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Loading of MCM2-7

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compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9640855] Gupta, Parul, 2019-04-03
dbId	9640880
displayName	Loading of MCM2-7
eventOf	[Pathway:R-OSA-9640882] Assembly of pre-replication complex - Oryza sativa
followingEvent	[Reaction:R-OSA-9675804] MCM2-7 mediated fork unwinding - Oryza sativa [Reaction:R-OSA-9645996] Displacement of CDC6 from pre-replication complex - Oryza sativa
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [Complex:R-OSA-9640874] MCM2-7 [nucleoplasm] [Complex:R-OSA-9640876] ORC:origin:CDT1:Cdc6 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9640764] The plant cell cycle: Pre-Replication complex formation and controls [LiteratureReference:1600739] Genome-wide Analysis of the Core DNA Replication Machinery in the Higher Plants Arabidopsis and Oryza sativa
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	Loading of MCM2-7
orthologousEvent	[Reaction:R-AIP-9640880] Loading of MCM2-7 - Arachis ipaensis [Reaction:R-ONI-9640880] Loading of MCM2-7 - Oryza nivara [Reaction:R-MGU-9640880] Loading of MCM2-7 - Erythranthe guttata [Reaction:R-SHI-9640880] Loading of MCM2-7 - Salvia hispanica [Reaction:R-TSP-9640880] Loading of MCM2-7 - Triticum spelta subsp. spelta [Reaction:R-LPR-9640880] Loading of MCM2-7 - Lolium perenne [Reaction:R-CLA-9640880] Loading of MCM2-7 - Citrullus lanatus [Reaction:R-ADU-9640880] Loading of MCM2-7 - Arachis duranensis [Reaction:R-PDA-9640880] Loading of MCM2-7 - Phoenix dactylifera [Reaction:R-OPU-9640880] Loading of MCM2-7 - Oryza punctata [Reaction:R-TDI-9640880] Loading of MCM2-7 - Triticum dicoccoides [Reaction:R-TTU-9640880] Loading of MCM2-7 - Triticum turgidum [Reaction:R-HLH-9640880] Loading of MCM2-7 - Humulus lupulus [Reaction:R-MAC-9640880] Loading of MCM2-7 - Musa acuminata [Reaction:R-OSI-9640880] Loading of MCM2-7 - Oryza sativa Indica Group [Reaction:R-SCR-9640880] Loading of MCM2-7 - Secale cereale [Reaction:R-CAR-9640880] Loading of MCM2-7 - Cicer arietinum [Reaction:R-AOF-9640880] Loading of MCM2-7 - Asparagus officinalis [Reaction:R-OGU-9640880] Loading of MCM2-7 - Oryza glumaepatula [Reaction:R-PED-9640880] Loading of MCM2-7 - Phyllostachys edulis [Reaction:R-CSI-9640880] Loading of MCM2-7 - Citrus sinensis [Reaction:R-ACO-9640880] Loading of MCM2-7 - Ananas comosus [Reaction:R-FVE-9640880] Loading of MCM2-7 - Fragaria vesca [Reaction:R-PTA-9640880] Loading of MCM2-7 - Pinus taeda [Reaction:R-JCU-9640880] Loading of MCM2-7 - Jatropha curcas [Reaction:R-SSP-9640880] Loading of MCM2-7 - Saccharum spontaneum [Reaction:R-AUM-9640880] Loading of MCM2-7 - Aegilops umbellulata [Reaction:R-ETE-9640880] Loading of MCM2-7 - Eragrostis tef [Reaction:R-ECG-9640880] Loading of MCM2-7 - Echinochloa crus-galli [Reaction:R-NNU-9640880] Loading of MCM2-7 - Nelumbo nucifera [Reaction:R-CSK-9640880] Loading of MCM2-7 - Cannabis sativa subsp. indica [Reaction:R-OBR-9640880] Loading of MCM2-7 - Oryza brachyantha [Reaction:R-LPE-9640880] Loading of MCM2-7 - Leersia perrieri [Reaction:R-TAE-9640880] Loading of MCM2-7 - Triticum aestivum [Reaction:R-PHA-9640880] Loading of MCM2-7 - Panicum hallii ("FIL2") [Reaction:R-OBA-9640880] Loading of MCM2-7 - Oryza barthii [Reaction:R-ZMY-9640880] Loading of MCM2-7 - Zea mays ver5 [Reaction:R-HLP-9640880] Loading of MCM2-7 - Humulus lupulus var. lupulus [Reaction:R-SVI-9640880] Loading of MCM2-7 - Setaria viridis [Reaction:R-NCO-9640880] Loading of MCM2-7 - Nymphaea colorata [Reaction:R-CRU-9640880] Loading of MCM2-7 - Capsella rubella [Reaction:R-COL-9640880] Loading of MCM2-7 - Corchorus olitorius [Reaction:R-TTI-9640880] Loading of MCM2-7 - Triticum timopheevii subsp. timopheevii [Reaction:R-OLO-9640880] Loading of MCM2-7 - Oryza longistaminata [Reaction:R-PAB-9640880] Loading of MCM2-7 - Picea abies [Reaction:R-ORU-9640880] Loading of MCM2-7 - Oryza rufipogon [Reaction:R-BDI-9640880] Loading of MCM2-7 - Brachypodium distachyon [Reaction:R-SBI-9640880] Loading of MCM2-7 - Sorghum bicolor [Reaction:R-OGL-9640880] Loading of MCM2-7 - Oryza glaberrima [Reaction:R-ASA-9640880] Loading of MCM2-7 - Avena sativa [Reaction:R-ATA-9640880] Loading of MCM2-7 - Aegilops tauschii [Reaction:R-TUR-9640880] Loading of MCM2-7 - Triticum urartu [Reaction:R-ECU-9640880] Loading of MCM2-7 - Eragrostis curvula [Reaction:R-PHH-9640880] Loading of MCM2-7 - Panicum hallii var. hallii ("HAL2") [Reaction:R-ZMA-9640880] Loading of MCM2-7 - Zea mays [Reaction:R-OME-9640880] Loading of MCM2-7 - Oryza meridionalis [Reaction:R-DEX-9640880] Loading of MCM2-7 - Digitaria exilis [Reaction:R-SIT-9640880] Loading of MCM2-7 - Setaria italica
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [DefinedSet:R-OSA-9640871] CDT1 [nucleoplasm] [Complex:R-OSA-9640877] Pre-RC [nucleoplasm]
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-9640880
summation	[Summation:9640868] CDC6 and CDT1 proteins act synergistically to load the MCM2-...

Referrals

(hasEvent)	[Pathway:R-OSA-9640882] Assembly of pre-replication complex - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-9675804] MCM2-7 mediated fork unwinding - Oryza sativa [Reaction:R-OSA-9645996] Displacement of CDC6 from pre-replication complex - Oryza sativa

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