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Formation of sliding clamp

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compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:11357575] Elser, Justin, 2025-03-26
dbId	11367198
displayName	Formation of sliding clamp
eventOf	[Pathway:R-SCR-9675815] Leading strand synthesis - Secale cereale
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Reaction:R-SCR-9675780] Dissociation of RFC after sliding clamp formation - Secale cereale
inferredFrom	[Reaction:R-OSA-9675801] Formation of sliding clamp - Oryza sativa
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [Complex:R-SCR-9675825] PCNA homotrimer [nucleoplasm] [Complex:R-SCR-9675873] RFC heteropentamer:RNA primer:DNA primer:origin duplex [nucleoplasm]
isInDisease	false
isInferred	true
name	Formation of sliding clamp
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [Complex:R-SCR-9675884] RFC heteropentamer:RNA primer:DNA primer:origin duplex:PCNA homotrimer [nucleoplasm]
precedingEvent	[Reaction:R-SCR-9675841] Binding of RFC - Secale cereale
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9823417] Secale cereale
stId	R-SCR-9675801
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

Referrals

(hasEvent)	[Pathway:R-SCR-9675815] Leading strand synthesis - Secale cereale
(precedingEvent)	[Reaction:R-SCR-9675780] Dissociation of RFC after sliding clamp formation - Secale cereale
(inferredTo)	[Reaction:R-OSA-9675801] Formation of sliding clamp - Oryza sativa

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