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Shikimate 5-dehydrogenase

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catalystActivity	[CatalystActivity:1118739] shikimate 3-dehydrogenase (NADP+) activity of Shikimate / 3-dehydroquinate dehydrogenase [plastid stroma]
compartment	[Compartment:1141] plastid stroma
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:26531] EC:1.1.1.25 [DatabaseIdentifier:1138236] RiceCyc:SHIKIMATE-5-DEHYDROGENASE-RXN
dbId	1121357
displayName	Shikimate 5-dehydrogenase
eventOf	[Pathway:R-OSA-1119430] Chorismate biosynthesis - Oryza sativa
followingEvent	[Reaction:R-OSA-1120248] shikimate-kinase - Oryza sativa
input	[SimpleEntity:R-ALL-1131465] 3-dehydro-shikimate [plastid stroma] [SimpleEntity:R-ALL-1168706] NADPH [plastid stroma]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11529250] Elser, Justin, 2025-03-27
name	Shikimate 5-dehydrogenase 5-dehydroshikimate reductase biochemicalReaction90748
orthologousEvent	[Reaction:R-NCO-1121357] Shikimate 5-dehydrogenase - Nymphaea colorata [Reaction:R-CST-1121357] Shikimate 5-dehydrogenase - Camelina sativa [Reaction:R-CSC-1121357] Shikimate 5-dehydrogenase - Cannabis sativa [Reaction:R-LPE-1121357] Shikimate 5-dehydrogenase - Leersia perrieri [Reaction:R-MGU-1121357] Shikimate 5-dehydrogenase - Erythranthe guttata [Reaction:R-CAR-1121357] Shikimate 5-dehydrogenase - Cicer arietinum [Reaction:R-OLO-1121357] Shikimate 5-dehydrogenase - Oryza longistaminata [Reaction:R-CCP-1121357] Shikimate 5-dehydrogenase - Corchorus capsularis [Reaction:R-MES-1121357] Shikimate 5-dehydrogenase - Manihot esculenta [Reaction:R-RCH-1121357] Shikimate 5-dehydrogenase - Rosa chinensis [Reaction:R-LSA-1121357] Shikimate 5-dehydrogenase - Lactuca sativa [Reaction:R-ATA-1121357] Shikimate 5-dehydrogenase - Aegilops tauschii [Reaction:R-AHA-1121357] Shikimate 5-dehydrogenase - Arabidopsis halleri [Reaction:R-MPO-1121357] Shikimate 5-dehydrogenase - Marchantia polymorpha [Reaction:R-OME-1121357] Shikimate 5-dehydrogenase - Oryza meridionalis [Reaction:R-OPU-1121357] Shikimate 5-dehydrogenase - Oryza punctata [Reaction:R-PAV-1121357] Shikimate 5-dehydrogenase - Prunus avium [Reaction:R-OMI-1121357] Shikimate 5-dehydrogenase - Oryza minuta [Reaction:R-AHY-1121357] Shikimate 5-dehydrogenase - Arachis hypogaea [Reaction:R-BJU-1121357] Shikimate 5-dehydrogenase - Brassica juncea [Reaction:R-CAN-1121357] Shikimate 5-dehydrogenase - Capsicum annuum [Reaction:R-CRE-1121357] Shikimate 5-dehydrogenase - Chlamydomonas reinhardtii [Reaction:R-PED-1121357] Shikimate 5-dehydrogenase - Phyllostachys edulis [Reaction:R-OBR-1121357] Shikimate 5-dehydrogenase - Oryza brachyantha [Reaction:R-PDA-1121357] Shikimate 5-dehydrogenase - Phoenix dactylifera [Reaction:R-FCR-1121357] Shikimate 5-dehydrogenase - Ficus carica [Reaction:R-CLA-1121357] Shikimate 5-dehydrogenase - Citrullus lanatus [Reaction:R-SBI-1121357] Shikimate 5-dehydrogenase - Sorghum bicolor [Reaction:R-CSA-1121357] Shikimate 5-dehydrogenase - Cucumis sativus [Reaction:R-BVU-1121357] Shikimate 5-dehydrogenase - Beta vulgaris [Reaction:R-ACH-1121357] Shikimate 5-dehydrogenase - Actinidia chinensis [Reaction:R-PTA-1121357] Shikimate 5-dehydrogenase - Pinus taeda [Reaction:R-TSP-1121357] Shikimate 5-dehydrogenase - Triticum spelta subsp. spelta [Reaction:R-CQI-1121357] Shikimate 5-dehydrogenase - Chenopodium quinoa [Reaction:R-ACO-1121357] Shikimate 5-dehydrogenase - Ananas comosus [Reaction:R-JCU-1121357] Shikimate 5-dehydrogenase - Jatropha curcas [Reaction:R-FEX-1121357] Shikimate 5-dehydrogenase - Fraxinus excelsior (European ash) [Reaction:R-TTU-1121357] Shikimate 5-dehydrogenase - Triticum turgidum [Reaction:R-CCI-1121357] Shikimate 5-dehydrogenase - Corymbia citriodora [Reaction:R-GRA-1121357] Shikimate 5-dehydrogenase - Gossypium raimondii [Reaction:R-DEX-1121357] Shikimate 5-dehydrogenase - Digitaria exilis [Reaction:R-SIN-1121357] Shikimate 5-dehydrogenase - Sesamum indicum [Reaction:R-GMA-1121357] Shikimate 5-dehydrogenase - Glycine max [Reaction:R-PSO-1121357] Shikimate 5-dehydrogenase - Papaver somniferum [Reaction:R-TAE-1121357] Shikimate 5-dehydrogenase - Triticum aestivum [Reaction:R-ZJA-1121357] Shikimate 5-dehydrogenase - Zoysia japonica [Reaction:R-BOL-1121357] Shikimate 5-dehydrogenase - Brassica oleracea [Reaction:R-AUM-1121357] Shikimate 5-dehydrogenase - Aegilops umbellulata [Reaction:R-OEU-1121357] Shikimate 5-dehydrogenase - Olea europaea [Reaction:R-TTI-1121357] Shikimate 5-dehydrogenase - Triticum timopheevii subsp. timopheevii [Reaction:R-HAN-1121357] Shikimate 5-dehydrogenase - Helianthus annuus [Reaction:R-TPR-1121357] Shikimate 5-dehydrogenase - Trifolium pratense [Reaction:R-JRE-1121357] Shikimate 5-dehydrogenase - Juglans regia [Reaction:R-SIT-1121357] Shikimate 5-dehydrogenase - Setaria italica [Reaction:R-OSI-1121357] Shikimate 5-dehydrogenase - Oryza sativa Indica Group [Reaction:R-OGL-1121357] Shikimate 5-dehydrogenase - Oryza glaberrima [Reaction:R-PPE-1121357] Shikimate 5-dehydrogenase - Prunus persica [Reaction:R-SCR-1121357] Shikimate 5-dehydrogenase - Secale cereale [Reaction:R-GSU-1121357] Shikimate 5-dehydrogenase - Galdieria sulphuraria [Reaction:R-ZMY-1121357] Shikimate 5-dehydrogenase - Zea mays ver5 [Reaction:R-ECU-1121357] Shikimate 5-dehydrogenase - Eragrostis curvula [Reaction:R-AIP-1121357] Shikimate 5-dehydrogenase - Arachis ipaensis [Reaction:R-LST-1121357] Shikimate 5-dehydrogenase - Lathyrus sativus [Reaction:R-SLY-1121357] Shikimate 5-dehydrogenase - Solanum lycopersicum [Reaction:R-AOF-1121357] Shikimate 5-dehydrogenase - Asparagus officinalis [Reaction:R-ASA-1121357] Shikimate 5-dehydrogenase - Avena sativa [Reaction:R-DCA-1121357] Shikimate 5-dehydrogenase - Daucus carota [Reaction:R-OGR-1121357] Shikimate 5-dehydrogenase - Oryza meyeriana var. granulata [Reaction:R-FVE-1121357] Shikimate 5-dehydrogenase - Fragaria vesca [Reaction:R-ALY-1121357] Shikimate 5-dehydrogenase - Arabidopsis lyrata [Reaction:R-CML-1121357] Shikimate 5-dehydrogenase - Cucumis melo [Reaction:R-ATH-1121357] Shikimate 5-dehydrogenase - Arabidopsis thaliana [Reaction:R-CCR-1121357] Shikimate 5-dehydrogenase - Chondrus crispus [Reaction:R-COL-1121357] Shikimate 5-dehydrogenase - Corchorus olitorius [Reaction:R-SVI-1121357] Shikimate 5-dehydrogenase - Setaria viridis [Reaction:R-OLU-1121357] Shikimate 5-dehydrogenase - Ostreococcus lucimarinus [Reaction:R-ITR-1121357] Shikimate 5-dehydrogenase - Ipomoea triloba [Reaction:R-SSP-1121357] Shikimate 5-dehydrogenase - Saccharum spontaneum [Reaction:R-BNA-1121357] Shikimate 5-dehydrogenase - Brassica napus [Reaction:R-CRU-1121357] Shikimate 5-dehydrogenase - Capsella rubella [Reaction:R-MTR-1121357] Shikimate 5-dehydrogenase - Medicago truncatula [Reaction:R-HVU-1121357] Shikimate 5-dehydrogenase - Hordeum vulgare [Reaction:R-PHH-1121357] Shikimate 5-dehydrogenase - Panicum hallii var. hallii ("HAL2") [Reaction:R-EGR-1121357] Shikimate 5-dehydrogenase - Eucalyptus grandis [Reaction:R-NNU-1121357] Shikimate 5-dehydrogenase - Nelumbo nucifera [Reaction:R-VAN-1121357] Shikimate 5-dehydrogenase - Vigna angularis [Reaction:R-LPR-1121357] Shikimate 5-dehydrogenase - Lolium perenne [Reaction:R-CCN-1121357] Shikimate 5-dehydrogenase - Coffea canephora [Reaction:R-HLH-1121357] Shikimate 5-dehydrogenase - Humulus lupulus [Reaction:R-ETE-1121357] Shikimate 5-dehydrogenase - Eragrostis tef [Reaction:R-CSI-1121357] Shikimate 5-dehydrogenase - Citrus sinensis [Reaction:R-PPA-1121357] Shikimate 5-dehydrogenase - Physcomitrella patens [Reaction:R-CCA-1121357] Shikimate 5-dehydrogenase - Cajanus cajan [Reaction:R-OES-1121357] Shikimate 5-dehydrogenase - Olea europaea var. sylvestris [Reaction:R-LAN-1121357] Shikimate 5-dehydrogenase - Lupinus angustifolius [Reaction:R-CME-1121357] Shikimate 5-dehydrogenase - Cyanidioschyzon merolae [Reaction:R-CBA-1121357] Shikimate 5-dehydrogenase - Chara braunii [Reaction:R-SPC-1121357] Shikimate 5-dehydrogenase - Synechocystis sp. PCC 6803 [Reaction:R-CCL-1121357] Shikimate 5-dehydrogenase - Citrus clementina [Reaction:R-BRA-1121357] Shikimate 5-dehydrogenase - Brassica rapa [Reaction:R-BDI-1121357] Shikimate 5-dehydrogenase - Brachypodium distachyon [Reaction:R-OAU-1121357] Shikimate 5-dehydrogenase - Oryza australiensis [Reaction:R-OBA-1121357] Shikimate 5-dehydrogenase - Oryza barthii [Reaction:R-PHA-1121357] Shikimate 5-dehydrogenase - Panicum hallii ("FIL2") [Reaction:R-VRA-1121357] Shikimate 5-dehydrogenase - Vigna radiata [Reaction:R-TUR-1121357] Shikimate 5-dehydrogenase - Triticum urartu [Reaction:R-QLO-1121357] Shikimate 5-dehydrogenase - Quercus lobata [Reaction:R-ECG-1121357] Shikimate 5-dehydrogenase - Echinochloa crus-galli [Reaction:R-CCD-1121357] Shikimate 5-dehydrogenase - Cynara cardunculus var. scolymus [Reaction:R-HLP-1121357] Shikimate 5-dehydrogenase - Humulus lupulus var. lupulus [Reaction:R-OOF-1121357] Shikimate 5-dehydrogenase - Oryza officinalis [Reaction:R-NAT-1121357] Shikimate 5-dehydrogenase - Nicotiana attenuata [Reaction:R-PSA-1121357] Shikimate 5-dehydrogenase - Pisum sativum [Reaction:R-ADU-1121357] Shikimate 5-dehydrogenase - Arachis duranensis [Reaction:R-VFA-1121357] Shikimate 5-dehydrogenase - Vicia faba var. faba [Reaction:R-QSU-1121357] Shikimate 5-dehydrogenase - Quercus suber [Reaction:R-MDO-1121357] Shikimate 5-dehydrogenase - Malus domestica [Reaction:R-TDI-1121357] Shikimate 5-dehydrogenase - Triticum dicoccoides [Reaction:R-TCA-1121357] Shikimate 5-dehydrogenase - Theobroma cacao [Reaction:R-CSK-1121357] Shikimate 5-dehydrogenase - Cannabis sativa subsp. indica [Reaction:R-SMO-1121357] Shikimate 5-dehydrogenase - Selaginella moellendorffii [Reaction:R-VVN-1121357] Shikimate 5-dehydrogenase - Vitis vinifera [Reaction:R-PTI-1121357] Shikimate 5-dehydrogenase - Populus trichocarpa [Reaction:R-PVU-1121357] Shikimate 5-dehydrogenase - Phaseolus vulgaris [Reaction:R-ATR-1121357] Shikimate 5-dehydrogenase - Amborella trichopoda [Reaction:R-GSO-1121357] Shikimate 5-dehydrogenase - Glycine soja [Reaction:R-PVE-1121357] Shikimate 5-dehydrogenase - Pistacia vera [Reaction:R-ZMA-1121357] Shikimate 5-dehydrogenase - Zea mays [Reaction:R-PAB-1121357] Shikimate 5-dehydrogenase - Picea abies [Reaction:R-VUN-1121357] Shikimate 5-dehydrogenase - Vigna unguiculata
output	[SimpleEntity:R-ALL-1168698] NADP+ [plastid stroma] [SimpleEntity:R-ALL-4721205] SKM [plastid stroma]
precedingEvent	[Reaction:R-OSA-1120129] 3-dehydroquinate dehydratase - Oryza sativa
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1121357
summation	[Summation:4721225] 3-dehydro-shikimate is converted into shikimate by enzymatic...

Referrals

(hasEvent)	[Pathway:R-OSA-1119430] Chorismate biosynthesis - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-1120248] shikimate-kinase - Oryza sativa