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pyrroline-5-carboxylate reductase

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catalystActivity	[CatalystActivity:1118691] pyrroline-5-carboxylate reductase activity of pyrroline-5-carboxylate reductase (LOC_OS01G71990.1) [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:26859] EC:1.5.1.2 [DatabaseIdentifier:1139289] RiceCyc:PYRROLINECARBREDUCT-RXN
dbId	1121255
displayName	pyrroline-5-carboxylate reductase
eventOf	[Pathway:R-OSA-1119631] Proline biosynthesis I - Oryza sativa [Pathway:R-OSA-1119318] Proline biosynthesis V (from arginine) - Oryza sativa
input	[SimpleEntity:R-ALL-35305] 1PYR-5COOH [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [DefinedSet:R-ALL-428206] NAD(P)H [cytosol]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	pyrroline-5-carboxylate reductase P5CR biochemicalReaction79580
orthologousEvent	[Reaction:R-ADU-1121255] pyrroline-5-carboxylate reductase - Arachis duranensis [Reaction:R-ITR-1121255] pyrroline-5-carboxylate reductase - Ipomoea triloba [Reaction:R-PHA-1121255] pyrroline-5-carboxylate reductase - Panicum hallii ("FIL2") [Reaction:R-CRU-1121255] pyrroline-5-carboxylate reductase - Capsella rubella [Reaction:R-NNU-1121255] pyrroline-5-carboxylate reductase - Nelumbo nucifera [Reaction:R-LPE-1121255] pyrroline-5-carboxylate reductase - Leersia perrieri [Reaction:R-FVE-1121255] pyrroline-5-carboxylate reductase - Fragaria vesca [Reaction:R-QLO-1121255] pyrroline-5-carboxylate reductase - Quercus lobata [Reaction:R-OEU-1121255] pyrroline-5-carboxylate reductase - Olea europaea [Reaction:R-OOF-1121255] pyrroline-5-carboxylate reductase - Oryza officinalis [Reaction:R-PTI-1121255] pyrroline-5-carboxylate reductase - Populus trichocarpa [Reaction:R-CSK-1121255] pyrroline-5-carboxylate reductase - Cannabis sativa subsp. indica [Reaction:R-SBI-1121255] pyrroline-5-carboxylate reductase - Sorghum bicolor [Reaction:R-PSA-1121255] pyrroline-5-carboxylate reductase - Pisum sativum [Reaction:R-TTU-1121255] pyrroline-5-carboxylate reductase - Triticum turgidum [Reaction:R-ATR-1121255] pyrroline-5-carboxylate reductase - Amborella trichopoda [Reaction:R-OAU-1121255] pyrroline-5-carboxylate reductase - Oryza australiensis [Reaction:R-SIT-1121255] pyrroline-5-carboxylate reductase - Setaria italica [Reaction:R-MGU-1121255] pyrroline-5-carboxylate reductase - Erythranthe guttata [Reaction:R-DCA-1121255] pyrroline-5-carboxylate reductase - Daucus carota [Reaction:R-PPE-1121255] pyrroline-5-carboxylate reductase - Prunus persica [Reaction:R-CCR-1121255] pyrroline-5-carboxylate reductase - Chondrus crispus [Reaction:R-AUM-1121255] pyrroline-5-carboxylate reductase - Aegilops umbellulata [Reaction:R-GSU-1121255] pyrroline-5-carboxylate reductase - Galdieria sulphuraria [Reaction:R-TDI-1121255] pyrroline-5-carboxylate reductase - Triticum dicoccoides [Reaction:R-OGL-1121255] pyrroline-5-carboxylate reductase - Oryza glaberrima [Reaction:R-ECU-1121255] pyrroline-5-carboxylate reductase - Eragrostis curvula [Reaction:R-PVU-1121255] pyrroline-5-carboxylate reductase - Phaseolus vulgaris [Reaction:R-DEX-1121255] pyrroline-5-carboxylate reductase - Digitaria exilis [Reaction:R-MPO-1121255] pyrroline-5-carboxylate reductase - Marchantia polymorpha [Reaction:R-HVU-1121255] pyrroline-5-carboxylate reductase - Hordeum vulgare [Reaction:R-VAN-1121255] pyrroline-5-carboxylate reductase - Vigna angularis [Reaction:R-ATA-1121255] pyrroline-5-carboxylate reductase - Aegilops tauschii [Reaction:R-SPC-1121255] pyrroline-5-carboxylate reductase - Synechocystis sp. PCC 6803 [Reaction:R-CCN-1121255] pyrroline-5-carboxylate reductase - Coffea canephora [Reaction:R-CAR-1121255] pyrroline-5-carboxylate reductase - Cicer arietinum [Reaction:R-NAT-1121255] pyrroline-5-carboxylate reductase - Nicotiana attenuata [Reaction:R-SSP-1121255] pyrroline-5-carboxylate reductase - Saccharum spontaneum [Reaction:R-PPA-1121255] pyrroline-5-carboxylate reductase - Physcomitrella patens [Reaction:R-TSP-1121255] pyrroline-5-carboxylate reductase - Triticum spelta subsp. spelta [Reaction:R-CCP-1121255] pyrroline-5-carboxylate reductase - Corchorus capsularis [Reaction:R-BJU-1121255] pyrroline-5-carboxylate reductase - Brassica juncea [Reaction:R-ZJA-1121255] pyrroline-5-carboxylate reductase - Zoysia japonica [Reaction:R-TCA-1121255] pyrroline-5-carboxylate reductase - Theobroma cacao [Reaction:R-CCI-1121255] pyrroline-5-carboxylate reductase - Corymbia citriodora [Reaction:R-JRE-1121255] pyrroline-5-carboxylate reductase - Juglans regia [Reaction:R-SVI-1121255] pyrroline-5-carboxylate reductase - Setaria viridis [Reaction:R-PVE-1121255] pyrroline-5-carboxylate reductase - Pistacia vera [Reaction:R-STU-1121255] pyrroline-5-carboxylate reductase - Solanum tuberosum [Reaction:R-ACO-1121255] pyrroline-5-carboxylate reductase - Ananas comosus [Reaction:R-GSO-1121255] pyrroline-5-carboxylate reductase - Glycine soja [Reaction:R-VFA-1121255] pyrroline-5-carboxylate reductase - Vicia faba var. faba [Reaction:R-AIP-1121255] pyrroline-5-carboxylate reductase - Arachis ipaensis [Reaction:R-CME-1121255] pyrroline-5-carboxylate reductase - Cyanidioschyzon merolae [Reaction:R-TTI-1121255] pyrroline-5-carboxylate reductase - Triticum timopheevii subsp. timopheevii [Reaction:R-PED-1121255] pyrroline-5-carboxylate reductase - Phyllostachys edulis [Reaction:R-PHH-1121255] pyrroline-5-carboxylate reductase - Panicum hallii var. hallii ("HAL2") [Reaction:R-LSA-1121255] pyrroline-5-carboxylate reductase - Lactuca sativa [Reaction:R-QSU-1121255] pyrroline-5-carboxylate reductase - Quercus suber [Reaction:R-PSO-1121255] pyrroline-5-carboxylate reductase - Papaver somniferum [Reaction:R-CSI-1121255] pyrroline-5-carboxylate reductase - Citrus sinensis [Reaction:R-VRA-1121255] pyrroline-5-carboxylate reductase - Vigna radiata [Reaction:R-SLY-1121255] pyrroline-5-carboxylate reductase - Solanum lycopersicum [Reaction:R-GMA-1121255] pyrroline-5-carboxylate reductase - Glycine max [Reaction:R-MES-1121255] pyrroline-5-carboxylate reductase - Manihot esculenta [Reaction:R-TUR-1121255] pyrroline-5-carboxylate reductase - Triticum urartu [Reaction:R-TPR-1121255] pyrroline-5-carboxylate reductase - Trifolium pratense [Reaction:R-ETE-1121255] pyrroline-5-carboxylate reductase - Eragrostis tef [Reaction:R-CQI-1121255] pyrroline-5-carboxylate reductase - Chenopodium quinoa [Reaction:R-SIN-1121255] pyrroline-5-carboxylate reductase - Sesamum indicum [Reaction:R-OMI-1121255] pyrroline-5-carboxylate reductase - Oryza minuta [Reaction:R-MDO-1121255] pyrroline-5-carboxylate reductase - Malus domestica [Reaction:R-DRO-1121255] pyrroline-5-carboxylate reductase - Dioscorea rotundata [Reaction:R-NCO-1121255] pyrroline-5-carboxylate reductase - Nymphaea colorata [Reaction:R-CSC-1121255] pyrroline-5-carboxylate reductase - Cannabis sativa [Reaction:R-RCH-1121255] pyrroline-5-carboxylate reductase - Rosa chinensis [Reaction:R-OBR-1121255] pyrroline-5-carboxylate reductase - Oryza brachyantha [Reaction:R-CRE-1121255] pyrroline-5-carboxylate reductase - Chlamydomonas reinhardtii [Reaction:R-VVN-1121255] pyrroline-5-carboxylate reductase - Vitis vinifera [Reaction:R-BNA-1121255] pyrroline-5-carboxylate reductase - Brassica napus [Reaction:R-PDA-1121255] pyrroline-5-carboxylate reductase - Phoenix dactylifera [Reaction:R-GRA-1121255] pyrroline-5-carboxylate reductase - Gossypium raimondii [Reaction:R-LAN-1121255] pyrroline-5-carboxylate reductase - Lupinus angustifolius [Reaction:R-OES-1121255] pyrroline-5-carboxylate reductase - Olea europaea var. sylvestris [Reaction:R-OSI-1121255] pyrroline-5-carboxylate reductase - Oryza sativa Indica Group [Reaction:R-CCD-1121255] pyrroline-5-carboxylate reductase - Cynara cardunculus var. scolymus [Reaction:R-OGR-1121255] pyrroline-5-carboxylate reductase - Oryza meyeriana var. granulata [Reaction:R-VUN-1121255] pyrroline-5-carboxylate reductase - Vigna unguiculata [Reaction:R-BRA-1121255] pyrroline-5-carboxylate reductase - Brassica rapa [Reaction:R-BVU-1121255] pyrroline-5-carboxylate reductase - Beta vulgaris [Reaction:R-ASA-1121255] pyrroline-5-carboxylate reductase - Avena sativa [Reaction:R-COL-1121255] pyrroline-5-carboxylate reductase - Corchorus olitorius [Reaction:R-CLA-1121255] pyrroline-5-carboxylate reductase - Citrullus lanatus [Reaction:R-BOL-1121255] pyrroline-5-carboxylate reductase - Brassica oleracea [Reaction:R-CML-1121255] pyrroline-5-carboxylate reductase - Cucumis melo [Reaction:R-ACH-1121255] pyrroline-5-carboxylate reductase - Actinidia chinensis [Reaction:R-HAN-1121255] pyrroline-5-carboxylate reductase - Helianthus annuus [Reaction:R-CSA-1121255] pyrroline-5-carboxylate reductase - Cucumis sativus [Reaction:R-MTR-1121255] pyrroline-5-carboxylate reductase - Medicago truncatula [Reaction:R-HLP-1121255] pyrroline-5-carboxylate reductase - Humulus lupulus var. lupulus [Reaction:R-BDI-1121255] pyrroline-5-carboxylate reductase - Brachypodium distachyon [Reaction:R-FCR-1121255] pyrroline-5-carboxylate reductase - Ficus carica [Reaction:R-AHA-1121255] pyrroline-5-carboxylate reductase - Arabidopsis halleri [Reaction:R-ZMY-1121255] pyrroline-5-carboxylate reductase - Zea mays ver5 [Reaction:R-LST-1121255] pyrroline-5-carboxylate reductase - Lathyrus sativus [Reaction:R-ZMA-1121255] pyrroline-5-carboxylate reductase - Zea mays [Reaction:R-SHI-1121255] pyrroline-5-carboxylate reductase - Salvia hispanica [Reaction:R-OLO-1121255] pyrroline-5-carboxylate reductase - Oryza longistaminata [Reaction:R-CST-1121255] pyrroline-5-carboxylate reductase - Camelina sativa [Reaction:R-CCL-1121255] pyrroline-5-carboxylate reductase - Citrus clementina [Reaction:R-ALY-1121255] pyrroline-5-carboxylate reductase - Arabidopsis lyrata [Reaction:R-ECG-1121255] pyrroline-5-carboxylate reductase - Echinochloa crus-galli [Reaction:R-CCA-1121255] pyrroline-5-carboxylate reductase - Cajanus cajan [Reaction:R-AHY-1121255] pyrroline-5-carboxylate reductase - Arachis hypogaea [Reaction:R-LPR-1121255] pyrroline-5-carboxylate reductase - Lolium perenne [Reaction:R-MAC-1121255] pyrroline-5-carboxylate reductase - Musa acuminata [Reaction:R-ORU-1121255] pyrroline-5-carboxylate reductase - Oryza rufipogon [Reaction:R-AOF-1121255] pyrroline-5-carboxylate reductase - Asparagus officinalis [Reaction:R-OPU-1121255] pyrroline-5-carboxylate reductase - Oryza punctata [Reaction:R-SCR-1121255] pyrroline-5-carboxylate reductase - Secale cereale [Reaction:R-ATH-1121255] pyrroline-5-carboxylate reductase - Arabidopsis thaliana [Reaction:R-SMO-1121255] pyrroline-5-carboxylate reductase - Selaginella moellendorffii [Reaction:R-FEX-1121255] pyrroline-5-carboxylate reductase - Fraxinus excelsior (European ash) [Reaction:R-OLU-1121255] pyrroline-5-carboxylate reductase - Ostreococcus lucimarinus [Reaction:R-TAE-1121255] pyrroline-5-carboxylate reductase - Triticum aestivum [Reaction:R-EGR-1121255] pyrroline-5-carboxylate reductase - Eucalyptus grandis [Reaction:R-ONI-1121255] pyrroline-5-carboxylate reductase - Oryza nivara
output	[SimpleEntity:R-ALL-113538] L-Pro [cytosol] [DefinedSet:R-ALL-428218] NAD(P)+ [cytosol]
precedingEvent	[Reaction:R-OSA-1120680] L-glutamate gamma-semialdehyde->H2O+pyrroline 5-carboxylate - Oryza sativa
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1121255
summation	[Summation:2677908] Pyrroline 5-carboxylate is converted to L-proline by enzymat...

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