{
  "dbId" : 9861670,
  "stableId" : "R-ACO-8879007",
  "displayName" : "Response to cold temperature",
  "nodes" : [ {
    "id" : 10336,
    "reactomeId" : 9859263,
    "displayName" : "Aco004913.1.path1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 723,
      "y" : 584
    },
    "minX" : 673,
    "maxX" : 780,
    "minY" : 567,
    "maxY" : 595,
    "prop" : {
      "x" : 673,
      "y" : 573,
      "width" : 101,
      "height" : 22
    },
    "textPosition" : {
      "x" : 681,
      "y" : 566
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 774,
          "y" : 573
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true
      }
    },
    "connectors" : [ {
      "edgeId" : 10335,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 10338,
    "reactomeId" : 9859299,
    "displayName" : "Aco014818.1.path1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 319,
      "y" : 668
    },
    "minX" : 299,
    "maxX" : 345,
    "minY" : 651,
    "maxY" : 679,
    "prop" : {
      "x" : 299,
      "y" : 657,
      "width" : 40,
      "height" : 22
    },
    "textPosition" : {
      "x" : 299,
      "y" : 636
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 339,
          "y" : 657
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true
      }
    },
    "connectors" : [ {
      "edgeId" : 10337,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 10340,
    "reactomeId" : 9859293,
    "displayName" : "Aco007644.1.path1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 316,
      "y" : 731
    },
    "minX" : 301,
    "maxX" : 337,
    "minY" : 714,
    "maxY" : 742,
    "prop" : {
      "x" : 301,
      "y" : 720,
      "width" : 30,
      "height" : 22
    },
    "textPosition" : {
      "x" : 301,
      "y" : 685
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 331,
          "y" : 720
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true
      }
    },
    "connectors" : [ {
      "edgeId" : 10339,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 10345,
    "reactomeId" : 8879025,
    "displayName" : "cold temperature",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 245,
      "y" : 19
    },
    "minX" : 181,
    "maxX" : 310,
    "minY" : 3,
    "maxY" : 34,
    "prop" : {
      "x" : 181,
      "y" : 4,
      "width" : 128,
      "height" : 30
    },
    "textPosition" : {
      "x" : 195,
      "y" : 8
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 304,
          "y" : 9
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true
      }
    },
    "connectors" : [ ]
  }, {
    "id" : 10330,
    "reactomeId" : 9859287,
    "displayName" : "Aco013937.1.path1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 446,
      "y" : 486
    },
    "minX" : 395,
    "maxX" : 578,
    "minY" : 469,
    "maxY" : 497,
    "prop" : {
      "x" : 395,
      "y" : 475,
      "width" : 102,
      "height" : 22
    },
    "textPosition" : {
      "x" : 404,
      "y" : 468
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 497,
          "y" : 475
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true
      }
    },
    "connectors" : [ {
      "edgeId" : 10329,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 10333,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 500,
          "y" : 486
        },
        "to" : {
          "x" : 578,
          "y" : 487
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 578,
          "y" : 491
        },
        "b" : {
          "x" : 578,
          "y" : 483
        },
        "c" : {
          "x" : 578,
          "y" : 487
        },
        "type" : "STOP"
      }
    } ]
  }, {
    "id" : 10332,
    "reactomeId" : 9859279,
    "displayName" : "Aco020962.1.path1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 788,
      "y" : 471
    },
    "minX" : 732,
    "maxX" : 834,
    "minY" : 460,
    "maxY" : 539,
    "prop" : {
      "x" : 743,
      "y" : 460,
      "width" : 91,
      "height" : 22
    },
    "textPosition" : {
      "x" : 746,
      "y" : 453
    },
    "connectors" : [ {
      "edgeId" : 10331,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 10335,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 787,
          "y" : 488
        },
        "to" : {
          "x" : 787,
          "y" : 535
        }
      }, {
        "from" : {
          "x" : 787,
          "y" : 535
        },
        "to" : {
          "x" : 732,
          "y" : 535
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 732,
          "y" : 539
        },
        "b" : {
          "x" : 732,
          "y" : 531
        },
        "c" : {
          "x" : 732,
          "y" : 535
        },
        "type" : "STOP"
      }
    } ]
  }, {
    "id" : 10334,
    "reactomeId" : 9859275,
    "displayName" : "CBF1 homolog",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 587,
      "y" : 535
    },
    "minX" : 542,
    "maxX" : 714,
    "minY" : 520,
    "maxY" : 551,
    "prop" : {
      "x" : 542,
      "y" : 520,
      "width" : 91,
      "height" : 31
    },
    "textPosition" : {
      "x" : 543,
      "y" : 524
    },
    "connectors" : [ {
      "edgeId" : 10333,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 10335,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 639,
          "y" : 535
        },
        "to" : {
          "x" : 714,
          "y" : 535
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 714,
          "y" : 539
        },
        "b" : {
          "x" : 714,
          "y" : 531
        },
        "c" : {
          "x" : 714,
          "y" : 535
        },
        "type" : "STOP"
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 10337,
    "reactomeId" : 9859301,
    "displayName" : "expression of CTB1",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 266,
      "y" : 668
    },
    "minX" : 231,
    "maxX" : 296,
    "minY" : 662,
    "maxY" : 674,
    "segments" : [ {
      "from" : {
        "x" : 231,
        "y" : 668
      },
      "to" : {
        "x" : 266,
        "y" : 668
      }
    }, {
      "from" : {
        "x" : 266,
        "y" : 668
      },
      "to" : {
        "x" : 296,
        "y" : 668
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 289,
        "y" : 672
      },
      "b" : {
        "x" : 296,
        "y" : 668
      },
      "c" : {
        "x" : 289,
        "y" : 664
      },
      "type" : "ARROW"
    },
    "reactionShape" : {
      "a" : {
        "x" : 260,
        "y" : 662
      },
      "b" : {
        "x" : 272,
        "y" : 674
      },
      "type" : "BOX",
      "empty" : true
    },
    "outputs" : [ {
      "id" : 10338
    } ]
  }, {
    "id" : 10339,
    "reactomeId" : 9859295,
    "displayName" : "expression of FR6",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 265,
      "y" : 730
    },
    "minX" : 226,
    "maxX" : 298,
    "minY" : 724,
    "maxY" : 736,
    "segments" : [ {
      "from" : {
        "x" : 226,
        "y" : 730
      },
      "to" : {
        "x" : 265,
        "y" : 730
      }
    }, {
      "from" : {
        "x" : 265,
        "y" : 730
      },
      "to" : {
        "x" : 298,
        "y" : 730
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 291,
        "y" : 734
      },
      "b" : {
        "x" : 298,
        "y" : 730
      },
      "c" : {
        "x" : 291,
        "y" : 726
      },
      "type" : "ARROW"
    },
    "reactionShape" : {
      "a" : {
        "x" : 259,
        "y" : 724
      },
      "b" : {
        "x" : 271,
        "y" : 736
      },
      "type" : "BOX",
      "empty" : true
    },
    "outputs" : [ {
      "id" : 10340
    } ]
  }, {
    "id" : 10329,
    "reactomeId" : 9859289,
    "displayName" : "expression of MYB15 homolog",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 446,
      "y" : 441
    },
    "minX" : 440,
    "maxX" : 452,
    "minY" : 412,
    "maxY" : 472,
    "segments" : [ {
      "from" : {
        "x" : 446,
        "y" : 412
      },
      "to" : {
        "x" : 446,
        "y" : 441
      }
    }, {
      "from" : {
        "x" : 446,
        "y" : 441
      },
      "to" : {
        "x" : 446,
        "y" : 472
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 442,
        "y" : 465
      },
      "b" : {
        "x" : 446,
        "y" : 472
      },
      "c" : {
        "x" : 450,
        "y" : 465
      },
      "type" : "ARROW"
    },
    "reactionShape" : {
      "a" : {
        "x" : 440,
        "y" : 435
      },
      "b" : {
        "x" : 452,
        "y" : 447
      },
      "type" : "BOX",
      "empty" : true
    },
    "outputs" : [ {
      "id" : 10330
    } ]
  }, {
    "id" : 10331,
    "reactomeId" : 9859303,
    "displayName" : "expression of LOS2 homolog",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 868,
      "y" : 469
    },
    "minX" : 840,
    "maxX" : 892,
    "minY" : 463,
    "maxY" : 475,
    "segments" : [ {
      "from" : {
        "x" : 892,
        "y" : 469
      },
      "to" : {
        "x" : 868,
        "y" : 469
      }
    }, {
      "from" : {
        "x" : 868,
        "y" : 469
      },
      "to" : {
        "x" : 840,
        "y" : 469
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 847,
        "y" : 465
      },
      "b" : {
        "x" : 840,
        "y" : 469
      },
      "c" : {
        "x" : 847,
        "y" : 473
      },
      "type" : "ARROW"
    },
    "reactionShape" : {
      "a" : {
        "x" : 862,
        "y" : 463
      },
      "b" : {
        "x" : 874,
        "y" : 475
      },
      "type" : "BOX",
      "empty" : true
    },
    "outputs" : [ {
      "id" : 10332
    } ]
  }, {
    "id" : 10333,
    "reactomeId" : 9859305,
    "displayName" : "expression of CBF1 homolog",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 587,
      "y" : 487
    },
    "minX" : 581,
    "maxX" : 593,
    "minY" : 425,
    "maxY" : 514,
    "segments" : [ {
      "from" : {
        "x" : 587,
        "y" : 425
      },
      "to" : {
        "x" : 587,
        "y" : 487
      }
    }, {
      "from" : {
        "x" : 587,
        "y" : 487
      },
      "to" : {
        "x" : 587,
        "y" : 514
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 583,
        "y" : 507
      },
      "b" : {
        "x" : 587,
        "y" : 514
      },
      "c" : {
        "x" : 591,
        "y" : 507
      },
      "type" : "ARROW"
    },
    "reactionShape" : {
      "a" : {
        "x" : 581,
        "y" : 481
      },
      "b" : {
        "x" : 593,
        "y" : 493
      },
      "type" : "BOX",
      "empty" : true
    },
    "outputs" : [ {
      "id" : 10334
    } ],
    "inhibitors" : [ {
      "id" : 10330,
      "points" : [ {
        "x" : 500,
        "y" : 486
      } ]
    } ]
  }, {
    "id" : 10335,
    "reactomeId" : 9859281,
    "displayName" : "expression of ZAT10 homolog",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 723,
      "y" : 535
    },
    "minX" : 717,
    "maxX" : 729,
    "minY" : 503,
    "maxY" : 570,
    "segments" : [ {
      "from" : {
        "x" : 723,
        "y" : 503
      },
      "to" : {
        "x" : 723,
        "y" : 535
      }
    }, {
      "from" : {
        "x" : 723,
        "y" : 535
      },
      "to" : {
        "x" : 723,
        "y" : 570
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 719,
        "y" : 563
      },
      "b" : {
        "x" : 723,
        "y" : 570
      },
      "c" : {
        "x" : 727,
        "y" : 563
      },
      "type" : "ARROW"
    },
    "reactionShape" : {
      "a" : {
        "x" : 717,
        "y" : 529
      },
      "b" : {
        "x" : 729,
        "y" : 541
      },
      "type" : "BOX",
      "empty" : true
    },
    "outputs" : [ {
      "id" : 10336
    } ],
    "inhibitors" : [ {
      "id" : 10332,
      "points" : [ {
        "x" : 787,
        "y" : 488
      }, {
        "x" : 787,
        "y" : 535
      } ]
    }, {
      "id" : 10334,
      "points" : [ {
        "x" : 639,
        "y" : 535
      } ]
    } ]
  } ],
  "compartments" : [ {
    "id" : 10342,
    "reactomeId" : 7660,
    "displayName" : "nucleoplasm",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 519,
      "y" : 501
    },
    "minX" : 79,
    "maxX" : 959,
    "minY" : 247,
    "maxY" : 755,
    "prop" : {
      "x" : 79,
      "y" : 247,
      "width" : 880,
      "height" : 508
    },
    "textPosition" : {
      "x" : 843,
      "y" : 710
    },
    "insets" : {
      "x" : 89,
      "y" : 257,
      "width" : 860,
      "height" : 488
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 10334, 10336, 10332, 10330, 10338, 10340, 10329, 10331, 10333, 10335, 10346, 10337, 10339, 10347 ]
  }, {
    "id" : 10343,
    "reactomeId" : 876,
    "displayName" : "plasma membrane",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 538,
      "y" : 458
    },
    "minX" : 27,
    "maxX" : 1049,
    "minY" : 86,
    "maxY" : 831,
    "prop" : {
      "x" : 27,
      "y" : 86,
      "width" : 1022,
      "height" : 745
    },
    "textPosition" : {
      "x" : 916,
      "y" : 89
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 10344 ]
  }, {
    "id" : 10344,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 540,
      "y" : 471
    },
    "minX" : 44,
    "maxX" : 1037,
    "minY" : 121,
    "maxY" : 822,
    "prop" : {
      "x" : 44,
      "y" : 121,
      "width" : 993,
      "height" : 701
    },
    "textPosition" : {
      "x" : 962,
      "y" : 134
    },
    "insets" : {
      "x" : 54,
      "y" : 131,
      "width" : 973,
      "height" : 681
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 10342, 10348 ]
  } ],
  "notes" : [ ],
  "links" : [ ],
  "shadows" : [ ],
  "minX" : 27,
  "maxX" : 1049,
  "minY" : 3,
  "maxY" : 831,
  "disease" : false
}