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biotin synthase

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catalystActivity	[CatalystActivity:1118519] biotin synthase activity of biotin synthase (LOC_OS08G42730.1) [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:27355] EC:2.8.1.6 [DatabaseIdentifier:1138562] RiceCyc:RXN-5984
dbId	1121121
displayName	biotin synthase
eventOf	[Pathway:R-OSA-1119610] Biotin biosynthesis II - Oryza sativa
followingEvent	[Reaction:R-OSA-1120139] biotin synthase - Oryza sativa
input	[OtherEntity:R-ALL-1131485] a sulfur donor [cytosol] [OtherEntity:R-ALL-1131438] a sulfurated sulfur donor [cytosol] [SimpleEntity:R-ALL-1131496] dethiobiotin [cytosol]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11529250] Elser, Justin, 2025-03-27
name	biotin synthase a sulfurated sulfur donor+a sulfur donor+dethiobiotin->an unsulfurated sulfur acceptor+9-mercaptodethiobiotin RXN-5984 biochemicalReaction39615
orthologousEvent	[Reaction:R-ATA-1121121] biotin synthase - Aegilops tauschii [Reaction:R-RCH-1121121] biotin synthase - Rosa chinensis [Reaction:R-PED-1121121] biotin synthase - Phyllostachys edulis [Reaction:R-AHY-1121121] biotin synthase - Arachis hypogaea [Reaction:R-CCL-1121121] biotin synthase - Citrus clementina [Reaction:R-CCP-1121121] biotin synthase - Corchorus capsularis [Reaction:R-VVN-1121121] biotin synthase - Vitis vinifera [Reaction:R-DCA-1121121] biotin synthase - Daucus carota [Reaction:R-PTI-1121121] biotin synthase - Populus trichocarpa [Reaction:R-HAN-1121121] biotin synthase - Helianthus annuus [Reaction:R-CML-1121121] biotin synthase - Cucumis melo [Reaction:R-BOL-1121121] biotin synthase - Brassica oleracea [Reaction:R-LST-1121121] biotin synthase - Lathyrus sativus [Reaction:R-ORU-1121121] biotin synthase - Oryza rufipogon [Reaction:R-PTA-1121121] biotin synthase - Pinus taeda [Reaction:R-PSA-1121121] biotin synthase - Pisum sativum [Reaction:R-QLO-1121121] biotin synthase - Quercus lobata [Reaction:R-CCA-1121121] biotin synthase - Cajanus cajan [Reaction:R-CSA-1121121] biotin synthase - Cucumis sativus [Reaction:R-ACH-1121121] biotin synthase - Actinidia chinensis [Reaction:R-ACO-1121121] biotin synthase - Ananas comosus [Reaction:R-AIP-1121121] biotin synthase - Arachis ipaensis [Reaction:R-MDO-1121121] biotin synthase - Malus domestica [Reaction:R-PHH-1121121] biotin synthase - Panicum hallii var. hallii ("HAL2") [Reaction:R-OBA-1121121] biotin synthase - Oryza barthii [Reaction:R-CLA-1121121] biotin synthase - Citrullus lanatus [Reaction:R-SMO-1121121] biotin synthase - Selaginella moellendorffii [Reaction:R-DRO-1121121] biotin synthase - Dioscorea rotundata [Reaction:R-COL-1121121] biotin synthase - Corchorus olitorius [Reaction:R-QSU-1121121] biotin synthase - Quercus suber [Reaction:R-OES-1121121] biotin synthase - Olea europaea var. sylvestris [Reaction:R-CAN-1121121] biotin synthase - Capsicum annuum [Reaction:R-SCR-1121121] biotin synthase - Secale cereale [Reaction:R-ASA-1121121] biotin synthase - Avena sativa [Reaction:R-GSO-1121121] biotin synthase - Glycine soja [Reaction:R-VRA-1121121] biotin synthase - Vigna radiata [Reaction:R-TPR-1121121] biotin synthase - Trifolium pratense [Reaction:R-OLU-1121121] biotin synthase - Ostreococcus lucimarinus [Reaction:R-JCU-1121121] biotin synthase - Jatropha curcas [Reaction:R-BNA-1121121] biotin synthase - Brassica napus [Reaction:R-ITR-1121121] biotin synthase - Ipomoea triloba [Reaction:R-CCD-1121121] biotin synthase - Cynara cardunculus var. scolymus [Reaction:R-JRE-1121121] biotin synthase - Juglans regia [Reaction:R-CRE-1121121] biotin synthase - Chlamydomonas reinhardtii [Reaction:R-DEX-1121121] biotin synthase - Digitaria exilis [Reaction:R-FVE-1121121] biotin synthase - Fragaria vesca [Reaction:R-ZJA-1121121] biotin synthase - Zoysia japonica [Reaction:R-PVE-1121121] biotin synthase - Pistacia vera [Reaction:R-VUN-1121121] biotin synthase - Vigna unguiculata [Reaction:R-TSP-1121121] biotin synthase - Triticum spelta subsp. spelta [Reaction:R-HLH-1121121] biotin synthase - Humulus lupulus [Reaction:R-VFA-1121121] biotin synthase - Vicia faba var. faba [Reaction:R-GRA-1121121] biotin synthase - Gossypium raimondii [Reaction:R-ZMY-1121121] biotin synthase - Zea mays ver5 [Reaction:R-AUM-1121121] biotin synthase - Aegilops umbellulata [Reaction:R-CST-1121121] biotin synthase - Camelina sativa [Reaction:R-SBI-1121121] biotin synthase - Sorghum bicolor [Reaction:R-CSI-1121121] biotin synthase - Citrus sinensis [Reaction:R-OKA-1121121] biotin synthase - Oryza sativa aus subgroup [Reaction:R-CRU-1121121] biotin synthase - Capsella rubella [Reaction:R-OME-1121121] biotin synthase - Oryza meridionalis [Reaction:R-NAT-1121121] biotin synthase - Nicotiana attenuata [Reaction:R-PAB-1121121] biotin synthase - Picea abies [Reaction:R-OGL-1121121] biotin synthase - Oryza glaberrima [Reaction:R-NCO-1121121] biotin synthase - Nymphaea colorata [Reaction:R-PAV-1121121] biotin synthase - Prunus avium [Reaction:R-MAC-1121121] biotin synthase - Musa acuminata [Reaction:R-CSK-1121121] biotin synthase - Cannabis sativa subsp. indica [Reaction:R-OAU-1121121] biotin synthase - Oryza australiensis [Reaction:R-CME-1121121] biotin synthase - Cyanidioschyzon merolae [Reaction:R-AOF-1121121] biotin synthase - Asparagus officinalis [Reaction:R-OMI-1121121] biotin synthase - Oryza minuta [Reaction:R-CCI-1121121] biotin synthase - Corymbia citriodora [Reaction:R-CSC-1121121] biotin synthase - Cannabis sativa [Reaction:R-OSI-1121121] biotin synthase - Oryza sativa Indica Group [Reaction:R-SPC-1121121] biotin synthase - Synechocystis sp. PCC 6803 [Reaction:R-OEU-1121121] biotin synthase - Olea europaea [Reaction:R-BRA-1121121] biotin synthase - Brassica rapa [Reaction:R-SSP-1121121] biotin synthase - Saccharum spontaneum [Reaction:R-GMA-1121121] biotin synthase - Glycine max [Reaction:R-PDA-1121121] biotin synthase - Phoenix dactylifera [Reaction:R-LPR-1121121] biotin synthase - Lolium perenne [Reaction:R-FEX-1121121] biotin synthase - Fraxinus excelsior (European ash) [Reaction:R-GSU-1121121] biotin synthase - Galdieria sulphuraria [Reaction:R-OGR-1121121] biotin synthase - Oryza meyeriana var. granulata [Reaction:R-CAR-1121121] biotin synthase - Cicer arietinum [Reaction:R-TTI-1121121] biotin synthase - Triticum timopheevii subsp. timopheevii [Reaction:R-PHA-1121121] biotin synthase - Panicum hallii ("FIL2") [Reaction:R-PVU-1121121] biotin synthase - Phaseolus vulgaris [Reaction:R-ALY-1121121] biotin synthase - Arabidopsis lyrata [Reaction:R-BJU-1121121] biotin synthase - Brassica juncea [Reaction:R-OOF-1121121] biotin synthase - Oryza officinalis [Reaction:R-TCA-1121121] biotin synthase - Theobroma cacao [Reaction:R-OPU-1121121] biotin synthase - Oryza punctata [Reaction:R-AHA-1121121] biotin synthase - Arabidopsis halleri [Reaction:R-PPA-1121121] biotin synthase - Physcomitrella patens [Reaction:R-SIT-1121121] biotin synthase - Setaria italica [Reaction:R-TAE-1121121] biotin synthase - Triticum aestivum [Reaction:R-CCR-1121121] biotin synthase - Chondrus crispus [Reaction:R-ECU-1121121] biotin synthase - Eragrostis curvula [Reaction:R-OBR-1121121] biotin synthase - Oryza brachyantha [Reaction:R-ZMA-1121121] biotin synthase - Zea mays [Reaction:R-TDI-1121121] biotin synthase - Triticum dicoccoides [Reaction:R-NNU-1121121] biotin synthase - Nelumbo nucifera [Reaction:R-ONI-1121121] biotin synthase - Oryza nivara [Reaction:R-EGR-1121121] biotin synthase - Eucalyptus grandis [Reaction:R-OGU-1121121] biotin synthase - Oryza glumaepatula [Reaction:R-ATR-1121121] biotin synthase - Amborella trichopoda [Reaction:R-STU-1121121] biotin synthase - Solanum tuberosum [Reaction:R-LPE-1121121] biotin synthase - Leersia perrieri [Reaction:R-BVU-1121121] biotin synthase - Beta vulgaris [Reaction:R-ECG-1121121] biotin synthase - Echinochloa crus-galli [Reaction:R-SLY-1121121] biotin synthase - Solanum lycopersicum [Reaction:R-MGU-1121121] biotin synthase - Erythranthe guttata [Reaction:R-SIN-1121121] biotin synthase - Sesamum indicum [Reaction:R-MES-1121121] biotin synthase - Manihot esculenta [Reaction:R-CBA-1121121] biotin synthase - Chara braunii [Reaction:R-ATH-1121121] biotin synthase - Arabidopsis thaliana [Reaction:R-ADU-1121121] biotin synthase - Arachis duranensis [Reaction:R-TUR-1121121] biotin synthase - Triticum urartu [Reaction:R-VAN-1121121] biotin synthase - Vigna angularis [Reaction:R-BDI-1121121] biotin synthase - Brachypodium distachyon [Reaction:R-MPO-1121121] biotin synthase - Marchantia polymorpha [Reaction:R-TTU-1121121] biotin synthase - Triticum turgidum [Reaction:R-LAN-1121121] biotin synthase - Lupinus angustifolius [Reaction:R-OLO-1121121] biotin synthase - Oryza longistaminata [Reaction:R-PSO-1121121] biotin synthase - Papaver somniferum [Reaction:R-FCR-1121121] biotin synthase - Ficus carica [Reaction:R-ETE-1121121] biotin synthase - Eragrostis tef [Reaction:R-CCN-1121121] biotin synthase - Coffea canephora [Reaction:R-PPE-1121121] biotin synthase - Prunus persica [Reaction:R-LSA-1121121] biotin synthase - Lactuca sativa [Reaction:R-SVI-1121121] biotin synthase - Setaria viridis [Reaction:R-MTR-1121121] biotin synthase - Medicago truncatula [Reaction:R-HVU-1121121] biotin synthase - Hordeum vulgare
output	[SimpleEntity:R-ALL-1131359] 9-mercaptodethiobiotin [cytosol] [OtherEntity:R-ALL-1132100] an unsulfurated sulfur acceptor [cytosol]
precedingEvent	[Reaction:R-OSA-1121531] dethiobiotin synthase - Oryza sativa
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1121121
summation	[Summation:2870293] Dethiobiotin is converted to 9-mercaptodethiobiotin by enzym...

Referrals

(hasEvent)	[Pathway:R-OSA-1119610] Biotin biosynthesis II - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-1120139] biotin synthase - Oryza sativa