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dihydroxy-acid dehydratase

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catalystActivity	[CatalystActivity:1118131] dihydroxy-acid dehydratase activity of dihydroxy-acid dehydratase (LOC_OS08G44530.1) [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:27969] EC:4.2.1.9 [DatabaseIdentifier:1138115] RiceCyc:DIHYDROXYMETVALDEHYDRAT-RXN
dbId	1121465
displayName	dihydroxy-acid dehydratase
eventOf	[Pathway:R-OSA-1119460] Isoleucine biosynthesis from threonine - Oryza sativa
followingEvent	[Reaction:R-OSA-1120563] branched-chain amino acid aminotransferase - Oryza sativa
input	[SimpleEntity:R-ALL-1130563] 2,3-dihydroxy-3-methylvalerate [cytosol]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	dihydroxy-acid dehydratase biochemicalReaction12350
orthologousEvent	[Reaction:R-QLO-1121465] dihydroxy-acid dehydratase - Quercus lobata [Reaction:R-ACO-1121465] dihydroxy-acid dehydratase - Ananas comosus [Reaction:R-DEX-1121465] dihydroxy-acid dehydratase - Digitaria exilis [Reaction:R-PSA-1121465] dihydroxy-acid dehydratase - Pisum sativum [Reaction:R-TSP-1121465] dihydroxy-acid dehydratase - Triticum spelta subsp. spelta [Reaction:R-OSI-1121465] dihydroxy-acid dehydratase - Oryza sativa Indica Group [Reaction:R-OLO-1121465] dihydroxy-acid dehydratase - Oryza longistaminata [Reaction:R-LSA-1121465] dihydroxy-acid dehydratase - Lactuca sativa [Reaction:R-MAC-1121465] dihydroxy-acid dehydratase - Musa acuminata [Reaction:R-MPO-1121465] dihydroxy-acid dehydratase - Marchantia polymorpha [Reaction:R-CBA-1121465] dihydroxy-acid dehydratase - Chara braunii [Reaction:R-LAN-1121465] dihydroxy-acid dehydratase - Lupinus angustifolius [Reaction:R-QSU-1121465] dihydroxy-acid dehydratase - Quercus suber [Reaction:R-CCR-1121465] dihydroxy-acid dehydratase - Chondrus crispus [Reaction:R-HVU-1121465] dihydroxy-acid dehydratase - Hordeum vulgare [Reaction:R-OGL-1121465] dihydroxy-acid dehydratase - Oryza glaberrima [Reaction:R-LST-1121465] dihydroxy-acid dehydratase - Lathyrus sativus [Reaction:R-NCO-1121465] dihydroxy-acid dehydratase - Nymphaea colorata [Reaction:R-VAN-1121465] dihydroxy-acid dehydratase - Vigna angularis [Reaction:R-CCP-1121465] dihydroxy-acid dehydratase - Corchorus capsularis [Reaction:R-OGR-1121465] dihydroxy-acid dehydratase - Oryza meyeriana var. granulata [Reaction:R-PVE-1121465] dihydroxy-acid dehydratase - Pistacia vera [Reaction:R-FEX-1121465] dihydroxy-acid dehydratase - Fraxinus excelsior (European ash) [Reaction:R-CSA-1121465] dihydroxy-acid dehydratase - Cucumis sativus [Reaction:R-AUM-1121465] dihydroxy-acid dehydratase - Aegilops umbellulata [Reaction:R-SMO-1121465] dihydroxy-acid dehydratase - Selaginella moellendorffii [Reaction:R-BNA-1121465] dihydroxy-acid dehydratase - Brassica napus [Reaction:R-STU-1121465] dihydroxy-acid dehydratase - Solanum tuberosum [Reaction:R-AHY-1121465] dihydroxy-acid dehydratase - Arachis hypogaea [Reaction:R-CAR-1121465] dihydroxy-acid dehydratase - Cicer arietinum [Reaction:R-ORU-1121465] dihydroxy-acid dehydratase - Oryza rufipogon [Reaction:R-ADU-1121465] dihydroxy-acid dehydratase - Arachis duranensis [Reaction:R-ETE-1121465] dihydroxy-acid dehydratase - Eragrostis tef [Reaction:R-VRA-1121465] dihydroxy-acid dehydratase - Vigna radiata [Reaction:R-TTI-1121465] dihydroxy-acid dehydratase - Triticum timopheevii subsp. timopheevii [Reaction:R-ALY-1121465] dihydroxy-acid dehydratase - Arabidopsis lyrata [Reaction:R-TTU-1121465] dihydroxy-acid dehydratase - Triticum turgidum [Reaction:R-VUN-1121465] dihydroxy-acid dehydratase - Vigna unguiculata [Reaction:R-CST-1121465] dihydroxy-acid dehydratase - Camelina sativa [Reaction:R-BOL-1121465] dihydroxy-acid dehydratase - Brassica oleracea [Reaction:R-PPE-1121465] dihydroxy-acid dehydratase - Prunus persica [Reaction:R-PSO-1121465] dihydroxy-acid dehydratase - Papaver somniferum [Reaction:R-ECG-1121465] dihydroxy-acid dehydratase - Echinochloa crus-galli [Reaction:R-OLU-1121465] dihydroxy-acid dehydratase - Ostreococcus lucimarinus [Reaction:R-SBI-1121465] dihydroxy-acid dehydratase - Sorghum bicolor [Reaction:R-PHH-1121465] dihydroxy-acid dehydratase - Panicum hallii var. hallii ("HAL2") [Reaction:R-BJU-1121465] dihydroxy-acid dehydratase - Brassica juncea [Reaction:R-FVE-1121465] dihydroxy-acid dehydratase - Fragaria vesca [Reaction:R-CML-1121465] dihydroxy-acid dehydratase - Cucumis melo [Reaction:R-MES-1121465] dihydroxy-acid dehydratase - Manihot esculenta [Reaction:R-FCR-1121465] dihydroxy-acid dehydratase - Ficus carica [Reaction:R-ZMA-1121465] dihydroxy-acid dehydratase - Zea mays [Reaction:R-SPC-1121465] dihydroxy-acid dehydratase - Synechocystis sp. PCC 6803 [Reaction:R-OES-1121465] dihydroxy-acid dehydratase - Olea europaea var. sylvestris [Reaction:R-JRE-1121465] dihydroxy-acid dehydratase - Juglans regia [Reaction:R-TCA-1121465] dihydroxy-acid dehydratase - Theobroma cacao [Reaction:R-CQI-1121465] dihydroxy-acid dehydratase - Chenopodium quinoa [Reaction:R-ATR-1121465] dihydroxy-acid dehydratase - Amborella trichopoda [Reaction:R-JCU-1121465] dihydroxy-acid dehydratase - Jatropha curcas [Reaction:R-PAV-1121465] dihydroxy-acid dehydratase - Prunus avium [Reaction:R-PVU-1121465] dihydroxy-acid dehydratase - Phaseolus vulgaris [Reaction:R-OMI-1121465] dihydroxy-acid dehydratase - Oryza minuta [Reaction:R-NAT-1121465] dihydroxy-acid dehydratase - Nicotiana attenuata [Reaction:R-PTI-1121465] dihydroxy-acid dehydratase - Populus trichocarpa [Reaction:R-DCA-1121465] dihydroxy-acid dehydratase - Daucus carota [Reaction:R-GSO-1121465] dihydroxy-acid dehydratase - Glycine soja [Reaction:R-OPU-1121465] dihydroxy-acid dehydratase - Oryza punctata [Reaction:R-OEU-1121465] dihydroxy-acid dehydratase - Olea europaea [Reaction:R-OOF-1121465] dihydroxy-acid dehydratase - Oryza officinalis [Reaction:R-ATA-1121465] dihydroxy-acid dehydratase - Aegilops tauschii [Reaction:R-MDO-1121465] dihydroxy-acid dehydratase - Malus domestica [Reaction:R-OAU-1121465] dihydroxy-acid dehydratase - Oryza australiensis [Reaction:R-OBA-1121465] dihydroxy-acid dehydratase - Oryza barthii [Reaction:R-TAE-1121465] dihydroxy-acid dehydratase - Triticum aestivum [Reaction:R-SSP-1121465] dihydroxy-acid dehydratase - Saccharum spontaneum [Reaction:R-CME-1121465] dihydroxy-acid dehydratase - Cyanidioschyzon merolae [Reaction:R-BVU-1121465] dihydroxy-acid dehydratase - Beta vulgaris [Reaction:R-RCH-1121465] dihydroxy-acid dehydratase - Rosa chinensis [Reaction:R-BDI-1121465] dihydroxy-acid dehydratase - Brachypodium distachyon [Reaction:R-PTA-1121465] dihydroxy-acid dehydratase - Pinus taeda [Reaction:R-SCR-1121465] dihydroxy-acid dehydratase - Secale cereale [Reaction:R-SLY-1121465] dihydroxy-acid dehydratase - Solanum lycopersicum [Reaction:R-HAN-1121465] dihydroxy-acid dehydratase - Helianthus annuus [Reaction:R-VVN-1121465] dihydroxy-acid dehydratase - Vitis vinifera [Reaction:R-ITR-1121465] dihydroxy-acid dehydratase - Ipomoea triloba [Reaction:R-PED-1121465] dihydroxy-acid dehydratase - Phyllostachys edulis [Reaction:R-CCD-1121465] dihydroxy-acid dehydratase - Cynara cardunculus var. scolymus [Reaction:R-CCN-1121465] dihydroxy-acid dehydratase - Coffea canephora [Reaction:R-GMA-1121465] dihydroxy-acid dehydratase - Glycine max [Reaction:R-ECU-1121465] dihydroxy-acid dehydratase - Eragrostis curvula [Reaction:R-CAN-1121465] dihydroxy-acid dehydratase - Capsicum annuum [Reaction:R-VFA-1121465] dihydroxy-acid dehydratase - Vicia faba var. faba [Reaction:R-BRA-1121465] dihydroxy-acid dehydratase - Brassica rapa [Reaction:R-ONI-1121465] dihydroxy-acid dehydratase - Oryza nivara [Reaction:R-AOF-1121465] dihydroxy-acid dehydratase - Asparagus officinalis [Reaction:R-PPA-1121465] dihydroxy-acid dehydratase - Physcomitrella patens [Reaction:R-TDI-1121465] dihydroxy-acid dehydratase - Triticum dicoccoides [Reaction:R-CCL-1121465] dihydroxy-acid dehydratase - Citrus clementina [Reaction:R-CCA-1121465] dihydroxy-acid dehydratase - Cajanus cajan [Reaction:R-SVI-1121465] dihydroxy-acid dehydratase - Setaria viridis [Reaction:R-OBR-1121465] dihydroxy-acid dehydratase - Oryza brachyantha [Reaction:R-DRO-1121465] dihydroxy-acid dehydratase - Dioscorea rotundata [Reaction:R-PAB-1121465] dihydroxy-acid dehydratase - Picea abies [Reaction:R-ATH-1121465] dihydroxy-acid dehydratase - Arabidopsis thaliana [Reaction:R-COL-1121465] dihydroxy-acid dehydratase - Corchorus olitorius [Reaction:R-CRE-1121465] dihydroxy-acid dehydratase - Chlamydomonas reinhardtii [Reaction:R-CSK-1121465] dihydroxy-acid dehydratase - Cannabis sativa subsp. indica [Reaction:R-GSU-1121465] dihydroxy-acid dehydratase - Galdieria sulphuraria [Reaction:R-CCI-1121465] dihydroxy-acid dehydratase - Corymbia citriodora [Reaction:R-HLP-1121465] dihydroxy-acid dehydratase - Humulus lupulus var. lupulus [Reaction:R-OGU-1121465] dihydroxy-acid dehydratase - Oryza glumaepatula [Reaction:R-NNU-1121465] dihydroxy-acid dehydratase - Nelumbo nucifera [Reaction:R-TUR-1121465] dihydroxy-acid dehydratase - Triticum urartu [Reaction:R-AHA-1121465] dihydroxy-acid dehydratase - Arabidopsis halleri [Reaction:R-SHI-1121465] dihydroxy-acid dehydratase - Salvia hispanica [Reaction:R-AIP-1121465] dihydroxy-acid dehydratase - Arachis ipaensis [Reaction:R-ASA-1121465] dihydroxy-acid dehydratase - Avena sativa [Reaction:R-ACH-1121465] dihydroxy-acid dehydratase - Actinidia chinensis [Reaction:R-CSC-1121465] dihydroxy-acid dehydratase - Cannabis sativa [Reaction:R-ZMY-1121465] dihydroxy-acid dehydratase - Zea mays ver5 [Reaction:R-PHA-1121465] dihydroxy-acid dehydratase - Panicum hallii ("FIL2") [Reaction:R-MGU-1121465] dihydroxy-acid dehydratase - Erythranthe guttata [Reaction:R-SIN-1121465] dihydroxy-acid dehydratase - Sesamum indicum [Reaction:R-ZJA-1121465] dihydroxy-acid dehydratase - Zoysia japonica [Reaction:R-SIT-1121465] dihydroxy-acid dehydratase - Setaria italica [Reaction:R-MTR-1121465] dihydroxy-acid dehydratase - Medicago truncatula [Reaction:R-LPE-1121465] dihydroxy-acid dehydratase - Leersia perrieri [Reaction:R-CLA-1121465] dihydroxy-acid dehydratase - Citrullus lanatus [Reaction:R-CSI-1121465] dihydroxy-acid dehydratase - Citrus sinensis [Reaction:R-GRA-1121465] dihydroxy-acid dehydratase - Gossypium raimondii [Reaction:R-TPR-1121465] dihydroxy-acid dehydratase - Trifolium pratense [Reaction:R-CRU-1121465] dihydroxy-acid dehydratase - Capsella rubella [Reaction:R-PDA-1121465] dihydroxy-acid dehydratase - Phoenix dactylifera [Reaction:R-EGR-1121465] dihydroxy-acid dehydratase - Eucalyptus grandis [Reaction:R-OKA-1121465] dihydroxy-acid dehydratase - Oryza sativa aus subgroup
output	[SimpleEntity:R-ALL-1130975] 2-keto-3-methyl-valerate [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
precedingEvent	[Reaction:R-OSA-1120842] ketol-acid reductoisomerase - Oryza sativa
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1121465
summation	[Summation:2851318] 2,3-dihydroxy-3-methylvalerate is converted to 2-keto-3-meth...

Referrals

(hasEvent)	[Pathway:R-OSA-1119460] Isoleucine biosynthesis from threonine - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-1120563] branched-chain amino acid aminotransferase - Oryza sativa