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4-alpha-methyl zymosterol+NAD(P)H+O2->4alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O

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compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10036036] Elser, Justin, 2025-03-24
dbId	10038695
displayName	4-alpha-methyl zymosterol+NAD(P)H+O2->4alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O
eventOf	[Pathway:R-PAV-1119439] Cholesterol biosynthesis III (via desmosterol) - Prunus avium [Pathway:R-PAV-1119559] Cholesterol biosynthesis I - Prunus avium
evidenceType	[EvidenceType:9939645] inferred by electronic annotation
followingEvent	[Reaction:R-PAV-1121309] 4alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O - Prunus avium
inferredFrom	[Reaction:R-OSA-1121120] 4-alpha-methyl zymosterol+NAD(P)H+O2->4alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O - Oryza sativa
input	[SimpleEntity:R-ALL-1131029] 4-alpha-methyl zymosterol [cytosol] [DefinedSet:R-ALL-428206] NAD(P)H [cytosol] [SimpleEntity:R-ALL-29368] O2 [cytosol]
isInDisease	false
isInferred	true
name	4-alpha-methyl zymosterol+NAD(P)H+O2->4alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O RXN66-315 biochemicalReaction85443
output	[SimpleEntity:R-ALL-1131017] 4alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [DefinedSet:R-ALL-428218] NAD(P)+ [cytosol]
releaseDate	2025-02-15
schemaClass	Reaction
species	[Species:9689230] Prunus avium
stId	R-PAV-1121120
summation	[Summation:9939644] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mappings from Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 1% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome.

Referrals

(hasEvent)	[Pathway:R-PAV-1119439] Cholesterol biosynthesis III (via desmosterol) - Prunus avium [Pathway:R-PAV-1119559] Cholesterol biosynthesis I - Prunus avium
(precedingEvent)	[Reaction:R-PAV-1121309] 4alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)H+O2->4alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O - Prunus avium
(inferredTo)	[Reaction:R-OSA-1121120] 4-alpha-methyl zymosterol+NAD(P)H+O2->4alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol+NAD(P)++H2O - Oryza sativa

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