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Homogentisate 1,2-dioxygenase

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catalystActivity	[CatalystActivity:1118418] homogentisate 1,2-dioxygenase activity of homogentisate 1,2-dioxygenase [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:26640] EC:1.13.11.5 [DatabaseIdentifier:1137999] RiceCyc:HOMOGENTISATE-12-DIOXYGENASE-RXN
dbId	1121430
displayName	Homogentisate 1,2-dioxygenase
eventOf	[Pathway:R-OSA-1119506] tyrosine degradation I - Oryza sativa
followingEvent	[Reaction:R-OSA-1120380] Maleylacetoacetate isomerase - Oryza sativa
input	[SimpleEntity:R-ALL-30337] HGTA [cytosol] [SimpleEntity:R-ALL-29368] O2 [cytosol]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	Homogentisate 1,2-dioxygenase Homogentisic acid oxidase Homogentisate oxygenase Homogentisicase biochemicalReaction87691
orthologousEvent	[Reaction:R-QLO-1121430] Homogentisate 1,2-dioxygenase - Quercus lobata [Reaction:R-SSP-1121430] Homogentisate 1,2-dioxygenase - Saccharum spontaneum [Reaction:R-OGU-1121430] Homogentisate 1,2-dioxygenase - Oryza glumaepatula [Reaction:R-VVN-1121430] Homogentisate 1,2-dioxygenase - Vitis vinifera [Reaction:R-HAN-1121430] Homogentisate 1,2-dioxygenase - Helianthus annuus [Reaction:R-ECG-1121430] Homogentisate 1,2-dioxygenase - Echinochloa crus-galli [Reaction:R-CCL-1121430] Homogentisate 1,2-dioxygenase - Citrus clementina [Reaction:R-ZMA-1121430] Homogentisate 1,2-dioxygenase - Zea mays [Reaction:R-SIT-1121430] Homogentisate 1,2-dioxygenase - Setaria italica [Reaction:R-CAR-1121430] Homogentisate 1,2-dioxygenase - Cicer arietinum [Reaction:R-CSA-1121430] Homogentisate 1,2-dioxygenase - Cucumis sativus [Reaction:R-CST-1121430] Homogentisate 1,2-dioxygenase - Camelina sativa [Reaction:R-ATA-1121430] Homogentisate 1,2-dioxygenase - Aegilops tauschii [Reaction:R-PTA-1121430] Homogentisate 1,2-dioxygenase - Pinus taeda [Reaction:R-PVE-1121430] Homogentisate 1,2-dioxygenase - Pistacia vera [Reaction:R-OES-1121430] Homogentisate 1,2-dioxygenase - Olea europaea var. sylvestris [Reaction:R-ETE-1121430] Homogentisate 1,2-dioxygenase - Eragrostis tef [Reaction:R-VAN-1121430] Homogentisate 1,2-dioxygenase - Vigna angularis [Reaction:R-OOF-1121430] Homogentisate 1,2-dioxygenase - Oryza officinalis [Reaction:R-PAV-1121430] Homogentisate 1,2-dioxygenase - Prunus avium [Reaction:R-MDO-1121430] Homogentisate 1,2-dioxygenase - Malus domestica [Reaction:R-LSA-1121430] Homogentisate 1,2-dioxygenase - Lactuca sativa [Reaction:R-PPA-1121430] Homogentisate 1,2-dioxygenase - Physcomitrella patens [Reaction:R-ORU-1121430] Homogentisate 1,2-dioxygenase - Oryza rufipogon [Reaction:R-NAT-1121430] Homogentisate 1,2-dioxygenase - Nicotiana attenuata [Reaction:R-PDA-1121430] Homogentisate 1,2-dioxygenase - Phoenix dactylifera [Reaction:R-TSP-1121430] Homogentisate 1,2-dioxygenase - Triticum spelta subsp. spelta [Reaction:R-OPU-1121430] Homogentisate 1,2-dioxygenase - Oryza punctata [Reaction:R-STU-1121430] Homogentisate 1,2-dioxygenase - Solanum tuberosum [Reaction:R-GSU-1121430] Homogentisate 1,2-dioxygenase - Galdieria sulphuraria [Reaction:R-TTI-1121430] Homogentisate 1,2-dioxygenase - Triticum timopheevii subsp. timopheevii [Reaction:R-ACH-1121430] Homogentisate 1,2-dioxygenase - Actinidia chinensis [Reaction:R-AHA-1121430] Homogentisate 1,2-dioxygenase - Arabidopsis halleri [Reaction:R-RCH-1121430] Homogentisate 1,2-dioxygenase - Rosa chinensis [Reaction:R-OBR-1121430] Homogentisate 1,2-dioxygenase - Oryza brachyantha [Reaction:R-PTI-1121430] Homogentisate 1,2-dioxygenase - Populus trichocarpa [Reaction:R-CME-1121430] Homogentisate 1,2-dioxygenase - Cyanidioschyzon merolae [Reaction:R-CSI-1121430] Homogentisate 1,2-dioxygenase - Citrus sinensis [Reaction:R-OGR-1121430] Homogentisate 1,2-dioxygenase - Oryza meyeriana var. granulata [Reaction:R-BDI-1121430] Homogentisate 1,2-dioxygenase - Brachypodium distachyon [Reaction:R-BNA-1121430] Homogentisate 1,2-dioxygenase - Brassica napus [Reaction:R-TUR-1121430] Homogentisate 1,2-dioxygenase - Triticum urartu [Reaction:R-TAE-1121430] Homogentisate 1,2-dioxygenase - Triticum aestivum [Reaction:R-CRE-1121430] Homogentisate 1,2-dioxygenase - Chlamydomonas reinhardtii [Reaction:R-AHY-1121430] Homogentisate 1,2-dioxygenase - Arachis hypogaea [Reaction:R-HVU-1121430] Homogentisate 1,2-dioxygenase - Hordeum vulgare [Reaction:R-MGU-1121430] Homogentisate 1,2-dioxygenase - Erythranthe guttata [Reaction:R-ALY-1121430] Homogentisate 1,2-dioxygenase - Arabidopsis lyrata [Reaction:R-OAU-1121430] Homogentisate 1,2-dioxygenase - Oryza australiensis [Reaction:R-CCI-1121430] Homogentisate 1,2-dioxygenase - Corymbia citriodora [Reaction:R-CLA-1121430] Homogentisate 1,2-dioxygenase - Citrullus lanatus [Reaction:R-SHI-1121430] Homogentisate 1,2-dioxygenase - Salvia hispanica [Reaction:R-ZJA-1121430] Homogentisate 1,2-dioxygenase - Zoysia japonica [Reaction:R-PVU-1121430] Homogentisate 1,2-dioxygenase - Phaseolus vulgaris [Reaction:R-ATH-1121430] Homogentisate 1,2-dioxygenase - Arabidopsis thaliana [Reaction:R-SMO-1121430] Homogentisate 1,2-dioxygenase - Selaginella moellendorffii [Reaction:R-OSI-1121430] Homogentisate 1,2-dioxygenase - Oryza sativa Indica Group [Reaction:R-VFA-1121430] Homogentisate 1,2-dioxygenase - Vicia faba var. faba [Reaction:R-OME-1121430] Homogentisate 1,2-dioxygenase - Oryza meridionalis [Reaction:R-VUN-1121430] Homogentisate 1,2-dioxygenase - Vigna unguiculata [Reaction:R-TTU-1121430] Homogentisate 1,2-dioxygenase - Triticum turgidum [Reaction:R-SIN-1121430] Homogentisate 1,2-dioxygenase - Sesamum indicum [Reaction:R-OGL-1121430] Homogentisate 1,2-dioxygenase - Oryza glaberrima [Reaction:R-SLY-1121430] Homogentisate 1,2-dioxygenase - Solanum lycopersicum [Reaction:R-CCA-1121430] Homogentisate 1,2-dioxygenase - Cajanus cajan [Reaction:R-ASA-1121430] Homogentisate 1,2-dioxygenase - Avena sativa [Reaction:R-AOF-1121430] Homogentisate 1,2-dioxygenase - Asparagus officinalis [Reaction:R-MTR-1121430] Homogentisate 1,2-dioxygenase - Medicago truncatula [Reaction:R-MES-1121430] Homogentisate 1,2-dioxygenase - Manihot esculenta [Reaction:R-PHH-1121430] Homogentisate 1,2-dioxygenase - Panicum hallii var. hallii ("HAL2") [Reaction:R-LPE-1121430] Homogentisate 1,2-dioxygenase - Leersia perrieri [Reaction:R-PAB-1121430] Homogentisate 1,2-dioxygenase - Picea abies [Reaction:R-SCR-1121430] Homogentisate 1,2-dioxygenase - Secale cereale [Reaction:R-TPR-1121430] Homogentisate 1,2-dioxygenase - Trifolium pratense [Reaction:R-ADU-1121430] Homogentisate 1,2-dioxygenase - Arachis duranensis [Reaction:R-ITR-1121430] Homogentisate 1,2-dioxygenase - Ipomoea triloba [Reaction:R-HLH-1121430] Homogentisate 1,2-dioxygenase - Humulus lupulus [Reaction:R-GSO-1121430] Homogentisate 1,2-dioxygenase - Glycine soja [Reaction:R-AUM-1121430] Homogentisate 1,2-dioxygenase - Aegilops umbellulata [Reaction:R-OEU-1121430] Homogentisate 1,2-dioxygenase - Olea europaea [Reaction:R-CSC-1121430] Homogentisate 1,2-dioxygenase - Cannabis sativa [Reaction:R-BVU-1121430] Homogentisate 1,2-dioxygenase - Beta vulgaris [Reaction:R-GRA-1121430] Homogentisate 1,2-dioxygenase - Gossypium raimondii [Reaction:R-DCA-1121430] Homogentisate 1,2-dioxygenase - Daucus carota [Reaction:R-JRE-1121430] Homogentisate 1,2-dioxygenase - Juglans regia [Reaction:R-EGR-1121430] Homogentisate 1,2-dioxygenase - Eucalyptus grandis [Reaction:R-SVI-1121430] Homogentisate 1,2-dioxygenase - Setaria viridis [Reaction:R-CCR-1121430] Homogentisate 1,2-dioxygenase - Chondrus crispus [Reaction:R-PSA-1121430] Homogentisate 1,2-dioxygenase - Pisum sativum [Reaction:R-ONI-1121430] Homogentisate 1,2-dioxygenase - Oryza nivara [Reaction:R-LAN-1121430] Homogentisate 1,2-dioxygenase - Lupinus angustifolius [Reaction:R-MPO-1121430] Homogentisate 1,2-dioxygenase - Marchantia polymorpha [Reaction:R-CML-1121430] Homogentisate 1,2-dioxygenase - Cucumis melo [Reaction:R-CRU-1121430] Homogentisate 1,2-dioxygenase - Capsella rubella [Reaction:R-OMI-1121430] Homogentisate 1,2-dioxygenase - Oryza minuta [Reaction:R-ECU-1121430] Homogentisate 1,2-dioxygenase - Eragrostis curvula [Reaction:R-ATR-1121430] Homogentisate 1,2-dioxygenase - Amborella trichopoda [Reaction:R-TCA-1121430] Homogentisate 1,2-dioxygenase - Theobroma cacao [Reaction:R-GMA-1121430] Homogentisate 1,2-dioxygenase - Glycine max [Reaction:R-VRA-1121430] Homogentisate 1,2-dioxygenase - Vigna radiata [Reaction:R-CAN-1121430] Homogentisate 1,2-dioxygenase - Capsicum annuum [Reaction:R-JCU-1121430] Homogentisate 1,2-dioxygenase - Jatropha curcas [Reaction:R-FCR-1121430] Homogentisate 1,2-dioxygenase - Ficus carica [Reaction:R-PPE-1121430] Homogentisate 1,2-dioxygenase - Prunus persica [Reaction:R-ACO-1121430] Homogentisate 1,2-dioxygenase - Ananas comosus [Reaction:R-BJU-1121430] Homogentisate 1,2-dioxygenase - Brassica juncea [Reaction:R-NCO-1121430] Homogentisate 1,2-dioxygenase - Nymphaea colorata [Reaction:R-CCN-1121430] Homogentisate 1,2-dioxygenase - Coffea canephora [Reaction:R-PSO-1121430] Homogentisate 1,2-dioxygenase - Papaver somniferum [Reaction:R-LST-1121430] Homogentisate 1,2-dioxygenase - Lathyrus sativus [Reaction:R-NNU-1121430] Homogentisate 1,2-dioxygenase - Nelumbo nucifera [Reaction:R-MAC-1121430] Homogentisate 1,2-dioxygenase - Musa acuminata [Reaction:R-BRA-1121430] Homogentisate 1,2-dioxygenase - Brassica rapa [Reaction:R-LPR-1121430] Homogentisate 1,2-dioxygenase - Lolium perenne [Reaction:R-OLO-1121430] Homogentisate 1,2-dioxygenase - Oryza longistaminata [Reaction:R-PHA-1121430] Homogentisate 1,2-dioxygenase - Panicum hallii ("FIL2") [Reaction:R-CCD-1121430] Homogentisate 1,2-dioxygenase - Cynara cardunculus var. scolymus [Reaction:R-OBA-1121430] Homogentisate 1,2-dioxygenase - Oryza barthii [Reaction:R-CSK-1121430] Homogentisate 1,2-dioxygenase - Cannabis sativa subsp. indica [Reaction:R-ZMY-1121430] Homogentisate 1,2-dioxygenase - Zea mays ver5 [Reaction:R-AIP-1121430] Homogentisate 1,2-dioxygenase - Arachis ipaensis [Reaction:R-TDI-1121430] Homogentisate 1,2-dioxygenase - Triticum dicoccoides [Reaction:R-FEX-1121430] Homogentisate 1,2-dioxygenase - Fraxinus excelsior (European ash) [Reaction:R-FVE-1121430] Homogentisate 1,2-dioxygenase - Fragaria vesca [Reaction:R-DRO-1121430] Homogentisate 1,2-dioxygenase - Dioscorea rotundata [Reaction:R-SBI-1121430] Homogentisate 1,2-dioxygenase - Sorghum bicolor [Reaction:R-CQI-1121430] Homogentisate 1,2-dioxygenase - Chenopodium quinoa [Reaction:R-CCP-1121430] Homogentisate 1,2-dioxygenase - Corchorus capsularis [Reaction:R-QSU-1121430] Homogentisate 1,2-dioxygenase - Quercus suber
output	[SimpleEntity:R-ALL-31135] 4MAA [cytosol]
precedingEvent	[Reaction:R-OSA-1120341] Conversion of HPP to HGTA - Oryza sativa
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1121430

Referrals

(hasEvent)	[Pathway:R-OSA-1119506] tyrosine degradation I - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-1120380] Maleylacetoacetate isomerase - Oryza sativa

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