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D-alanine--D-alanine ligase

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catalystActivity	[CatalystActivity:1118520] D-alanine-D-alanine ligase activity of D-alanine--D-alanine ligase [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:28144] EC:6.3.2.4 [DatabaseIdentifier:1137172] RiceCyc:DALADALALIG-RXN
dbId	1121138
displayName	D-alanine--D-alanine ligase
edited	[InstanceEdit:3239856] Beorchia, Dylan, 2013-01-31
eventOf	[Pathway:R-OSA-1119436] Peptidoglycan biosynthesis I - Oryza sativa
followingEvent	[Reaction:R-OSA-1120868] UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl- D-alanine ligase - Oryza sativa
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] 2 × [SimpleEntity:R-ALL-376188] D-Ala [cytosol]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	D-alanine--D-alanine ligase D-Ala-D-Ala synthetase D-alanyl-D-alanine synthetase D-alanylalanine synthetase biochemicalReaction6928
orthologousEvent	[Reaction:R-OAU-1121138] D-alanine--D-alanine ligase - Oryza australiensis [Reaction:R-LPE-1121138] D-alanine--D-alanine ligase - Leersia perrieri [Reaction:R-ASA-1121138] D-alanine--D-alanine ligase - Avena sativa [Reaction:R-OES-1121138] D-alanine--D-alanine ligase - Olea europaea var. sylvestris [Reaction:R-TUR-1121138] D-alanine--D-alanine ligase - Triticum urartu [Reaction:R-CAN-1121138] D-alanine--D-alanine ligase - Capsicum annuum [Reaction:R-PAV-1121138] D-alanine--D-alanine ligase - Prunus avium [Reaction:R-GSO-1121138] D-alanine--D-alanine ligase - Glycine soja [Reaction:R-TTU-1121138] D-alanine--D-alanine ligase - Triticum turgidum [Reaction:R-VFA-1121138] D-alanine--D-alanine ligase - Vicia faba var. faba [Reaction:R-JRE-1121138] D-alanine--D-alanine ligase - Juglans regia [Reaction:R-OME-1121138] D-alanine--D-alanine ligase - Oryza meridionalis [Reaction:R-CCN-1121138] D-alanine--D-alanine ligase - Coffea canephora [Reaction:R-AHA-1121138] D-alanine--D-alanine ligase - Arabidopsis halleri [Reaction:R-TAE-1121138] D-alanine--D-alanine ligase - Triticum aestivum [Reaction:R-ACH-1121138] D-alanine--D-alanine ligase - Actinidia chinensis [Reaction:R-SHI-1121138] D-alanine--D-alanine ligase - Salvia hispanica [Reaction:R-ZMY-1121138] D-alanine--D-alanine ligase - Zea mays ver5 [Reaction:R-ALY-1121138] D-alanine--D-alanine ligase - Arabidopsis lyrata [Reaction:R-FEX-1121138] D-alanine--D-alanine ligase - Fraxinus excelsior (European ash) [Reaction:R-RCH-1121138] D-alanine--D-alanine ligase - Rosa chinensis [Reaction:R-OLO-1121138] D-alanine--D-alanine ligase - Oryza longistaminata [Reaction:R-OBR-1121138] D-alanine--D-alanine ligase - Oryza brachyantha [Reaction:R-OOF-1121138] D-alanine--D-alanine ligase - Oryza officinalis [Reaction:R-ECU-1121138] D-alanine--D-alanine ligase - Eragrostis curvula [Reaction:R-CAR-1121138] D-alanine--D-alanine ligase - Cicer arietinum [Reaction:R-OGU-1121138] D-alanine--D-alanine ligase - Oryza glumaepatula [Reaction:R-CCA-1121138] D-alanine--D-alanine ligase - Cajanus cajan [Reaction:R-OPU-1121138] D-alanine--D-alanine ligase - Oryza punctata [Reaction:R-CSA-1121138] D-alanine--D-alanine ligase - Cucumis sativus [Reaction:R-TCA-1121138] D-alanine--D-alanine ligase - Theobroma cacao [Reaction:R-SMO-1121138] D-alanine--D-alanine ligase - Selaginella moellendorffii [Reaction:R-PDA-1121138] D-alanine--D-alanine ligase - Phoenix dactylifera [Reaction:R-OEU-1121138] D-alanine--D-alanine ligase - Olea europaea [Reaction:R-ZMA-1121138] D-alanine--D-alanine ligase - Zea mays [Reaction:R-CCP-1121138] D-alanine--D-alanine ligase - Corchorus capsularis [Reaction:R-BOL-1121138] D-alanine--D-alanine ligase - Brassica oleracea [Reaction:R-PSA-1121138] D-alanine--D-alanine ligase - Pisum sativum [Reaction:R-MPO-1121138] D-alanine--D-alanine ligase - Marchantia polymorpha [Reaction:R-TSP-1121138] D-alanine--D-alanine ligase - Triticum spelta subsp. spelta [Reaction:R-QLO-1121138] D-alanine--D-alanine ligase - Quercus lobata [Reaction:R-BRA-1121138] D-alanine--D-alanine ligase - Brassica rapa [Reaction:R-CSC-1121138] D-alanine--D-alanine ligase - Cannabis sativa [Reaction:R-HAN-1121138] D-alanine--D-alanine ligase - Helianthus annuus [Reaction:R-CSK-1121138] D-alanine--D-alanine ligase - Cannabis sativa subsp. indica [Reaction:R-VAN-1121138] D-alanine--D-alanine ligase - Vigna angularis [Reaction:R-CSI-1121138] D-alanine--D-alanine ligase - Citrus sinensis [Reaction:R-PPE-1121138] D-alanine--D-alanine ligase - Prunus persica [Reaction:R-ETE-1121138] D-alanine--D-alanine ligase - Eragrostis tef [Reaction:R-MES-1121138] D-alanine--D-alanine ligase - Manihot esculenta [Reaction:R-ADU-1121138] D-alanine--D-alanine ligase - Arachis duranensis [Reaction:R-TPR-1121138] D-alanine--D-alanine ligase - Trifolium pratense [Reaction:R-SBI-1121138] D-alanine--D-alanine ligase - Sorghum bicolor [Reaction:R-PSO-1121138] D-alanine--D-alanine ligase - Papaver somniferum [Reaction:R-HVU-1121138] D-alanine--D-alanine ligase - Hordeum vulgare [Reaction:R-MTR-1121138] D-alanine--D-alanine ligase - Medicago truncatula [Reaction:R-ATR-1121138] D-alanine--D-alanine ligase - Amborella trichopoda [Reaction:R-CRU-1121138] D-alanine--D-alanine ligase - Capsella rubella [Reaction:R-PED-1121138] D-alanine--D-alanine ligase - Phyllostachys edulis [Reaction:R-CST-1121138] D-alanine--D-alanine ligase - Camelina sativa [Reaction:R-CRE-1121138] D-alanine--D-alanine ligase - Chlamydomonas reinhardtii [Reaction:R-STU-1121138] D-alanine--D-alanine ligase - Solanum tuberosum [Reaction:R-AIP-1121138] D-alanine--D-alanine ligase - Arachis ipaensis [Reaction:R-LSA-1121138] D-alanine--D-alanine ligase - Lactuca sativa [Reaction:R-SCR-1121138] D-alanine--D-alanine ligase - Secale cereale [Reaction:R-TDI-1121138] D-alanine--D-alanine ligase - Triticum dicoccoides [Reaction:R-ONI-1121138] D-alanine--D-alanine ligase - Oryza nivara [Reaction:R-BVU-1121138] D-alanine--D-alanine ligase - Beta vulgaris [Reaction:R-BDI-1121138] D-alanine--D-alanine ligase - Brachypodium distachyon [Reaction:R-ZJA-1121138] D-alanine--D-alanine ligase - Zoysia japonica [Reaction:R-CCD-1121138] D-alanine--D-alanine ligase - Cynara cardunculus var. scolymus [Reaction:R-PPA-1121138] D-alanine--D-alanine ligase - Physcomitrella patens [Reaction:R-SIN-1121138] D-alanine--D-alanine ligase - Sesamum indicum [Reaction:R-ITR-1121138] D-alanine--D-alanine ligase - Ipomoea triloba [Reaction:R-AUM-1121138] D-alanine--D-alanine ligase - Aegilops umbellulata [Reaction:R-DEX-1121138] D-alanine--D-alanine ligase - Digitaria exilis [Reaction:R-PVU-1121138] D-alanine--D-alanine ligase - Phaseolus vulgaris [Reaction:R-LPR-1121138] D-alanine--D-alanine ligase - Lolium perenne [Reaction:R-LAN-1121138] D-alanine--D-alanine ligase - Lupinus angustifolius [Reaction:R-SLY-1121138] D-alanine--D-alanine ligase - Solanum lycopersicum [Reaction:R-PVE-1121138] D-alanine--D-alanine ligase - Pistacia vera [Reaction:R-OSI-1121138] D-alanine--D-alanine ligase - Oryza sativa Indica Group [Reaction:R-CLA-1121138] D-alanine--D-alanine ligase - Citrullus lanatus [Reaction:R-ECG-1121138] D-alanine--D-alanine ligase - Echinochloa crus-galli [Reaction:R-FVE-1121138] D-alanine--D-alanine ligase - Fragaria vesca [Reaction:R-MGU-1121138] D-alanine--D-alanine ligase - Erythranthe guttata [Reaction:R-TTI-1121138] D-alanine--D-alanine ligase - Triticum timopheevii subsp. timopheevii [Reaction:R-CQI-1121138] D-alanine--D-alanine ligase - Chenopodium quinoa [Reaction:R-PHA-1121138] D-alanine--D-alanine ligase - Panicum hallii ("FIL2") [Reaction:R-PHH-1121138] D-alanine--D-alanine ligase - Panicum hallii var. hallii ("HAL2") [Reaction:R-MDO-1121138] D-alanine--D-alanine ligase - Malus domestica [Reaction:R-BJU-1121138] D-alanine--D-alanine ligase - Brassica juncea [Reaction:R-QSU-1121138] D-alanine--D-alanine ligase - Quercus suber [Reaction:R-CCL-1121138] D-alanine--D-alanine ligase - Citrus clementina [Reaction:R-EGR-1121138] D-alanine--D-alanine ligase - Eucalyptus grandis [Reaction:R-DRO-1121138] D-alanine--D-alanine ligase - Dioscorea rotundata [Reaction:R-AHY-1121138] D-alanine--D-alanine ligase - Arachis hypogaea [Reaction:R-OBA-1121138] D-alanine--D-alanine ligase - Oryza barthii [Reaction:R-JCU-1121138] D-alanine--D-alanine ligase - Jatropha curcas [Reaction:R-VRA-1121138] D-alanine--D-alanine ligase - Vigna radiata [Reaction:R-OLU-1121138] D-alanine--D-alanine ligase - Ostreococcus lucimarinus [Reaction:R-SIT-1121138] D-alanine--D-alanine ligase - Setaria italica [Reaction:R-ACO-1121138] D-alanine--D-alanine ligase - Ananas comosus [Reaction:R-CCI-1121138] D-alanine--D-alanine ligase - Corymbia citriodora [Reaction:R-LST-1121138] D-alanine--D-alanine ligase - Lathyrus sativus [Reaction:R-OMI-1121138] D-alanine--D-alanine ligase - Oryza minuta [Reaction:R-PTI-1121138] D-alanine--D-alanine ligase - Populus trichocarpa [Reaction:R-AOF-1121138] D-alanine--D-alanine ligase - Asparagus officinalis [Reaction:R-OGR-1121138] D-alanine--D-alanine ligase - Oryza meyeriana var. granulata [Reaction:R-DCA-1121138] D-alanine--D-alanine ligase - Daucus carota [Reaction:R-ATH-1121138] D-alanine--D-alanine ligase - Arabidopsis thaliana [Reaction:R-FCR-1121138] D-alanine--D-alanine ligase - Ficus carica [Reaction:R-ORU-1121138] D-alanine--D-alanine ligase - Oryza rufipogon [Reaction:R-SSP-1121138] D-alanine--D-alanine ligase - Saccharum spontaneum [Reaction:R-GMA-1121138] D-alanine--D-alanine ligase - Glycine max [Reaction:R-ATA-1121138] D-alanine--D-alanine ligase - Aegilops tauschii [Reaction:R-CML-1121138] D-alanine--D-alanine ligase - Cucumis melo [Reaction:R-VVN-1121138] D-alanine--D-alanine ligase - Vitis vinifera [Reaction:R-GRA-1121138] D-alanine--D-alanine ligase - Gossypium raimondii [Reaction:R-OGL-1121138] D-alanine--D-alanine ligase - Oryza glaberrima [Reaction:R-BNA-1121138] D-alanine--D-alanine ligase - Brassica napus [Reaction:R-CBA-1121138] D-alanine--D-alanine ligase - Chara braunii [Reaction:R-VUN-1121138] D-alanine--D-alanine ligase - Vigna unguiculata [Reaction:R-COL-1121138] D-alanine--D-alanine ligase - Corchorus olitorius [Reaction:R-HLP-1121138] D-alanine--D-alanine ligase - Humulus lupulus var. lupulus [Reaction:R-NAT-1121138] D-alanine--D-alanine ligase - Nicotiana attenuata [Reaction:R-NCO-1121138] D-alanine--D-alanine ligase - Nymphaea colorata [Reaction:R-SPC-1121138] D-alanine--D-alanine ligase - Synechocystis sp. PCC 6803 [Reaction:R-SVI-1121138] D-alanine--D-alanine ligase - Setaria viridis [Reaction:R-MAC-1121138] D-alanine--D-alanine ligase - Musa acuminata
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-1131952] D-alanyl-D-alanine [cytoplasm] [SimpleEntity:R-ALL-29372] Pi [cytosol]
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1121138
summation	[Summation:3239842] D-alanine is converted into D-alanyl-D-alanine by enzymatic ...

Referrals

(hasEvent)	[Pathway:R-OSA-1119436] Peptidoglycan biosynthesis I - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-1120868] UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl- D-alanine ligase - Oryza sativa