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Imidazoleglycerol phosphate synthase

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catalystActivity	[CatalystActivity:1119216] pentosyltransferase activity of 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (LOC_OS05G33260.1) [plastid stroma]
compartment	[Compartment:1141] plastid stroma
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:1154476] EC-NUMBER:2.4.2.- [DatabaseIdentifier:1142715] RiceCyc:GLUTAMIDOTRANS-RXN
dbId	1121446
displayName	Imidazoleglycerol phosphate synthase
eventOf	[Pathway:R-OSA-1119509] Histidine biosynthesis I - Oryza sativa
followingEvent	[Reaction:R-OSA-1120127] Imidazoleglycerol-phosphate dehydratase - Oryza sativa
input	[SimpleEntity:R-ALL-4755395] L-Gln [plastid stroma] [SimpleEntity:R-ALL-4755387] phosphoribulosylformimino-AICAR-P [plastid stroma]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11529250] Elser, Justin, 2025-03-27
name	Imidazoleglycerol phosphate synthase phosphoribulosylformimino-AICAR-P+L-glutamine->L-glutamate+D-erythro-imidazole-glycerol-phosphate+AICAR GLUTAMIDOTRANS-RXN biochemicalReaction63074
orthologousEvent	[Reaction:R-TUR-1121446] Imidazoleglycerol phosphate synthase - Triticum urartu [Reaction:R-OEU-1121446] Imidazoleglycerol phosphate synthase - Olea europaea [Reaction:R-LST-1121446] Imidazoleglycerol phosphate synthase - Lathyrus sativus [Reaction:R-TPR-1121446] Imidazoleglycerol phosphate synthase - Trifolium pratense [Reaction:R-ZMY-1121446] Imidazoleglycerol phosphate synthase - Zea mays ver5 [Reaction:R-CCN-1121446] Imidazoleglycerol phosphate synthase - Coffea canephora [Reaction:R-EGR-1121446] Imidazoleglycerol phosphate synthase - Eucalyptus grandis [Reaction:R-OLU-1121446] Imidazoleglycerol phosphate synthase - Ostreococcus lucimarinus [Reaction:R-OSI-1121446] Imidazoleglycerol phosphate synthase - Oryza sativa Indica Group [Reaction:R-MPO-1121446] Imidazoleglycerol phosphate synthase - Marchantia polymorpha [Reaction:R-NAT-1121446] Imidazoleglycerol phosphate synthase - Nicotiana attenuata [Reaction:R-NCO-1121446] Imidazoleglycerol phosphate synthase - Nymphaea colorata [Reaction:R-DCA-1121446] Imidazoleglycerol phosphate synthase - Daucus carota [Reaction:R-SMO-1121446] Imidazoleglycerol phosphate synthase - Selaginella moellendorffii [Reaction:R-CST-1121446] Imidazoleglycerol phosphate synthase - Camelina sativa [Reaction:R-ATH-1121446] Imidazoleglycerol phosphate synthase - Arabidopsis thaliana [Reaction:R-PAV-1121446] Imidazoleglycerol phosphate synthase - Prunus avium [Reaction:R-FCR-1121446] Imidazoleglycerol phosphate synthase - Ficus carica [Reaction:R-BVU-1121446] Imidazoleglycerol phosphate synthase - Beta vulgaris [Reaction:R-PSA-1121446] Imidazoleglycerol phosphate synthase - Pisum sativum [Reaction:R-LSA-1121446] Imidazoleglycerol phosphate synthase - Lactuca sativa [Reaction:R-MDO-1121446] Imidazoleglycerol phosphate synthase - Malus domestica [Reaction:R-ATR-1121446] Imidazoleglycerol phosphate synthase - Amborella trichopoda [Reaction:R-SLY-1121446] Imidazoleglycerol phosphate synthase - Solanum lycopersicum [Reaction:R-MTR-1121446] Imidazoleglycerol phosphate synthase - Medicago truncatula [Reaction:R-CQI-1121446] Imidazoleglycerol phosphate synthase - Chenopodium quinoa [Reaction:R-CCP-1121446] Imidazoleglycerol phosphate synthase - Corchorus capsularis [Reaction:R-OGL-1121446] Imidazoleglycerol phosphate synthase - Oryza glaberrima [Reaction:R-VUN-1121446] Imidazoleglycerol phosphate synthase - Vigna unguiculata [Reaction:R-SBI-1121446] Imidazoleglycerol phosphate synthase - Sorghum bicolor [Reaction:R-PVU-1121446] Imidazoleglycerol phosphate synthase - Phaseolus vulgaris [Reaction:R-BOL-1121446] Imidazoleglycerol phosphate synthase - Brassica oleracea [Reaction:R-QLO-1121446] Imidazoleglycerol phosphate synthase - Quercus lobata [Reaction:R-VFA-1121446] Imidazoleglycerol phosphate synthase - Vicia faba var. faba [Reaction:R-CCL-1121446] Imidazoleglycerol phosphate synthase - Citrus clementina [Reaction:R-GMA-1121446] Imidazoleglycerol phosphate synthase - Glycine max [Reaction:R-RCH-1121446] Imidazoleglycerol phosphate synthase - Rosa chinensis [Reaction:R-SCR-1121446] Imidazoleglycerol phosphate synthase - Secale cereale [Reaction:R-TTI-1121446] Imidazoleglycerol phosphate synthase - Triticum timopheevii subsp. timopheevii [Reaction:R-VVN-1121446] Imidazoleglycerol phosphate synthase - Vitis vinifera [Reaction:R-CCI-1121446] Imidazoleglycerol phosphate synthase - Corymbia citriodora [Reaction:R-TDI-1121446] Imidazoleglycerol phosphate synthase - Triticum dicoccoides [Reaction:R-CAN-1121446] Imidazoleglycerol phosphate synthase - Capsicum annuum [Reaction:R-FEX-1121446] Imidazoleglycerol phosphate synthase - Fraxinus excelsior (European ash) [Reaction:R-VRA-1121446] Imidazoleglycerol phosphate synthase - Vigna radiata [Reaction:R-HAN-1121446] Imidazoleglycerol phosphate synthase - Helianthus annuus [Reaction:R-GSO-1121446] Imidazoleglycerol phosphate synthase - Glycine soja [Reaction:R-PSO-1121446] Imidazoleglycerol phosphate synthase - Papaver somniferum [Reaction:R-STU-1121446] Imidazoleglycerol phosphate synthase - Solanum tuberosum [Reaction:R-ECU-1121446] Imidazoleglycerol phosphate synthase - Eragrostis curvula [Reaction:R-AHY-1121446] Imidazoleglycerol phosphate synthase - Arachis hypogaea [Reaction:R-TAE-1121446] Imidazoleglycerol phosphate synthase - Triticum aestivum [Reaction:R-HVU-1121446] Imidazoleglycerol phosphate synthase - Hordeum vulgare [Reaction:R-DEX-1121446] Imidazoleglycerol phosphate synthase - Digitaria exilis [Reaction:R-CSA-1121446] Imidazoleglycerol phosphate synthase - Cucumis sativus [Reaction:R-CCD-1121446] Imidazoleglycerol phosphate synthase - Cynara cardunculus var. scolymus [Reaction:R-ETE-1121446] Imidazoleglycerol phosphate synthase - Eragrostis tef [Reaction:R-CRE-1121446] Imidazoleglycerol phosphate synthase - Chlamydomonas reinhardtii [Reaction:R-BJU-1121446] Imidazoleglycerol phosphate synthase - Brassica juncea [Reaction:R-BRA-1121446] Imidazoleglycerol phosphate synthase - Brassica rapa [Reaction:R-OES-1121446] Imidazoleglycerol phosphate synthase - Olea europaea var. sylvestris [Reaction:R-OBA-1121446] Imidazoleglycerol phosphate synthase - Oryza barthii [Reaction:R-PHA-1121446] Imidazoleglycerol phosphate synthase - Panicum hallii ("FIL2") [Reaction:R-LPR-1121446] Imidazoleglycerol phosphate synthase - Lolium perenne [Reaction:R-PPE-1121446] Imidazoleglycerol phosphate synthase - Prunus persica [Reaction:R-PVE-1121446] Imidazoleglycerol phosphate synthase - Pistacia vera [Reaction:R-ALY-1121446] Imidazoleglycerol phosphate synthase - Arabidopsis lyrata [Reaction:R-VAN-1121446] Imidazoleglycerol phosphate synthase - Vigna angularis [Reaction:R-CSC-1121446] Imidazoleglycerol phosphate synthase - Cannabis sativa [Reaction:R-MES-1121446] Imidazoleglycerol phosphate synthase - Manihot esculenta [Reaction:R-SIN-1121446] Imidazoleglycerol phosphate synthase - Sesamum indicum [Reaction:R-SSP-1121446] Imidazoleglycerol phosphate synthase - Saccharum spontaneum [Reaction:R-ASA-1121446] Imidazoleglycerol phosphate synthase - Avena sativa [Reaction:R-TCA-1121446] Imidazoleglycerol phosphate synthase - Theobroma cacao [Reaction:R-TSP-1121446] Imidazoleglycerol phosphate synthase - Triticum spelta subsp. spelta [Reaction:R-TTU-1121446] Imidazoleglycerol phosphate synthase - Triticum turgidum [Reaction:R-CCA-1121446] Imidazoleglycerol phosphate synthase - Cajanus cajan [Reaction:R-PPA-1121446] Imidazoleglycerol phosphate synthase - Physcomitrella patens [Reaction:R-PTI-1121446] Imidazoleglycerol phosphate synthase - Populus trichocarpa [Reaction:R-ONI-1121446] Imidazoleglycerol phosphate synthase - Oryza nivara [Reaction:R-SVI-1121446] Imidazoleglycerol phosphate synthase - Setaria viridis [Reaction:R-BNA-1121446] Imidazoleglycerol phosphate synthase - Brassica napus [Reaction:R-PHH-1121446] Imidazoleglycerol phosphate synthase - Panicum hallii var. hallii ("HAL2") [Reaction:R-SIT-1121446] Imidazoleglycerol phosphate synthase - Setaria italica [Reaction:R-AHA-1121446] Imidazoleglycerol phosphate synthase - Arabidopsis halleri [Reaction:R-ACH-1121446] Imidazoleglycerol phosphate synthase - Actinidia chinensis [Reaction:R-GRA-1121446] Imidazoleglycerol phosphate synthase - Gossypium raimondii [Reaction:R-BDI-1121446] Imidazoleglycerol phosphate synthase - Brachypodium distachyon [Reaction:R-JRE-1121446] Imidazoleglycerol phosphate synthase - Juglans regia [Reaction:R-ECG-1121446] Imidazoleglycerol phosphate synthase - Echinochloa crus-galli [Reaction:R-CML-1121446] Imidazoleglycerol phosphate synthase - Cucumis melo
output	[SimpleEntity:R-ALL-4755388] AICAR [plastid stroma] [SimpleEntity:R-ALL-4755402] D-erythro-imidazole-glycerol-phosphate [plastid stroma] [SimpleEntity:R-ALL-4755396] L-Glu [plastid stroma]
precedingEvent	[Reaction:R-OSA-1120832] N-(5'-phospho-D-ribosylformimino)-5-amino-1-(5''-phosphoribosyl)-4- imidazole carboxamide isomerase - Oryza sativa
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1121446
summation	[Summation:4788613] Phosphoribulosylformimino-AICAR-P is converted to D-erythro-...

Referrals

(hasEvent)	[Pathway:R-OSA-1119509] Histidine biosynthesis I - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-1120127] Imidazoleglycerol-phosphate dehydratase - Oryza sativa