Plant Reactome Pathway Database - Plant Reactome Pathway Database

Schema > Reaction > Entries

Trans-cinnamate 4-monooxygenase

Go to Details

authored	[InstanceEdit:8861963] Naithani, Sushma, 2016-02-22
catalystActivity	[CatalystActivity:1118425] trans-cinnamate 4-monooxygenase activity of Trans-cinnamate 4-monooxygenase. [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:26669] EC:1.14.13.11 [DatabaseIdentifier:1150985] RiceCyc:TRANS-CINNAMATE-4-MONOOXYGENASE-RXN
dbId	1120971
displayName	Trans-cinnamate 4-monooxygenase
eventOf	[Pathway:R-OSA-1119582] Phenylpropanoid biosynthesis, initial reactions - Oryza sativa [Pathway:R-OSA-1119418] Suberin biosynthesis - Oryza sativa
followingEvent	[Reaction:R-OSA-1120386] 4-coumarate+NADPH+O2->caffeate+H2O+NADP+ - Oryza sativa
input	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-29364] NADPH [cytosol] [SimpleEntity:R-ALL-29368] O2 [cytosol] [SimpleEntity:R-ALL-1130684] trans-cinnamate [cytosol]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	Trans-cinnamate 4-monooxygenase CA4H Cinnamate 4-monooxygenase Cinnamate 4-hydroxylase Cinnamic acid 4-monooxygenase Cinnamic acid 4-hydroxylase biochemicalReaction85291
orthologousEvent	[Reaction:R-OGU-1120971] Trans-cinnamate 4-monooxygenase - Oryza glumaepatula [Reaction:R-ADU-1120971] Trans-cinnamate 4-monooxygenase - Arachis duranensis [Reaction:R-DEX-1120971] Trans-cinnamate 4-monooxygenase - Digitaria exilis [Reaction:R-SIT-1120971] Trans-cinnamate 4-monooxygenase - Setaria italica [Reaction:R-FEX-1120971] Trans-cinnamate 4-monooxygenase - Fraxinus excelsior (European ash) [Reaction:R-HAN-1120971] Trans-cinnamate 4-monooxygenase - Helianthus annuus [Reaction:R-EGR-1120971] Trans-cinnamate 4-monooxygenase - Eucalyptus grandis [Reaction:R-PTA-1120971] Trans-cinnamate 4-monooxygenase - Pinus taeda [Reaction:R-VUN-1120971] Trans-cinnamate 4-monooxygenase - Vigna unguiculata [Reaction:R-OBA-1120971] Trans-cinnamate 4-monooxygenase - Oryza barthii [Reaction:R-TAE-1120971] Trans-cinnamate 4-monooxygenase - Triticum aestivum [Reaction:R-OEU-1120971] Trans-cinnamate 4-monooxygenase - Olea europaea [Reaction:R-SLY-1120971] Trans-cinnamate 4-monooxygenase - Solanum lycopersicum [Reaction:R-TPR-1120971] Trans-cinnamate 4-monooxygenase - Trifolium pratense [Reaction:R-BRA-1120971] Trans-cinnamate 4-monooxygenase - Brassica rapa [Reaction:R-PPE-1120971] Trans-cinnamate 4-monooxygenase - Prunus persica [Reaction:R-CCP-1120971] Trans-cinnamate 4-monooxygenase - Corchorus capsularis [Reaction:R-MGU-1120971] Trans-cinnamate 4-monooxygenase - Erythranthe guttata [Reaction:R-STU-1120971] Trans-cinnamate 4-monooxygenase - Solanum tuberosum [Reaction:R-ECG-1120971] Trans-cinnamate 4-monooxygenase - Echinochloa crus-galli [Reaction:R-LPE-1120971] Trans-cinnamate 4-monooxygenase - Leersia perrieri [Reaction:R-PDA-1120971] Trans-cinnamate 4-monooxygenase - Phoenix dactylifera [Reaction:R-TTI-1120971] Trans-cinnamate 4-monooxygenase - Triticum timopheevii subsp. timopheevii [Reaction:R-ACO-1120971] Trans-cinnamate 4-monooxygenase - Ananas comosus [Reaction:R-SBI-1120971] Trans-cinnamate 4-monooxygenase - Sorghum bicolor [Reaction:R-QLO-1120971] Trans-cinnamate 4-monooxygenase - Quercus lobata [Reaction:R-CCN-1120971] Trans-cinnamate 4-monooxygenase - Coffea canephora [Reaction:R-DCA-1120971] Trans-cinnamate 4-monooxygenase - Daucus carota [Reaction:R-BVU-1120971] Trans-cinnamate 4-monooxygenase - Beta vulgaris [Reaction:R-MDO-1120971] Trans-cinnamate 4-monooxygenase - Malus domestica [Reaction:R-CRU-1120971] Trans-cinnamate 4-monooxygenase - Capsella rubella [Reaction:R-PED-1120971] Trans-cinnamate 4-monooxygenase - Phyllostachys edulis [Reaction:R-CCL-1120971] Trans-cinnamate 4-monooxygenase - Citrus clementina [Reaction:R-BDI-1120971] Trans-cinnamate 4-monooxygenase - Brachypodium distachyon [Reaction:R-CCD-1120971] Trans-cinnamate 4-monooxygenase - Cynara cardunculus var. scolymus [Reaction:R-CCI-1120971] Trans-cinnamate 4-monooxygenase - Corymbia citriodora [Reaction:R-OES-1120971] Trans-cinnamate 4-monooxygenase - Olea europaea var. sylvestris [Reaction:R-OOF-1120971] Trans-cinnamate 4-monooxygenase - Oryza officinalis [Reaction:R-NAT-1120971] Trans-cinnamate 4-monooxygenase - Nicotiana attenuata [Reaction:R-AHY-1120971] Trans-cinnamate 4-monooxygenase - Arachis hypogaea [Reaction:R-CML-1120971] Trans-cinnamate 4-monooxygenase - Cucumis melo [Reaction:R-CLA-1120971] Trans-cinnamate 4-monooxygenase - Citrullus lanatus [Reaction:R-OSI-1120971] Trans-cinnamate 4-monooxygenase - Oryza sativa Indica Group [Reaction:R-PPA-1120971] Trans-cinnamate 4-monooxygenase - Physcomitrella patens [Reaction:R-FCR-1120971] Trans-cinnamate 4-monooxygenase - Ficus carica [Reaction:R-AOF-1120971] Trans-cinnamate 4-monooxygenase - Asparagus officinalis [Reaction:R-TCA-1120971] Trans-cinnamate 4-monooxygenase - Theobroma cacao [Reaction:R-MAC-1120971] Trans-cinnamate 4-monooxygenase - Musa acuminata [Reaction:R-AIP-1120971] Trans-cinnamate 4-monooxygenase - Arachis ipaensis [Reaction:R-ECU-1120971] Trans-cinnamate 4-monooxygenase - Eragrostis curvula [Reaction:R-DRO-1120971] Trans-cinnamate 4-monooxygenase - Dioscorea rotundata [Reaction:R-CSA-1120971] Trans-cinnamate 4-monooxygenase - Cucumis sativus [Reaction:R-CAR-1120971] Trans-cinnamate 4-monooxygenase - Cicer arietinum [Reaction:R-ITR-1120971] Trans-cinnamate 4-monooxygenase - Ipomoea triloba [Reaction:R-ALY-1120971] Trans-cinnamate 4-monooxygenase - Arabidopsis lyrata [Reaction:R-RCH-1120971] Trans-cinnamate 4-monooxygenase - Rosa chinensis [Reaction:R-PHA-1120971] Trans-cinnamate 4-monooxygenase - Panicum hallii ("FIL2") [Reaction:R-PAV-1120971] Trans-cinnamate 4-monooxygenase - Prunus avium [Reaction:R-OBR-1120971] Trans-cinnamate 4-monooxygenase - Oryza brachyantha [Reaction:R-ATR-1120971] Trans-cinnamate 4-monooxygenase - Amborella trichopoda [Reaction:R-QSU-1120971] Trans-cinnamate 4-monooxygenase - Quercus suber [Reaction:R-AUM-1120971] Trans-cinnamate 4-monooxygenase - Aegilops umbellulata [Reaction:R-FVE-1120971] Trans-cinnamate 4-monooxygenase - Fragaria vesca [Reaction:R-ZMA-1120971] Trans-cinnamate 4-monooxygenase - Zea mays [Reaction:R-MPO-1120971] Trans-cinnamate 4-monooxygenase - Marchantia polymorpha [Reaction:R-LPR-1120971] Trans-cinnamate 4-monooxygenase - Lolium perenne [Reaction:R-CAN-1120971] Trans-cinnamate 4-monooxygenase - Capsicum annuum [Reaction:R-SMO-1120971] Trans-cinnamate 4-monooxygenase - Selaginella moellendorffii [Reaction:R-ZJA-1120971] Trans-cinnamate 4-monooxygenase - Zoysia japonica [Reaction:R-CST-1120971] Trans-cinnamate 4-monooxygenase - Camelina sativa [Reaction:R-SIN-1120971] Trans-cinnamate 4-monooxygenase - Sesamum indicum [Reaction:R-PVU-1120971] Trans-cinnamate 4-monooxygenase - Phaseolus vulgaris [Reaction:R-AHA-1120971] Trans-cinnamate 4-monooxygenase - Arabidopsis halleri [Reaction:R-ATA-1120971] Trans-cinnamate 4-monooxygenase - Aegilops tauschii [Reaction:R-CSI-1120971] Trans-cinnamate 4-monooxygenase - Citrus sinensis [Reaction:R-JCU-1120971] Trans-cinnamate 4-monooxygenase - Jatropha curcas [Reaction:R-ATH-1120971] Trans-cinnamate 4-monooxygenase - Arabidopsis thaliana [Reaction:R-NCO-1120971] Trans-cinnamate 4-monooxygenase - Nymphaea colorata [Reaction:R-BNA-1120971] Trans-cinnamate 4-monooxygenase - Brassica napus [Reaction:R-SVI-1120971] Trans-cinnamate 4-monooxygenase - Setaria viridis [Reaction:R-VRA-1120971] Trans-cinnamate 4-monooxygenase - Vigna radiata [Reaction:R-COL-1120971] Trans-cinnamate 4-monooxygenase - Corchorus olitorius [Reaction:R-ETE-1120971] Trans-cinnamate 4-monooxygenase - Eragrostis tef [Reaction:R-SCR-1120971] Trans-cinnamate 4-monooxygenase - Secale cereale [Reaction:R-LAN-1120971] Trans-cinnamate 4-monooxygenase - Lupinus angustifolius [Reaction:R-CSK-1120971] Trans-cinnamate 4-monooxygenase - Cannabis sativa subsp. indica [Reaction:R-BJU-1120971] Trans-cinnamate 4-monooxygenase - Brassica juncea [Reaction:R-BOL-1120971] Trans-cinnamate 4-monooxygenase - Brassica oleracea [Reaction:R-ZMY-1120971] Trans-cinnamate 4-monooxygenase - Zea mays ver5 [Reaction:R-OAU-1120971] Trans-cinnamate 4-monooxygenase - Oryza australiensis [Reaction:R-OGL-1120971] Trans-cinnamate 4-monooxygenase - Oryza glaberrima [Reaction:R-OME-1120971] Trans-cinnamate 4-monooxygenase - Oryza meridionalis [Reaction:R-ASA-1120971] Trans-cinnamate 4-monooxygenase - Avena sativa [Reaction:R-HLP-1120971] Trans-cinnamate 4-monooxygenase - Humulus lupulus var. lupulus [Reaction:R-PAB-1120971] Trans-cinnamate 4-monooxygenase - Picea abies [Reaction:R-ONI-1120971] Trans-cinnamate 4-monooxygenase - Oryza nivara [Reaction:R-MES-1120971] Trans-cinnamate 4-monooxygenase - Manihot esculenta [Reaction:R-SHI-1120971] Trans-cinnamate 4-monooxygenase - Salvia hispanica [Reaction:R-VVN-1120971] Trans-cinnamate 4-monooxygenase - Vitis vinifera [Reaction:R-GRA-1120971] Trans-cinnamate 4-monooxygenase - Gossypium raimondii [Reaction:R-PVE-1120971] Trans-cinnamate 4-monooxygenase - Pistacia vera [Reaction:R-OLO-1120971] Trans-cinnamate 4-monooxygenase - Oryza longistaminata [Reaction:R-MTR-1120971] Trans-cinnamate 4-monooxygenase - Medicago truncatula [Reaction:R-CQI-1120971] Trans-cinnamate 4-monooxygenase - Chenopodium quinoa [Reaction:R-OGR-1120971] Trans-cinnamate 4-monooxygenase - Oryza meyeriana var. granulata [Reaction:R-LST-1120971] Trans-cinnamate 4-monooxygenase - Lathyrus sativus [Reaction:R-PSA-1120971] Trans-cinnamate 4-monooxygenase - Pisum sativum [Reaction:R-VAN-1120971] Trans-cinnamate 4-monooxygenase - Vigna angularis [Reaction:R-OPU-1120971] Trans-cinnamate 4-monooxygenase - Oryza punctata [Reaction:R-TUR-1120971] Trans-cinnamate 4-monooxygenase - Triticum urartu [Reaction:R-TSP-1120971] Trans-cinnamate 4-monooxygenase - Triticum spelta subsp. spelta [Reaction:R-TDI-1120971] Trans-cinnamate 4-monooxygenase - Triticum dicoccoides [Reaction:R-NNU-1120971] Trans-cinnamate 4-monooxygenase - Nelumbo nucifera [Reaction:R-SSP-1120971] Trans-cinnamate 4-monooxygenase - Saccharum spontaneum [Reaction:R-PTI-1120971] Trans-cinnamate 4-monooxygenase - Populus trichocarpa [Reaction:R-PHH-1120971] Trans-cinnamate 4-monooxygenase - Panicum hallii var. hallii ("HAL2") [Reaction:R-PSO-1120971] Trans-cinnamate 4-monooxygenase - Papaver somniferum [Reaction:R-VFA-1120971] Trans-cinnamate 4-monooxygenase - Vicia faba var. faba [Reaction:R-JRE-1120971] Trans-cinnamate 4-monooxygenase - Juglans regia [Reaction:R-LSA-1120971] Trans-cinnamate 4-monooxygenase - Lactuca sativa [Reaction:R-CSC-1120971] Trans-cinnamate 4-monooxygenase - Cannabis sativa [Reaction:R-TTU-1120971] Trans-cinnamate 4-monooxygenase - Triticum turgidum [Reaction:R-OMI-1120971] Trans-cinnamate 4-monooxygenase - Oryza minuta [Reaction:R-GSO-1120971] Trans-cinnamate 4-monooxygenase - Glycine soja [Reaction:R-ORU-1120971] Trans-cinnamate 4-monooxygenase - Oryza rufipogon [Reaction:R-GMA-1120971] Trans-cinnamate 4-monooxygenase - Glycine max [Reaction:R-ACH-1120971] Trans-cinnamate 4-monooxygenase - Actinidia chinensis
output	[SimpleEntity:R-ALL-1130542] 4-coumarate [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-29366] NADP+ [cytosol]
precedingEvent	[Reaction:R-OSA-1120727] Phenylalanine ammonia-lyase - Oryza sativa
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1120971
summation	[Summation:2882016] Trans-cinnamate is converted into 4-coumarate by enzymatic a...

Referrals

(hasEvent)	[Pathway:R-OSA-1119582] Phenylpropanoid biosynthesis, initial reactions - Oryza sativa [Pathway:R-OSA-1119418] Suberin biosynthesis - Oryza sativa
(precedingEvent)	[Reaction:R-OSA-1120386] 4-coumarate+NADPH+O2->caffeate+H2O+NADP+ - Oryza sativa