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phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP

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authored	[InstanceEdit:8853982] Gupta, Parul, 2015-11-20
catalystActivity	[CatalystActivity:8853996] cardiolipin synthase activity of cardiolipin synthase [mitochondrial inner membrane]
compartment	[Compartment:70616] mitochondrial inner membrane
created	[InstanceEdit:8854000] Gupta, Parul, 2016-01-25
dbId	8853975
displayName	phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP
eventOf	[Pathway:R-OSA-1119260] Cardiolipin biosynthesis - Oryza sativa
input	[SimpleEntity:R-ALL-1524064] CDP-DAG [mitochondrial inner membrane] [SimpleEntity:R-ALL-8853999] L-1-phosphatidyl-glycerol [mitochondrial inner membrane]
isChimeric	false
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP Cardiolipin synthase
orthologousEvent	[Reaction:R-VUN-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Vigna unguiculata [Reaction:R-MPO-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Marchantia polymorpha [Reaction:R-OOF-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Oryza officinalis [Reaction:R-STU-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Solanum tuberosum [Reaction:R-NCO-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Nymphaea colorata [Reaction:R-CCA-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Cajanus cajan [Reaction:R-PSO-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Papaver somniferum [Reaction:R-CQI-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Chenopodium quinoa [Reaction:R-OMI-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Oryza minuta [Reaction:R-ACH-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Actinidia chinensis [Reaction:R-PTI-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Populus trichocarpa [Reaction:R-VRA-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Vigna radiata [Reaction:R-CRE-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Chlamydomonas reinhardtii [Reaction:R-TCA-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Theobroma cacao [Reaction:R-ITR-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Ipomoea triloba [Reaction:R-LPR-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Lolium perenne [Reaction:R-OBA-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Oryza barthii [Reaction:R-NAT-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Nicotiana attenuata [Reaction:R-MDO-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Malus domestica [Reaction:R-CCD-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Cynara cardunculus var. scolymus [Reaction:R-TAE-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Triticum aestivum [Reaction:R-ETE-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Eragrostis tef [Reaction:R-OGL-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Oryza glaberrima [Reaction:R-CSK-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Cannabis sativa subsp. indica [Reaction:R-CML-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Cucumis melo [Reaction:R-PVU-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Phaseolus vulgaris [Reaction:R-CSA-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Cucumis sativus [Reaction:R-FVE-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Fragaria vesca [Reaction:R-AHA-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Arabidopsis halleri [Reaction:R-PPA-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Physcomitrella patens [Reaction:R-DRO-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Dioscorea rotundata [Reaction:R-CAR-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Cicer arietinum [Reaction:R-HAN-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Helianthus annuus [Reaction:R-NNU-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Nelumbo nucifera [Reaction:R-MGU-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Erythranthe guttata [Reaction:R-AHY-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Arachis hypogaea [Reaction:R-ECG-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Echinochloa crus-galli [Reaction:R-SHI-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Salvia hispanica [Reaction:R-CSC-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Cannabis sativa [Reaction:R-SVI-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Setaria viridis [Reaction:R-CCL-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Citrus clementina [Reaction:R-ECU-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Eragrostis curvula [Reaction:R-CCN-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Coffea canephora [Reaction:R-TPR-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Trifolium pratense [Reaction:R-SIT-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Setaria italica [Reaction:R-PHA-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Panicum hallii ("FIL2") [Reaction:R-PTA-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Pinus taeda [Reaction:R-RCH-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Rosa chinensis [Reaction:R-ACO-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Ananas comosus [Reaction:R-SLY-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Solanum lycopersicum [Reaction:R-TDI-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Triticum dicoccoides [Reaction:R-QLO-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Quercus lobata [Reaction:R-MAC-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Musa acuminata [Reaction:R-ZMY-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Zea mays ver5 [Reaction:R-ADU-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Arachis duranensis [Reaction:R-PHH-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Panicum hallii var. hallii ("HAL2") [Reaction:R-AOF-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Asparagus officinalis [Reaction:R-VAN-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Vigna angularis [Reaction:R-FCR-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Ficus carica [Reaction:R-CSI-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Citrus sinensis [Reaction:R-HLP-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Humulus lupulus var. lupulus [Reaction:R-AIP-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Arachis ipaensis [Reaction:R-JCU-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Jatropha curcas [Reaction:R-MES-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Manihot esculenta [Reaction:R-ATR-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Amborella trichopoda [Reaction:R-EGR-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Eucalyptus grandis [Reaction:R-PPE-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Prunus persica [Reaction:R-DCA-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Daucus carota [Reaction:R-BNA-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Brassica napus [Reaction:R-PVE-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Pistacia vera [Reaction:R-GRA-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Gossypium raimondii [Reaction:R-JRE-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Juglans regia [Reaction:R-BVU-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Beta vulgaris [Reaction:R-CAN-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Capsicum annuum [Reaction:R-GSO-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Glycine soja [Reaction:R-SMO-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Selaginella moellendorffii [Reaction:R-DEX-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Digitaria exilis [Reaction:R-ZMA-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Zea mays [Reaction:R-ORU-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Oryza rufipogon [Reaction:R-OES-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Olea europaea var. sylvestris [Reaction:R-TSP-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Triticum spelta subsp. spelta [Reaction:R-OAU-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Oryza australiensis [Reaction:R-MTR-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Medicago truncatula [Reaction:R-BOL-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Brassica oleracea [Reaction:R-BJU-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Brassica juncea [Reaction:R-LSA-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Lactuca sativa [Reaction:R-COL-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Corchorus olitorius [Reaction:R-HVU-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Hordeum vulgare [Reaction:R-ALY-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Arabidopsis lyrata [Reaction:R-VVN-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Vitis vinifera [Reaction:R-SCR-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Secale cereale [Reaction:R-OSI-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Oryza sativa Indica Group [Reaction:R-LST-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Lathyrus sativus [Reaction:R-ASA-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Avena sativa [Reaction:R-FEX-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Fraxinus excelsior (European ash) [Reaction:R-PAB-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Picea abies [Reaction:R-OEU-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Olea europaea [Reaction:R-TTI-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Triticum timopheevii subsp. timopheevii [Reaction:R-CCI-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Corymbia citriodora [Reaction:R-PAV-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Prunus avium [Reaction:R-PSA-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Pisum sativum [Reaction:R-CRU-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Capsella rubella [Reaction:R-VFA-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Vicia faba var. faba [Reaction:R-CCP-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Corchorus capsularis [Reaction:R-CLA-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Citrullus lanatus [Reaction:R-SSP-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Saccharum spontaneum [Reaction:R-SBI-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Sorghum bicolor [Reaction:R-ATH-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Arabidopsis thaliana [Reaction:R-OLU-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Ostreococcus lucimarinus [Reaction:R-SPC-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Synechocystis sp. PCC 6803 [Reaction:R-BDI-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Brachypodium distachyon [Reaction:R-AUM-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Aegilops umbellulata [Reaction:R-GMA-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Glycine max [Reaction:R-OGR-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Oryza meyeriana var. granulata [Reaction:R-BRA-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Brassica rapa [Reaction:R-ATA-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Aegilops tauschii [Reaction:R-CST-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Camelina sativa [Reaction:R-LAN-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Lupinus angustifolius [Reaction:R-TTU-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Triticum turgidum [Reaction:R-SIN-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Sesamum indicum [Reaction:R-ZJA-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Zoysia japonica [Reaction:R-QSU-8853975] phosphatidyl-glycerol+CDP-diacylglycerol-->Cardiolipin+CMP - Quercus suber
output	[SimpleEntity:R-ALL-1524072] cardiolipin [mitochondrial inner membrane] [SimpleEntity:R-ALL-1524067] CMP [mitochondrial matrix]
precedingEvent	[Reaction:R-OSA-1119840] phosphatidylglycerol-phosphate+H2O-->phosphatidyl-glycerol+phosphate - Oryza sativa
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-8853975
summation	[Summation:8853989] Biosynthesis of CDP-DAG is catalyzed by phosphatidate cytid...

Referrals

(hasEvent)

[Pathway:R-OSA-1119260] Cardiolipin biosynthesis - Oryza sativa