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Binding of DNA polymerase epsilon at origin

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compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:11028643] Elser, Justin, 2025-03-25
dbId	11043648
displayName	Binding of DNA polymerase epsilon at origin
eventOf	[Pathway:R-TDI-9645850] Activation of pre-replication complex - Triticum dicoccoides
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Reaction:R-TDI-9645813] Binding of DNA polymerase alpha:primase at origin - Triticum dicoccoides
inferredFrom	[Reaction:R-OSA-9645988] Binding of DNA polymerase epsilon at origin - Oryza sativa
input	[OtherEntity:R-ALL-1599044] origin of replication [nucleoplasm] [Complex:R-TDI-9646046] POLE [nucleoplasm]
isInDisease	false
isInferred	true
name	Binding of DNA polymerase epsilon at origin
output	[Complex:R-TDI-9645974] POLE:origin complex [nucleoplasm]
precedingEvent	[Reaction:R-TDI-9645845] Association of RPA proteins with Pre-RC at origin - Triticum dicoccoides
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9622673] Triticum dicoccoides
stId	R-TDI-9645988
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

Referrals

(hasEvent)	[Pathway:R-TDI-9645850] Activation of pre-replication complex - Triticum dicoccoides
(precedingEvent)	[Reaction:R-TDI-9645813] Binding of DNA polymerase alpha:primase at origin - Triticum dicoccoides
(inferredTo)	[Reaction:R-OSA-9645988] Binding of DNA polymerase epsilon at origin - Oryza sativa

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