{ "dbId" : 1119439, "stableId" : "R-OSA-1119439", "displayName" : "Diagram of cholesterol biosynthesis III (via desmosterol)", "nodes" : [ { "id" : 128, "reactomeId" : 1130519, "displayName" : "4alpha-carboxy-5alpha-cholesta-8,24-dien-3beta-ol", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 182, "y" : 2642 }, "minX" : 120, "maxX" : 246, "minY" : 2562, "maxY" : 2695, "prop" : { "x" : 120, "y" : 2613, "width" : 125, "height" : 58 }, "textPosition" : { "x" : 120, "y" : 2617 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 240, "y" : 2618 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 130, "type" : "INPUT", "segments" : [ { "from" : { "x" : 182, "y" : 2674 }, "to" : { "x" : 182, "y" : 2695 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 127, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 181, "y" : 2610 }, "to" : { "x" : 180, "y" : 2562 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 177, "y" : 2603 }, "b" : { "x" : 181, "y" : 2610 }, "c" : { "x" : 185, "y" : 2603 }, "type" : "ARROW" } } ] }, { "id" : 386, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 87, "y" : 2230 }, "minX" : 67, "maxX" : 180, "minY" : 2198, "maxY" : 2245, "prop" : { "x" : 67, "y" : 2215, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 71, "y" : 2219 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 102, "y" : 2220 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 120, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 110, "y" : 2223 }, "to" : { "x" : 180, "y" : 2198 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 115, "y" : 2217 }, "b" : { "x" : 110, "y" : 2223 }, "c" : { "x" : 118, "y" : 2224 }, "type" : "ARROW" } } ], "trivial" : true }, { "id" : 131, "reactomeId" : 1131590, "displayName" : "5alpha-cholesta-8,24-dien-3-one", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 182, "y" : 2793 }, "minX" : 125, "maxX" : 241, "minY" : 2735, "maxY" : 2833, "prop" : { "x" : 125, "y" : 2771, "width" : 115, "height" : 44 }, "textPosition" : { "x" : 133, "y" : 2775 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 235, "y" : 2776 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 130, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 182, "y" : 2768 }, "to" : { "x" : 184, "y" : 2735 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 178, "y" : 2761 }, "b" : { "x" : 182, "y" : 2768 }, "c" : { "x" : 186, "y" : 2761 }, "type" : "ARROW" } }, { "edgeId" : 132, "type" : "INPUT", "segments" : [ { "from" : { "x" : 182, "y" : 2818 }, "to" : { "x" : 182, "y" : 2833 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 388, "reactomeId" : 428206, "displayName" : "NAD(P)H", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 87, "y" : 2126 }, "minX" : 60, "maxX" : 180, "minY" : 2115, "maxY" : 2150, "prop" : { "x" : 60, "y" : 2115, "width" : 55, "height" : 22 }, "textPosition" : { "x" : 60, "y" : 2115 }, "connectors" : [ { "edgeId" : 120, "type" : "INPUT", "segments" : [ { "from" : { "x" : 121, "y" : 2133 }, "to" : { "x" : 180, "y" : 2150 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 133, "reactomeId" : 1132234, "displayName" : "ZSOL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 182, "y" : 2896 }, "minX" : 160, "maxX" : 206, "minY" : 2862, "maxY" : 2911, "prop" : { "x" : 160, "y" : 2881, "width" : 45, "height" : 30 }, "textPosition" : { "x" : 163, "y" : 2885 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 200, "y" : 2886 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 132, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 182, "y" : 2878 }, "to" : { "x" : 182, "y" : 2862 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 178, "y" : 2871 }, "b" : { "x" : 182, "y" : 2878 }, "c" : { "x" : 186, "y" : 2871 }, "type" : "ARROW" } }, { "edgeId" : 134, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 6, "reactomeId" : 1121754, "displayName" : "Squalene synthase", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 323, "y" : 106 }, "minX" : 190, "maxX" : 380, "minY" : 95, "maxY" : 117, "prop" : { "x" : 266, "y" : 95, "width" : 114, "height" : 22 }, "textPosition" : { "x" : 267, "y" : 95 }, "connectors" : [ { "edgeId" : 2, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 260, "y" : 105 }, "to" : { "x" : 198, "y" : 105 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 194, "y" : 105 }, "r" : 4, "type" : "CIRCLE", "empty" : true } } ] }, { "id" : 262, "reactomeId" : 29368, "displayName" : "O2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 87, "y" : 2160 }, "minX" : 71, "maxX" : 180, "minY" : 2144, "maxY" : 2175, "prop" : { "x" : 71, "y" : 2145, "width" : 32, "height" : 30 }, "textPosition" : { "x" : 75, "y" : 2149 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 98, "y" : 2150 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 120, "type" : "INPUT", "segments" : [ { "from" : { "x" : 106, "y" : 2158 }, "to" : { "x" : 180, "y" : 2150 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 390, "reactomeId" : 428218, "displayName" : "NAD(P)+", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 87, "y" : 2193 }, "minX" : 59, "maxX" : 180, "minY" : 2182, "maxY" : 2204, "prop" : { "x" : 59, "y" : 2182, "width" : 57, "height" : 22 }, "textPosition" : { "x" : 60, "y" : 2182 }, "connectors" : [ { "edgeId" : 120, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 122, "y" : 2194 }, "to" : { "x" : 180, "y" : 2198 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 129, "y" : 2190 }, "b" : { "x" : 122, "y" : 2194 }, "c" : { "x" : 129, "y" : 2198 }, "type" : "ARROW" } } ] }, { "id" : 135, "reactomeId" : 1132038, "displayName" : "5alpha-cholesta-7,24-dien-3beta-ol", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 182, "y" : 2988 }, "minX" : 120, "maxX" : 246, "minY" : 2965, "maxY" : 3048, "prop" : { "x" : 120, "y" : 2966, "width" : 125, "height" : 44 }, "textPosition" : { "x" : 120, "y" : 2970 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 240, "y" : 2971 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 134, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 137, "type" : "INPUT", "segments" : [ { "from" : { "x" : 181, "y" : 3013 }, "to" : { "x" : 181, "y" : 3048 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 136, "reactomeId" : 1123211, "displayName" : "3-beta-hydroxysteroid-Delta-isomerase (LOC_OS01G01369.1)", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 323, "y" : 2933 }, "minX" : 190, "maxX" : 392, "minY" : 2895, "maxY" : 2965, "prop" : { "x" : 260, "y" : 2901, "width" : 126, "height" : 64 }, "textPosition" : { "x" : 261, "y" : 2894 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 386, "y" : 2901 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 134, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 257, "y" : 2932 }, "to" : { "x" : 198, "y" : 2931 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 194, "y" : 2931 }, "r" : 4, "type" : "CIRCLE", "empty" : true } } ] }, { "id" : 392, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 78, "y" : 1573 }, "minX" : 58, "maxX" : 182, "minY" : 1542, "maxY" : 1588, "prop" : { "x" : 58, "y" : 1558, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 62, "y" : 1562 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 93, "y" : 1563 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 70, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 101, "y" : 1567 }, "to" : { "x" : 182, "y" : 1542 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 135, "y" : 1548 }, "b" : { "x" : 147, "y" : 1560 }, "type" : "BOX", "empty" : true } }, "endShape" : { "a" : { "x" : 106, "y" : 1561 }, "b" : { "x" : 101, "y" : 1567 }, "c" : { "x" : 109, "y" : 1569 }, "type" : "ARROW" } } ], "trivial" : true }, { "id" : 139, "reactomeId" : 1131584, "displayName" : "7-dehydrodesmosterol", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 182, "y" : 3176 }, "minX" : 115, "maxX" : 250, "minY" : 3110, "maxY" : 3222, "prop" : { "x" : 115, "y" : 3154, "width" : 134, "height" : 44 }, "textPosition" : { "x" : 116, "y" : 3165 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 244, "y" : 3159 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 137, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 182, "y" : 3151 }, "to" : { "x" : 183, "y" : 3110 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 178, "y" : 3144 }, "b" : { "x" : 182, "y" : 3151 }, "c" : { "x" : 186, "y" : 3144 }, "type" : "ARROW" } }, { "edgeId" : 140, "type" : "INPUT", "segments" : [ { "from" : { "x" : 180, "y" : 3201 }, "to" : { "x" : 178, "y" : 3222 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 141, "reactomeId" : 1131768, "displayName" : "DESMO", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 178, "y" : 3294 }, "minX" : 150, "maxX" : 208, "minY" : 3253, "maxY" : 3326, "prop" : { "x" : 150, "y" : 3279, "width" : 57, "height" : 30 }, "textPosition" : { "x" : 154, "y" : 3283 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 202, "y" : 3284 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 140, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 178, "y" : 3276 }, "to" : { "x" : 178, "y" : 3253 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 174, "y" : 3269 }, "b" : { "x" : 178, "y" : 3276 }, "c" : { "x" : 182, "y" : 3269 }, "type" : "ARROW" } }, { "edgeId" : 142, "type" : "INPUT", "segments" : [ { "from" : { "x" : 178, "y" : 3312 }, "to" : { "x" : 178, "y" : 3326 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 398, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 75, "y" : 2425 }, "minX" : 55, "maxX" : 181, "minY" : 2391, "maxY" : 2440, "prop" : { "x" : 55, "y" : 2410, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 59, "y" : 2414 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 90, "y" : 2415 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 124, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 98, "y" : 2418 }, "to" : { "x" : 181, "y" : 2391 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 133, "y" : 2398 }, "b" : { "x" : 145, "y" : 2410 }, "type" : "BOX", "empty" : true } }, "endShape" : { "a" : { "x" : 103, "y" : 2412 }, "b" : { "x" : 98, "y" : 2418 }, "c" : { "x" : 106, "y" : 2420 }, "type" : "ARROW" } } ], "trivial" : true }, { "id" : 270, "reactomeId" : 29368, "displayName" : "O2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 75, "y" : 2345 }, "minX" : 59, "maxX" : 180, "minY" : 2329, "maxY" : 2360, "prop" : { "x" : 59, "y" : 2330, "width" : 32, "height" : 30 }, "textPosition" : { "x" : 63, "y" : 2334 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 86, "y" : 2335 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 124, "type" : "INPUT", "segments" : [ { "from" : { "x" : 94, "y" : 2344 }, "to" : { "x" : 180, "y" : 2339 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 400, "reactomeId" : 428206, "displayName" : "NAD(P)H", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 75, "y" : 2307 }, "minX" : 48, "maxX" : 180, "minY" : 2296, "maxY" : 2339, "prop" : { "x" : 48, "y" : 2296, "width" : 55, "height" : 22 }, "textPosition" : { "x" : 48, "y" : 2296 }, "connectors" : [ { "edgeId" : 124, "type" : "INPUT", "segments" : [ { "from" : { "x" : 109, "y" : 2315 }, "to" : { "x" : 180, "y" : 2339 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 402, "reactomeId" : 428218, "displayName" : "NAD(P)+", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 75, "y" : 2385 }, "minX" : 47, "maxX" : 181, "minY" : 2374, "maxY" : 2396, "prop" : { "x" : 47, "y" : 2374, "width" : 57, "height" : 22 }, "textPosition" : { "x" : 48, "y" : 2374 }, "connectors" : [ { "edgeId" : 124, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 110, "y" : 2386 }, "to" : { "x" : 181, "y" : 2391 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 117, "y" : 2382 }, "b" : { "x" : 110, "y" : 2386 }, "c" : { "x" : 117, "y" : 2390 }, "type" : "ARROW" } } ] }, { "id" : 277, "reactomeId" : 29368, "displayName" : "O2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 75, "y" : 2527 }, "minX" : 59, "maxX" : 181, "minY" : 2511, "maxY" : 2542, "prop" : { "x" : 59, "y" : 2512, "width" : 32, "height" : 30 }, "textPosition" : { "x" : 63, "y" : 2516 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 86, "y" : 2517 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 127, "type" : "INPUT", "segments" : [ { "from" : { "x" : 94, "y" : 2528 }, "to" : { "x" : 181, "y" : 2535 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 21, "reactomeId" : 1131375, "displayName" : "4,4-dimethyl-14alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 182, "y" : 701 }, "minX" : 120, "maxX" : 246, "minY" : 625, "maxY" : 775, "prop" : { "x" : 120, "y" : 658, "width" : 125, "height" : 86 }, "textPosition" : { "x" : 120, "y" : 669 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 240, "y" : 663 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 20, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 182, "y" : 655 }, "to" : { "x" : 182, "y" : 625 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 178, "y" : 648 }, "b" : { "x" : 182, "y" : 655 }, "c" : { "x" : 186, "y" : 648 }, "type" : "ARROW" } }, { "edgeId" : 23, "type" : "INPUT", "segments" : [ { "from" : { "x" : 182, "y" : 747 }, "to" : { "x" : 182, "y" : 775 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 406, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 75, "y" : 2602 }, "minX" : 55, "maxX" : 180, "minY" : 2562, "maxY" : 2617, "prop" : { "x" : 55, "y" : 2587, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 59, "y" : 2591 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 90, "y" : 2592 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 127, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 98, "y" : 2594 }, "to" : { "x" : 180, "y" : 2562 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 103, "y" : 2588 }, "b" : { "x" : 98, "y" : 2594 }, "c" : { "x" : 106, "y" : 2595 }, "type" : "ARROW" } } ], "trivial" : true }, { "id" : 278, "reactomeId" : 113528, "displayName" : "CO2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 75, "y" : 2765 }, "minX" : 55, "maxX" : 184, "minY" : 2735, "maxY" : 2780, "prop" : { "x" : 55, "y" : 2750, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 59, "y" : 2754 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 90, "y" : 2755 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 130, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 98, "y" : 2759 }, "to" : { "x" : 184, "y" : 2735 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 104, "y" : 2753 }, "b" : { "x" : 98, "y" : 2759 }, "c" : { "x" : 106, "y" : 2761 }, "type" : "ARROW" } } ], "trivial" : true }, { "id" : 408, "reactomeId" : 428206, "displayName" : "NAD(P)H", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 75, "y" : 2493 }, "minX" : 48, "maxX" : 181, "minY" : 2482, "maxY" : 2535, "prop" : { "x" : 48, "y" : 2482, "width" : 55, "height" : 22 }, "textPosition" : { "x" : 48, "y" : 2482 }, "connectors" : [ { "edgeId" : 127, "type" : "INPUT", "segments" : [ { "from" : { "x" : 102, "y" : 2510 }, "to" : { "x" : 181, "y" : 2535 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 24, "reactomeId" : 1131178, "displayName" : "4,4-dimethyl-14alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 182, "y" : 882 }, "minX" : 120, "maxX" : 246, "minY" : 805, "maxY" : 952, "prop" : { "x" : 120, "y" : 846, "width" : 125, "height" : 72 }, "textPosition" : { "x" : 120, "y" : 850 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 240, "y" : 851 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 23, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 182, "y" : 843 }, "to" : { "x" : 182, "y" : 805 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 178, "y" : 836 }, "b" : { "x" : 182, "y" : 843 }, "c" : { "x" : 186, "y" : 836 }, "type" : "ARROW" } }, { "edgeId" : 26, "type" : "INPUT", "segments" : [ { "from" : { "x" : 182, "y" : 921 }, "to" : { "x" : 182, "y" : 952 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 410, "reactomeId" : 428218, "displayName" : "NAD(P)+", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 75, "y" : 2562 }, "minX" : 47, "maxX" : 180, "minY" : 2551, "maxY" : 2573, "prop" : { "x" : 47, "y" : 2551, "width" : 57, "height" : 22 }, "textPosition" : { "x" : 48, "y" : 2551 }, "connectors" : [ { "edgeId" : 127, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 110, "y" : 2562 }, "to" : { "x" : 180, "y" : 2562 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 117, "y" : 2558 }, "b" : { "x" : 110, "y" : 2562 }, "c" : { "x" : 117, "y" : 2566 }, "type" : "ARROW" } } ] }, { "id" : 27, "reactomeId" : 1131904, "displayName" : "4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 182, "y" : 1082 }, "minX" : 127, "maxX" : 238, "minY" : 1018, "maxY" : 1133, "prop" : { "x" : 127, "y" : 1046, "width" : 110, "height" : 72 }, "textPosition" : { "x" : 136, "y" : 1050 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 232, "y" : 1051 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 26, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 182, "y" : 1043 }, "to" : { "x" : 182, "y" : 1018 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 178, "y" : 1036 }, "b" : { "x" : 182, "y" : 1043 }, "c" : { "x" : 186, "y" : 1036 }, "type" : "ARROW" } }, { "edgeId" : 30, "type" : "INPUT", "segments" : [ { "from" : { "x" : 182, "y" : 1121 }, "to" : { "x" : 182, "y" : 1133 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 284, "reactomeId" : 29364, "displayName" : "NADPH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 75, "y" : 2823 }, "minX" : 47, "maxX" : 182, "minY" : 2807, "maxY" : 2838, "prop" : { "x" : 47, "y" : 2808, "width" : 57, "height" : 30 }, "textPosition" : { "x" : 52, "y" : 2812 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 99, "y" : 2813 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 132, "type" : "INPUT", "segments" : [ { "from" : { "x" : 107, "y" : 2825 }, "to" : { "x" : 182, "y" : 2833 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 285, "reactomeId" : 29366, "displayName" : "NADP+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 75, "y" : 2865 }, "minX" : 46, "maxX" : 182, "minY" : 2849, "maxY" : 2880, "prop" : { "x" : 46, "y" : 2850, "width" : 58, "height" : 30 }, "textPosition" : { "x" : 51, "y" : 2854 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 99, "y" : 2855 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 132, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 107, "y" : 2864 }, "to" : { "x" : 182, "y" : 2862 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 114, "y" : 2860 }, "b" : { "x" : 107, "y" : 2864 }, "c" : { "x" : 114, "y" : 2868 }, "type" : "ARROW" } } ] }, { "id" : 414, "reactomeId" : 428206, "displayName" : "NAD(P)H", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 75, "y" : 2725 }, "minX" : 48, "maxX" : 184, "minY" : 2714, "maxY" : 2736, "prop" : { "x" : 48, "y" : 2714, "width" : 55, "height" : 22 }, "textPosition" : { "x" : 48, "y" : 2714 }, "connectors" : [ { "edgeId" : 130, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 109, "y" : 2727 }, "to" : { "x" : 184, "y" : 2735 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 116, "y" : 2724 }, "b" : { "x" : 109, "y" : 2727 }, "c" : { "x" : 115, "y" : 2732 }, "type" : "ARROW" } } ] }, { "id" : 31, "reactomeId" : 1130992, "displayName" : "4,4-dimethyl-5alpha-cholesta-8,24-dien-3-beta-ol", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 182, "y" : 1220 }, "minX" : 116, "maxX" : 249, "minY" : 1162, "maxY" : 1295, "prop" : { "x" : 116, "y" : 1191, "width" : 132, "height" : 58 }, "textPosition" : { "x" : 121, "y" : 1195 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 243, "y" : 1196 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 66, "type" : "INPUT", "segments" : [ { "from" : { "x" : 181, "y" : 1252 }, "to" : { "x" : 181, "y" : 1295 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 30, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 182, "y" : 1188 }, "to" : { "x" : 182, "y" : 1162 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 178, "y" : 1181 }, "b" : { "x" : 182, "y" : 1188 }, "c" : { "x" : 186, "y" : 1181 }, "type" : "ARROW" } } ] }, { "id" : 416, "reactomeId" : 428218, "displayName" : "NAD(P)+", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 75, "y" : 2684 }, "minX" : 47, "maxX" : 182, "minY" : 2673, "maxY" : 2695, "prop" : { "x" : 47, "y" : 2673, "width" : 57, "height" : 22 }, "textPosition" : { "x" : 48, "y" : 2673 }, "connectors" : [ { "edgeId" : 130, "type" : "INPUT", "segments" : [ { "from" : { "x" : 110, "y" : 2686 }, "to" : { "x" : 182, "y" : 2695 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 419, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 70, "y" : 3129 }, "minX" : 50, "maxX" : 183, "minY" : 3110, "maxY" : 3144, "prop" : { "x" : 50, "y" : 3114, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 54, "y" : 3118 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 85, "y" : 3119 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 137, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 93, "y" : 3125 }, "to" : { "x" : 183, "y" : 3110 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 132, "y" : 3111 }, "b" : { "x" : 144, "y" : 3123 }, "type" : "BOX", "empty" : true } }, "endShape" : { "a" : { "x" : 99, "y" : 3120 }, "b" : { "x" : 93, "y" : 3125 }, "c" : { "x" : 100, "y" : 3128 }, "type" : "ARROW" } } ], "trivial" : true }, { "id" : 421, "reactomeId" : 428206, "displayName" : "NAD(P)H", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 70, "y" : 3012 }, "minX" : 43, "maxX" : 181, "minY" : 3001, "maxY" : 3048, "prop" : { "x" : 43, "y" : 3001, "width" : 55, "height" : 22 }, "textPosition" : { "x" : 43, "y" : 3001 }, "connectors" : [ { "edgeId" : 137, "type" : "INPUT", "segments" : [ { "from" : { "x" : 104, "y" : 3020 }, "to" : { "x" : 181, "y" : 3048 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 293, "reactomeId" : 29368, "displayName" : "O2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 70, "y" : 3049 }, "minX" : 54, "maxX" : 181, "minY" : 3033, "maxY" : 3064, "prop" : { "x" : 54, "y" : 3034, "width" : 32, "height" : 30 }, "textPosition" : { "x" : 58, "y" : 3038 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 81, "y" : 3039 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 137, "type" : "INPUT", "segments" : [ { "from" : { "x" : 89, "y" : 3048 }, "to" : { "x" : 181, "y" : 3048 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 423, "reactomeId" : 428218, "displayName" : "NAD(P)+", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 70, "y" : 3087 }, "minX" : 42, "maxX" : 183, "minY" : 3076, "maxY" : 3110, "prop" : { "x" : 42, "y" : 3076, "width" : 57, "height" : 22 }, "textPosition" : { "x" : 43, "y" : 3076 }, "connectors" : [ { "edgeId" : 137, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 105, "y" : 3092 }, "to" : { "x" : 183, "y" : 3110 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 113, "y" : 3090 }, "b" : { "x" : 105, "y" : 3092 }, "c" : { "x" : 111, "y" : 3097 }, "type" : "ARROW" } } ] }, { "id" : 424, "reactomeId" : 191385, "displayName" : "FAPP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 182, "y" : 55 }, "minX" : 160, "maxX" : 206, "minY" : 39, "maxY" : 70, "prop" : { "x" : 160, "y" : 40, "width" : 45, "height" : 30 }, "textPosition" : { "x" : 164, "y" : 44 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 200, "y" : 45 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 2, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 296, "reactomeId" : 29364, "displayName" : "NADPH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 70, "y" : 3211 }, "minX" : 42, "maxX" : 178, "minY" : 3195, "maxY" : 3226, "prop" : { "x" : 42, "y" : 3196, "width" : 57, "height" : 30 }, "textPosition" : { "x" : 47, "y" : 3200 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 94, "y" : 3201 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 140, "type" : "INPUT", "segments" : [ { "from" : { "x" : 102, "y" : 3213 }, "to" : { "x" : 178, "y" : 3222 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 425, "reactomeId" : 191265, "displayName" : "PSQPP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 182, "y" : 171 }, "minX" : 156, "maxX" : 209, "minY" : 121, "maxY" : 217, "prop" : { "x" : 156, "y" : 156, "width" : 52, "height" : 30 }, "textPosition" : { "x" : 159, "y" : 160 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 203, "y" : 161 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 2, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 182, "y" : 153 }, "to" : { "x" : 182, "y" : 121 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 178, "y" : 146 }, "b" : { "x" : 182, "y" : 153 }, "c" : { "x" : 186, "y" : 146 }, "type" : "ARROW" } }, { "edgeId" : 7, "type" : "INPUT", "segments" : [ { "from" : { "x" : 182, "y" : 189 }, "to" : { "x" : 182, "y" : 217 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 297, "reactomeId" : 29366, "displayName" : "NADP+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 70, "y" : 3251 }, "minX" : 41, "maxX" : 178, "minY" : 3235, "maxY" : 3266, "prop" : { "x" : 41, "y" : 3236, "width" : 58, "height" : 30 }, "textPosition" : { "x" : 46, "y" : 3240 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 94, "y" : 3241 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 140, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 102, "y" : 3251 }, "to" : { "x" : 178, "y" : 3253 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 109, "y" : 3247 }, "b" : { "x" : 102, "y" : 3251 }, "c" : { "x" : 109, "y" : 3255 }, "type" : "ARROW" } } ] }, { "id" : 426, "reactomeId" : 191309, "displayName" : "SQOX", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 182, "y" : 445 }, "minX" : 159, "maxX" : 207, "minY" : 401, "maxY" : 460, "prop" : { "x" : 159, "y" : 430, "width" : 47, "height" : 30 }, "textPosition" : { "x" : 162, "y" : 434 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 201, "y" : 435 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 12, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 182, "y" : 427 }, "to" : { "x" : 183, "y" : 401 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 178, "y" : 420 }, "b" : { "x" : 182, "y" : 427 }, "c" : { "x" : 186, "y" : 420 }, "type" : "ARROW" } }, { "edgeId" : 18, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 298, "reactomeId" : 176478, "displayName" : "CHOL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 178, "y" : 3390 }, "minX" : 154, "maxX" : 203, "minY" : 3357, "maxY" : 3405, "prop" : { "x" : 154, "y" : 3375, "width" : 48, "height" : 30 }, "textPosition" : { "x" : 158, "y" : 3379 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 197, "y" : 3380 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 142, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 178, "y" : 3372 }, "to" : { "x" : 178, "y" : 3357 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 174, "y" : 3365 }, "b" : { "x" : 178, "y" : 3372 }, "c" : { "x" : 182, "y" : 3365 }, "type" : "ARROW" } } ] }, { "id" : 301, "reactomeId" : 29364, "displayName" : "NADPH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 70, "y" : 3312 }, "minX" : 42, "maxX" : 178, "minY" : 3296, "maxY" : 3327, "prop" : { "x" : 42, "y" : 3297, "width" : 57, "height" : 30 }, "textPosition" : { "x" : 47, "y" : 3301 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 94, "y" : 3302 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 142, "type" : "INPUT", "segments" : [ { "from" : { "x" : 102, "y" : 3315 }, "to" : { "x" : 178, "y" : 3326 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 302, "reactomeId" : 29366, "displayName" : "NADP+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 70, "y" : 3356 }, "minX" : 41, "maxX" : 178, "minY" : 3340, "maxY" : 3371, "prop" : { "x" : 41, "y" : 3341, "width" : 58, "height" : 30 }, "textPosition" : { "x" : 46, "y" : 3345 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 94, "y" : 3346 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 142, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 102, "y" : 3356 }, "to" : { "x" : 178, "y" : 3357 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 109, "y" : 3352 }, "b" : { "x" : 102, "y" : 3356 }, "c" : { "x" : 109, "y" : 3360 }, "type" : "ARROW" } } ] }, { "id" : 174, "reactomeId" : 111294, "displayName" : "PPi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 129 }, "minX" : 63, "maxX" : 182, "minY" : 113, "maxY" : 144, "prop" : { "x" : 63, "y" : 114, "width" : 33, "height" : 30 }, "textPosition" : { "x" : 67, "y" : 118 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 91, "y" : 119 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 2, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 99, "y" : 127 }, "to" : { "x" : 182, "y" : 121 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 106, "y" : 123 }, "b" : { "x" : 99, "y" : 127 }, "c" : { "x" : 106, "y" : 130 }, "type" : "ARROW" } } ] }, { "id" : 176, "reactomeId" : 1121754, "displayName" : "Squalene synthase", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 323, "y" : 235 }, "minX" : 190, "maxX" : 380, "minY" : 224, "maxY" : 246, "prop" : { "x" : 266, "y" : 224, "width" : 114, "height" : 22 }, "textPosition" : { "x" : 267, "y" : 224 }, "connectors" : [ { "edgeId" : 7, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 260, "y" : 234 }, "to" : { "x" : 198, "y" : 233 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 194, "y" : 233 }, "r" : 4, "type" : "CIRCLE", "empty" : true } } ] }, { "id" : 177, "reactomeId" : 111294, "displayName" : "PPi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 289 }, "minX" : 63, "maxX" : 181, "minY" : 257, "maxY" : 304, "prop" : { "x" : 63, "y" : 274, "width" : 33, "height" : 30 }, "textPosition" : { "x" : 67, "y" : 278 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 91, "y" : 279 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 7, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 99, "y" : 283 }, "to" : { "x" : 181, "y" : 257 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 104, "y" : 277 }, "b" : { "x" : 99, "y" : 283 }, "c" : { "x" : 107, "y" : 285 }, "type" : "ARROW" } } ] }, { "id" : 178, "reactomeId" : 29368, "displayName" : "O2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 326 }, "minX" : 63, "maxX" : 182, "minY" : 310, "maxY" : 354, "prop" : { "x" : 63, "y" : 311, "width" : 32, "height" : 30 }, "textPosition" : { "x" : 67, "y" : 315 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 90, "y" : 316 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 12, "type" : "INPUT", "segments" : [ { "from" : { "x" : 98, "y" : 330 }, "to" : { "x" : 182, "y" : 354 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 179, "reactomeId" : 29364, "displayName" : "NADPH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 357 }, "minX" : 51, "maxX" : 182, "minY" : 341, "maxY" : 372, "prop" : { "x" : 51, "y" : 342, "width" : 57, "height" : 30 }, "textPosition" : { "x" : 56, "y" : 346 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 103, "y" : 347 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 12, "type" : "INPUT", "segments" : [ { "from" : { "x" : 111, "y" : 356 }, "to" : { "x" : 182, "y" : 354 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 180, "reactomeId" : 29366, "displayName" : "NADP+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 389 }, "minX" : 50, "maxX" : 183, "minY" : 373, "maxY" : 404, "prop" : { "x" : 50, "y" : 374, "width" : 58, "height" : 30 }, "textPosition" : { "x" : 55, "y" : 378 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 103, "y" : 379 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 12, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 111, "y" : 392 }, "to" : { "x" : 183, "y" : 401 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 118, "y" : 389 }, "b" : { "x" : 111, "y" : 392 }, "c" : { "x" : 117, "y" : 397 }, "type" : "ARROW" } } ] }, { "id" : 183, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 424 }, "minX" : 59, "maxX" : 183, "minY" : 401, "maxY" : 439, "prop" : { "x" : 59, "y" : 409, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 63, "y" : 413 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 94, "y" : 414 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 12, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 102, "y" : 419 }, "to" : { "x" : 183, "y" : 401 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 108, "y" : 414 }, "b" : { "x" : 102, "y" : 419 }, "c" : { "x" : 110, "y" : 421 }, "type" : "ARROW" } } ], "trivial" : true }, { "id" : 184, "reactomeId" : 191269, "displayName" : "SQNE", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 182, "y" : 300 }, "minX" : 159, "maxX" : 207, "minY" : 257, "maxY" : 354, "prop" : { "x" : 159, "y" : 285, "width" : 47, "height" : 30 }, "textPosition" : { "x" : 163, "y" : 289 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 201, "y" : 290 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 7, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 181, "y" : 282 }, "to" : { "x" : 181, "y" : 257 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 177, "y" : 275 }, "b" : { "x" : 181, "y" : 282 }, "c" : { "x" : 185, "y" : 275 }, "type" : "ARROW" } }, { "edgeId" : 12, "type" : "INPUT", "segments" : [ { "from" : { "x" : 182, "y" : 318 }, "to" : { "x" : 182, "y" : 354 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 186, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 658 }, "minX" : 59, "maxX" : 182, "minY" : 625, "maxY" : 673, "prop" : { "x" : 59, "y" : 643, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 63, "y" : 647 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 94, "y" : 648 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 20, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 102, "y" : 651 }, "to" : { "x" : 182, "y" : 625 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 107, "y" : 645 }, "b" : { "x" : 102, "y" : 651 }, "c" : { "x" : 110, "y" : 653 }, "type" : "ARROW" } } ], "trivial" : true }, { "id" : 318, "reactomeId" : 191280, "displayName" : "Lanosterol", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 182, "y" : 541 }, "minX" : 144, "maxX" : 222, "minY" : 525, "maxY" : 581, "prop" : { "x" : 144, "y" : 526, "width" : 77, "height" : 30 }, "textPosition" : { "x" : 149, "y" : 530 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 216, "y" : 531 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 18, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 20, "type" : "INPUT", "segments" : [ { "from" : { "x" : 182, "y" : 559 }, "to" : { "x" : 182, "y" : 581 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 190, "reactomeId" : 29368, "displayName" : "O2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 559 }, "minX" : 63, "maxX" : 182, "minY" : 543, "maxY" : 581, "prop" : { "x" : 63, "y" : 544, "width" : 32, "height" : 30 }, "textPosition" : { "x" : 67, "y" : 548 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 90, "y" : 549 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 20, "type" : "INPUT", "segments" : [ { "from" : { "x" : 98, "y" : 562 }, "to" : { "x" : 182, "y" : 581 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 191, "reactomeId" : 29364, "displayName" : "NADPH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 590 }, "minX" : 51, "maxX" : 182, "minY" : 574, "maxY" : 605, "prop" : { "x" : 51, "y" : 575, "width" : 57, "height" : 30 }, "textPosition" : { "x" : 56, "y" : 579 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 103, "y" : 580 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 20, "type" : "INPUT", "segments" : [ { "from" : { "x" : 111, "y" : 587 }, "to" : { "x" : 182, "y" : 581 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 192, "reactomeId" : 29366, "displayName" : "NADP+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 623 }, "minX" : 50, "maxX" : 182, "minY" : 607, "maxY" : 638, "prop" : { "x" : 50, "y" : 608, "width" : 58, "height" : 30 }, "textPosition" : { "x" : 55, "y" : 612 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 103, "y" : 613 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 20, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 111, "y" : 623 }, "to" : { "x" : 182, "y" : 625 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 118, "y" : 619 }, "b" : { "x" : 111, "y" : 623 }, "c" : { "x" : 118, "y" : 627 }, "type" : "ARROW" } } ] }, { "id" : 67, "reactomeId" : 1130831, "displayName" : "4alpha-hydroxymethyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 182, "y" : 1408 }, "minX" : 120, "maxX" : 246, "minY" : 1347, "maxY" : 1484, "prop" : { "x" : 120, "y" : 1365, "width" : 125, "height" : 86 }, "textPosition" : { "x" : 120, "y" : 1369 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 240, "y" : 1370 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 66, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 180, "y" : 1362 }, "to" : { "x" : 180, "y" : 1347 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 176, "y" : 1355 }, "b" : { "x" : 180, "y" : 1362 }, "c" : { "x" : 184, "y" : 1355 }, "type" : "ARROW" } }, { "edgeId" : 70, "type" : "INPUT", "segments" : [ { "from" : { "x" : 182, "y" : 1454 }, "to" : { "x" : 182, "y" : 1484 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 195, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 805 }, "minX" : 59, "maxX" : 182, "minY" : 789, "maxY" : 820, "prop" : { "x" : 59, "y" : 790, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 63, "y" : 794 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 94, "y" : 795 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 23, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 102, "y" : 805 }, "to" : { "x" : 182, "y" : 805 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 136, "y" : 799 }, "b" : { "x" : 148, "y" : 811 }, "type" : "BOX", "empty" : true } }, "endShape" : { "a" : { "x" : 109, "y" : 801 }, "b" : { "x" : 102, "y" : 805 }, "c" : { "x" : 109, "y" : 809 }, "type" : "ARROW" } } ], "trivial" : true }, { "id" : 69, "reactomeId" : 1121733, "displayName" : "Methylsterol monooxygenase", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 320, "y" : 1513 }, "minX" : 189, "maxX" : 373, "minY" : 1323, "maxY" : 1718, "prop" : { "x" : 268, "y" : 1495, "width" : 105, "height" : 36 }, "textPosition" : { "x" : 271, "y" : 1495 }, "connectors" : [ { "edgeId" : 66, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 314, "y" : 1489 }, "to" : { "x" : 264, "y" : 1326 } }, { "from" : { "x" : 264, "y" : 1326 }, "to" : { "x" : 197, "y" : 1327 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 193, "y" : 1327 }, "r" : 4, "type" : "CIRCLE", "empty" : true } }, { "edgeId" : 70, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 262, "y" : 1512 }, "to" : { "x" : 198, "y" : 1512 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 194, "y" : 1512 }, "r" : 4, "type" : "CIRCLE", "empty" : true } }, { "edgeId" : 73, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 315, "y" : 1537 }, "to" : { "x" : 267, "y" : 1714 } }, { "from" : { "x" : 267, "y" : 1714 }, "to" : { "x" : 198, "y" : 1714 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 194, "y" : 1714 }, "r" : 4, "type" : "CIRCLE", "empty" : true } } ] }, { "id" : 199, "reactomeId" : 29368, "displayName" : "O2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 740 }, "minX" : 63, "maxX" : 182, "minY" : 724, "maxY" : 775, "prop" : { "x" : 63, "y" : 725, "width" : 32, "height" : 30 }, "textPosition" : { "x" : 67, "y" : 729 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 90, "y" : 730 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 23, "type" : "INPUT", "segments" : [ { "from" : { "x" : 98, "y" : 745 }, "to" : { "x" : 182, "y" : 775 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 72, "reactomeId" : 1130530, "displayName" : "4alpha-formyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 182, "y" : 1617 }, "minX" : 120, "maxX" : 246, "minY" : 1542, "maxY" : 1689, "prop" : { "x" : 120, "y" : 1581, "width" : 125, "height" : 72 }, "textPosition" : { "x" : 123, "y" : 1585 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 240, "y" : 1586 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 70, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 182, "y" : 1578 }, "to" : { "x" : 182, "y" : 1542 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 178, "y" : 1571 }, "b" : { "x" : 182, "y" : 1578 }, "c" : { "x" : 186, "y" : 1571 }, "type" : "ARROW" } }, { "edgeId" : 73, "type" : "INPUT", "segments" : [ { "from" : { "x" : 181, "y" : 1656 }, "to" : { "x" : 181, "y" : 1689 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 200, "reactomeId" : 29364, "displayName" : "NADPH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 772 }, "minX" : 51, "maxX" : 182, "minY" : 756, "maxY" : 787, "prop" : { "x" : 51, "y" : 757, "width" : 57, "height" : 30 }, "textPosition" : { "x" : 56, "y" : 761 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 103, "y" : 762 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 23, "type" : "INPUT", "segments" : [ { "from" : { "x" : 111, "y" : 772 }, "to" : { "x" : 182, "y" : 775 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 201, "reactomeId" : 29366, "displayName" : "NADP+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 840 }, "minX" : 50, "maxX" : 182, "minY" : 805, "maxY" : 855, "prop" : { "x" : 50, "y" : 825, "width" : 58, "height" : 30 }, "textPosition" : { "x" : 55, "y" : 829 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 103, "y" : 830 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 23, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 111, "y" : 830 }, "to" : { "x" : 182, "y" : 805 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 116, "y" : 824 }, "b" : { "x" : 111, "y" : 830 }, "c" : { "x" : 119, "y" : 831 }, "type" : "ARROW" } } ] }, { "id" : 330, "reactomeId" : 428206, "displayName" : "NAD(P)H", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 80, "y" : 208 }, "minX" : 53, "maxX" : 182, "minY" : 197, "maxY" : 219, "prop" : { "x" : 53, "y" : 197, "width" : 55, "height" : 22 }, "textPosition" : { "x" : 53, "y" : 197 }, "connectors" : [ { "edgeId" : 7, "type" : "INPUT", "segments" : [ { "from" : { "x" : 114, "y" : 210 }, "to" : { "x" : 182, "y" : 217 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74, "reactomeId" : 1130851, "displayName" : "4alpha-carboxy-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 182, "y" : 1810 }, "minX" : 120, "maxX" : 246, "minY" : 1740, "maxY" : 1869, "prop" : { "x" : 120, "y" : 1774, "width" : 125, "height" : 72 }, "textPosition" : { "x" : 122, "y" : 1778 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 240, "y" : 1779 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 73, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 181, "y" : 1771 }, "to" : { "x" : 181, "y" : 1740 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 177, "y" : 1764 }, "b" : { "x" : 181, "y" : 1771 }, "c" : { "x" : 185, "y" : 1764 }, "type" : "ARROW" } }, { "edgeId" : 76, "type" : "INPUT", "segments" : [ { "from" : { "x" : 179, "y" : 1849 }, "to" : { "x" : 178, "y" : 1869 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 204, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 1053 }, "minX" : 59, "maxX" : 182, "minY" : 1018, "maxY" : 1068, "prop" : { "x" : 59, "y" : 1038, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 63, "y" : 1042 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 94, "y" : 1043 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 26, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 102, "y" : 1046 }, "to" : { "x" : 182, "y" : 1018 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 107, "y" : 1040 }, "b" : { "x" : 102, "y" : 1046 }, "c" : { "x" : 110, "y" : 1047 }, "type" : "ARROW" } } ], "trivial" : true }, { "id" : 205, "reactomeId" : 29460, "displayName" : "HCOOH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 1018 }, "minX" : 50, "maxX" : 182, "minY" : 1002, "maxY" : 1033, "prop" : { "x" : 50, "y" : 1003, "width" : 58, "height" : 30 }, "textPosition" : { "x" : 54, "y" : 1007 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 103, "y" : 1008 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 26, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 111, "y" : 1018 }, "to" : { "x" : 182, "y" : 1018 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 118, "y" : 1014 }, "b" : { "x" : 111, "y" : 1018 }, "c" : { "x" : 118, "y" : 1022 }, "type" : "ARROW" } } ] }, { "id" : 77, "reactomeId" : 1130659, "displayName" : "4alpha-methyl-5alpha-cholesta-8,24-dien-3-one", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 181, "y" : 1974 }, "minX" : 124, "maxX" : 240, "minY" : 1910, "maxY" : 2026, "prop" : { "x" : 124, "y" : 1945, "width" : 115, "height" : 58 }, "textPosition" : { "x" : 132, "y" : 1949 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 234, "y" : 1950 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 76, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 179, "y" : 1942 }, "to" : { "x" : 178, "y" : 1910 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 175, "y" : 1935 }, "b" : { "x" : 179, "y" : 1942 }, "c" : { "x" : 183, "y" : 1935 }, "type" : "ARROW" } }, { "edgeId" : 79, "type" : "INPUT", "segments" : [ { "from" : { "x" : 180, "y" : 2006 }, "to" : { "x" : 180, "y" : 2026 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 80, "reactomeId" : 1131029, "displayName" : "4-alpha-methyl zymosterol", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 180, "y" : 2097 }, "minX" : 125, "maxX" : 236, "minY" : 2057, "maxY" : 2150, "prop" : { "x" : 125, "y" : 2075, "width" : 110, "height" : 44 }, "textPosition" : { "x" : 134, "y" : 2079 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 230, "y" : 2080 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 79, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 180, "y" : 2072 }, "to" : { "x" : 180, "y" : 2057 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 176, "y" : 2065 }, "b" : { "x" : 180, "y" : 2072 }, "c" : { "x" : 184, "y" : 2065 }, "type" : "ARROW" } }, { "edgeId" : 120, "type" : "INPUT", "segments" : [ { "from" : { "x" : 180, "y" : 2122 }, "to" : { "x" : 180, "y" : 2150 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 209, "reactomeId" : 29368, "displayName" : "O2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 910 }, "minX" : 63, "maxX" : 182, "minY" : 894, "maxY" : 952, "prop" : { "x" : 63, "y" : 895, "width" : 32, "height" : 30 }, "textPosition" : { "x" : 67, "y" : 899 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 90, "y" : 900 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 26, "type" : "INPUT", "segments" : [ { "from" : { "x" : 98, "y" : 916 }, "to" : { "x" : 182, "y" : 952 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 210, "reactomeId" : 29364, "displayName" : "NADPH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 944 }, "minX" : 51, "maxX" : 182, "minY" : 928, "maxY" : 959, "prop" : { "x" : 51, "y" : 929, "width" : 57, "height" : 30 }, "textPosition" : { "x" : 56, "y" : 933 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 103, "y" : 934 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 26, "type" : "INPUT", "segments" : [ { "from" : { "x" : 111, "y" : 946 }, "to" : { "x" : 182, "y" : 952 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 211, "reactomeId" : 29366, "displayName" : "NADP+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 985 }, "minX" : 50, "maxX" : 182, "minY" : 969, "maxY" : 1018, "prop" : { "x" : 50, "y" : 970, "width" : 58, "height" : 30 }, "textPosition" : { "x" : 55, "y" : 974 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 103, "y" : 975 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 26, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 111, "y" : 994 }, "to" : { "x" : 182, "y" : 1018 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 119, "y" : 992 }, "b" : { "x" : 111, "y" : 994 }, "c" : { "x" : 116, "y" : 1000 }, "type" : "ARROW" } } ] }, { "id" : 340, "reactomeId" : 428218, "displayName" : "NAD(P)+", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 80, "y" : 249 }, "minX" : 52, "maxX" : 181, "minY" : 238, "maxY" : 260, "prop" : { "x" : 52, "y" : 238, "width" : 57, "height" : 22 }, "textPosition" : { "x" : 53, "y" : 238 }, "connectors" : [ { "edgeId" : 7, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 115, "y" : 251 }, "to" : { "x" : 181, "y" : 257 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 122, "y" : 248 }, "b" : { "x" : 115, "y" : 251 }, "c" : { "x" : 122, "y" : 256 }, "type" : "ARROW" } } ] }, { "id" : 215, "reactomeId" : 29364, "displayName" : "NADPH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 1126 }, "minX" : 51, "maxX" : 182, "minY" : 1110, "maxY" : 1141, "prop" : { "x" : 51, "y" : 1111, "width" : 57, "height" : 30 }, "textPosition" : { "x" : 56, "y" : 1115 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 103, "y" : 1116 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 30, "type" : "INPUT", "segments" : [ { "from" : { "x" : 111, "y" : 1127 }, "to" : { "x" : 182, "y" : 1133 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 216, "reactomeId" : 29366, "displayName" : "NADP+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 1166 }, "minX" : 50, "maxX" : 182, "minY" : 1150, "maxY" : 1181, "prop" : { "x" : 50, "y" : 1151, "width" : 58, "height" : 30 }, "textPosition" : { "x" : 55, "y" : 1155 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 103, "y" : 1156 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 30, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 111, "y" : 1164 }, "to" : { "x" : 182, "y" : 1162 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 118, "y" : 1160 }, "b" : { "x" : 111, "y" : 1164 }, "c" : { "x" : 118, "y" : 1168 }, "type" : "ARROW" } } ] }, { "id" : 222, "reactomeId" : 1121733, "displayName" : "Methylsterol monooxygenase", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 313, "y" : 2171 }, "minX" : 188, "maxX" : 363, "minY" : 2153, "maxY" : 2189, "prop" : { "x" : 263, "y" : 2153, "width" : 100, "height" : 36 }, "textPosition" : { "x" : 263, "y" : 2153 }, "connectors" : [ { "edgeId" : 120, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 257, "y" : 2171 }, "to" : { "x" : 196, "y" : 2171 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 192, "y" : 2171 }, "r" : 4, "type" : "CIRCLE", "empty" : true } } ] }, { "id" : 224, "reactomeId" : 1121733, "displayName" : "Methylsterol monooxygenase", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 323, "y" : 2552 }, "minX" : 190, "maxX" : 373, "minY" : 2534, "maxY" : 2570, "prop" : { "x" : 273, "y" : 2534, "width" : 100, "height" : 36 }, "textPosition" : { "x" : 273, "y" : 2534 }, "connectors" : [ { "edgeId" : 127, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 267, "y" : 2552 }, "to" : { "x" : 198, "y" : 2552 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 194, "y" : 2552 }, "r" : 4, "type" : "CIRCLE", "empty" : true } } ] }, { "id" : 352, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 1367 }, "minX" : 59, "maxX" : 180, "minY" : 1347, "maxY" : 1382, "prop" : { "x" : 59, "y" : 1352, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 63, "y" : 1356 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 94, "y" : 1357 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 66, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 102, "y" : 1363 }, "to" : { "x" : 180, "y" : 1347 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 108, "y" : 1358 }, "b" : { "x" : 102, "y" : 1363 }, "c" : { "x" : 110, "y" : 1366 }, "type" : "ARROW" } } ], "trivial" : true }, { "id" : 354, "reactomeId" : 428206, "displayName" : "NAD(P)H", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 79, "y" : 1262 }, "minX" : 52, "maxX" : 181, "minY" : 1251, "maxY" : 1295, "prop" : { "x" : 52, "y" : 1251, "width" : 55, "height" : 22 }, "textPosition" : { "x" : 52, "y" : 1251 }, "connectors" : [ { "edgeId" : 66, "type" : "INPUT", "segments" : [ { "from" : { "x" : 113, "y" : 1270 }, "to" : { "x" : 181, "y" : 1295 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 356, "reactomeId" : 29368, "displayName" : "O2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 1295 }, "minX" : 63, "maxX" : 181, "minY" : 1279, "maxY" : 1310, "prop" : { "x" : 63, "y" : 1280, "width" : 32, "height" : 30 }, "textPosition" : { "x" : 67, "y" : 1284 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 90, "y" : 1285 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 66, "type" : "INPUT", "segments" : [ { "from" : { "x" : 98, "y" : 1295 }, "to" : { "x" : 181, "y" : 1295 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 360, "reactomeId" : 428218, "displayName" : "NAD(P)+", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 75, "y" : 1331 }, "minX" : 43, "maxX" : 180, "minY" : 1319, "maxY" : 1347, "prop" : { "x" : 43, "y" : 1319, "width" : 65, "height" : 25 }, "textPosition" : { "x" : 48, "y" : 1320 }, "connectors" : [ { "edgeId" : 66, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 114, "y" : 1335 }, "to" : { "x" : 180, "y" : 1347 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 122, "y" : 1332 }, "b" : { "x" : 114, "y" : 1335 }, "c" : { "x" : 120, "y" : 1340 }, "type" : "ARROW" } } ] }, { "id" : 363, "reactomeId" : 428206, "displayName" : "NAD(P)H", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 75, "y" : 1454 }, "minX" : 43, "maxX" : 182, "minY" : 1443, "maxY" : 1484, "prop" : { "x" : 43, "y" : 1443, "width" : 64, "height" : 22 }, "textPosition" : { "x" : 47, "y" : 1443 }, "connectors" : [ { "edgeId" : 70, "type" : "INPUT", "segments" : [ { "from" : { "x" : 113, "y" : 1462 }, "to" : { "x" : 182, "y" : 1484 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 367, "reactomeId" : 428218, "displayName" : "NAD(P)+", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 75, "y" : 1527 }, "minX" : 42, "maxX" : 182, "minY" : 1516, "maxY" : 1542, "prop" : { "x" : 42, "y" : 1516, "width" : 66, "height" : 23 }, "textPosition" : { "x" : 47, "y" : 1516 }, "connectors" : [ { "edgeId" : 70, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 114, "y" : 1531 }, "to" : { "x" : 182, "y" : 1542 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 121, "y" : 1528 }, "b" : { "x" : 114, "y" : 1531 }, "c" : { "x" : 120, "y" : 1536 }, "type" : "ARROW" } } ] }, { "id" : 240, "reactomeId" : 29368, "displayName" : "O2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 1488 }, "minX" : 63, "maxX" : 182, "minY" : 1472, "maxY" : 1503, "prop" : { "x" : 63, "y" : 1473, "width" : 32, "height" : 30 }, "textPosition" : { "x" : 67, "y" : 1477 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 90, "y" : 1478 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 70, "type" : "INPUT", "segments" : [ { "from" : { "x" : 98, "y" : 1487 }, "to" : { "x" : 182, "y" : 1484 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 370, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 80, "y" : 1769 }, "minX" : 60, "maxX" : 181, "minY" : 1740, "maxY" : 1784, "prop" : { "x" : 60, "y" : 1754, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 64, "y" : 1758 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 95, "y" : 1759 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 73, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 103, "y" : 1763 }, "to" : { "x" : 181, "y" : 1740 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 109, "y" : 1757 }, "b" : { "x" : 103, "y" : 1763 }, "c" : { "x" : 111, "y" : 1765 }, "type" : "ARROW" } } ], "trivial" : true }, { "id" : 374, "reactomeId" : 428206, "displayName" : "NAD(P)H", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 74, "y" : 1642 }, "minX" : 42, "maxX" : 181, "minY" : 1632, "maxY" : 1689, "prop" : { "x" : 42, "y" : 1632, "width" : 65, "height" : 21 }, "textPosition" : { "x" : 47, "y" : 1632 }, "connectors" : [ { "edgeId" : 73, "type" : "INPUT", "segments" : [ { "from" : { "x" : 97, "y" : 1659 }, "to" : { "x" : 181, "y" : 1689 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 247, "reactomeId" : 29368, "displayName" : "O2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 1682 }, "minX" : 63, "maxX" : 181, "minY" : 1666, "maxY" : 1697, "prop" : { "x" : 63, "y" : 1667, "width" : 32, "height" : 30 }, "textPosition" : { "x" : 67, "y" : 1671 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 90, "y" : 1672 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 73, "type" : "INPUT", "segments" : [ { "from" : { "x" : 98, "y" : 1683 }, "to" : { "x" : 181, "y" : 1689 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 248, "reactomeId" : 113528, "displayName" : "CO2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 79, "y" : 1938 }, "minX" : 59, "maxX" : 178, "minY" : 1910, "maxY" : 1953, "prop" : { "x" : 59, "y" : 1923, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 63, "y" : 1927 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 94, "y" : 1928 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 76, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 102, "y" : 1932 }, "to" : { "x" : 178, "y" : 1910 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 108, "y" : 1926 }, "b" : { "x" : 102, "y" : 1932 }, "c" : { "x" : 110, "y" : 1934 }, "type" : "ARROW" } } ], "trivial" : true }, { "id" : 376, "reactomeId" : 428218, "displayName" : "NAD(P)+", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 75, "y" : 1728 }, "minX" : 42, "maxX" : 181, "minY" : 1716, "maxY" : 1741, "prop" : { "x" : 42, "y" : 1716, "width" : 66, "height" : 25 }, "textPosition" : { "x" : 47, "y" : 1717 }, "connectors" : [ { "edgeId" : 73, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 114, "y" : 1731 }, "to" : { "x" : 181, "y" : 1740 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 121, "y" : 1728 }, "b" : { "x" : 114, "y" : 1731 }, "c" : { "x" : 120, "y" : 1736 }, "type" : "ARROW" } } ] }, { "id" : 121, "reactomeId" : 1131017, "displayName" : "4alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 182, "y" : 2270 }, "minX" : 120, "maxX" : 246, "minY" : 2198, "maxY" : 2339, "prop" : { "x" : 120, "y" : 2234, "width" : 125, "height" : 72 }, "textPosition" : { "x" : 120, "y" : 2238 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 240, "y" : 2239 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 120, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 181, "y" : 2231 }, "to" : { "x" : 180, "y" : 2198 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 177, "y" : 2224 }, "b" : { "x" : 181, "y" : 2231 }, "c" : { "x" : 185, "y" : 2224 }, "type" : "ARROW" } }, { "edgeId" : 124, "type" : "INPUT", "segments" : [ { "from" : { "x" : 180, "y" : 2309 }, "to" : { "x" : 180, "y" : 2339 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 123, "reactomeId" : 1121733, "displayName" : "Methylsterol monooxygenase", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 321, "y" : 2364 }, "minX" : 189, "maxX" : 371, "minY" : 2346, "maxY" : 2382, "prop" : { "x" : 271, "y" : 2346, "width" : 100, "height" : 36 }, "textPosition" : { "x" : 271, "y" : 2346 }, "connectors" : [ { "edgeId" : 124, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 265, "y" : 2364 }, "to" : { "x" : 197, "y" : 2364 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 193, "y" : 2364 }, "r" : 4, "type" : "CIRCLE", "empty" : true } } ] }, { "id" : 379, "reactomeId" : 428206, "displayName" : "NAD(P)H", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 79, "y" : 1899 }, "minX" : 52, "maxX" : 178, "minY" : 1888, "maxY" : 1910, "prop" : { "x" : 52, "y" : 1888, "width" : 55, "height" : 22 }, "textPosition" : { "x" : 52, "y" : 1888 }, "connectors" : [ { "edgeId" : 76, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 113, "y" : 1902 }, "to" : { "x" : 178, "y" : 1910 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 120, "y" : 1899 }, "b" : { "x" : 113, "y" : 1902 }, "c" : { "x" : 119, "y" : 1907 }, "type" : "ARROW" } } ] }, { "id" : 125, "reactomeId" : 1130738, "displayName" : "4alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 182, "y" : 2466 }, "minX" : 120, "maxX" : 246, "minY" : 2391, "maxY" : 2535, "prop" : { "x" : 120, "y" : 2437, "width" : 125, "height" : 58 }, "textPosition" : { "x" : 120, "y" : 2441 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 240, "y" : 2442 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 124, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 181, "y" : 2434 }, "to" : { "x" : 181, "y" : 2391 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 177, "y" : 2427 }, "b" : { "x" : 181, "y" : 2434 }, "c" : { "x" : 185, "y" : 2427 }, "type" : "ARROW" } }, { "edgeId" : 127, "type" : "INPUT", "segments" : [ { "from" : { "x" : 181, "y" : 2498 }, "to" : { "x" : 181, "y" : 2535 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 253, "reactomeId" : 29364, "displayName" : "NADPH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 87, "y" : 2013 }, "minX" : 59, "maxX" : 180, "minY" : 1997, "maxY" : 2028, "prop" : { "x" : 59, "y" : 1998, "width" : 57, "height" : 30 }, "textPosition" : { "x" : 64, "y" : 2002 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 111, "y" : 2003 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 79, "type" : "INPUT", "segments" : [ { "from" : { "x" : 119, "y" : 2016 }, "to" : { "x" : 180, "y" : 2026 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 381, "reactomeId" : 428218, "displayName" : "NAD(P)+", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 79, "y" : 1850 }, "minX" : 51, "maxX" : 178, "minY" : 1839, "maxY" : 1869, "prop" : { "x" : 51, "y" : 1839, "width" : 57, "height" : 22 }, "textPosition" : { "x" : 52, "y" : 1839 }, "connectors" : [ { "edgeId" : 76, "type" : "INPUT", "segments" : [ { "from" : { "x" : 114, "y" : 1855 }, "to" : { "x" : 178, "y" : 1869 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 254, "reactomeId" : 29366, "displayName" : "NADP+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 87, "y" : 2063 }, "minX" : 58, "maxX" : 180, "minY" : 2047, "maxY" : 2078, "prop" : { "x" : 58, "y" : 2048, "width" : 58, "height" : 30 }, "textPosition" : { "x" : 63, "y" : 2052 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 111, "y" : 2053 }, "r" : 6, "type" : "CIRCLE", "empty" : true } }, "connectors" : [ { "edgeId" : 79, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 119, "y" : 2061 }, "to" : { "x" : 180, "y" : 2057 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 126, "y" : 2057 }, "b" : { "x" : 119, "y" : 2061 }, "c" : { "x" : 126, "y" : 2065 }, "type" : "ARROW" } } ] } ], "edges" : [ { "id" : 2, "reactomeId" : 1119792, "displayName" : "Farnesyl-diphosphate farnesyltransferase", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 182, "y" : 105 }, "minX" : 176, "maxX" : 188, "minY" : 73, "maxY" : 121, "segments" : [ { "from" : { "x" : 182, "y" : 73 }, "to" : { "x" : 182, "y" : 105 } }, { "from" : { "x" : 182, "y" : 105 }, "to" : { "x" : 182, "y" : 121 } } ], "reactionShape" : { "a" : { "x" : 176, "y" : 99 }, "b" : { "x" : 188, "y" : 111 }, "type" : "BOX", "empty" : true }, "inputs" : [ { "id" : 424 } ], "outputs" : [ { "id" : 425, "points" : [ { "x" : 182, "y" : 153 } ] }, { "id" : 174, "points" : [ { "x" : 99, "y" : 127 } ] } ], "catalysts" : [ { "id" : 6, "points" : [ { "x" : 260, "y" : 105 } ] } ] }, { "id" : 66, "reactomeId" : 1120472, "displayName" : "4,4-dimethyl-5alpha-cholesta-8,24-dien-3-beta-ol+NAD(P)H+O2->4alpha-hydroxymethyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 181, "y" : 1327 }, "minX" : 175, "maxX" : 187, "minY" : 1295, "maxY" : 1347, "segments" : [ { "from" : { "x" : 181, "y" : 1295 }, "to" : { "x" : 181, "y" : 1327 } }, { "from" : { "x" : 181, "y" : 1327 }, "to" : { "x" : 180, "y" : 1347 } } ], "reactionShape" : { "a" : { "x" : 175, "y" : 1321 }, "b" : { "x" : 187, "y" : 1333 }, "type" : "BOX", "empty" : true }, "inputs" : [ { "id" : 31, "points" : [ { "x" : 181, "y" : 1252 } ] }, { "id" : 354, "points" : [ { "x" : 113, "y" : 1270 } ] }, { "id" : 356, "points" : [ { "x" : 98, "y" : 1295 } ] } ], "outputs" : [ { "id" : 67, "points" : [ { "x" : 180, "y" : 1362 } ] }, { "id" : 352, "points" : [ { "x" : 102, "y" : 1363 } ] }, { "id" : 360, "points" : [ { "x" : 114, "y" : 1335 } ] } ], "catalysts" : [ { "id" : 69, "points" : [ { "x" : 314, "y" : 1489 }, { "x" : 264, "y" : 1326 } ] } ] }, { "id" : 130, "reactomeId" : 1120059, "displayName" : "4alpha-carboxy-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)+->5alpha-cholesta-8,24-dien-3-one+NAD(P)H+CO2", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 182, "y" : 2711 }, "minX" : 176, "maxX" : 188, "minY" : 2695, "maxY" : 2735, "segments" : [ { "from" : { "x" : 182, "y" : 2695 }, "to" : { "x" : 182, "y" : 2711 } }, { "from" : { "x" : 182, "y" : 2711 }, "to" : { "x" : 184, "y" : 2735 } } ], "reactionShape" : { "a" : { "x" : 176, "y" : 2705 }, "b" : { "x" : 188, "y" : 2717 }, "type" : "BOX", "empty" : true }, "inputs" : [ { "id" : 128, "points" : [ { "x" : 182, "y" : 2674 } ] }, { "id" : 416, "points" : [ { "x" : 110, "y" : 2686 } ] } ], "outputs" : [ { "id" : 131, "points" : [ { "x" : 182, "y" : 2768 } ] }, { "id" : 278, "points" : [ { "x" : 98, "y" : 2759 } ] }, { "id" : 414, "points" : [ { "x" : 109, "y" : 2727 } ] } ] }, { "id" : 132, "reactomeId" : 1121540, "displayName" : "5alpha-cholesta-8,24-dien-3-one+NADPH->zymosterol+NADP+", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 182, "y" : 2845 }, "minX" : 176, "maxX" : 188, "minY" : 2833, "maxY" : 2862, "segments" : [ { "from" : { "x" : 182, "y" : 2833 }, "to" : { "x" : 182, "y" : 2845 } }, { "from" : { "x" : 182, "y" : 2845 }, "to" : { "x" : 182, "y" : 2862 } } ], "reactionShape" : { "a" : { "x" : 176, "y" : 2839 }, "b" : { "x" : 188, "y" : 2851 }, "type" : "BOX", "empty" : true }, "inputs" : [ { "id" : 131, "points" : [ { "x" : 182, "y" : 2818 } ] }, { "id" : 284, "points" : [ { "x" : 107, "y" : 2825 } ] } ], "outputs" : [ { "id" : 133, "points" : [ { "x" : 182, "y" : 2878 } ] }, { "id" : 285, "points" : [ { "x" : 107, "y" : 2864 } ] } ] }, { "id" : 134, "reactomeId" : 1121173, "displayName" : "zymosterol->5alpha-cholesta-7,24-dien-3beta-ol", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 182, "y" : 2931 }, "minX" : 176, "maxX" : 188, "minY" : 2914, "maxY" : 2963, "segments" : [ { "from" : { "x" : 182, "y" : 2914 }, "to" : { "x" : 182, "y" : 2931 } }, { "from" : { "x" : 182, "y" : 2931 }, "to" : { "x" : 182, "y" : 2963 } } ], "endShape" : { "a" : { "x" : 178, "y" : 2956 }, "b" : { "x" : 182, "y" : 2963 }, "c" : { "x" : 186, "y" : 2956 }, "type" : "ARROW" }, "reactionShape" : { "a" : { "x" : 176, "y" : 2925 }, "b" : { "x" : 188, "y" : 2937 }, "type" : "BOX", "empty" : true }, "inputs" : [ { "id" : 133 } ], "outputs" : [ { "id" : 135 } ], "catalysts" : [ { "id" : 136, "points" : [ { "x" : 257, "y" : 2932 } ] } ] }, { "id" : 70, "reactomeId" : 1121133, "displayName" : "4alpha-hydroxymethyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-formyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 182, "y" : 1512 }, "minX" : 176, "maxX" : 188, "minY" : 1484, "maxY" : 1542, "segments" : [ { "from" : { "x" : 182, "y" : 1484 }, "to" : { "x" : 182, "y" : 1512 } }, { "from" : { "x" : 182, "y" : 1512 }, "to" : { "x" : 182, "y" : 1542 } } ], "reactionShape" : { "a" : { "x" : 176, "y" : 1506 }, "b" : { "x" : 188, "y" : 1518 }, "type" : "BOX", "empty" : true }, "inputs" : [ { "id" : 67, "points" : [ { "x" : 182, "y" : 1454 } ] }, { "id" : 240, "points" : [ { "x" : 98, "y" : 1487 } ] }, { "id" : 363, "points" : [ { "x" : 113, "y" : 1462 } ] } ], "outputs" : [ { "id" : 72, "points" : [ { "x" : 182, "y" : 1578 } ] }, { "id" : 392, "points" : [ { "x" : 101, "y" : 1567 } ], "stoichiometry" : 2 }, { "id" : 367, "points" : [ { "x" : 114, "y" : 1531 } ] } ], "catalysts" : [ { "id" : 69, "points" : [ { "x" : 262, "y" : 1512 } ] } ] }, { "id" : 7, "reactomeId" : 1120616, "displayName" : "presqualene diphosphate+NAD(P)H->squalene+NAD(P)++diphosphate", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 182, "y" : 233 }, "minX" : 176, "maxX" : 188, "minY" : 217, "maxY" : 257, "segments" : [ { "from" : { "x" : 182, "y" : 217 }, "to" : { "x" : 182, "y" : 233 } }, { "from" : { "x" : 182, "y" : 233 }, "to" : { "x" : 181, "y" : 257 } } ], "reactionShape" : { "a" : { "x" : 176, "y" : 227 }, "b" : { "x" : 188, "y" : 239 }, "type" : "BOX", "empty" : true }, "inputs" : [ { "id" : 425, "points" : [ { "x" : 182, "y" : 189 } ] }, { "id" : 330, "points" : [ { "x" : 114, "y" : 210 } ] } ], "outputs" : [ { "id" : 340, "points" : [ { "x" : 115, "y" : 251 } ] }, { "id" : 184, "points" : [ { "x" : 181, "y" : 282 } ] }, { "id" : 177, "points" : [ { "x" : 99, "y" : 283 } ] } ], "catalysts" : [ { "id" : 176, "points" : [ { "x" : 260, "y" : 234 } ] } ] }, { "id" : 73, "reactomeId" : 1119749, "displayName" : "4alpha-formyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-carboxy-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 182, "y" : 1714 }, "minX" : 176, "maxX" : 188, "minY" : 1689, "maxY" : 1740, "segments" : [ { "from" : { "x" : 181, "y" : 1689 }, "to" : { "x" : 182, "y" : 1714 } }, { "from" : { "x" : 182, "y" : 1714 }, "to" : { "x" : 181, "y" : 1740 } } ], "reactionShape" : { "a" : { "x" : 176, "y" : 1708 }, "b" : { "x" : 188, "y" : 1720 }, "type" : "BOX", "empty" : true }, "inputs" : [ { "id" : 72, "points" : [ { "x" : 181, "y" : 1656 } ] }, { "id" : 247, "points" : [ { "x" : 98, "y" : 1683 } ] }, { "id" : 374, "points" : [ { "x" : 97, "y" : 1659 } ] } ], "outputs" : [ { "id" : 74, "points" : [ { "x" : 181, "y" : 1771 } ] }, { "id" : 370, "points" : [ { "x" : 103, "y" : 1763 } ] }, { "id" : 376, "points" : [ { "x" : 114, "y" : 1731 } ] } ], "catalysts" : [ { "id" : 69, "points" : [ { "x" : 315, "y" : 1537 }, { "x" : 267, "y" : 1714 } ] } ] }, { "id" : 137, "reactomeId" : 1121038, "displayName" : "5alpha-cholesta-7,24-dien-3beta-ol+O2+NAD(P)H->7-dehydrodesmosterol+H2O+NAD(P)+", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 182, "y" : 3075 }, "minX" : 176, "maxX" : 188, "minY" : 3048, "maxY" : 3110, "segments" : [ { "from" : { "x" : 181, "y" : 3048 }, "to" : { "x" : 182, "y" : 3075 } }, { "from" : { "x" : 182, "y" : 3075 }, "to" : { "x" : 183, "y" : 3110 } } ], "reactionShape" : { "a" : { "x" : 176, "y" : 3069 }, "b" : { "x" : 188, "y" : 3081 }, "type" : "BOX", "empty" : true }, "inputs" : [ { "id" : 135, "points" : [ { "x" : 181, "y" : 3013 } ] }, { "id" : 293, "points" : [ { "x" : 89, "y" : 3048 } ] }, { "id" : 421, "points" : [ { "x" : 104, "y" : 3020 } ] } ], "outputs" : [ { "id" : 139, "points" : [ { "x" : 182, "y" : 3151 } ] }, { "id" : 419, "points" : [ { "x" : 93, "y" : 3125 } ], "stoichiometry" : 2 }, { "id" : 423, "points" : [ { "x" : 105, "y" : 3092 } ] } ] }, { "id" : 76, "reactomeId" : 1120979, "displayName" : "4alpha-carboxy-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)+->4alpha-methyl-5alpha-cholesta-8,24-dien-3-one+NAD(P)H+CO2", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 178, "y" : 1888 }, "minX" : 172, "maxX" : 184, "minY" : 1869, "maxY" : 1910, "segments" : [ { "from" : { "x" : 178, "y" : 1869 }, "to" : { "x" : 178, "y" : 1888 } }, { "from" : { "x" : 178, "y" : 1888 }, "to" : { "x" : 178, "y" : 1910 } } ], "reactionShape" : { "a" : { "x" : 172, "y" : 1882 }, "b" : { "x" : 184, "y" : 1894 }, "type" : "BOX", "empty" : true }, "inputs" : [ { "id" : 74, "points" : [ { "x" : 179, "y" : 1849 } ] }, { "id" : 381, "points" : [ { "x" : 114, "y" : 1855 } ] } ], "outputs" : [ { "id" : 77, "points" : [ { "x" : 179, "y" : 1942 } ] }, { "id" : 248, "points" : [ { "x" : 102, "y" : 1932 } ] }, { "id" : 379, "points" : [ { "x" : 113, "y" : 1902 } ] } ] }, { "id" : 12, "reactomeId" : 1120707, "displayName" : "squalene+NADPH+O2->(S)-2,3-Epoxysqualene+NADP++H2O", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 182, "y" : 371 }, "minX" : 176, "maxX" : 188, "minY" : 354, "maxY" : 401, "segments" : [ { "from" : { "x" : 182, "y" : 354 }, "to" : { "x" : 182, "y" : 371 } }, { "from" : { "x" : 182, "y" : 371 }, "to" : { "x" : 183, "y" : 401 } } ], "reactionShape" : { "a" : { "x" : 176, "y" : 365 }, "b" : { "x" : 188, "y" : 377 }, "type" : "BOX", "empty" : true }, "inputs" : [ { "id" : 184, "points" : [ { "x" : 182, "y" : 318 } ] }, { "id" : 179, "points" : [ { "x" : 111, "y" : 356 } ] }, { "id" : 178, "points" : [ { "x" : 98, "y" : 330 } ] } ], "outputs" : [ { "id" : 426, "points" : [ { "x" : 182, "y" : 427 } ] }, { "id" : 180, "points" : [ { "x" : 111, "y" : 392 } ] }, { "id" : 183, "points" : [ { "x" : 102, "y" : 419 } ] } ] }, { "id" : 140, "reactomeId" : 1121323, "displayName" : "7-dehydrodesmosterol+NADPH->desmosterol+NADP+", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 178, "y" : 3235 }, "minX" : 172, "maxX" : 184, "minY" : 3222, "maxY" : 3253, "segments" : [ { "from" : { "x" : 178, "y" : 3222 }, "to" : { "x" : 178, "y" : 3235 } }, { "from" : { "x" : 178, "y" : 3235 }, "to" : { "x" : 178, "y" : 3253 } } ], "reactionShape" : { "a" : { "x" : 172, "y" : 3229 }, "b" : { "x" : 184, "y" : 3241 }, "type" : "BOX", "empty" : true }, "inputs" : [ { "id" : 139, "points" : [ { "x" : 180, "y" : 3201 } ] }, { "id" : 296, "points" : [ { "x" : 102, "y" : 3213 } ] } ], "outputs" : [ { "id" : 141, "points" : [ { "x" : 178, "y" : 3276 } ] }, { "id" : 297, "points" : [ { "x" : 102, "y" : 3251 } ] } ] }, { "id" : 142, "reactomeId" : 1119700, "displayName" : "desmosterol+NADPH->cholesterol+NADP+", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 178, "y" : 3338 }, "minX" : 172, "maxX" : 184, "minY" : 3326, "maxY" : 3357, "segments" : [ { "from" : { "x" : 178, "y" : 3326 }, "to" : { "x" : 178, "y" : 3338 } }, { "from" : { "x" : 178, "y" : 3338 }, "to" : { "x" : 178, "y" : 3357 } } ], "reactionShape" : { "a" : { "x" : 172, "y" : 3332 }, "b" : { "x" : 184, "y" : 3344 }, "type" : "BOX", "empty" : true }, "inputs" : [ { "id" : 141, "points" : [ { "x" : 178, "y" : 3312 } ] }, { "id" : 301, "points" : [ { "x" : 102, "y" : 3315 } ] } ], "outputs" : [ { "id" : 298, "points" : [ { "x" : 178, "y" : 3372 } ] }, { "id" : 302, "points" : [ { "x" : 102, "y" : 3356 } ] } ] }, { "id" : 79, "reactomeId" : 1120411, "displayName" : "4alpha-methyl-5alpha-cholesta-8,24-dien-3-one+NADPH->4-alpha-methyl zymosterol+NADP+", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 180, "y" : 2041 }, "minX" : 174, "maxX" : 186, "minY" : 2026, "maxY" : 2057, "segments" : [ { "from" : { "x" : 180, "y" : 2026 }, "to" : { "x" : 180, "y" : 2041 } }, { "from" : { "x" : 180, "y" : 2041 }, "to" : { "x" : 180, "y" : 2057 } } ], "reactionShape" : { "a" : { "x" : 174, "y" : 2035 }, "b" : { "x" : 186, "y" : 2047 }, "type" : "BOX", "empty" : true }, "inputs" : [ { "id" : 77, "points" : [ { "x" : 180, "y" : 2006 } ] }, { "id" : 253, "points" : [ { "x" : 119, "y" : 2016 } ] } ], "outputs" : [ { "id" : 80, "points" : [ { "x" : 180, "y" : 2072 } ] }, { "id" : 254, "points" : [ { "x" : 119, "y" : 2061 } ] } ] }, { "id" : 18, "reactomeId" : 1121018, "displayName" : "Lanosterol synthase", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 182, "y" : 498 }, "minX" : 176, "maxX" : 188, "minY" : 463, "maxY" : 523, "segments" : [ { "from" : { "x" : 182, "y" : 463 }, "to" : { "x" : 182, "y" : 498 } }, { "from" : { "x" : 182, "y" : 498 }, "to" : { "x" : 182, "y" : 523 } } ], "endShape" : { "a" : { "x" : 178, "y" : 516 }, "b" : { "x" : 182, "y" : 523 }, "c" : { "x" : 186, "y" : 516 }, "type" : "ARROW" }, "reactionShape" : { "a" : { "x" : 176, "y" : 492 }, "b" : { "x" : 188, "y" : 504 }, "type" : "BOX", "empty" : true }, "inputs" : [ { "id" : 426 } ], "outputs" : [ { "id" : 318 } ] }, { "id" : 20, "reactomeId" : 1120767, "displayName" : "lanosterol+NADPH+O2->4,4-dimethyl-14alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol+NADP++H2O", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 182, "y" : 608 }, "minX" : 176, "maxX" : 188, "minY" : 581, "maxY" : 625, "segments" : [ { "from" : { "x" : 182, "y" : 581 }, "to" : { "x" : 182, "y" : 608 } }, { "from" : { "x" : 182, "y" : 608 }, "to" : { "x" : 182, "y" : 625 } } ], "reactionShape" : { "a" : { "x" : 176, "y" : 602 }, "b" : { "x" : 188, "y" : 614 }, "type" : "BOX", "empty" : true }, "inputs" : [ { "id" : 318, "points" : [ { "x" : 182, "y" : 559 } ] }, { "id" : 190, "points" : [ { "x" : 98, "y" : 562 } ] }, { "id" : 191, "points" : [ { "x" : 111, "y" : 587 } ] } ], "outputs" : [ { "id" : 186, "points" : [ { "x" : 102, "y" : 651 } ] }, { "id" : 21, "points" : [ { "x" : 182, "y" : 655 } ] }, { "id" : 192, "points" : [ { "x" : 111, "y" : 623 } ] } ] }, { "id" : 23, "reactomeId" : 1121216, "displayName" : "4,4-dimethyl-14alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol+NADPH+O2->4,4-dimethyl-14alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol+NADP++H2O", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 182, "y" : 791 }, "minX" : 176, "maxX" : 188, "minY" : 775, "maxY" : 805, "segments" : [ { "from" : { "x" : 182, "y" : 775 }, "to" : { "x" : 182, "y" : 791 } }, { "from" : { "x" : 182, "y" : 791 }, "to" : { "x" : 182, "y" : 805 } } ], "reactionShape" : { "a" : { "x" : 176, "y" : 785 }, "b" : { "x" : 188, "y" : 797 }, "type" : "BOX", "empty" : true }, "inputs" : [ { "id" : 21, "points" : [ { "x" : 182, "y" : 747 } ] }, { "id" : 199, "points" : [ { "x" : 98, "y" : 745 } ] }, { "id" : 200, "points" : [ { "x" : 111, "y" : 772 } ] } ], "outputs" : [ { "id" : 195, "points" : [ { "x" : 102, "y" : 805 } ], "stoichiometry" : 2 }, { "id" : 24, "points" : [ { "x" : 182, "y" : 843 } ] }, { "id" : 201, "points" : [ { "x" : 111, "y" : 830 } ] } ] }, { "id" : 120, "reactomeId" : 1121120, "displayName" : "4-alpha-methyl zymosterol+NAD(P)H+O2->4alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 180, "y" : 2171 }, "minX" : 174, "maxX" : 186, "minY" : 2150, "maxY" : 2198, "segments" : [ { "from" : { "x" : 180, "y" : 2150 }, "to" : { "x" : 180, "y" : 2171 } }, { "from" : { "x" : 180, "y" : 2171 }, "to" : { "x" : 180, "y" : 2198 } } ], "reactionShape" : { "a" : { "x" : 174, "y" : 2165 }, "b" : { "x" : 186, "y" : 2177 }, "type" : "BOX", "empty" : true }, "inputs" : [ { "id" : 80, "points" : [ { "x" : 180, "y" : 2122 } ] }, { "id" : 262, "points" : [ { "x" : 106, "y" : 2158 } ] }, { "id" : 388, "points" : [ { "x" : 121, "y" : 2133 } ] } ], "outputs" : [ { "id" : 121, "points" : [ { "x" : 181, "y" : 2231 } ] }, { "id" : 386, "points" : [ { "x" : 110, "y" : 2223 } ] }, { "id" : 390, "points" : [ { "x" : 122, "y" : 2194 } ] } ], "catalysts" : [ { "id" : 222, "points" : [ { "x" : 257, "y" : 2171 } ] } ] }, { "id" : 26, "reactomeId" : 1121474, "displayName" : "4,4-dimethyl-14alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol+NADPH+O2->4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol+NADP++H2O+formate", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 182, "y" : 980 }, "minX" : 176, "maxX" : 188, "minY" : 952, "maxY" : 1018, "segments" : [ { "from" : { "x" : 182, "y" : 952 }, "to" : { "x" : 182, "y" : 980 } }, { "from" : { "x" : 182, "y" : 980 }, "to" : { "x" : 182, "y" : 1018 } } ], "reactionShape" : { "a" : { "x" : 176, "y" : 974 }, "b" : { "x" : 188, "y" : 986 }, "type" : "BOX", "empty" : true }, "inputs" : [ { "id" : 24, "points" : [ { "x" : 182, "y" : 921 } ] }, { "id" : 209, "points" : [ { "x" : 98, "y" : 916 } ] }, { "id" : 210, "points" : [ { "x" : 111, "y" : 946 } ] } ], "outputs" : [ { "id" : 204, "points" : [ { "x" : 102, "y" : 1046 } ] }, { "id" : 205, "points" : [ { "x" : 111, "y" : 1018 } ] }, { "id" : 27, "points" : [ { "x" : 182, "y" : 1043 } ] }, { "id" : 211, "points" : [ { "x" : 111, "y" : 994 } ] } ] }, { "id" : 124, "reactomeId" : 1121309, "displayName" : "4alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 181, "y" : 2364 }, "minX" : 175, "maxX" : 187, "minY" : 2339, "maxY" : 2391, "segments" : [ { "from" : { "x" : 180, "y" : 2339 }, "to" : { "x" : 181, "y" : 2364 } }, { "from" : { "x" : 181, "y" : 2364 }, "to" : { "x" : 181, "y" : 2391 } } ], "reactionShape" : { "a" : { "x" : 175, "y" : 2358 }, "b" : { "x" : 187, "y" : 2370 }, "type" : "BOX", "empty" : true }, "inputs" : [ { "id" : 121, "points" : [ { "x" : 180, "y" : 2309 } ] }, { "id" : 270, "points" : [ { "x" : 94, "y" : 2344 } ] }, { "id" : 400, "points" : [ { "x" : 109, "y" : 2315 } ] } ], "outputs" : [ { "id" : 125, "points" : [ { "x" : 181, "y" : 2434 } ] }, { "id" : 398, "points" : [ { "x" : 98, "y" : 2418 } ], "stoichiometry" : 2 }, { "id" : 402, "points" : [ { "x" : 110, "y" : 2386 } ] } ], "catalysts" : [ { "id" : 123, "points" : [ { "x" : 265, "y" : 2364 } ] } ] }, { "id" : 30, "reactomeId" : 1120304, "displayName" : "4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol+NADPH->4,4-dimethyl-5alpha-cholesta-8,24-dien-3-beta-ol+NADP+", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 182, "y" : 1145 }, "minX" : 176, "maxX" : 188, "minY" : 1133, "maxY" : 1162, "segments" : [ { "from" : { "x" : 182, "y" : 1133 }, "to" : { "x" : 182, "y" : 1145 } }, { "from" : { "x" : 182, "y" : 1145 }, "to" : { "x" : 182, "y" : 1162 } } ], "reactionShape" : { "a" : { "x" : 176, "y" : 1139 }, "b" : { "x" : 188, "y" : 1151 }, "type" : "BOX", "empty" : true }, "inputs" : [ { "id" : 27, "points" : [ { "x" : 182, "y" : 1121 } ] }, { "id" : 215, "points" : [ { "x" : 111, "y" : 1127 } ] } ], "outputs" : [ { "id" : 31, "points" : [ { "x" : 182, "y" : 1188 } ] }, { "id" : 216, "points" : [ { "x" : 111, "y" : 1164 } ] } ] }, { "id" : 127, "reactomeId" : 1120443, "displayName" : "4alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-carboxy-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 182, "y" : 2552 }, "minX" : 176, "maxX" : 188, "minY" : 2535, "maxY" : 2562, "segments" : [ { "from" : { "x" : 181, "y" : 2535 }, "to" : { "x" : 182, "y" : 2552 } }, { "from" : { "x" : 182, "y" : 2552 }, "to" : { "x" : 180, "y" : 2562 } } ], "reactionShape" : { "a" : { "x" : 176, "y" : 2546 }, "b" : { "x" : 188, "y" : 2558 }, "type" : "BOX", "empty" : true }, "inputs" : [ { "id" : 125, "points" : [ { "x" : 181, "y" : 2498 } ] }, { "id" : 277, "points" : [ { "x" : 94, "y" : 2528 } ] }, { "id" : 408, "points" : [ { "x" : 102, "y" : 2510 } ] } ], "outputs" : [ { "id" : 128, "points" : [ { "x" : 181, "y" : 2610 } ] }, { "id" : 406, "points" : [ { "x" : 98, "y" : 2594 } ] }, { "id" : 410, "points" : [ { "x" : 110, "y" : 2562 } ] } ], "catalysts" : [ { "id" : 224, "points" : [ { "x" : 267, "y" : 2552 } ] } ] } ], "compartments" : [ { "id" : 1, "reactomeId" : 70101, "displayName" : "cytosol", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 229, "y" : 1713 }, "minX" : 4, "maxX" : 455, "minY" : 4, "maxY" : 3423, "prop" : { "x" : 4, "y" : 4, "width" : 451, "height" : 3419 }, "textPosition" : { "x" : 382, "y" : 17 }, "insets" : { "x" : 14, "y" : 14, "width" : 431, "height" : 3399 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 2, 6, 7, 12, 18, 20, 21, 23, 24, 26, 27, 30, 31, 66, 67, 70, 72, 73, 74, 76, 77, 79, 80, 69, 120, 121, 124, 127, 123, 125, 128, 130, 131, 132, 133, 134, 135, 136, 137, 139, 140, 141, 142, 174, 176, 177, 178, 179, 180, 183, 184, 186, 190, 191, 192, 195, 199, 200, 201, 204, 205, 209, 210, 211, 215, 216, 222, 224, 240, 248, 253, 254, 262, 270, 277, 278, 284, 285, 293, 296, 297, 298, 301, 302, 318, 330, 352, 354, 356, 360, 340, 363, 367, 247, 370, 374, 376, 379, 381, 386, 388, 390, 392, 398, 400, 402, 406, 410, 408, 414, 416, 419, 421, 423, 425, 426, 424 ] } ], "notes" : [ ], "links" : [ ], "shadows" : [ ], "minX" : 4, "maxX" : 455, "minY" : 4, "maxY" : 3423, "disease" : false }