{
  "dbId" : 1112991,
  "stableId" : "R-OSA-1112991",
  "displayName" : "Diagram of Translation termination",
  "nodes" : [ {
    "id" : 960,
    "reactomeId" : 1115169,
    "displayName" : "eRF3-GTP:eRF1:80S Ribosome:mRNA:peptidyl-tRNA Complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 397,
      "y" : 156
    },
    "minX" : 334,
    "maxX" : 461,
    "minY" : 103,
    "maxY" : 209,
    "prop" : {
      "x" : 334,
      "y" : 103,
      "width" : 127,
      "height" : 106
    },
    "textPosition" : {
      "x" : 337,
      "y" : 117
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "connectors" : [ {
      "edgeId" : 955,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 956,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 961,
    "reactomeId" : 1115128,
    "displayName" : "eRF3-GDP:eRF1:80S Ribosome:mRNA:tRNA Complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 411,
      "y" : 407
    },
    "minX" : 346,
    "maxX" : 570,
    "minY" : 361,
    "maxY" : 453,
    "prop" : {
      "x" : 346,
      "y" : 361,
      "width" : 131,
      "height" : 92
    },
    "textPosition" : {
      "x" : 348,
      "y" : 375
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "connectors" : [ {
      "edgeId" : 962,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 480,
          "y" : 399
        },
        "to" : {
          "x" : 570,
          "y" : 390
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 486,
          "y" : 394
        },
        "b" : {
          "x" : 480,
          "y" : 399
        },
        "c" : {
          "x" : 487,
          "y" : 402
        },
        "type" : "ARROW"
      }
    } ]
  }, {
    "id" : 952,
    "reactomeId" : 1115088,
    "displayName" : "80S Ribosome:mRNA:peptidyl-tRNA with elongating peptide",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 131,
      "y" : 250
    },
    "minX" : 65,
    "maxX" : 250,
    "minY" : 154,
    "maxY" : 297,
    "prop" : {
      "x" : 65,
      "y" : 204,
      "width" : 132,
      "height" : 93
    },
    "textPosition" : {
      "x" : 67,
      "y" : 205
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "connectors" : [ {
      "edgeId" : 956,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 188,
          "y" : 201
        },
        "to" : {
          "x" : 250,
          "y" : 154
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 953,
    "reactomeId" : 1113578,
    "displayName" : "Homologues of Eukaryotic peptide chain release factor subunit 1",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 143,
      "y" : 73
    },
    "minX" : 85,
    "maxX" : 250,
    "minY" : 41,
    "maxY" : 154,
    "prop" : {
      "x" : 85,
      "y" : 41,
      "width" : 117,
      "height" : 64
    },
    "textPosition" : {
      "x" : 85,
      "y" : 41
    },
    "connectors" : [ {
      "edgeId" : 956,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 185,
          "y" : 111
        },
        "to" : {
          "x" : 250,
          "y" : 154
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 954,
    "reactomeId" : 1115123,
    "displayName" : "GTP bound eRF3",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 119,
      "y" : 153
    },
    "minX" : 61,
    "maxX" : 250,
    "minY" : 117,
    "maxY" : 189,
    "prop" : {
      "x" : 61,
      "y" : 117,
      "width" : 116,
      "height" : 72
    },
    "textPosition" : {
      "x" : 62,
      "y" : 125
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "connectors" : [ {
      "edgeId" : 956,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 180,
          "y" : 153
        },
        "to" : {
          "x" : 250,
          "y" : 154
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 957,
    "reactomeId" : 141681,
    "displayName" : "polypeptide",
    "schemaClass" : "OtherEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 570,
      "y" : 445
    },
    "minX" : 509,
    "maxX" : 632,
    "minY" : 390,
    "maxY" : 456,
    "prop" : {
      "x" : 509,
      "y" : 434,
      "width" : 123,
      "height" : 22
    },
    "textPosition" : {
      "x" : 536,
      "y" : 434
    },
    "connectors" : [ {
      "edgeId" : 962,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 570,
          "y" : 431
        },
        "to" : {
          "x" : 570,
          "y" : 390
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 566,
          "y" : 424
        },
        "b" : {
          "x" : 570,
          "y" : 431
        },
        "c" : {
          "x" : 574,
          "y" : 424
        },
        "type" : "ARROW"
      }
    } ]
  }, {
    "id" : 958,
    "reactomeId" : 29372,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 581,
      "y" : 95
    },
    "minX" : 542,
    "maxX" : 604,
    "minY" : 79,
    "maxY" : 157,
    "prop" : {
      "x" : 560,
      "y" : 80,
      "width" : 43,
      "height" : 31
    },
    "textPosition" : {
      "x" : 572,
      "y" : 84
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 598,
          "y" : 85
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true
      }
    },
    "connectors" : [ {
      "edgeId" : 955,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 571,
          "y" : 114
        },
        "to" : {
          "x" : 542,
          "y" : 157
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 570,
          "y" : 122
        },
        "b" : {
          "x" : 571,
          "y" : 114
        },
        "c" : {
          "x" : 564,
          "y" : 118
        },
        "type" : "ARROW"
      }
    } ]
  }, {
    "id" : 959,
    "reactomeId" : 1115186,
    "displayName" : "eRF3-GDP:eRF1:80S Ribosome:mRNA:peptidyl-tRNA Complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 571,
      "y" : 257
    },
    "minX" : 508,
    "maxX" : 635,
    "minY" : 157,
    "maxY" : 310,
    "prop" : {
      "x" : 508,
      "y" : 204,
      "width" : 127,
      "height" : 106
    },
    "textPosition" : {
      "x" : 511,
      "y" : 218
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "connectors" : [ {
      "edgeId" : 962,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 955,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 555,
          "y" : 201
        },
        "to" : {
          "x" : 542,
          "y" : 157
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 549,
          "y" : 195
        },
        "b" : {
          "x" : 555,
          "y" : 201
        },
        "c" : {
          "x" : 557,
          "y" : 193
        },
        "type" : "ARROW"
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 962,
    "reactomeId" : 1113130,
    "displayName" : "Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 570,
      "y" : 350
    },
    "minX" : 565,
    "maxX" : 575,
    "minY" : 313,
    "maxY" : 390,
    "reactionType" : "Dissociation",
    "segments" : [ {
      "from" : {
        "x" : 570,
        "y" : 313
      },
      "to" : {
        "x" : 570,
        "y" : 350
      }
    }, {
      "from" : {
        "x" : 570,
        "y" : 350
      },
      "to" : {
        "x" : 570,
        "y" : 390
      }
    } ],
    "reactionShape" : {
      "c" : {
        "x" : 570,
        "y" : 350
      },
      "r" : 5,
      "r1" : 3,
      "type" : "DOUBLE_CIRCLE",
      "empty" : true
    },
    "inputs" : [ {
      "id" : 959
    } ],
    "outputs" : [ {
      "id" : 957,
      "points" : [ {
        "x" : 570,
        "y" : 431
      } ]
    }, {
      "id" : 961,
      "points" : [ {
        "x" : 480,
        "y" : 399
      } ]
    } ]
  }, {
    "id" : 955,
    "reactomeId" : 1113127,
    "displayName" : "GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 505,
      "y" : 157
    },
    "minX" : 464,
    "maxX" : 542,
    "minY" : 151,
    "maxY" : 163,
    "segments" : [ {
      "from" : {
        "x" : 464,
        "y" : 156
      },
      "to" : {
        "x" : 505,
        "y" : 157
      }
    }, {
      "from" : {
        "x" : 505,
        "y" : 157
      },
      "to" : {
        "x" : 542,
        "y" : 157
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 499,
        "y" : 151
      },
      "b" : {
        "x" : 511,
        "y" : 163
      },
      "type" : "BOX",
      "empty" : true
    },
    "inputs" : [ {
      "id" : 960
    } ],
    "outputs" : [ {
      "id" : 959,
      "points" : [ {
        "x" : 555,
        "y" : 201
      } ]
    }, {
      "id" : 958,
      "points" : [ {
        "x" : 571,
        "y" : 114
      } ]
    } ]
  }, {
    "id" : 956,
    "reactomeId" : 1113163,
    "displayName" : "GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 291,
      "y" : 154
    },
    "minX" : 250,
    "maxX" : 331,
    "minY" : 149,
    "maxY" : 159,
    "reactionType" : "Association",
    "segments" : [ {
      "from" : {
        "x" : 250,
        "y" : 154
      },
      "to" : {
        "x" : 291,
        "y" : 154
      }
    }, {
      "from" : {
        "x" : 291,
        "y" : 154
      },
      "to" : {
        "x" : 331,
        "y" : 154
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 324,
        "y" : 158
      },
      "b" : {
        "x" : 331,
        "y" : 154
      },
      "c" : {
        "x" : 324,
        "y" : 150
      },
      "type" : "ARROW"
    },
    "reactionShape" : {
      "c" : {
        "x" : 291,
        "y" : 154
      },
      "r" : 5,
      "type" : "CIRCLE"
    },
    "inputs" : [ {
      "id" : 953,
      "points" : [ {
        "x" : 185,
        "y" : 111
      } ]
    }, {
      "id" : 952,
      "points" : [ {
        "x" : 188,
        "y" : 201
      } ]
    }, {
      "id" : 954,
      "points" : [ {
        "x" : 180,
        "y" : 153
      } ]
    } ],
    "outputs" : [ {
      "id" : 960
    } ]
  } ],
  "compartments" : [ {
    "id" : 976,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 349,
      "y" : 252
    },
    "minX" : 4,
    "maxX" : 694,
    "minY" : 8,
    "maxY" : 497,
    "prop" : {
      "x" : 4,
      "y" : 8,
      "width" : 690,
      "height" : 489
    },
    "textPosition" : {
      "x" : 33,
      "y" : 450
    },
    "insets" : {
      "x" : 14,
      "y" : 18,
      "width" : 669,
      "height" : 468
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 952, 953, 954, 955, 956, 958, 959, 960, 961, 962, 957 ]
  } ],
  "notes" : [ ],
  "links" : [ ],
  "shadows" : [ ],
  "minX" : 4,
  "maxX" : 694,
  "minY" : 8,
  "maxY" : 497,
  "disease" : false
}