA-1120287] Formation of SPAP - Oryza sativa [Reaction:R-OSA-9025489] Formation of CERA - Oryza sativa [Reaction:R-OSA-9025506] Formation of dihydroceramide - Oryza sativa [Reaction:R-OSA-1121356] Formation of phosphoethanolamine - Oryza sativa [Reaction:R-OSA-9025522] Formation of 3-ketosphinganine - Oryza sativa [Reaction:R-OSA-9025467] Formation of sphinganine - Oryza sativa
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5308372] Functional characterization of a higher plant sphingolipid Delta4-desaturase: defining the role of sphingosine and sphingosine-1-phosphate in Arabidopsis [LiteratureReference:5308006] Characterization of an Arabidopsis cDNA encoding a subunit of serine palmitoyltransferase, the initial enzyme in sphingolipid biosynthesis [LiteratureReference:9025440] Serine palmitoyltransferase, a key enzyme for de novo synthesis of sphingolipids, is essential for male gametophyte development in Arabidopsis [LiteratureReference:9025486] Unraveling the roles of sphingolipids in plant innate immunity [LiteratureReference:9025532] Sphingolipids containing very-long-chain fatty acids define a secretory pathway for specific polar plasma membrane protein targeting in Arabidopsis [LiteratureReference:5307909] Sphingolipids in the root play an important role in regulating the leaf ionome in Arabidopsis thaliana [LiteratureReference:9025535] Deciphering the link between salicylic acid signaling and sphingolipid metabolism [LiteratureReference:9025490] Formation of glucosylceramide and sterol glucoside by a UDP-glucose-dependent glucosylceramide synthase from cotton expressed in Pichia pastoris [LiteratureReference:5307911] Ceramides modulate programmed cell death in plants [LiteratureReference:5308024] Functional characterization of sphingolipid C4-hydroxylase genes from Arabidopsis thaliana [LiteratureReference:5308371] An inositolphosphorylceramide synthase is involved in regulation of plant programmed cell death associated with defense in Arabidopsis [LiteratureReference:5308397] Involvement of sphingosine kinase in plant cell signalling [LiteratureReference:9025464] Arabidopsis mutants of sphingolipid fatty acid ?-hydroxylases accumulate ceramides and salicylates [LiteratureReference:9025480] The essential nature of sphingolipids in plants as revealed by the functional identification and characterization of the Arabidopsis LCB1 subunit of serine palmitoyltransferase [LiteratureReference:9025550] Molecular characterization and targeted quantitative profiling of the sphingolipidome in rice [LiteratureReference:9025507] Molecular Characterization of Rice OsLCB2a1 Gene and Functional Analysis of its Role in Insect Resistance [LiteratureReference:9025478] Molecular characterization of rice sphingosine-1-phosphate lyase gene OsSPL1 and functional analysis of its role in disease resistance response
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	Sphingolipid metabolism pathway100864
orthologousEvent	[Pathway:R-HVU-1119325] Sphingolipid metabolism - Hordeum vulgare [Pathway:R-CAN-1119325] Sphingolipid metabolism - Capsicum annuum [Pathway:R-PSO-1119325] Sphingolipid metabolism - Papaver somniferum [Pathway:R-QSU-1119325] Sphingolipid metabolism - Quercus suber [Pathway:R-OBA-1119325] Sphingolipid metabolism - Oryza barthii [Pathway:R-TUR-1119325] Sphingolipid metabolism - Triticum urartu [Pathway:R-BVU-1119325] Sphingolipid metabolism - Beta vulgaris [Pathway:R-DRO-1119325] Sphingolipid metabolism - Dioscorea rotundata [Pathway:R-ZJA-1119325] Sphingolipid metabolism - Zoysia japonica [Pathway:R-NAT-1119325] Sphingolipid metabolism - Nicotiana attenuata [Pathway:R-LPE-1119325] Sphingolipid metabolism - Leersia perrieri [Pathway:R-DCA-1119325] Sphingolipid metabolism - Daucus carota [Pathway:R-AHA-1119325] Sphingolipid metabolism - Arabidopsis halleri [Pathway:R-SLY-1119325] Sphingolipid metabolism - Solanum lycopersicum [Pathway:R-GSU-1119325] Sphingolipid metabolism - Galdieria sulphuraria [Pathway:R-VAN-1119325] Sphingolipid metabolism - Vigna angularis [Pathway:R-BDI-1119325] Sphingolipid metabolism - Brachypodium distachyon [Pathway:R-CAR-1119325] Sphingolipid metabolism - Cicer arietinum [Pathway:R-SCR-1119325] Sphingolipid metabolism - Secale cereale [Pathway:R-OGL-1119325] Sphingolipid metabolism - Oryza glaberrima [Pathway:R-CSA-1119325] Sphingolipid metabolism - Cucumis sativus [Pathway:R-VFA-1119325] Sphingolipid metabolism - Vicia faba var. faba [Pathway:R-CSI-1119325] Sphingolipid metabolism - Citrus sinensis [Pathway:R-BOL-1119325] Sphingolipid metabolism - Brassica oleracea [Pathway:R-VUN-1119325] Sphingolipid metabolism - Vigna unguiculata [Pathway:R-OBR-1119325] Sphingolipid metabolism - Oryza brachyantha [Pathway:R-STU-1119325] Sphingolipid metabolism - Solanum tuberosum [Pathway:R-CCA-1119325] Sphingolipid metabolism - Cajanus cajan [Pathway:R-PHA-1119325] Sphingolipid metabolism - Panicum hallii ("FIL2") [Pathway:R-MAC-1119325] Sphingolipid metabolism - Musa acuminata [Pathway:R-BJU-1119325] Sphingolipid metabolism - Brassica juncea [Pathway:R-GSO-1119325] Sphingolipid metabolism - Glycine soja [Pathway:R-JCU-1119325] Sphingolipid metabolism - Jatropha curcas [Pathway:R-CRE-1119325] Sphingolipid metabolism - Chlamydomonas reinhardtii [Pathway:R-FCR-1119325] Sphingolipid metabolism - Ficus carica [Pathway:R-CCI-1119325] Sphingolipid metabolism - Corymbia citriodora [Pathway:R-OGU-1119325] Sphingolipid metabolism - Oryza glumaepatula [Pathway:R-MPO-1119325] Sphingolipid metabolism - Marchantia polymorpha [Pathway:R-OGR-1119325] Sphingolipid metabolism - Oryza meyeriana var. granulata [Pathway:R-PPE-1119325] Sphingolipid metabolism - Prunus persica [Pathway:R-SBI-1119325] Sphingolipid metabolism - Sorghum bicolor [Pathway:R-LAN-1119325] Sphingolipid metabolism - Lupinus angustifolius [Pathway:R-OOF-1119325] Sphingolipid metabolism - Oryza officinalis [Pathway:R-TDI-1119325] Sphingolipid metabolism - Triticum dicoccoides [Pathway:R-RCH-1119325] Sphingolipid metabolism - Rosa chinensis [Pathway:R-PTA-1119325] Sphingolipid metabolism - Pinus taeda [Pathway:R-SVI-1119325] Sphingolipid metabolism - Setaria viridis [Pathway:R-OKA-1119325] Sphingolipid metabolism - Oryza sativa aus subgroup [Pathway:R-PSA-1119325] Sphingolipid metabolism - Pisum sativum [Pathway:R-GRA-1119325] Sphingolipid metabolism - Gossypium raimondii [Pathway:R-HLP-1119325] Sphingolipid metabolism - Humulus lupulus var. lupulus [Pathway:R-HLH-1119325] Sphingolipid metabolism - Humulus lupulus [Pathway:R-CST-1119325] Sphingolipid metabolism - Camelina sativa [Pathway:R-BNA-1119325] Sphingolipid metabolism - Brassica napus [Pathway:R-ATR-1119325] Sphingolipid metabolism - Amborella trichopoda [Pathway:R-VVN-1119325] Sphingolipid metabolism - Vitis vinifera [Pathway:R-MTR-1119325] Sphingolipid metabolism - Medicago truncatula [Pathway:R-OLO-1119325] Sphingolipid metabolism - Oryza longistaminata [Pathway:R-TSP-1119325] Sphingolipid metabolism - Triticum spelta subsp. spelta [Pathway:R-CCR-1119325] Sphingolipid metabolism - Chondrus crispus [Pathway:R-CCL-1119325] Sphingolipid metabolism - Citrus clementina [Pathway:R-MDO-1119325] Sphingolipid metabolism - Malus domestica [Pathway:R-SSP-1119325] Sphingolipid metabolism - Saccharum spontaneum [Pathway:R-DEX-1119325] Sphingolipid metabolism - Digitaria exilis [Pathway:R-ATA-1119325] Sphingolipid metabolism - Aegilops tauschii [Pathway:R-OPU-1119325] Sphingolipid metabolism - Oryza punctata [Pathway:R-TCA-1119325] Sphingolipid metabolism - Theobroma cacao [Pathway:R-SMO-1119325] Sphingolipid metabolism - Selaginella moellendorffii [Pathway:R-ECU-1119325] Sphingolipid metabolism - Eragrostis curvula [Pathway:R-LSA-1119325] Sphingolipid metabolism - Lactuca sativa [Pathway:R-PHH-1119325] Sphingolipid metabolism - Panicum hallii var. hallii ("HAL2") [Pathway:R-CLA-1119325] Sphingolipid metabolism - Citrullus lanatus [Pathway:R-CBA-1119325] Sphingolipid metabolism - Chara braunii [Pathway:R-AUM-1119325] Sphingolipid metabolism - Aegilops umbellulata [Pathway:R-OEU-1119325] Sphingolipid metabolism - Olea europaea [Pathway:R-CSK-1119325] Sphingolipid metabolism - Cannabis sativa subsp. indica [Pathway:R-FVE-1119325] Sphingolipid metabolism - Fragaria vesca [Pathway:R-SIN-1119325] Sphingolipid metabolism - Sesamum indicum [Pathway:R-ACO-1119325] Sphingolipid metabolism - Ananas comosus [Pathway:R-ASA-1119325] Sphingolipid metabolism - Avena sativa [Pathway:R-OAU-1119325] Sphingolipid metabolism - Oryza australiensis [Pathway:R-AHY-1119325] Sphingolipid metabolism - Arachis hypogaea [Pathway:R-CME-1119325] Sphingolipid metabolism - Cyanidioschyzon merolae [Pathway:R-PPA-1119325] Sphingolipid metabolism - Physcomitrella patens [Pathway:R-ECG-1119325] Sphingolipid metabolism - Echinochloa crus-galli [Pathway:R-ORU-1119325] Sphingolipid metabolism - Oryza rufipogon [Pathway:R-PTI-1119325] Sphingolipid metabolism - Populus trichocarpa [Pathway:R-CSC-1119325] Sphingolipid metabolism - Cannabis sativa [Pathway:R-MES-1119325] Sphingolipid metabolism - Manihot esculenta [Pathway:R-CML-1119325] Sphingolipid metabolism - Cucumis melo [Pathway:R-FEX-1119325] Sphingolipid metabolism - Fraxinus excelsior (European ash) [Pathway:R-SPC-1119325] Sphingolipid metabolism - Synechocystis sp. PCC 6803 [Pathway:R-MGU-1119325] Sphingolipid metabolism - Erythranthe guttata [Pathway:R-QLO-1119325] Sphingolipid metabolism - Quercus lobata [Pathway:R-ACH-1119325] Sphingolipid metabolism - Actinidia chinensis [Pathway:R-ITR-1119325] Sphingolipid metabolism - Ipomoea triloba [Pathway:R-JRE-1119325] Sphingolipid metabolism - Juglans regia [Pathway:R-PVU-1119325] Sphingolipid metabolism - Phaseolus vulgaris [Pathway:R-ADU-1119325] Sphingolipid metabolism - Arachis duranensis [Pathway:R-CCD-1119325] Sphingolipid metabolism - Cynara cardunculus var. scolymus [Pathway:R-TTU-1119325] Sphingolipid metabolism - Triticum turgidum [Pathway:R-PED-1119325] Sphingolipid metabolism - Phyllostachys edulis [Pathway:R-VRA-1119325] Sphingolipid metabolism - Vigna radiata [Pathway:R-GMA-1119325] Sphingolipid metabolism - Glycine max [Pathway:R-PVE-1119325] Sphingolipid metabolism - Pistacia vera [Pathway:R-BRA-1119325] Sphingolipid metabolism - Brassica rapa [Pathway:R-PDA-1119325] Sphingolipid metabolism - Phoenix dactylifera [Pathway:R-NCO-1119325] Sphingolipid metabolism - Nymphaea colorata [Pathway:R-ZMA-1119325] Sphingolipid metabolism - Zea mays [Pathway:R-EGR-1119325] Sphingolipid metabolism - Eucalyptus grandis [Pathway:R-CCN-1119325] Sphingolipid metabolism - Coffea canephora [Pathway:R-SHI-1119325] Sphingolipid metabolism - Salvia hispanica [Pathway:R-ATH-1119325] Sphingolipid metabolism - Arabidopsis thaliana [Pathway:R-OMI-1119325] Sphingolipid metabolism - Oryza minuta [Pathway:R-TAE-1119325] Sphingolipid metabolism - Triticum aestivum [Pathway:R-CCP-1119325] Sphingolipid metabolism - Corchorus capsularis [Pathway:R-LST-1119325] Sphingolipid metabolism - Lathyrus sativus [Pathway:R-ALY-1119325] Sphingolipid metabolism - Arabidopsis lyrata [Pathway:R-COL-1119325] Sphingolipid metabolism - Corchorus olitorius [Pathway:R-HAN-1119325] Sphingolipid metabolism - Helianthus annuus [Pathway:R-TPR-1119325] Sphingolipid metabolism - Trifolium pratense [Pathway:R-NNU-1119325] Sphingolipid metabolism - Nelumbo nucifera [Pathway:R-OSI-1119325] Sphingolipid metabolism - Oryza sativa Indica Group [Pathway:R-PAV-1119325] Sphingolipid metabolism - Prunus avium [Pathway:R-ONI-1119325] Sphingolipid metabolism - Oryza nivara [Pathway:R-CRU-1119325] Sphingolipid metabolism - Capsella rubella [Pathway:R-ZMY-1119325] Sphingolipid metabolism - Zea mays ver5 [Pathway:R-TTI-1119325] Sphingolipid metabolism - Triticum timopheevii subsp. timopheevii [Pathway:R-CQI-1119325] Sphingolipid metabolism - Chenopodium quinoa [Pathway:R-LPR-1119325] Sphingolipid metabolism - Lolium perenne [Pathway:R-OES-1119325] Sphingolipid metabolism - Olea europaea var. sylvestris [Pathway:R-SIT-1119325] Sphingolipid metabolism - Setaria italica [Pathway:R-ETE-1119325] Sphingolipid metabolism - Eragrostis tef [Pathway:R-OLU-1119325] Sphingolipid metabolism - Ostreococcus lucimarinus [Pathway:R-AOF-1119325] Sphingolipid metabolism - Asparagus officinalis [Pathway:R-PAB-1119325] Sphingolipid metabolism - Picea abies [Pathway:R-OME-1119325] Sphingolipid metabolism - Oryza meridionalis [Pathway:R-AIP-1119325] Sphingolipid metabolism - Arachis ipaensis
revised	[InstanceEdit:8854459] Gupta, Parul, 2016-01-27
schemaClass	Pathway
species	[Species:186860] Oryza sativa
stId	R-OSA-1119325
summation	[Summation:9025476] Sphingolipids compose ?40% of the lipids of the plasma membr... [Summation:1119236] Data source: RiceCyc

Referrals

(hasEvent)

[Pathway:R-OSA-3906998] Fatty acid and lipid metabolism - Oryza sativa