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iminoaspartate+dihydroxy-acetone-phosphate->quinolinate+H2O+phosphate

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catalystActivity	[CatalystActivity:10942358] quinolinate synthetase A activity of Fe-S metabolism associated domain containing protein (LOC_OS12G19304.1) [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10941596] Elser, Justin, 2025-03-25
dbId	10942360
displayName	iminoaspartate+dihydroxy-acetone-phosphate->quinolinate+H2O+phosphate
eventOf	[Pathway:R-SIT-1119384] NAD biosynthesis I (from aspartate) - Setaria italica
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Reaction:R-SIT-1121149] Nicotinate-nucleotide pyrophosphorylase (carboxylating) - Setaria italica
inferredFrom	[Reaction:R-OSA-1119946] iminoaspartate+dihydroxy-acetone-phosphate->quinolinate+H2O+phosphate - Oryza sativa
input	[SimpleEntity:R-ALL-75970] DHAP [cytosol] [SimpleEntity:R-ALL-1130937] iminoaspartate [cytoplasm]
isInDisease	false
isInferred	true
name	iminoaspartate+dihydroxy-acetone-phosphate->quinolinate+H2O+phosphate QUINOLINATE-SYNTHA-RXN biochemicalReaction61652
output	2 × [SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol] [SimpleEntity:R-ALL-197238] QUIN [cytosol]
precedingEvent	[Reaction:R-SIT-1120675] O2+L-aspartate->H2O2+iminoaspartate - Setaria italica
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9030295] Setaria italica
stId	R-SIT-1119946
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

Referrals

(hasEvent)	[Pathway:R-SIT-1119384] NAD biosynthesis I (from aspartate) - Setaria italica
(precedingEvent)	[Reaction:R-SIT-1121149] Nicotinate-nucleotide pyrophosphorylase (carboxylating) - Setaria italica
(inferredTo)	[Reaction:R-OSA-1119946] iminoaspartate+dihydroxy-acetone-phosphate->quinolinate+H2O+phosphate - Oryza sativa