Assembly of pre-replication complex

Stable Identifier
R-OSA-9640882
Type
Pathway
Species
Oryza sativa
Compartment
Locations in the PathwayBrowser
Summation

In G1/S phase, formation of pre-replication complex (Pre-RC) takes place. The first step of the pre-RC assembly is the binding of ORCs to DNA. In presence of ATP (non-hydrolysable) ORCs bind tightly with chromosomal replication origins followed by recruitment of Cdc6, CDT1 and the MCM2-7 heterohexamer onto dsDNA.

Participants
Participant Of
hasEvent
Orthologous Events