Plant Reactome Pathway Database - Plant Reactome Pathway Database

Schema > GO_BiologicalProcess > Entries

accession	0006540
databaseName	GO
dbId	19348
definition	The chemical reactions and pathways resulting in the formation of succinate from glutamate. Also known as GABA (gamma-aminobutyrate) shunt since it channels glutamate into the TCA cycle bypassing two steps of that cycle. There are three enzymes involved in the GABA shunt: glutamate decarboxylase (GAD), GABA aminotransferase (GABA-TA), and succinate semialdehyde dehydrogenase (SSADH). These three enzymes acting in concert to convert glutamate into succinate. The GABA shunt is predominantly associated with neurotransmission in the mammalian brain. It is also present in nonneuronal cells, in plants, in unicellular eukaryotes, and in prokaryotes.
displayName	gamma-aminobutyrate shunt
modified	[InstanceEdit:9676538] Cook, Justin, 2020-02-17
name	gamma-aminobutyrate shunt
referenceDatabase	[ReferenceDatabase:1] GO
schemaClass	GO_BiologicalProcess
url	https://www.ebi.ac.uk/QuickGO/term/GO:0006540

(goBiologicalProcess)