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a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP

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catalystActivity	[CatalystActivity:1118293] long-chain fatty acid-CoA ligase activity of Long-chain-fatty-acid--CoA ligase. [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1164949] Wu, Guanming, 2010-12-11
crossReference	[DatabaseIdentifier:28125] EC:6.2.1.3 [DatabaseIdentifier:1146966] RiceCyc:RXN-7904
dbId	1120638
displayName	a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP
eventOf	[Pathway:R-OSA-1119623] Acyl-CoA synthetase pathway - Oryza sativa
input	[SimpleEntity:R-ALL-1131221] a fatty acid [cytosol] [SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-76194] CoA-SH [cytosol]
isInDisease	false
isInferred	false
modified	[InstanceEdit:11540225] Elser, Justin, 2025-03-27
name	a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP RXN-7904 biochemicalReaction7085
orthologousEvent	[Reaction:R-CCN-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Coffea canephora [Reaction:R-OPU-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Oryza punctata [Reaction:R-PSO-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Papaver somniferum [Reaction:R-DEX-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Digitaria exilis [Reaction:R-AIP-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Arachis ipaensis [Reaction:R-TUR-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Triticum urartu [Reaction:R-SBI-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Sorghum bicolor [Reaction:R-ITR-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Ipomoea triloba [Reaction:R-BVU-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Beta vulgaris [Reaction:R-CLA-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Citrullus lanatus [Reaction:R-CST-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Camelina sativa [Reaction:R-SHI-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Salvia hispanica [Reaction:R-OGR-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Oryza meyeriana var. granulata [Reaction:R-PVE-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Pistacia vera [Reaction:R-OMI-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Oryza minuta [Reaction:R-STU-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Solanum tuberosum [Reaction:R-PTA-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Pinus taeda [Reaction:R-ASA-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Avena sativa [Reaction:R-COL-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Corchorus olitorius [Reaction:R-QLO-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Quercus lobata [Reaction:R-CML-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Cucumis melo [Reaction:R-OLO-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Oryza longistaminata [Reaction:R-ATR-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Amborella trichopoda [Reaction:R-OBR-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Oryza brachyantha [Reaction:R-JCU-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Jatropha curcas [Reaction:R-CCP-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Corchorus capsularis [Reaction:R-OOF-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Oryza officinalis [Reaction:R-ZJA-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Zoysia japonica [Reaction:R-BOL-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Brassica oleracea [Reaction:R-DRO-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Dioscorea rotundata [Reaction:R-CAN-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Capsicum annuum [Reaction:R-VFA-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Vicia faba var. faba [Reaction:R-CSK-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Cannabis sativa subsp. indica [Reaction:R-TDI-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Triticum dicoccoides [Reaction:R-BDI-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Brachypodium distachyon [Reaction:R-SSP-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Saccharum spontaneum [Reaction:R-OKA-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Oryza sativa aus subgroup [Reaction:R-ECU-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Eragrostis curvula [Reaction:R-LPR-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Lolium perenne [Reaction:R-VUN-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Vigna unguiculata [Reaction:R-SLY-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Solanum lycopersicum [Reaction:R-PAB-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Picea abies [Reaction:R-ZMY-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Zea mays ver5 [Reaction:R-TTU-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Triticum turgidum [Reaction:R-CAR-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Cicer arietinum [Reaction:R-OEU-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Olea europaea [Reaction:R-SIN-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Sesamum indicum [Reaction:R-HAN-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Helianthus annuus [Reaction:R-SCR-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Secale cereale [Reaction:R-CQI-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Chenopodium quinoa [Reaction:R-PPE-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Prunus persica [Reaction:R-HLP-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Humulus lupulus var. lupulus [Reaction:R-NCO-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Nymphaea colorata [Reaction:R-EGR-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Eucalyptus grandis [Reaction:R-GSO-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Glycine soja [Reaction:R-PTI-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Populus trichocarpa [Reaction:R-PED-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Phyllostachys edulis [Reaction:R-PHA-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Panicum hallii ("FIL2") [Reaction:R-DCA-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Daucus carota [Reaction:R-OGU-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Oryza glumaepatula [Reaction:R-OBA-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Oryza barthii [Reaction:R-OGL-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Oryza glaberrima [Reaction:R-PSA-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Pisum sativum [Reaction:R-CCA-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Cajanus cajan [Reaction:R-ATA-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Aegilops tauschii [Reaction:R-MDO-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Malus domestica [Reaction:R-NAT-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Nicotiana attenuata [Reaction:R-TPR-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Trifolium pratense [Reaction:R-PVU-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Phaseolus vulgaris [Reaction:R-CCL-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Citrus clementina [Reaction:R-CRU-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Capsella rubella [Reaction:R-OSI-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Oryza sativa Indica Group [Reaction:R-CCD-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Cynara cardunculus var. scolymus [Reaction:R-VAN-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Vigna angularis [Reaction:R-CSC-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Cannabis sativa [Reaction:R-QSU-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Quercus suber [Reaction:R-AHY-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Arachis hypogaea [Reaction:R-BRA-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Brassica rapa [Reaction:R-MGU-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Erythranthe guttata [Reaction:R-MTR-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Medicago truncatula [Reaction:R-ATH-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Arabidopsis thaliana [Reaction:R-SVI-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Setaria viridis [Reaction:R-ACO-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Ananas comosus [Reaction:R-TAE-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Triticum aestivum [Reaction:R-FVE-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Fragaria vesca [Reaction:R-MAC-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Musa acuminata [Reaction:R-PAV-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Prunus avium [Reaction:R-AOF-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Asparagus officinalis [Reaction:R-NNU-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Nelumbo nucifera [Reaction:R-ADU-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Arachis duranensis [Reaction:R-TSP-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Triticum spelta subsp. spelta [Reaction:R-TCA-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Theobroma cacao [Reaction:R-LSA-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Lactuca sativa [Reaction:R-ONI-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Oryza nivara [Reaction:R-BJU-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Brassica juncea [Reaction:R-PPA-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Physcomitrella patens [Reaction:R-OES-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Olea europaea var. sylvestris [Reaction:R-BNA-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Brassica napus [Reaction:R-SIT-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Setaria italica [Reaction:R-CSA-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Cucumis sativus [Reaction:R-LAN-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Lupinus angustifolius [Reaction:R-MPO-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Marchantia polymorpha [Reaction:R-GMA-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Glycine max [Reaction:R-SMO-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Selaginella moellendorffii [Reaction:R-ETE-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Eragrostis tef [Reaction:R-TTI-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Triticum timopheevii subsp. timopheevii [Reaction:R-MES-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Manihot esculenta [Reaction:R-LPE-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Leersia perrieri [Reaction:R-AHA-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Arabidopsis halleri [Reaction:R-ECG-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Echinochloa crus-galli [Reaction:R-PHH-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Panicum hallii var. hallii ("HAL2") [Reaction:R-ORU-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Oryza rufipogon [Reaction:R-GRA-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Gossypium raimondii [Reaction:R-ALY-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Arabidopsis lyrata [Reaction:R-ACH-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Actinidia chinensis [Reaction:R-JRE-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Juglans regia [Reaction:R-RCH-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Rosa chinensis [Reaction:R-HVU-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Hordeum vulgare [Reaction:R-PDA-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Phoenix dactylifera [Reaction:R-VVN-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Vitis vinifera [Reaction:R-FEX-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Fraxinus excelsior (European ash) [Reaction:R-OME-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Oryza meridionalis [Reaction:R-ZMA-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Zea mays [Reaction:R-OAU-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Oryza australiensis [Reaction:R-CSI-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Citrus sinensis [Reaction:R-CCI-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Corymbia citriodora [Reaction:R-FCR-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Ficus carica [Reaction:R-LST-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Lathyrus sativus [Reaction:R-VRA-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Vigna radiata [Reaction:R-AUM-1120638] a fatty acid+coenzyme A+ATP->a fatty acyl CoA+diphosphate+AMP - Aegilops umbellulata
output	[SimpleEntity:R-ALL-76577] AMP [cytosol] [SimpleEntity:R-ALL-75967] FACoA [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol]
schemaClass	Reaction
species	[Species:186860] Oryza sativa
stId	R-OSA-1120638
summation	[Summation:3900999] A fatty acid is converted into a fatty acyl CoA by enzymatic...

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(hasEvent)

[Pathway:R-OSA-1119623] Acyl-CoA synthetase pathway - Oryza sativa

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