Plant Reactome Pathway Database - Plant Reactome Pathway Database

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compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:11369132] Elser, Justin, 2025-03-26
dbId	11377754
displayName	Recruitment of CDC45
eventOf	[Pathway:R-VUN-9645850] Activation of pre-replication complex - Vigna unguiculata
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Reaction:R-VUN-9645845] Association of RPA proteins with Pre-RC at origin - Vigna unguiculata
inferredFrom	[Reaction:R-OSA-9645867] Recruitment of CDC45 - Oryza sativa
input	[Complex:R-VUN-9646037] MCM10:active pre-RC [Complex:R-VUN-9645982] TOPBP1:CDC45 [nucleoplasm]
isInDisease	false
isInferred	true
name	Recruitment of CDC45
output	[Complex:R-VUN-9645863] MCM10:active pre-RC:CDC45:TOPBP1 [nucleoplasm]
precedingEvent	[Reaction:R-VUN-9645934] Association of TOPBP1 with CDC45 - Vigna unguiculata
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9823415] Vigna unguiculata
stId	R-VUN-9645867
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

(hasEvent)	[Pathway:R-VUN-9645850] Activation of pre-replication complex - Vigna unguiculata
(precedingEvent)	[Reaction:R-VUN-9645845] Association of RPA proteins with Pre-RC at origin - Vigna unguiculata
(inferredTo)	[Reaction:R-OSA-9645867] Recruitment of CDC45 - Oryza sativa